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Pancreatic Mucinous-Cystic Neoplasm, Low Grade

MedGen UID:
459405
Concept ID:
C2987179
Neoplastic Process
Synonyms: Pancreatic Mucinous Cystic Neoplasm with Low Grade Dysplasia; Pancreatic Mucinous Cystic Neoplasm with Low-Grade Dysplasia; Pancreatic Mucinous-Cystic Neoplasm with Low Grade Dysplasia; Pancreatic Mucinous-Cystic Neoplasm, Low-Grade

Definition

A non-invasive mucinous cystic neoplasm that arises from the pancreas and is characterized by the presence of mild dysplasia and absence of mitotic figures. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPancreatic Mucinous-Cystic Neoplasm, Low Grade

Professional guidelines

PubMed

Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article
Basturk O, Coban I, Adsay NV
Arch Pathol Lab Med 2009 Mar;133(3):423-38. doi: 10.5858/133.3.423. PMID: 19260748
Brugge WR
World J Gastroenterol 2008 Feb 21;14(7):1038-43. doi: 10.3748/wjg.14.1038. PMID: 18286685Free PMC Article

Recent clinical studies

Etiology

Chhoda A, Schmidt J, Farrell JJ
Gastrointest Endosc Clin N Am 2023 Jul;33(3):613-640. Epub 2023 Apr 24 doi: 10.1016/j.giec.2023.03.010. PMID: 37245939
Sigel C, Wei XJ, Agaram N, Sigel K, Raza R, Andrade R, Rao R, Shah P, Soares K, Goyal A
Cancer Cytopathol 2023 May;131(5):325-336. Epub 2023 Jan 17 doi: 10.1002/cncy.22681. PMID: 36650420Free PMC Article
Nasca V, Chiaravalli M, Piro G, Esposito A, Salvatore L, Tortora G, Corbo V, Carbone C
Int J Mol Sci 2020 Sep 2;21(17) doi: 10.3390/ijms21176386. PMID: 32887490Free PMC Article
Al Efishat M, Allen PJ
Surg Oncol Clin N Am 2016 Apr;25(2):351-61. doi: 10.1016/j.soc.2015.11.006. PMID: 27013369Free PMC Article
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article

Diagnosis

Chhoda A, Schmidt J, Farrell JJ
Gastrointest Endosc Clin N Am 2023 Jul;33(3):613-640. Epub 2023 Apr 24 doi: 10.1016/j.giec.2023.03.010. PMID: 37245939
Sigel C, Wei XJ, Agaram N, Sigel K, Raza R, Andrade R, Rao R, Shah P, Soares K, Goyal A
Cancer Cytopathol 2023 May;131(5):325-336. Epub 2023 Jan 17 doi: 10.1002/cncy.22681. PMID: 36650420Free PMC Article
Köker IH, Elagöz Ş, Gücin Z, Malya FÜ, Şenturk H
Turk J Gastroenterol 2021 Sep;32(9):735-741. doi: 10.5152/tjg.2021.21318. PMID: 34609302Free PMC Article
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article
Brugge WR
World J Gastroenterol 2008 Feb 21;14(7):1038-43. doi: 10.3748/wjg.14.1038. PMID: 18286685Free PMC Article

Therapy

Chen X, Chen W, Zhang Y, An Y, Zhang X
Med Sci Monit 2020 Sep 16;26:e927248. doi: 10.12659/MSM.927248. PMID: 32935663Free PMC Article
Gurzu S, Bara T, Sincu M, Gabos S, Vlad DM, Bara T Jr, Beres H, Jung I
Medicine (Baltimore) 2019 Jul;98(29):e16455. doi: 10.1097/MD.0000000000016455. PMID: 31335701Free PMC Article
Al-Qaoud TM, Martinez EJ, Sollinger HW, Kaufman DB, Redfield RR 3rd, Welch B, Leverson G, Odorico JS
Am J Transplant 2018 Feb;18(2):467-477. Epub 2017 Nov 15 doi: 10.1111/ajt.14540. PMID: 29024476
Blackham AU, Doepker MP, Centeno BA, Springett G, Pimiento JM, Malafa M, Hodul PJ
HPB (Oxford) 2017 Jul;19(7):603-610. Epub 2017 May 9 doi: 10.1016/j.hpb.2017.03.007. PMID: 28495434
Yip-Schneider MT, Wu H, Dumas RP, Hancock BA, Agaram N, Radovich M, Schmidt CM
J Am Coll Surg 2014 Apr;218(4):608-17. Epub 2013 Dec 24 doi: 10.1016/j.jamcollsurg.2013.12.019. PMID: 24491241

Prognosis

Köker IH, Elagöz Ş, Gücin Z, Malya FÜ, Şenturk H
Turk J Gastroenterol 2021 Sep;32(9):735-741. doi: 10.5152/tjg.2021.21318. PMID: 34609302Free PMC Article
Nasca V, Chiaravalli M, Piro G, Esposito A, Salvatore L, Tortora G, Corbo V, Carbone C
Int J Mol Sci 2020 Sep 2;21(17) doi: 10.3390/ijms21176386. PMID: 32887490Free PMC Article
Kim JY, Hong SM
Oncol Res Treat 2018;41(10):603-610. Epub 2018 Sep 28 doi: 10.1159/000493554. PMID: 30269131
Al Efishat M, Allen PJ
Surg Oncol Clin N Am 2016 Apr;25(2):351-61. doi: 10.1016/j.soc.2015.11.006. PMID: 27013369Free PMC Article
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article

Clinical prediction guides

Zu G, Chen W, Wu D, Zhang Y, Chen X
BMC Surg 2023 Sep 21;23(1):288. doi: 10.1186/s12893-023-02170-9. PMID: 37735367Free PMC Article
Köker IH, Elagöz Ş, Gücin Z, Malya FÜ, Şenturk H
Turk J Gastroenterol 2021 Sep;32(9):735-741. doi: 10.5152/tjg.2021.21318. PMID: 34609302Free PMC Article
Nasca V, Chiaravalli M, Piro G, Esposito A, Salvatore L, Tortora G, Corbo V, Carbone C
Int J Mol Sci 2020 Sep 2;21(17) doi: 10.3390/ijms21176386. PMID: 32887490Free PMC Article
Al Efishat M, Allen PJ
Surg Oncol Clin N Am 2016 Apr;25(2):351-61. doi: 10.1016/j.soc.2015.11.006. PMID: 27013369Free PMC Article
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article

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