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Anaplastic Astroblastoma, MN1-Altered

MedGen UID:
417678
Concept ID:
C2827403
Neoplastic Process
Synonym: Anaplastic Astroblastoma

Definition

An astroblastoma, MN1-altered, characterized by the presence of high mitotic activity, cytologic atypia, and architectural distortion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnaplastic Astroblastoma, MN1-Altered

Professional guidelines

PubMed

Antoni D, Feuvret L, Biau J, Robert C, Mazeron JJ, Noël G
Cancer Radiother 2022 Feb-Apr;26(1-2):116-128. Epub 2021 Dec 22 doi: 10.1016/j.canrad.2021.08.006. PMID: 34953698
Valter K, Zhivotovsky B, Gogvadze V
Cell Death Dis 2018 Jan 25;9(2):113. doi: 10.1038/s41419-017-0060-1. PMID: 29371588Free PMC Article
Rudà R, Reifenberger G, Frappaz D, Pfister SM, Laprie A, Santarius T, Roth P, Tonn JC, Soffietti R, Weller M, Moyal EC
Neuro Oncol 2018 Mar 27;20(4):445-456. doi: 10.1093/neuonc/nox166. PMID: 29194500Free PMC Article

Recent clinical studies

Etiology

Bauchet L, Ostrom QT
Neurosurg Clin N Am 2019 Jan;30(1):1-16. doi: 10.1016/j.nec.2018.08.010. PMID: 30470396
Cassia GSE, Alves CAPF, Taranath A, López NS, Oztekin O, Gonçalves FG, Patay Z
Top Magn Reson Imaging 2018 Dec;27(6):479-502. doi: 10.1097/RMR.0000000000000184. PMID: 30516696
Wesseling P, Capper D
Neuropathol Appl Neurobiol 2018 Feb;44(2):139-150. doi: 10.1111/nan.12432. PMID: 28815663
Perry A, Wesseling P
Handb Clin Neurol 2016;134:71-95. doi: 10.1016/B978-0-12-802997-8.00005-0. PMID: 26948349
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082

Diagnosis

Wang LM, Englander ZK, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:1-30. doi: 10.1007/978-3-031-23705-8_1. PMID: 37452933
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318Free PMC Article
Rudà R, Reifenberger G, Frappaz D, Pfister SM, Laprie A, Santarius T, Roth P, Tonn JC, Soffietti R, Weller M, Moyal EC
Neuro Oncol 2018 Mar 27;20(4):445-456. doi: 10.1093/neuonc/nox166. PMID: 29194500Free PMC Article
Wesseling P, Capper D
Neuropathol Appl Neurobiol 2018 Feb;44(2):139-150. doi: 10.1111/nan.12432. PMID: 28815663
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082

Therapy

Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318Free PMC Article
van den Bent MJ, Tesileanu CMS, Wick W, Sanson M, Brandes AA, Clement PM, Erridge S, Vogelbaum MA, Nowak AK, Baurain JF, Mason WP, Wheeler H, Chinot OL, Gill S, Griffin M, Rogers L, Taal W, Rudà R, Weller M, McBain C, Reijneveld J, Enting RH, Caparrotti F, Lesimple T, Clenton S, Gijtenbeek A, Lim E, Herrlinger U, Hau P, Dhermain F, de Heer I, Aldape K, Jenkins RB, Dubbink HJ, Kros JM, Wesseling P, Nuyens S, Golfinopoulos V, Gorlia T, French P, Baumert BG
Lancet Oncol 2021 Jun;22(6):813-823. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00090-5. PMID: 34000245Free PMC Article
Grimm SA, Chamberlain MC
CNS Oncol 2016 Jul;5(3):145-57. Epub 2016 May 27 doi: 10.2217/cns-2016-0002. PMID: 27230974Free PMC Article
Taal W, Bromberg JE, van den Bent MJ
CNS Oncol 2015;4(3):179-92. Epub 2015 Apr 23 doi: 10.2217/cns.15.2. PMID: 25906059Free PMC Article
Jaeckle KA
Semin Oncol 2014 Aug;41(4):468-477. Epub 2014 Jun 30 doi: 10.1053/j.seminoncol.2014.06.009. PMID: 25173140

