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Pituicytoma

MedGen UID:
458776
Concept ID:
C2986550
Neoplastic Process
Synonyms: pituicytoma; Pituicytoma (WHO Grade 1); Pituicytoma (WHO Grade I); pituicytoma (WHO grade I); Posterior Pituitary Astrocytoma; posterior pituitary astrocytoma; PTCY
SNOMED CT: Pituicytoma (450901008); Pituicytoma (608817003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
HPO: HP:0011754
Monarch Initiative: MONDO:0006372
Orphanet: ORPHA251623

Definition

A solid, low grade, spindle cell, glial neoplasm of adults that originates in the neurohypophysis or infundibulum. Clinical signs and symptoms include visual disturbance, headache and features of hypopituitarism. Pituicytomas are well-circumscribed, solid masses that can measure up to several centimeters. Histologically, they show a compact architecture consisting of elongate, bipolar spindle cells arranged in interlacing fascicles or assuming a storiform pattern. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPituicytoma
Follow this link to review classifications for Pituicytoma in Orphanet.

Professional guidelines

PubMed

Trifa A, Knafo S, Maatoug A, Militaru M, Copaciu R, Aghakhani N, Parker F
Acta Neurol Belg 2023 Jun;123(3):815-822. Epub 2022 Mar 17 doi: 10.1007/s13760-022-01917-0. PMID: 35301693
Zoli M, Guaraldi F, Zoia C, La Corte E, Asioli S, Bongetta D, Rustici A, Mazzatenta D
Pituitary 2021 Apr;24(2):269-283. Epub 2020 Nov 17 doi: 10.1007/s11102-020-01107-2. PMID: 33200305Free PMC Article
Wang J, Liu Z, Du J, Cui Y, Fang J, Xu L, Li G
Neuropathology 2016 Oct;36(5):432-440. Epub 2016 Feb 26 doi: 10.1111/neup.12291. PMID: 26919073

Recent clinical studies

Etiology

Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Wei LD, Li C, Li D, Liu XJ, Li RT, Li LW, Wang JM, Zhou DB
Pituitary 2021 Oct;24(5):754-767. Epub 2021 May 12 doi: 10.1007/s11102-021-01152-5. PMID: 33982223Free PMC Article
Ellis JA, Tsankova NM, D'Amico R, Ausiello JC, Canoll P, Rosenblum MK, Bruce JN
World Neurosurg 2012 Jul;78(1-2):191.E1-7. Epub 2011 Nov 7 doi: 10.1016/j.wneu.2011.09.011. PMID: 22120271Free PMC Article
Covington MF, Chin SS, Osborn AG
AJNR Am J Neuroradiol 2011 Dec;32(11):2067-72. Epub 2011 Sep 29 doi: 10.3174/ajnr.A2717. PMID: 21960498Free PMC Article
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P
Acta Neuropathol 2007 Aug;114(2):97-109. Epub 2007 Jul 6 doi: 10.1007/s00401-007-0243-4. PMID: 17618441Free PMC Article

Diagnosis

Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Wei LD, Li C, Li D, Liu XJ, Li RT, Li LW, Wang JM, Zhou DB
Pituitary 2021 Oct;24(5):754-767. Epub 2021 May 12 doi: 10.1007/s11102-021-01152-5. PMID: 33982223Free PMC Article
Schwetye KE, Dahiya SM
Surg Pathol Clin 2020 Jun;13(2):305-329. doi: 10.1016/j.path.2020.02.006. PMID: 32389269
Salge-Arrieta FJ, Carrasco-Moro R, Rodríguez-Berrocal V, Pian H, Martínez-San Millán JS, Iglesias P, Ley-Urzáiz L
J Endocrinol Invest 2019 Apr;42(4):371-384. Epub 2018 Jul 20 doi: 10.1007/s40618-018-0923-z. PMID: 30030746
Wang J, Liu Z, Du J, Cui Y, Fang J, Xu L, Li G
Neuropathology 2016 Oct;36(5):432-440. Epub 2016 Feb 26 doi: 10.1111/neup.12291. PMID: 26919073

