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Pituicytoma

MedGen UID:
458776
Concept ID:
C2986550
Neoplastic Process
Synonyms: pituicytoma; Pituicytoma (WHO Grade 1); Pituicytoma (WHO Grade I); pituicytoma (WHO grade I); Posterior Pituitary Astrocytoma; posterior pituitary astrocytoma; PTCY
SNOMED CT: Pituicytoma (450901008); Pituicytoma (608817003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
HPO: HP:0011754
Monarch Initiative: MONDO:0006372
Orphanet: ORPHA251623

Definition

A solid, low grade, spindle cell, glial neoplasm of adults that originates in the neurohypophysis or infundibulum. Clinical signs and symptoms include visual disturbance, headache and features of hypopituitarism. Pituicytomas are well-circumscribed, solid masses that can measure up to several centimeters. Histologically, they show a compact architecture consisting of elongate, bipolar spindle cells arranged in interlacing fascicles or assuming a storiform pattern. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPituicytoma
Follow this link to review classifications for Pituicytoma in Orphanet.

Professional guidelines

PubMed

Trifa A, Knafo S, Maatoug A, Militaru M, Copaciu R, Aghakhani N, Parker F
Acta Neurol Belg 2023 Jun;123(3):815-822. Epub 2022 Mar 17 doi: 10.1007/s13760-022-01917-0. PMID: 35301693
Zoli M, Guaraldi F, Zoia C, La Corte E, Asioli S, Bongetta D, Rustici A, Mazzatenta D
Pituitary 2021 Apr;24(2):269-283. Epub 2020 Nov 17 doi: 10.1007/s11102-020-01107-2. PMID: 33200305Free PMC Article
Wang J, Liu Z, Du J, Cui Y, Fang J, Xu L, Li G
Neuropathology 2016 Oct;36(5):432-440. Epub 2016 Feb 26 doi: 10.1111/neup.12291. PMID: 26919073

Recent clinical studies

Etiology

Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Cheng ML, Zhao J, Lin Y, Qiu HS
Neuro Endocrinol Lett 2021 Nov 30;42(7):425-432. PMID: 34847317
Wei LD, Li C, Li D, Liu XJ, Li RT, Li LW, Wang JM, Zhou DB
Pituitary 2021 Oct;24(5):754-767. Epub 2021 May 12 doi: 10.1007/s11102-021-01152-5. PMID: 33982223Free PMC Article
Ellis JA, Tsankova NM, D'Amico R, Ausiello JC, Canoll P, Rosenblum MK, Bruce JN
World Neurosurg 2012 Jul;78(1-2):191.E1-7. Epub 2011 Nov 7 doi: 10.1016/j.wneu.2011.09.011. PMID: 22120271Free PMC Article
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P
Acta Neuropathol 2007 Aug;114(2):97-109. Epub 2007 Jul 6 doi: 10.1007/s00401-007-0243-4. PMID: 17618441Free PMC Article

Diagnosis

Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Wei LD, Li C, Li D, Liu XJ, Li RT, Li LW, Wang JM, Zhou DB
Pituitary 2021 Oct;24(5):754-767. Epub 2021 May 12 doi: 10.1007/s11102-021-01152-5. PMID: 33982223Free PMC Article
Schwetye KE, Dahiya SM
Surg Pathol Clin 2020 Jun;13(2):305-329. doi: 10.1016/j.path.2020.02.006. PMID: 32389269
Salge-Arrieta FJ, Carrasco-Moro R, Rodríguez-Berrocal V, Pian H, Martínez-San Millán JS, Iglesias P, Ley-Urzáiz L
J Endocrinol Invest 2019 Apr;42(4):371-384. Epub 2018 Jul 20 doi: 10.1007/s40618-018-0923-z. PMID: 30030746
Ellis JA, Tsankova NM, D'Amico R, Ausiello JC, Canoll P, Rosenblum MK, Bruce JN
World Neurosurg 2012 Jul;78(1-2):191.E1-7. Epub 2011 Nov 7 doi: 10.1016/j.wneu.2011.09.011. PMID: 22120271Free PMC Article

