U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Recurrent Childhood Spinal Cord Neoplasm

MedGen UID:
417093
•Concept ID:
C2347914
•
Neoplastic Process
Synonym: Recurrent Childhood Spinal Cord Tumor

Definition

The reemergence of a spinal cord neoplasm in childhood after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Childhood Spinal Cord Neoplasm

Professional guidelines

PubMed

Paediatric spinal cord low-grade gliomas-evaluation and management of post-surgical residual disease.
Silva AHD, Constantinides M, Valetopoulou A, Sgardelis P, Mankad K, D'Arco F, Jankovic I, Thompson D
Childs Nerv Syst 2022 Mar;38(3):577-586. Epub 2021 Dec 2 doi: 10.1007/s00381-021-05412-4. PMID: 34855000
Medulloblastoma in childhood: Impact of radiation technique upon the outcome of treatment.
Chojnacka M, Skowrońska-Gardas A
Pediatr Blood Cancer 2004 Feb;42(2):155-60. doi: 10.1002/pbc.10401. PMID: 14752880
Treatment of high-grade spinal cord astrocytoma of childhood with "8-in-1" chemotherapy and radiotherapy: a pilot study of CCG-945. Children's Cancer Group.
Allen JC, Aviner S, Yates AJ, Boyett JM, Cherlow JM, Turski PA, Epstein F, Finlay JL
J Neurosurg 1998 Feb;88(2):215-20. doi: 10.3171/jns.1998.88.2.0215. PMID: 9452226

Recent clinical studies

Etiology

Paediatric spinal cord low-grade gliomas-evaluation and management of post-surgical residual disease.
Silva AHD, Constantinides M, Valetopoulou A, Sgardelis P, Mankad K, D'Arco F, Jankovic I, Thompson D
Childs Nerv Syst 2022 Mar;38(3):577-586. Epub 2021 Dec 2 doi: 10.1007/s00381-021-05412-4. PMID: 34855000
Spinal meningioma in childhood: clinical features and treatment.
Wang XQ, Zeng XW, Zhang BY, Dou YF, Wu JS, Jiang CC, Zhong P, Chen H
Childs Nerv Syst 2012 Jan;28(1):129-36. Epub 2011 Sep 25 doi: 10.1007/s00381-011-1570-2. PMID: 21947034
More is better! Update of Dana-Farber Cancer Institute/Children's Hospital childhood acute lymphoblastic leukemia trials.
Sallan SE, Gelber RD, Kimball V, Donnelly M, Cohen HJ
Haematol Blood Transfus 1990;33:459-66. doi: 10.1007/978-3-642-74643-7_83. PMID: 2182437
Outcome following late marrow relapse in childhood acute lymphoblastic leukemia.
Chessells J, Leiper A, Rogers D
J Clin Oncol 1984 Oct;2(10):1088-91. doi: 10.1200/JCO.1984.2.10.1088. PMID: 6593434
Medulloblastoma in childhood.
Raimondi AJ, Tomita T
Acta Neurochir (Wien) 1979;50(1-2):127-38. doi: 10.1007/BF01813557. PMID: 517184

Diagnosis

Preferential sites of metastatic relapse on MRI of initially localized ependymoma in children.
Rootman MS, Konen O, Fried I, Toledano H
Clin Imaging 2017 Jul-Aug;44:12-15. Epub 2017 Mar 30 doi: 10.1016/j.clinimag.2017.03.015. PMID: 28395190
Surgical treatment of a clival-C2 atypical teratoid/rhabdoid tumor.
Heuer GG, Kiefer H, Judkins AR, Belasco J, Biegel JA, Jackson EM, Cohen M, O'Malley BW Jr, Storm PB
J Neurosurg Pediatr 2010 Jan;5(1):75-9. doi: 10.3171/2009.8.PEDS08421. PMID: 20043739Free PMC Article
Progressive vacuolar myelopathy and leukoencephalopathy in childhood acute lymphoblastic leukemia and transient improvement with vitamin B12.
Olcay L, Irkkan C, Senbil N, Uzun H, Basmaci M, Gürer YK
Pediatr Blood Cancer 2007 Oct 15;49(5):754-8. doi: 10.1002/pbc.20720. PMID: 16395685
Spinal papillary meningioma: a case report and review of the literature.
Meinsma-vdTuin M, Molenaar WM, Mooij JJ
Acta Neurochir (Wien) 2000;142(6):703-8. doi: 10.1007/s007010070116. PMID: 10949447
Medulloblastoma in childhood.
Raimondi AJ, Tomita T
Acta Neurochir (Wien) 1979;50(1-2):127-38. doi: 10.1007/BF01813557. PMID: 517184

