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Herpangina

MedGen UID:
42435
Concept ID:
C0019338
Disease or Syndrome
Synonym: Herpanginas
SNOMED CT: Herpangina (186659004); Enteroviral vesicular pharyngitis (186659004); Vesicular pharyngitis (274102007)
 
Monarch Initiative: MONDO:0005791

Definition

A viral infectious disease that results in infection located in mouth, has material basis in Human coxsackievirus A16, has material basis in Human enterovirus 71, has material basis in group B coxsackievirus, or has material basis in echoviruses, which are transmitted by ingestion of food contaminated with feces, transmitted by contact with pharyngeal secretions, or transmitted by droplet spread of oronasal secretions. The infection has symptom fever, has symptom sore throat, and has symptom lesions in the back area of the mouth, particularly the soft palate or tonsillar pillars. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHerpangina

Professional guidelines

PubMed

Song Y, Wang D, Zhang Y, Han Z, Xiao J, Lu H, Yan D, Ji T, Yang Q, Zhu S, Xu W
Viruses 2020 Sep 23;12(10) doi: 10.3390/v12101061. PMID: 32977444Free PMC Article
Yu H, Li XW, Liu QB, Deng HL, Liu G, Jiang RM, Deng JK, Ye YZ, Hao JH, Chen YH, Nong GM, Shen ZB, Liu CS, Zou YX, Wu JZ, Wu XD, Chen BQ, Luo RP, Lin AW, Chen Y, Liu XD
World J Pediatr 2020 Apr;16(2):129-134. Epub 2019 Jul 25 doi: 10.1007/s12519-019-00277-9. PMID: 31347021
Andrés C, Guasch E, Piñana M, Fernandes P, Gimferrer L, Esso DV, Codina MG, Esperalba J, Vila J, Rodrigo C, Martín MC, Fuentes F, Rubio S, Pumarola T; Group for EV Surveillance in Pediatric Primary Care, Antón A
Future Microbiol 2019 Apr;14:499-507. Epub 2019 Apr 29 doi: 10.2217/fmb-2018-0336. PMID: 31033351

Recent clinical studies

Etiology

Yu H, Li XW, Liu QB, Deng HL, Liu G, Jiang RM, Deng JK, Ye YZ, Hao JH, Chen YH, Nong GM, Shen ZB, Liu CS, Zou YX, Wu JZ, Wu XD, Chen BQ, Luo RP, Lin AW, Chen Y, Liu XD
World J Pediatr 2020 Apr;16(2):129-134. Epub 2019 Jul 25 doi: 10.1007/s12519-019-00277-9. PMID: 31347021
Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H
J Periodontol 2018 Jun;89 Suppl 1:S74-S84. doi: 10.1002/JPER.17-0719. PMID: 29926944
Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H
J Clin Periodontol 2018 Jun;45 Suppl 20:S68-S77. doi: 10.1111/jcpe.12940. PMID: 29926499
Park K, Lee B, Baek K, Cheon D, Yeo S, Park J, Soh J, Cheon H, Yoon K, Choi Y
Virol J 2012 Sep 17;9:205. doi: 10.1186/1743-422X-9-205. PMID: 22985487Free PMC Article
Ruan F, Yang T, Ma H, Jin Y, Song S, Fontaine RE, Zhu BP
Pediatrics 2011 Apr;127(4):e898-904. Epub 2011 Mar 21 doi: 10.1542/peds.2010-1497. PMID: 21422083

Diagnosis

Chiu ML, Luo ST, Chen YY, Chung WY, Duong V, Dussart P, Chan YF, Perera D, Ooi MH, Thao NTT, Truong HK, Lee MS
Vaccine 2020 Jan 3;38(1):1-9. Epub 2019 Oct 31 doi: 10.1016/j.vaccine.2019.09.111. PMID: 31679864
Yu H, Li XW, Liu QB, Deng HL, Liu G, Jiang RM, Deng JK, Ye YZ, Hao JH, Chen YH, Nong GM, Shen ZB, Liu CS, Zou YX, Wu JZ, Wu XD, Chen BQ, Luo RP, Lin AW, Chen Y, Liu XD
World J Pediatr 2020 Apr;16(2):129-134. Epub 2019 Jul 25 doi: 10.1007/s12519-019-00277-9. PMID: 31347021
Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H
J Periodontol 2018 Jun;89 Suppl 1:S74-S84. doi: 10.1002/JPER.17-0719. PMID: 29926944
Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H
J Clin Periodontol 2018 Jun;45 Suppl 20:S68-S77. doi: 10.1111/jcpe.12940. PMID: 29926499
Scott LA, Stone MS
Dermatol Online J 2003 Aug;9(3):4. PMID: 12952751

