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Chlamydial infection

MedGen UID:
40237
•Concept ID:
C0008149
•
Disease or Syndrome
Synonyms: Chlamydia Infection; Chlamydia Infections; Infection, Chlamydia; Infections, Chlamydia
SNOMED CT: Chlamydial infection (105629000)

Definition

An infection that is caused by Chlamydia trachomatis. [from NCI]

Professional guidelines

PubMed

Chlamydia trachomatis Screening and Treatment in Pregnancy to Reduce Adverse Pregnancy and Neonatal Outcomes: A Review.
Adachi KN, Nielsen-Saines K, Klausner JD
Front Public Health 2021;9:531073. Epub 2021 Jun 10 doi: 10.3389/fpubh.2021.531073. PMID: 34178906Free PMC Article
Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020.
St Cyr S, Barbee L, Workowski KA, Bachmann LH, Pham C, Schlanger K, Torrone E, Weinstock H, Kersh EN, Thorpe P
MMWR Morb Mortal Wkly Rep 2020 Dec 18;69(50):1911-1916. doi: 10.15585/mmwr.mm6950a6. PMID: 33332296Free PMC Article
Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.
Zikic A, Schünemann H, Wi T, Lincetto O, Broutet N, Santesso N
J Pediatric Infect Dis Soc 2018 Aug 17;7(3):e107-e115. doi: 10.1093/jpids/piy060. PMID: 30007329Free PMC Article

Recent clinical studies

Etiology

Sociodemographic Factors Associated With Gonorrhea and Chlamydia Infection in Pregnancy.
Gulersen M, Lenchner E, Eliner Y, Grunebaum A, Chervenak FA, Bornstein E
Sex Transm Dis 2022 Nov 1;49(11):750-754. Epub 2022 Aug 6 doi: 10.1097/OLQ.0000000000001688. PMID: 35948286
Chlamydia infection, PID, and infertility: further evidence from a case-control study in China.
Liu L, Li C, Sun X, Liu J, Zheng H, Yang B, Tang W, Wang C
BMC Womens Health 2022 Jul 15;22(1):294. doi: 10.1186/s12905-022-01874-z. PMID: 35840924Free PMC Article
Chlamydial polymorphic membrane proteins: regulation, function and potential vaccine candidates.
Vasilevsky S, Stojanov M, Greub G, Baud D
Virulence 2016;7(1):11-22. Epub 2015 Nov 18 doi: 10.1080/21505594.2015.1111509. PMID: 26580416Free PMC Article
Trachoma and Ocular Chlamydial Infection in the Era of Genomics.
Derrick T, Roberts Ch, Last AR, Burr SE, Holland MJ
Mediators Inflamm 2015;2015:791847. Epub 2015 Sep 3 doi: 10.1155/2015/791847. PMID: 26424969Free PMC Article
Chlamydia trachomatis: time for screening?
Spiliopoulou A, Lakiotis V, Vittoraki A, Zavou D, Mauri D
Clin Microbiol Infect 2005 Sep;11(9):687-9. doi: 10.1111/j.1469-0691.2005.01187.x. PMID: 16104982

Diagnosis

AAUS guideline for chlamydial urethritis.
Hiyama Y, Takahashi S, Yasuda M
J Infect Chemother 2022 Feb;28(2):142-145. Epub 2021 Dec 7 doi: 10.1016/j.jiac.2021.11.024. PMID: 34887176
Laboratory diagnosis of persistent human chlamydial infection.
Puolakkainen M
Front Cell Infect Microbiol 2013;3:99. Epub 2013 Dec 17 doi: 10.3389/fcimb.2013.00099. PMID: 24381934Free PMC Article
Recognition and treatment of chlamydial infections from birth to adolescence.
Darville T
Adv Exp Med Biol 2013;764:109-22. doi: 10.1007/978-1-4614-4726-9_8. PMID: 23654060
Diagnosis and treatment of Chlamydia trachomatis infection.
Miller KE
Am Fam Physician 2006 Apr 15;73(8):1411-6. PMID: 16669564
Chlamydia trachomatis: time for screening?
Spiliopoulou A, Lakiotis V, Vittoraki A, Zavou D, Mauri D
Clin Microbiol Infect 2005 Sep;11(9):687-9. doi: 10.1111/j.1469-0691.2005.01187.x. PMID: 16104982