Therapy

Neurologic complications of radiation.
Rogers LR
Continuum (Minneap Minn) 2012 Apr;18(2):343-54. doi: 10.1212/01.CON.0000413662.35174.a8. PMID: 22810131
Post-laminectomy rotokyphoscoliosis causing paraplegia in long term: case report.
Duman I, Guzelkucuk U, Yilmaz B, Tan AK
J Spinal Cord Med 2012 May;35(3):175-7. doi: 10.1179/2045772311Y.0000000052. PMID: 22507027Free PMC Article
Sorafenib plus valproic acid for infant spinal glioblastoma.
Rokes CA, Remke M, Guha-Thakurta N, Witt O, Korshunov A, Pfister S, Wolff JE
J Pediatr Hematol Oncol 2010 Aug;32(6):511-4. doi: 10.1097/MPH.0b013e3181d74702. PMID: 20463608
Progressive vacuolar myelopathy and leukoencephalopathy in childhood acute lymphoblastic leukemia and transient improvement with vitamin B12.
Olcay L, Irkkan C, Senbil N, Uzun H, Basmaci M, Gürer YK
Pediatr Blood Cancer 2007 Oct 15;49(5):754-8. doi: 10.1002/pbc.20720. PMID: 16395685
CNS minimal disease therapy in childhood leukaemia: the place for irradiation.
Eden OB
Br J Cancer 1990 Jul;62(1):6-7. doi: 10.1038/bjc.1990.218. PMID: 2390483Free PMC Article

Prognosis

Preferential sites of metastatic relapse on MRI of initially localized ependymoma in children.
Rootman MS, Konen O, Fried I, Toledano H
Clin Imaging 2017 Jul-Aug;44:12-15. Epub 2017 Mar 30 doi: 10.1016/j.clinimag.2017.03.015. PMID: 28395190
Spinal cord ependymomas in children and adolescents.
Benesch M, Frappaz D, Massimino M
Childs Nerv Syst 2012 Dec;28(12):2017-28. Epub 2012 Sep 8 doi: 10.1007/s00381-012-1908-4. PMID: 22961356
Spinal papillary meningioma: a case report and review of the literature.
Meinsma-vdTuin M, Molenaar WM, Mooij JJ
Acta Neurochir (Wien) 2000;142(6):703-8. doi: 10.1007/s007010070116. PMID: 10949447
More is better! Update of Dana-Farber Cancer Institute/Children's Hospital childhood acute lymphoblastic leukemia trials.
Sallan SE, Gelber RD, Kimball V, Donnelly M, Cohen HJ
Haematol Blood Transfus 1990;33:459-66. doi: 10.1007/978-3-642-74643-7_83. PMID: 2182437
Medulloblastoma in childhood.
Raimondi AJ, Tomita T
Acta Neurochir (Wien) 1979;50(1-2):127-38. doi: 10.1007/BF01813557. PMID: 517184

Clinical prediction guides

In pursuit of prognostic factors in children with pilocytic astrocytomas.
Paixão Becker A, de Oliveira RS, Saggioro FP, Neder L, Chimelli LM, Machado HR
Childs Nerv Syst 2010 Jan;26(1):19-28. Epub 2009 Oct 13 doi: 10.1007/s00381-009-0990-8. PMID: 19823847
Prevalence, clinical pattern, and outcome of CNS involvement in childhood and adolescent non-Hodgkin's lymphoma differ by non-Hodgkin's lymphoma subtype: a Berlin-Frankfurt-Munster Group Report.
Salzburg J, Burkhardt B, Zimmermann M, Wachowski O, Woessmann W, Oschlies I, Klapper W, Wacker HH, Ludwig WD, Niggli F, Mann G, Gadner H, Riehm H, Schrappe M, Reiter A
J Clin Oncol 2007 Sep 1;25(25):3915-22. doi: 10.1200/JCO.2007.11.0700. PMID: 17761975
Surgery and permanent 125I seed paraspinal brachytherapy for malignant tumors with spinal cord compression.
Rogers CL, Theodore N, Dickman CA, Sonntag VK, Thomas T, Lam S, Speiser BL
Int J Radiat Oncol Biol Phys 2002 Oct 1;54(2):505-13. doi: 10.1016/s0360-3016(02)02961-9. PMID: 12243829
Pleuropulmonary blastoma: a clinicopathologic study of 50 cases.
Priest JR, McDermott MB, Bhatia S, Watterson J, Manivel JC, Dehner LP
Cancer 1997 Jul 1;80(1):147-61. PMID: 9210721
PCNU and recurrent childhood brain tumors.
Allen JC, Hancock C, Walker R, Tan C
J Neurooncol 1987;5(3):241-4. doi: 10.1007/BF00151228. PMID: 3681386

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...