Therapy

Chiu ML, Luo ST, Chen YY, Chung WY, Duong V, Dussart P, Chan YF, Perera D, Ooi MH, Thao NTT, Truong HK, Lee MS
Vaccine 2020 Jan 3;38(1):1-9. Epub 2019 Oct 31 doi: 10.1016/j.vaccine.2019.09.111. PMID: 31679864
Lin JY, Kung YA, Shih SR
J Biomed Sci 2019 Sep 3;26(1):65. doi: 10.1186/s12929-019-0560-7. PMID: 31481071Free PMC Article
Yao X, Bian LL, Lu WW, Li JX, Mao QY, Wang YP, Gao F, Wu X, Ye Q, Li XL, Zhu FC, Liang Z
Hum Vaccin Immunother 2017 Apr 3;13(4):823-830. Epub 2016 Oct 21 doi: 10.1080/21645515.2016.1236879. PMID: 27768527Free PMC Article
Abzug MJ
J Infect 2014 Jan;68 Suppl 1:S108-14. Epub 2013 Oct 8 doi: 10.1016/j.jinf.2013.09.020. PMID: 24119825
Wang SM, Lei HY, Liu CC
Clin Dev Immunol 2012;2012:876241. Epub 2012 Aug 23 doi: 10.1155/2012/876241. PMID: 22956971Free PMC Article

Prognosis

Ibba R, Carta A, Madeddu S, Caria P, Serreli G, Piras S, Sestito S, Loddo R, Sanna G
Viruses 2021 Jan 4;13(1) doi: 10.3390/v13010058. PMID: 33406781Free PMC Article
Yu H, Li XW, Liu QB, Deng HL, Liu G, Jiang RM, Deng JK, Ye YZ, Hao JH, Chen YH, Nong GM, Shen ZB, Liu CS, Zou YX, Wu JZ, Wu XD, Chen BQ, Luo RP, Lin AW, Chen Y, Liu XD
World J Pediatr 2020 Apr;16(2):129-134. Epub 2019 Jul 25 doi: 10.1007/s12519-019-00277-9. PMID: 31347021
Yang TO, Arthur Huang KY, Chen MH, Chen PC, Huang WT
Pediatr Infect Dis J 2019 Sep;38(9):887-893. doi: 10.1097/INF.0000000000002351. PMID: 31033911
Yang TO, Huang WT, Chen MH, Chen PC
Epidemiol Infect 2016 May;144(7):1512-9. Epub 2015 Nov 23 doi: 10.1017/S0950268815002988. PMID: 26593706Free PMC Article
Ruan F, Yang T, Ma H, Jin Y, Song S, Fontaine RE, Zhu BP
Pediatrics 2011 Apr;127(4):e898-904. Epub 2011 Mar 21 doi: 10.1542/peds.2010-1497. PMID: 21422083

Clinical prediction guides

Ibba R, Carta A, Madeddu S, Caria P, Serreli G, Piras S, Sestito S, Loddo R, Sanna G
Viruses 2021 Jan 4;13(1) doi: 10.3390/v13010058. PMID: 33406781Free PMC Article
Yang TO, Arthur Huang KY, Chen MH, Chen PC, Huang WT
Pediatr Infect Dis J 2019 Sep;38(9):887-893. doi: 10.1097/INF.0000000000002351. PMID: 31033911
Yang TO, Huang WT, Chen MH, Chen PC
Epidemiol Infect 2016 May;144(7):1512-9. Epub 2015 Nov 23 doi: 10.1017/S0950268815002988. PMID: 26593706Free PMC Article
Ruan F, Yang T, Ma H, Jin Y, Song S, Fontaine RE, Zhu BP
Pediatrics 2011 Apr;127(4):e898-904. Epub 2011 Mar 21 doi: 10.1542/peds.2010-1497. PMID: 21422083
Lee TC, Guo HR, Su HJ, Yang YC, Chang HL, Chen KT
Pediatr Infect Dis J 2009 Oct;28(10):904-10. doi: 10.1097/INF.0b013e3181a41d63. PMID: 20118685

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