Therapy

Viaene AN, Lee EB, Nasrallah MP
Diagn Cytopathol 2020 Apr;48(4):342-349. Epub 2019 Dec 28 doi: 10.1002/dc.24372. PMID: 31883319
Sollfrank L, Lettmaier S, Erdmann M, Uslu U
Anticancer Res 2019 Jul;39(7):3955-3959. doi: 10.21873/anticanres.13549. PMID: 31262927
Amano K, Aihara Y, Tsuzuki S, Okada Y, Kawamata T
Acta Neurochir (Wien) 2019 Apr;161(4):695-706. Epub 2019 Feb 14 doi: 10.1007/s00701-018-03778-0. PMID: 30762125
Guerrero-Pérez F, Vidal N, Marengo AP, Pozo CD, Blanco C, Rivero-Celada D, Díez JJ, Iglesias P, Picó A, Villabona C
Endocrine 2019 Jan;63(1):36-43. Epub 2018 Oct 1 doi: 10.1007/s12020-018-1774-2. PMID: 30276594
Ida CM, Yan X, Jentoft ME, Kip NS, Scheithauer BW, Morris JM, Dogan A, Parisi JE, Kovacs K
Endocr Pathol 2013 Sep;24(3):149-55. doi: 10.1007/s12022-013-9254-y. PMID: 23817895

Prognosis

Pruis IJ, Verburg FA, Balvers RK, Harteveld AA, Feelders RA, Vernooij MW, Smits M, Neggers SJCMM, Veldhuijzen van Zanten SEM
J Nucl Med 2024 May 1;65(5):688-692. doi: 10.2967/jnumed.123.266853. PMID: 38514085
Wei LD, Li C, Li D, Liu XJ, Li RT, Li LW, Wang JM, Zhou DB
Pituitary 2021 Oct;24(5):754-767. Epub 2021 May 12 doi: 10.1007/s11102-021-01152-5. PMID: 33982223Free PMC Article
Asa SL, Mete O, Ezzat S
Endocr Pathol 2021 Mar;32(1):3-16. Epub 2021 Jan 12 doi: 10.1007/s12022-021-09663-4. PMID: 33433883
Guo X, Fu H, Kong X, Gao L, Wang W, Ma W, Yao Y, Wang R, Xing B
Medicine (Baltimore) 2016 Mar;95(10):e3062. doi: 10.1097/MD.0000000000003062. PMID: 26962837Free PMC Article
Ellis JA, Tsankova NM, D'Amico R, Ausiello JC, Canoll P, Rosenblum MK, Bruce JN
World Neurosurg 2012 Jul;78(1-2):191.E1-7. Epub 2011 Nov 7 doi: 10.1016/j.wneu.2011.09.011. PMID: 22120271Free PMC Article

Clinical prediction guides

Pruis IJ, Verburg FA, Balvers RK, Harteveld AA, Feelders RA, Vernooij MW, Smits M, Neggers SJCMM, Veldhuijzen van Zanten SEM
J Nucl Med 2024 May 1;65(5):688-692. doi: 10.2967/jnumed.123.266853. PMID: 38514085
Kim H, Lee K, Shim YM, Kim EE, Kim SK, Phi JH, Park CK, Choi SH, Park SH
Lab Invest 2023 Aug;103(8):100159. Epub 2023 Apr 22 doi: 10.1016/j.labinv.2023.100159. PMID: 37088465
Teti C, Castelletti L, Allegretti L, Talco M, Zona G, Minuto F, Boschetti M, Ferone D
Pituitary 2015 Oct;18(5):592-7. doi: 10.1007/s11102-014-0612-7. PMID: 25311104
Grote A, Kovacs A, Clusmann H, Becker AJ, Niehusmann P
Clin Neuropathol 2010 May-Jun;29(3):127-33. doi: 10.5414/npp29127. PMID: 20423685
Kowalski RJ, Prayson RA, Mayberg MR
Ann Diagn Pathol 2004 Oct;8(5):290-4. doi: 10.1016/j.anndiagpath.2004.07.006. PMID: 15494936

Recent systematic reviews

Zoli M, Guaraldi F, Zoia C, La Corte E, Asioli S, Bongetta D, Rustici A, Mazzatenta D
Pituitary 2021 Apr;24(2):269-283. Epub 2020 Nov 17 doi: 10.1007/s11102-020-01107-2. PMID: 33200305Free PMC Article
Whipple SG, Savardekar AR, Rao S, Mahadevan A, Guthikonda B, Kosty JA
World Neurosurg 2021 Jan;145:148-158. Epub 2020 Sep 8 doi: 10.1016/j.wneu.2020.09.023. PMID: 32916355
Guerrero-Pérez F, Marengo AP, Vidal N, Iglesias P, Villabona C
Rev Endocr Metab Disord 2019 Jun;20(2):219-238. doi: 10.1007/s11154-019-09484-1. PMID: 30864049

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