Prognosis

Appay R, Dehais C, Maurage CA, Alentorn A, Carpentier C, Colin C, Ducray F, Escande F, Idbaih A, Kamoun A, Marie Y, Mokhtari K, Tabouret E, Trabelsi N, Uro-Coste E, Delattre JY, Figarella-Branger D; POLA Network
Neuro Oncol 2019 Dec 17;21(12):1519-1528. doi: 10.1093/neuonc/noz124. PMID: 31832685Free PMC Article
Irwin MS, Park JR
Pediatr Clin North Am 2015 Feb;62(1):225-56. doi: 10.1016/j.pcl.2014.09.015. PMID: 25435121
Fisher JPH, Tweddle DA
Semin Fetal Neonatal Med 2012 Aug;17(4):207-215. Epub 2012 Jun 4 doi: 10.1016/j.siny.2012.05.002. PMID: 22673527
Thom M, Blümcke I, Aronica E
Brain Pathol 2012 May;22(3):350-79. doi: 10.1111/j.1750-3639.2012.00582.x. PMID: 22497610Free PMC Article
Van den Bent MJ, Reni M, Gatta G, Vecht C
Crit Rev Oncol Hematol 2008 Jun;66(3):262-72. Epub 2008 Feb 12 doi: 10.1016/j.critrevonc.2007.11.007. PMID: 18272388

Clinical prediction guides

Qadir MI, Ahmed B, Noreen S
Crit Rev Eukaryot Gene Expr 2024;34(2):1-13. doi: 10.1615/CritRevEukaryotGeneExpr.2023049559. PMID: 38073438
Umemura Y, Orringer D, Junck L, Varela ML, West MEJ, Faisal SM, Comba A, Heth J, Sagher O, Leung D, Mammoser A, Hervey-Jumper S, Zamler D, Yadav VN, Dunn P, Al-Holou W, Hollon T, Kim MM, Wahl DR, Camelo-Piragua S, Lieberman AP, Venneti S, McKeever P, Lawrence T, Kurokawa R, Sagher K, Altshuler D, Zhao L, Muraszko K, Castro MG, Lowenstein PR
Lancet Oncol 2023 Sep;24(9):1042-1052. doi: 10.1016/S1470-2045(23)00347-9. PMID: 37657463
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318Free PMC Article
van den Bent MJ, Smits M, Kros JM, Chang SM
J Clin Oncol 2017 Jul 20;35(21):2394-2401. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.72.6737. PMID: 28640702
Thom M, Blümcke I, Aronica E
Brain Pathol 2012 May;22(3):350-79. doi: 10.1111/j.1750-3639.2012.00582.x. PMID: 22497610Free PMC Article

Recent systematic reviews

Bin-Alamer O, Jimenez AE, Azad TD, Bettegowda C, Mukherjee D
World Neurosurg 2022 Sep;165:e251-e264. Epub 2022 Jun 10 doi: 10.1016/j.wneu.2022.06.020. PMID: 35697228
Nieder C, Andratschke NH, Grosu AL
Anticancer Res 2016 Oct;36(10):4985-4995. doi: 10.21873/anticanres.11067. PMID: 27798857
Lecavalier-Barsoum M, Quon H, Abdulkarim B
Cochrane Database Syst Rev 2014 May 15;2014(5):CD007104. doi: 10.1002/14651858.CD007104.pub2. PMID: 24833028Free PMC Article
Deighton RF, McGregor R, Kemp J, McCulloch J, Whittle IR
Brain Pathol 2010 Jul;20(4):691-703. Epub 2010 Jan 13 doi: 10.1111/j.1750-3639.2010.00376.x. PMID: 20175778Free PMC Article
Seo HS, Kim JH, Lee DH, Lee YH, Suh SI, Kim SY, Na DG
AJNR Am J Neuroradiol 2010 Mar;31(3):498-503. Epub 2009 Oct 29 doi: 10.3174/ajnr.A1864. PMID: 19875469Free PMC Article

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