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Epidemic keratoconjunctivitis

MedGen UID:
4500
Concept ID:
C0014493
Disease or Syndrome
Synonyms: EKC; EKC - epidemic keratoconjunctivitis; Epidemic Keratoconjunctivitis; epidemic keratoconjunctivitis; Shipyard eye; shipyard eye; Virus keratoconjunctivitis
SNOMED CT: Epidemic keratoconjunctivitis (60548004); Shipyard eye (60548004); Virus keratoconjunctivitis (60548004); EKC - epidemic keratoconjunctivitis (60548004)
 
Monarch Initiative: MONDO:0001615

Definition

Keratoconjunctivitis resulting from infection by adenoviruses. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpidemic keratoconjunctivitis

Professional guidelines

PubMed

Liu SH, Hawkins BS, Ren M, Ng SM, Leslie L, Han G, Kuo IC
Am J Ophthalmol 2022 Aug;240:265-275. Epub 2022 Mar 22 doi: 10.1016/j.ajo.2022.03.018. PMID: 35331686Free PMC Article
Martin C, Löw U, Quintin A, Schießl G, Gärtner B, Heim A, Seitz B
Graefes Arch Clin Exp Ophthalmol 2022 Jan;260(1):173-180. Epub 2021 Aug 18 doi: 10.1007/s00417-021-05344-4. PMID: 34406500Free PMC Article
Gonzalez G, Yawata N, Aoki K, Kitaichi N
J Clin Virol 2019 Mar;112:1-9. Epub 2019 Jan 11 doi: 10.1016/j.jcv.2019.01.004. PMID: 30654207

Recent clinical studies

Etiology

Philip AM, Fernandez-Santos CC, Ramezani K, Dolinko AH, Manhapra A, Look-Why S, Chang PY, Foster CS, Anesi SD
Cornea 2023 Mar 1;42(3):280-283. Epub 2022 Aug 24 doi: 10.1097/ICO.0000000000003056. PMID: 36036657
Liu SH, Hawkins BS, Ren M, Ng SM, Leslie L, Han G, Kuo IC
Am J Ophthalmol 2022 Aug;240:265-275. Epub 2022 Mar 22 doi: 10.1016/j.ajo.2022.03.018. PMID: 35331686Free PMC Article
Liu SH, Hawkins BS, Ng SM, Ren M, Leslie L, Han G, Kuo IC
Cochrane Database Syst Rev 2022 Mar 3;3(3):CD013520. doi: 10.1002/14651858.CD013520.pub2. PMID: 35238405Free PMC Article
Martin C, Löw U, Quintin A, Schießl G, Gärtner B, Heim A, Seitz B
Graefes Arch Clin Exp Ophthalmol 2022 Jan;260(1):173-180. Epub 2021 Aug 18 doi: 10.1007/s00417-021-05344-4. PMID: 34406500Free PMC Article
Parikh SR, Parikh RS
Indian J Ophthalmol 2021 Mar;69(3):510-516. doi: 10.4103/ijo.IJO_1549_20. PMID: 33595464Free PMC Article

Diagnosis

Liu SH, Hawkins BS, Ng SM, Ren M, Leslie L, Han G, Kuo IC
Cochrane Database Syst Rev 2022 Mar 3;3(3):CD013520. doi: 10.1002/14651858.CD013520.pub2. PMID: 35238405Free PMC Article
Rajaiya J, Saha A, Ismail AM, Zhou X, Su T, Chodosh J
Viruses 2021 Feb 13;13(2) doi: 10.3390/v13020293. PMID: 33668417Free PMC Article
Jonas RA, Ung L, Rajaiya J, Chodosh J
Prog Retin Eye Res 2020 May;76:100826. Epub 2019 Dec 28 doi: 10.1016/j.preteyeres.2019.100826. PMID: 31891773Free PMC Article
Jhanji V, Chan TC, Li EY, Agarwal K, Vajpayee RB
Surv Ophthalmol 2015 Sep-Oct;60(5):435-43. Epub 2015 May 5 doi: 10.1016/j.survophthal.2015.04.001. PMID: 26077630
González-López JJ, Morcillo-Laiz R, Muñoz-Negrete FJ
Arch Soc Esp Oftalmol 2013 Mar;88(3):108-15. Epub 2012 Sep 25 doi: 10.1016/j.oftal.2012.07.007. PMID: 23473088