Therapy

Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020.
St Cyr S, Barbee L, Workowski KA, Bachmann LH, Pham C, Schlanger K, Torrone E, Weinstock H, Kersh EN, Thorpe P
MMWR Morb Mortal Wkly Rep 2020 Dec 18;69(50):1911-1916. doi: 10.15585/mmwr.mm6950a6. PMID: 33332296Free PMC Article
Gonorrhea, a current disease with ancient roots: from the remedies of the past to future perspectives.
Vicentini CB, Manfredini S, Maritati M, Di Nuzzo M, Contini C
Infez Med 2019 Jun 1;27(2):212-221. PMID: 31205048
Chlamydia (uncomplicated, genital).
Crofts M, Horner P
BMJ Clin Evid 2015 Apr 16;2015 PMID: 25880031Free PMC Article
Chlamydial biology and its associated virulence blockers.
Beeckman DS, De Puysseleyr L, De Puysseleyr K, Vanrompay D
Crit Rev Microbiol 2014 Nov;40(4):313-28. Epub 2012 Nov 7 doi: 10.3109/1040841X.2012.726210. PMID: 23134414
Chlamydia (uncomplicated, genital).
Horner P
BMJ Clin Evid 2010 Apr 22;2010 PMID: 21718568Free PMC Article

Prognosis

Interleukin-27 (IL-27) Promotes Chlamydial Infection in the Female Genital Tract.
Zhao Y, Huo Z, Zhou Z, Cervantes C, Chen J, Xu Z, Zhong G
Infect Immun 2022 Apr 21;90(4):e0065121. Epub 2022 Mar 8 doi: 10.1128/iai.00651-21. PMID: 35258318Free PMC Article
A Review of the Challenges and Complexities in the Diagnosis, Etiology, Epidemiology, and Pathogenesis of Pelvic Inflammatory Disease.
Hillier SL, Bernstein KT, Aral S
J Infect Dis 2021 Aug 16;224(12 Suppl 2):S23-S28. doi: 10.1093/infdis/jiab116. PMID: 34396398Free PMC Article
Infections caused by Chlamydophila pneumoniae.
Choroszy-Król I, Frej-Mądrzak M, Hober M, Sarowska J, Jama-Kmiecik A
Adv Clin Exp Med 2014 Jan-Feb;23(1):123-6. doi: 10.17219/acem/37035. PMID: 24596014
Chlamydia and chronic arthritis.
Carter JD, Inman RD, Whittum-Hudson J, Hudson AP
Ann Med 2012 Dec;44(8):784-92. Epub 2011 Aug 24 doi: 10.3109/07853890.2011.606830. PMID: 21864020
Abdominal aortic aneurysms.
Lindholt JS
Dan Med Bull 2010 Dec;57(12):B4219. PMID: 21122465

Clinical prediction guides

Interleukin-27 (IL-27) Promotes Chlamydial Infection in the Female Genital Tract.
Zhao Y, Huo Z, Zhou Z, Cervantes C, Chen J, Xu Z, Zhong G
Infect Immun 2022 Apr 21;90(4):e0065121. Epub 2022 Mar 8 doi: 10.1128/iai.00651-21. PMID: 35258318Free PMC Article
Azithromycin in the treatment of rectogenital Chlamydia trachomatis infections: end of an era?
Hammerschlag MR, Sharma R
Expert Rev Anti Infect Ther 2021 Apr;19(4):487-493. Epub 2020 Oct 18 doi: 10.1080/14787210.2021.1834850. PMID: 33034227
Bacterial sexually transmitted infections.
Buder S, Schöfer H, Meyer T, Bremer V, Kohl PK, Skaletz-Rorowski A, Brockmeyer N
J Dtsch Dermatol Ges 2019 Mar;17(3):287-315. doi: 10.1111/ddg.13804. PMID: 30920748
Inhibition of Chlamydia trachomatis Growth During the Last Decade: A Mini-Review.
Serradji N, Vu TH, Kim H, Panyam J, Verbeke P
Mini Rev Med Chem 2018;18(16):1363-1372. doi: 10.2174/1389557518666180423152613. PMID: 29692244
Chlamydia (uncomplicated, genital).
Horner P
BMJ Clin Evid 2010 Apr 22;2010 PMID: 21718568Free PMC Article

Recent systematic reviews

Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.
Zikic A, Schünemann H, Wi T, Lincetto O, Broutet N, Santesso N
J Pediatric Infect Dis Soc 2018 Aug 17;7(3):e107-e115. doi: 10.1093/jpids/piy060. PMID: 30007329Free PMC Article
Chlamydia (uncomplicated, genital).
Crofts M, Horner P
BMJ Clin Evid 2015 Apr 16;2015 PMID: 25880031Free PMC Article
Antibiotics for trachoma.
Evans JR, Solomon AW
Cochrane Database Syst Rev 2011 Mar 16;(3):CD001860. doi: 10.1002/14651858.CD001860.pub3. PMID: 21412875
Chlamydia (uncomplicated, genital).
Horner P
BMJ Clin Evid 2010 Apr 22;2010 PMID: 21718568Free PMC Article
Intrauterine device and upper-genital-tract infection.
Grimes DA
Lancet 2000 Sep 16;356(9234):1013-9. doi: 10.1016/S0140-6736(00)02699-4. PMID: 11041414

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