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Pancreatic Intraepithelial Neoplasia-1A

MedGen UID:
459368
•Concept ID:
C2987142
•
Neoplastic Process

Definition

A pancreatic intraepithelial neoplasia characterized by the presence of tall columnar cells that form flat architectural patterns. Mild cytological atypia is present. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPancreatic Intraepithelial Neoplasia-1A

Recent clinical studies

Prognosis

Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition.
Mizuuchi Y, Aishima S, Ohuchida K, Shindo K, Fujino M, Hattori M, Miyazaki T, Mizumoto K, Tanaka M, Oda Y
Lab Invest 2015 Feb;95(2):193-206. Epub 2014 Nov 24 doi: 10.1038/labinvest.2014.138. PMID: 25418581
Significance of DNA methyltransferase-1 and histone deacetylase-1 in pancreatic cancer.
Wang W, Gao J, Man XH, Li ZS, Gong YF
Oncol Rep 2009 Jun;21(6):1439-47. doi: 10.3892/or_00000372. PMID: 19424621

Clinical prediction guides

Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition.
Mizuuchi Y, Aishima S, Ohuchida K, Shindo K, Fujino M, Hattori M, Miyazaki T, Mizumoto K, Tanaka M, Oda Y
Lab Invest 2015 Feb;95(2):193-206. Epub 2014 Nov 24 doi: 10.1038/labinvest.2014.138. PMID: 25418581

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