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Persecutory Type Delusional Disorder

MedGen UID:
452809
•Concept ID:
C0948981
•
Mental or Behavioral Dysfunction

Definition

A subtype of delusional disorder characterized by the central delusional theme that the individual is being malevolently treated (for example, maligned, harassed, conspired against, poisoned or drugged) by another person or group. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPersecutory Type Delusional Disorder

Recent clinical studies

Etiology

Homicides committed by delusional patients in the early 20th and 21st centuries: A study conducted in a French secure unit.
Provoost E, Raymond S, Gasman I
J Forensic Sci 2022 Jan;67(1):265-274. Epub 2021 Oct 11 doi: 10.1111/1556-4029.14892. PMID: 34634145
An Australian study of delusional disorder in late life.
Nagendra J, Snowdon J
Int Psychogeriatr 2020 Apr;32(4):453-462. Epub 2019 Jul 29 doi: 10.1017/S1041610219000966. PMID: 31354123
De Clérambault Syndrome, Othello Syndrome, Folie à Deux and Variants.
Delgado MG, Bogousslavsky J
Front Neurol Neurosci 2018;42:44-50. Epub 2017 Nov 17 doi: 10.1159/000475685. PMID: 29151090
Typologies of positive psychotic symptoms in methamphetamine dependence.
Bousman CA, McKetin R, Burns R, Woods SP, Morgan EE, Atkinson JH, Everall IP, Grant I; Translational Methamphetamine AIDS Research Center (TMARC) Group
Am J Addict 2015 Mar;24(2):94-97. doi: 10.1111/ajad.12160. PMID: 25864598Free PMC Article
Delusional disorder: retrospective analysis of 86 Chinese outpatients.
Hsiao MC, Liu CY, Yang YY, Yeh EK
Psychiatry Clin Neurosci 1999 Dec;53(6):673-6. doi: 10.1046/j.1440-1819.1999.00624.x. PMID: 10687749

Diagnosis

Domestic Mass Shooters: The Association With Unmedicated and Untreated Psychiatric Illness.
Glick ID, Cerfolio NE, Kamis D, Laurence M
J Clin Psychopharmacol 2021 Jul-Aug 01;41(4):366-369. doi: 10.1097/JCP.0000000000001417. PMID: 34102649
De Clérambault Syndrome, Othello Syndrome, Folie à Deux and Variants.
Delgado MG, Bogousslavsky J
Front Neurol Neurosci 2018;42:44-50. Epub 2017 Nov 17 doi: 10.1159/000475685. PMID: 29151090
Typologies of positive psychotic symptoms in methamphetamine dependence.
Bousman CA, McKetin R, Burns R, Woods SP, Morgan EE, Atkinson JH, Everall IP, Grant I; Translational Methamphetamine AIDS Research Center (TMARC) Group
Am J Addict 2015 Mar;24(2):94-97. doi: 10.1111/ajad.12160. PMID: 25864598Free PMC Article
Age at onset of delusional disorder is dependent on the delusional theme.
Yamada N, Nakajima S, Noguchi T
Acta Psychiatr Scand 1998 Feb;97(2):122-4. doi: 10.1111/j.1600-0447.1998.tb09973.x. PMID: 9517905
Delusional disorder: the recognition and management of paranoia.
Manschreck TC
J Clin Psychiatry 1996;57 Suppl 3:32-8; discussion 49. PMID: 8626368

Therapy

Domestic Mass Shooters: The Association With Unmedicated and Untreated Psychiatric Illness.
Glick ID, Cerfolio NE, Kamis D, Laurence M
J Clin Psychopharmacol 2021 Jul-Aug 01;41(4):366-369. doi: 10.1097/JCP.0000000000001417. PMID: 34102649
An Australian study of delusional disorder in late life.
Nagendra J, Snowdon J
Int Psychogeriatr 2020 Apr;32(4):453-462. Epub 2019 Jul 29 doi: 10.1017/S1041610219000966. PMID: 31354123
Typologies of positive psychotic symptoms in methamphetamine dependence.
Bousman CA, McKetin R, Burns R, Woods SP, Morgan EE, Atkinson JH, Everall IP, Grant I; Translational Methamphetamine AIDS Research Center (TMARC) Group
Am J Addict 2015 Mar;24(2):94-97. doi: 10.1111/ajad.12160. PMID: 25864598Free PMC Article
Delusional disorder: retrospective analysis of 86 Chinese outpatients.
Hsiao MC, Liu CY, Yang YY, Yeh EK
Psychiatry Clin Neurosci 1999 Dec;53(6):673-6. doi: 10.1046/j.1440-1819.1999.00624.x. PMID: 10687749
Delusional disorder: the recognition and management of paranoia.
Manschreck TC
J Clin Psychiatry 1996;57 Suppl 3:32-8; discussion 49. PMID: 8626368

Prognosis

The description of the litigious querulant: Heinrich von Kleist's Novella Michael Kohlhaas.
Gerevich J, Ungvari GS
Psychopathology 2015;48(2):79-83. Epub 2014 Oct 29 doi: 10.1159/000366562. PMID: 25358386
Clinical presentation and early care relationships in 'poor-me' and 'bad-me' paranoia.
Morris E, Milner P, Trower P, Peters E
Br J Clin Psychol 2011 Jun;50(2):211-6. Epub 2011 Mar 2 doi: 10.1348/014466510X525498. PMID: 21545452
What makes one person paranoid and another person anxious? The differential prediction of social anxiety and persecutory ideation in an experimental situation.
Freeman D, Gittins M, Pugh K, Antley A, Slater M, Dunn G
Psychol Med 2008 Aug;38(8):1121-32. Epub 2008 Jun 4 doi: 10.1017/S0033291708003589. PMID: 18533055Free PMC Article
Delusional disorder: the recognition and management of paranoia.
Manschreck TC
J Clin Psychiatry 1996;57 Suppl 3:32-8; discussion 49. PMID: 8626368
Paranoid schizophrenia: prognosis under DSM-II and DSM-III-R.
Goodman AB
Compr Psychiatry 1989 May-Jun;30(3):259-66. doi: 10.1016/0010-440x(89)90047-3. PMID: 2731425

Clinical prediction guides

Homicides committed by delusional patients in the early 20th and 21st centuries: A study conducted in a French secure unit.
Provoost E, Raymond S, Gasman I
J Forensic Sci 2022 Jan;67(1):265-274. Epub 2021 Oct 11 doi: 10.1111/1556-4029.14892. PMID: 34634145
Domestic Mass Shooters: The Association With Unmedicated and Untreated Psychiatric Illness.
Glick ID, Cerfolio NE, Kamis D, Laurence M
J Clin Psychopharmacol 2021 Jul-Aug 01;41(4):366-369. doi: 10.1097/JCP.0000000000001417. PMID: 34102649
Typologies of positive psychotic symptoms in methamphetamine dependence.
Bousman CA, McKetin R, Burns R, Woods SP, Morgan EE, Atkinson JH, Everall IP, Grant I; Translational Methamphetamine AIDS Research Center (TMARC) Group
Am J Addict 2015 Mar;24(2):94-97. doi: 10.1111/ajad.12160. PMID: 25864598Free PMC Article
First presentation psychosis among the elderly in Singapore.
Tan LL, Seng KH
Singapore Med J 2012 Jul;53(7):463-7. PMID: 22815015
Clinical presentation and early care relationships in 'poor-me' and 'bad-me' paranoia.
Morris E, Milner P, Trower P, Peters E
Br J Clin Psychol 2011 Jun;50(2):211-6. Epub 2011 Mar 2 doi: 10.1348/014466510X525498. PMID: 21545452

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