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Esophageal Diffuse Large B-Cell Lymphoma

MedGen UID:
459494
•Concept ID:
C2987268
•
Neoplastic Process
Synonym: Esophageal DLBCL

Definition

An extranodal diffuse large B-cell lymphoma that arises from the esophagus with the bulk of the mass located in the esophagus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEsophageal Diffuse Large B-Cell Lymphoma

Professional guidelines

PubMed

APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.
Zhao S, Li Y, Xu J, Shen L
Neurol Res 2024 Mar;46(3):227-242. Epub 2024 Jan 22 doi: 10.1080/01616412.2023.2287340. PMID: 38007705
TREATMENT OF MALIGNANT TUMOURS WITH 5-FLUOROURACIL IN 80 PATIENTS.
MYHRE K, FJAERLI J
Acta Radiol Ther Phys Biol 1964 Apr;2:129-38. doi: 10.3109/02841866409134138. PMID: 14162829

Recent clinical studies

Etiology

Primary Esophageal Diffuse Large B-Cell Lymphoma: A Comparative Review of 15 Cases.
Inayat F, Munir A, Wahab A, Younus F, Zafar F, Ullah W
J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618820887. doi: 10.1177/2324709618820887. PMID: 30764662Free PMC Article
Early surgical intervention for spinal infection in patients with malignancy requiring chemotherapy: report of two cases and review of the literature.
Nagashima H, Nanjo Y, Tanida A, Dokai T, Yamane K, Teshima R
Eur J Orthop Surg Traumatol 2013 Nov;23 Suppl 2:S155-8. Epub 2012 Sep 23 doi: 10.1007/s00590-012-1081-1. PMID: 23412213
Retracted: Increased risk of stomach and esophageal malignancies in people with AIDS.
Persson EC, Shiels MS, Dawsey SM, Bhatia K, Anderson LA, Engels EA
Gastroenterology 2012 Oct;143(4):943-950.e2. Epub 2012 Jul 14 doi: 10.1053/j.gastro.2012.07.013. PMID: 22796240Free PMC Article
Extended mantle radiotherapy in Hodgkin's disease and malignant lymphoma.
Marks JE, Moran EM, Griem ML, Ultmann JE
Am J Roentgenol Radium Ther Nucl Med 1974 Aug;121(4):772-88. doi: 10.2214/ajr.121.4.772. PMID: 4611242
Malignancy in adult coeliac disease and idiopathic steatorrhoea.
Harris OD, Cooke WT, Thompson H, Waterhouse JA
Am J Med 1967 Jun;42(6):899-912. doi: 10.1016/0002-9343(67)90071-x. PMID: 5338480

Diagnosis

AIDS-associated Esophageal Plasmablastic Lymphoma.
Abdulla HM, Cohn S
Clin Gastroenterol Hepatol 2021 Jan;19(1):A18. Epub 2019 Dec 27 doi: 10.1016/j.cgh.2019.12.027. PMID: 31887446
Primary cardiac lymphoma.
Chia AXF, Zhao Z, Lim SL
BMJ Case Rep 2019 Dec 2;12(12) doi: 10.1136/bcr-2019-230468. PMID: 31796452Free PMC Article
Portal hypertension due to intrahepatic obstruction in non-Hodgkin's lymphoma.
Bachmeyer C, Harry G, Cazier A, Bonnard P, Cadranel JF
Eur J Gastroenterol Hepatol 2001 Dec;13(12):1491-3. doi: 10.1097/00042737-200112000-00014. PMID: 11742199
Chronic lymphocytic leukemia: an unusual cause of upper gastrointestinal hemorrhage.
Faigel DO, Vaughn DJ, Furth EE, Metz DC
Am J Gastroenterol 1995 Apr;90(4):635-7. PMID: 7717324
Hepatocellular carcinoma associated with second primary malignancy.
Lin DY, Liaw YF, Wu CS, Chang-Chien CS, Chen PC, Chen TJ
Liver 1987 Apr;7(2):106-9. doi: 10.1111/j.1600-0676.1987.tb00325.x. PMID: 3039283

