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Stage IIIB Cutaneous Melanoma AJCC v7

MedGen UID:
416126
•Concept ID:
C2828035
•
Neoplastic Process
Synonym: Stage IIIB Skin Melanoma AJCC v7

Definition

Stage IIIB includes: (T1-4b, N1a, M0); (T1-4b, N2a, M0); (T1-4a, N1b, M0); (T1-4a, N2b, M0); (T1-4a, N2c, M0). T1-4b: Ulcerated cutaneous melanoma of any thickness. T1-4a: Non-ulcerated cutaneous melanoma of any thickness. N1a: Cutaneous melanoma with micrometastasis in one regional lymph node. N2a: Cutaneous melanoma with micrometastases in 2-3 regional lymph nodes. N1b: Cutaneous melanoma with macrometastasis in one regional lymph node. N2b: Cutaneous melanoma with macrometastases in 2-3 regional lymph nodes. N2c: Cutaneous melanoma with intralymphatic metastases (in transit or satellite metastases) without metastatic nodes. M0: No detectable evidence of distant metastases. (from AJCC 7th Ed.) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStage IIIB Cutaneous Melanoma AJCC v7

Recent clinical studies

Etiology

Multicenter, double-blind, placebo-controlled trial of seviprotimut-L polyvalent melanoma vaccine in patients with post-resection melanoma at high risk of recurrence.
Slingluff CL, Lewis KD, Andtbacka R, Hyngstrom J, Milhem M, Markovic SN, Bowles T, Hamid O, Hernandez-Aya L, Claveau J, Jang S, Philips P, Holtan SG, Shaheen MF, Curti B, Schmidt W, Butler MO, Paramo J, Lutzky J, Padmanabhan A, Thomas S, Milton D, Pecora A, Sato T, Hsueh E, Badarinath S, Keech J, Kalmadi S, Kumar P, Weber R, Levine E, Berger A, Bar A, Beck JT, Travers JB, Mihalcioiu C, Gastman B, Beitsch P, Rapisuwon S, Glaspy J, McCarron EC, Gupta V, Behl D, Blumenstein B, Peterkin JJ
J Immunother Cancer 2021 Oct;9(10) doi: 10.1136/jitc-2021-003272. PMID: 34599031Free PMC Article

Therapy

Multicenter, double-blind, placebo-controlled trial of seviprotimut-L polyvalent melanoma vaccine in patients with post-resection melanoma at high risk of recurrence.
Slingluff CL, Lewis KD, Andtbacka R, Hyngstrom J, Milhem M, Markovic SN, Bowles T, Hamid O, Hernandez-Aya L, Claveau J, Jang S, Philips P, Holtan SG, Shaheen MF, Curti B, Schmidt W, Butler MO, Paramo J, Lutzky J, Padmanabhan A, Thomas S, Milton D, Pecora A, Sato T, Hsueh E, Badarinath S, Keech J, Kalmadi S, Kumar P, Weber R, Levine E, Berger A, Bar A, Beck JT, Travers JB, Mihalcioiu C, Gastman B, Beitsch P, Rapisuwon S, Glaspy J, McCarron EC, Gupta V, Behl D, Blumenstein B, Peterkin JJ
J Immunother Cancer 2021 Oct;9(10) doi: 10.1136/jitc-2021-003272. PMID: 34599031Free PMC Article

Supplemental Content

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    • Stage IIIB Cutaneous Melanoma AJCC v7
      Stage IIIB Cutaneous Melanoma AJCC v7
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