Therapy

Liu SH, Hawkins BS, Ren M, Ng SM, Leslie L, Han G, Kuo IC
Am J Ophthalmol 2022 Aug;240:265-275. Epub 2022 Mar 22 doi: 10.1016/j.ajo.2022.03.018. PMID: 35331686Free PMC Article
Liu SH, Hawkins BS, Ng SM, Ren M, Leslie L, Han G, Kuo IC
Cochrane Database Syst Rev 2022 Mar 3;3(3):CD013520. doi: 10.1002/14651858.CD013520.pub2. PMID: 35238405Free PMC Article
Meyer-Rüsenberg B, Loderstädt U, Richard G, Kaulfers PM, Gesser C
Dtsch Arztebl Int 2011 Jul;108(27):475-80. Epub 2011 Jul 8 doi: 10.3238/arztebl.2011.0475. PMID: 21814523Free PMC Article
Kinchington PR, Romanowski EG, Jerold Gordon Y
J Antimicrob Chemother 2005 Apr;55(4):424-9. Epub 2005 Mar 2 doi: 10.1093/jac/dki057. PMID: 15743895
Murrah WF
Ann Ophthalmol 1988 Jan;20(1):36-8. PMID: 2830832

Prognosis

Liu SH, Hawkins BS, Ng SM, Ren M, Leslie L, Han G, Kuo IC
Cochrane Database Syst Rev 2022 Mar 3;3(3):CD013520. doi: 10.1002/14651858.CD013520.pub2. PMID: 35238405Free PMC Article
Kiyat P, Palamar M, Yilmaz SG, Emre S
Eur J Ophthalmol 2020 Sep;30(5):897-900. Epub 2019 May 21 doi: 10.1177/1120672119851475. PMID: 31111724
Garcia-Zalisnak D, Rapuano C, Sheppard JD, Davis AR
Eye Contact Lens 2018 Sep;44 Suppl 1:S1-S7. doi: 10.1097/ICL.0000000000000226. PMID: 29664772
Meyer-Rüsenberg B, Loderstädt U, Richard G, Kaulfers PM, Gesser C
Dtsch Arztebl Int 2011 Jul;108(27):475-80. Epub 2011 Jul 8 doi: 10.3238/arztebl.2011.0475. PMID: 21814523Free PMC Article
Murrah WF
Ann Ophthalmol 1988 Jan;20(1):36-8. PMID: 2830832

Clinical prediction guides

Ruhlandt M, Becker B, Paulmann D, Dotzauer A, Arndt A, Todt D, Steinmann E, Steinmann J, Brill FH
Am J Infect Control 2023 Sep;51(9):1011-1016. Epub 2023 Feb 2 doi: 10.1016/j.ajic.2023.01.014. PMID: 36736900
Abbas AA, Lian RR, Afshari NA
Curr Opin Ophthalmol 2020 Jan;31(1):28-32. doi: 10.1097/ICU.0000000000000630. PMID: 31770164
Kiyat P, Palamar M, Yilmaz SG, Emre S
Eur J Ophthalmol 2020 Sep;30(5):897-900. Epub 2019 May 21 doi: 10.1177/1120672119851475. PMID: 31111724
Zhou X, Ramke M, Chintakuntlawar AV, Lee JY, Rajaiya J, Chodosh J
Immunol Cell Biol 2017 Jan;95(1):108-116. Epub 2016 Aug 16 doi: 10.1038/icb.2016.73. PMID: 27528076Free PMC Article
Adhikary AK, Banik U
J Clin Virol 2014 Dec;61(4):477-86. Epub 2014 Nov 4 doi: 10.1016/j.jcv.2014.10.015. PMID: 25464969

Recent systematic reviews

Liu P, Li G, Han M, Cheng X, Cui Y, Md, Yang Q, Md, Zhang C
Ther Innov Regul Sci 2023 May;57(3):476-483. Epub 2022 Nov 22 doi: 10.1007/s43441-022-00479-w. PMID: 36414914
Liu SH, Hawkins BS, Ren M, Ng SM, Leslie L, Han G, Kuo IC
Am J Ophthalmol 2022 Aug;240:265-275. Epub 2022 Mar 22 doi: 10.1016/j.ajo.2022.03.018. PMID: 35331686Free PMC Article
Liu SH, Hawkins BS, Ng SM, Ren M, Leslie L, Han G, Kuo IC
Cochrane Database Syst Rev 2022 Mar 3;3(3):CD013520. doi: 10.1002/14651858.CD013520.pub2. PMID: 35238405Free PMC Article
Omar Akhtar A, Singh H, Si F, Hodge WG
Can J Ophthalmol 2014 Aug;49(4):345-50. doi: 10.1016/j.jcjo.2014.04.003. PMID: 25103651

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