Therapy

Viaene AN, Lee EB, Nasrallah MP
Diagn Cytopathol 2020 Apr;48(4):342-349. Epub 2019 Dec 28 doi: 10.1002/dc.24372. PMID: 31883319
Sollfrank L, Lettmaier S, Erdmann M, Uslu U
Anticancer Res 2019 Jul;39(7):3955-3959. doi: 10.21873/anticanres.13549. PMID: 31262927
Amano K, Aihara Y, Tsuzuki S, Okada Y, Kawamata T
Acta Neurochir (Wien) 2019 Apr;161(4):695-706. Epub 2019 Feb 14 doi: 10.1007/s00701-018-03778-0. PMID: 30762125
Guerrero-Pérez F, Vidal N, Marengo AP, Pozo CD, Blanco C, Rivero-Celada D, Díez JJ, Iglesias P, Picó A, Villabona C
Endocrine 2019 Jan;63(1):36-43. Epub 2018 Oct 1 doi: 10.1007/s12020-018-1774-2. PMID: 30276594
Ida CM, Yan X, Jentoft ME, Kip NS, Scheithauer BW, Morris JM, Dogan A, Parisi JE, Kovacs K
Endocr Pathol 2013 Sep;24(3):149-55. doi: 10.1007/s12022-013-9254-y. PMID: 23817895

Prognosis

Wei LD, Li C, Li D, Liu XJ, Li RT, Li LW, Wang JM, Zhou DB
Pituitary 2021 Oct;24(5):754-767. Epub 2021 May 12 doi: 10.1007/s11102-021-01152-5. PMID: 33982223Free PMC Article
Asa SL, Mete O, Ezzat S
Endocr Pathol 2021 Mar;32(1):3-16. Epub 2021 Jan 12 doi: 10.1007/s12022-021-09663-4. PMID: 33433883
Guo X, Fu H, Kong X, Gao L, Wang W, Ma W, Yao Y, Wang R, Xing B
Medicine (Baltimore) 2016 Mar;95(10):e3062. doi: 10.1097/MD.0000000000003062. PMID: 26962837Free PMC Article
Ellis JA, Tsankova NM, D'Amico R, Ausiello JC, Canoll P, Rosenblum MK, Bruce JN
World Neurosurg 2012 Jul;78(1-2):191.E1-7. Epub 2011 Nov 7 doi: 10.1016/j.wneu.2011.09.011. PMID: 22120271Free PMC Article
Pirayesh Islamian A, Buslei R, Saeger W, Fahlbusch R
Pituitary 2012 Jun;15(2):227-36. doi: 10.1007/s11102-011-0317-0. PMID: 21597973

Clinical prediction guides

Trifa A, Knafo S, Maatoug A, Militaru M, Copaciu R, Aghakhani N, Parker F
Acta Neurol Belg 2023 Jun;123(3):815-822. Epub 2022 Mar 17 doi: 10.1007/s13760-022-01917-0. PMID: 35301693
Schmid S, Solomon DA, Perez E, Thieme A, Kleinschmidt-DeMasters BK, Giannini C, Reinhardt A, Asa SL, Mete O, Stichel D, Siewert C, Dittmayer C, Hasselblatt M, Paulus W, Nagel C, Harter PN, Schittenhelm J, Honegger J, Rushing E, Coras R, Pfister SM, Buslei R, Koch A, Perry A, Jones DTW, von Deimling A, Capper D, Lopes MB
Acta Neuropathol 2021 Dec;142(6):1025-1043. Epub 2021 Oct 18 doi: 10.1007/s00401-021-02377-1. PMID: 34661724Free PMC Article
Saeger W, von Schöning J, Flitsch J, Jautzke G, Bergmann M, Hagel C, Knappe UJ
Endocr Pathol 2021 Dec;32(4):473-479. Epub 2021 Jun 15 doi: 10.1007/s12022-021-09677-y. PMID: 34129177
Teti C, Castelletti L, Allegretti L, Talco M, Zona G, Minuto F, Boschetti M, Ferone D
Pituitary 2015 Oct;18(5):592-7. doi: 10.1007/s11102-014-0612-7. PMID: 25311104
Kowalski RJ, Prayson RA, Mayberg MR
Ann Diagn Pathol 2004 Oct;8(5):290-4. doi: 10.1016/j.anndiagpath.2004.07.006. PMID: 15494936

Recent systematic reviews

Zoli M, Guaraldi F, Zoia C, La Corte E, Asioli S, Bongetta D, Rustici A, Mazzatenta D
Pituitary 2021 Apr;24(2):269-283. Epub 2020 Nov 17 doi: 10.1007/s11102-020-01107-2. PMID: 33200305Free PMC Article
Whipple SG, Savardekar AR, Rao S, Mahadevan A, Guthikonda B, Kosty JA
World Neurosurg 2021 Jan;145:148-158. Epub 2020 Sep 8 doi: 10.1016/j.wneu.2020.09.023. PMID: 32916355
Guerrero-Pérez F, Marengo AP, Vidal N, Iglesias P, Villabona C
Rev Endocr Metab Disord 2019 Jun;20(2):219-238. doi: 10.1007/s11154-019-09484-1. PMID: 30864049

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