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Anaplastic Astroblastoma, MN1-Altered

MedGen UID:
417678
Concept ID:
C2827403
Neoplastic Process
Synonym: Anaplastic Astroblastoma

Definition

An astroblastoma, MN1-altered, characterized by the presence of high mitotic activity, cytologic atypia, and architectural distortion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnaplastic Astroblastoma, MN1-Altered

Professional guidelines

PubMed

Debruyne DN, Dries R, Sengupta S, Seruggia D, Gao Y, Sharma B, Huang H, Moreau L, McLane M, Day DS, Marco E, Chen T, Gray NS, Wong KK, Orkin SH, Yuan GC, Young RA, George RE
Nature 2019 Aug;572(7771):676-680. Epub 2019 Aug 7 doi: 10.1038/s41586-019-1472-0. PMID: 31391581Free PMC Article
Rudà R, Reifenberger G, Frappaz D, Pfister SM, Laprie A, Santarius T, Roth P, Tonn JC, Soffietti R, Weller M, Moyal EC
Neuro Oncol 2018 Mar 27;20(4):445-456. doi: 10.1093/neuonc/nox166. PMID: 29194500Free PMC Article
Hsieh JC, Lesniak MS
Expert Rev Neurother 2005 Nov;5(6 Suppl):S33-9. doi: 10.1586/14737175.5.6.S33. PMID: 16274269

Recent clinical studies

Etiology

Wesseling P, Capper D
Neuropathol Appl Neurobiol 2018 Feb;44(2):139-150. doi: 10.1111/nan.12432. PMID: 28815663
Kamihara J, Bourdeaut F, Foulkes WD, Molenaar JJ, Mossé YP, Nakagawara A, Parareda A, Scollon SR, Schneider KW, Skalet AH, States LJ, Walsh MF, Diller LR, Brodeur GM
Clin Cancer Res 2017 Jul 1;23(13):e98-e106. doi: 10.1158/1078-0432.CCR-17-0652. PMID: 28674118Free PMC Article
Perry A, Wesseling P
Handb Clin Neurol 2016;134:71-95. doi: 10.1016/B978-0-12-802997-8.00005-0. PMID: 26948349
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082
Chowdhary S, Chamberlain MC
Expert Rev Neurother 2006 Apr;6(4):519-32. doi: 10.1586/14737175.6.4.519. PMID: 16623651

Diagnosis

Wang LM, Englander ZK, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:1-30. doi: 10.1007/978-3-031-23705-8_1. PMID: 37452933
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318Free PMC Article
Rudà R, Reifenberger G, Frappaz D, Pfister SM, Laprie A, Santarius T, Roth P, Tonn JC, Soffietti R, Weller M, Moyal EC
Neuro Oncol 2018 Mar 27;20(4):445-456. doi: 10.1093/neuonc/nox166. PMID: 29194500Free PMC Article
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082
Van den Bent MJ, Reni M, Gatta G, Vecht C
Crit Rev Oncol Hematol 2008 Jun;66(3):262-72. Epub 2008 Feb 12 doi: 10.1016/j.critrevonc.2007.11.007. PMID: 18272388

Therapy

Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318Free PMC Article
van den Bent MJ, Tesileanu CMS, Wick W, Sanson M, Brandes AA, Clement PM, Erridge S, Vogelbaum MA, Nowak AK, Baurain JF, Mason WP, Wheeler H, Chinot OL, Gill S, Griffin M, Rogers L, Taal W, Rudà R, Weller M, McBain C, Reijneveld J, Enting RH, Caparrotti F, Lesimple T, Clenton S, Gijtenbeek A, Lim E, Herrlinger U, Hau P, Dhermain F, de Heer I, Aldape K, Jenkins RB, Dubbink HJ, Kros JM, Wesseling P, Nuyens S, Golfinopoulos V, Gorlia T, French P, Baumert BG
Lancet Oncol 2021 Jun;22(6):813-823. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00090-5. PMID: 34000245Free PMC Article
Khan KA, Abbasi AN, Ali N
J Coll Physicians Surg Pak 2014 Dec;24(12):935-9. PMID: 25523732
Jaeckle KA
Semin Oncol 2014 Aug;41(4):468-477. Epub 2014 Jun 30 doi: 10.1053/j.seminoncol.2014.06.009. PMID: 25173140
Van den Bent MJ, Reni M, Gatta G, Vecht C
Crit Rev Oncol Hematol 2008 Jun;66(3):262-72. Epub 2008 Feb 12 doi: 10.1016/j.critrevonc.2007.11.007. PMID: 18272388

Prognosis

Karthigeyan M, Gupta K, Salunke P
J Child Neurol 2017 Jan;32(1):53-59. Epub 2016 Sep 29 doi: 10.1177/0883073816668994. PMID: 27664193
Khan KA, Abbasi AN, Ali N
J Coll Physicians Surg Pak 2014 Dec;24(12):935-9. PMID: 25523732
Fisher JPH, Tweddle DA
Semin Fetal Neonatal Med 2012 Aug;17(4):207-215. Epub 2012 Jun 4 doi: 10.1016/j.siny.2012.05.002. PMID: 22673527
Thom M, Blümcke I, Aronica E
Brain Pathol 2012 May;22(3):350-79. doi: 10.1111/j.1750-3639.2012.00582.x. PMID: 22497610Free PMC Article
Van den Bent MJ, Reni M, Gatta G, Vecht C
Crit Rev Oncol Hematol 2008 Jun;66(3):262-72. Epub 2008 Feb 12 doi: 10.1016/j.critrevonc.2007.11.007. PMID: 18272388

Clinical prediction guides

Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318Free PMC Article
Guillevin R, Herpe G, Verdier M, Guillevin C
Diagn Interv Imaging 2014 Oct;95(10):957-63. Epub 2014 Sep 5 doi: 10.1016/j.diii.2014.07.005. PMID: 25195186
Thom M, Blümcke I, Aronica E
Brain Pathol 2012 May;22(3):350-79. doi: 10.1111/j.1750-3639.2012.00582.x. PMID: 22497610Free PMC Article
Gilbert MR, Ruda R, Soffietti R
Curr Neurol Neurosci Rep 2010 May;10(3):240-7. doi: 10.1007/s11910-010-0109-3. PMID: 20425040
Wang KC, Chi JG, Cho BK
J Korean Med Sci 1993 Apr;8(2):110-6. doi: 10.3346/jkms.1993.8.2.110. PMID: 8397926Free PMC Article

Recent systematic reviews

Bin-Alamer O, Jimenez AE, Azad TD, Bettegowda C, Mukherjee D
World Neurosurg 2022 Sep;165:e251-e264. Epub 2022 Jun 10 doi: 10.1016/j.wneu.2022.06.020. PMID: 35697228
Nieder C, Andratschke NH, Grosu AL
Anticancer Res 2016 Oct;36(10):4985-4995. doi: 10.21873/anticanres.11067. PMID: 27798857
Lecavalier-Barsoum M, Quon H, Abdulkarim B
Cochrane Database Syst Rev 2014 May 15;2014(5):CD007104. doi: 10.1002/14651858.CD007104.pub2. PMID: 24833028Free PMC Article
Deighton RF, McGregor R, Kemp J, McCulloch J, Whittle IR
Brain Pathol 2010 Jul;20(4):691-703. Epub 2010 Jan 13 doi: 10.1111/j.1750-3639.2010.00376.x. PMID: 20175778Free PMC Article
Dinnes J, Cave C, Huang S, Milne R
Br J Cancer 2002 Feb 12;86(4):501-5. doi: 10.1038/sj.bjc.6600135. PMID: 11870527Free PMC Article

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