Therapy

Precision medicine for human cancers with Notch signaling dysregulation (Review).
Katoh M, Katoh M
Int J Mol Med 2020 Feb;45(2):279-297. Epub 2019 Dec 4 doi: 10.3892/ijmm.2019.4418. PMID: 31894255Free PMC Article
Primary cardiac lymphoma.
Chia AXF, Zhao Z, Lim SL
BMJ Case Rep 2019 Dec 2;12(12) doi: 10.1136/bcr-2019-230468. PMID: 31796452Free PMC Article
Atypical cutaneous targetoid lesions after bone marrow transplant.
Zhong CS, Richardson ET, Laga Canales AC, Nambudiri VE
BMJ Case Rep 2019 Aug 12;12(8) doi: 10.1136/bcr-2019-230142. PMID: 31409617Free PMC Article
The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
Chang S, Yim S, Park H
Exp Mol Med 2019 Jun 20;51(6):1-17. doi: 10.1038/s12276-019-0230-6. PMID: 31221981Free PMC Article
The Elusive Diagnosis of Primary Esophageal Lymphoma.
Mrad RA, El-Majzoub N, Shamseddine A, Soweid A
Turk J Haematol 2018 Aug 3;35(3):199. Epub 2017 Mar 8 doi: 10.4274/tjh.2016.0482. PMID: 28270375Free PMC Article

Prognosis

The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
Chang S, Yim S, Park H
Exp Mol Med 2019 Jun 20;51(6):1-17. doi: 10.1038/s12276-019-0230-6. PMID: 31221981Free PMC Article
Retracted: Increased risk of stomach and esophageal malignancies in people with AIDS.
Persson EC, Shiels MS, Dawsey SM, Bhatia K, Anderson LA, Engels EA
Gastroenterology 2012 Oct;143(4):943-950.e2. Epub 2012 Jul 14 doi: 10.1053/j.gastro.2012.07.013. PMID: 22796240Free PMC Article
Chronic lymphocytic leukemia: an unusual cause of upper gastrointestinal hemorrhage.
Faigel DO, Vaughn DJ, Furth EE, Metz DC
Am J Gastroenterol 1995 Apr;90(4):635-7. PMID: 7717324
The course and prognosis in some types of carcinomatous neuromyopathy.
Croft PB, Wilkinson M
Brain 1969 Mar;92(1):1-8. doi: 10.1093/brain/92.1.1. PMID: 4304423
Malignancy in adult coeliac disease and idiopathic steatorrhoea.
Harris OD, Cooke WT, Thompson H, Waterhouse JA
Am J Med 1967 Jun;42(6):899-912. doi: 10.1016/0002-9343(67)90071-x. PMID: 5338480

Clinical prediction guides

Comprehensive Bioinformatic Investigation of TP53 Dysregulation in Diverse Cancer Landscapes.
Khan R, Pari B, Puszynski K
Genes (Basel) 2024 Apr 30;15(5) doi: 10.3390/genes15050577. PMID: 38790205Free PMC Article
Allogeneic CAR-T cells with of HLA-A/B and TRAC disruption exhibit promising antitumor capacity against B cell malignancies.
Chen X, Tan B, Xing H, Zhao X, Ping Y, Zhang Z, Huang J, Shi X, Zhang N, Lin B, Cao W, Li X, Zhang X, Li L, Jiang Z, Zhang M, Li W, Liu M, Du B, Zhang Y
Cancer Immunol Immunother 2024 Jan 17;73(1):13. doi: 10.1007/s00262-023-03586-1. PMID: 38231412Free PMC Article
APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.
Zhao S, Li Y, Xu J, Shen L
Neurol Res 2024 Mar;46(3):227-242. Epub 2024 Jan 22 doi: 10.1080/01616412.2023.2287340. PMID: 38007705
Identification and Validation of a Prognostic Prediction Model in Diffuse Large B-Cell Lymphoma.
Yan J, Yuan W, Zhang J, Li L, Zhang L, Zhang X, Zhang M
Front Endocrinol (Lausanne) 2022;13:846357. Epub 2022 Apr 14 doi: 10.3389/fendo.2022.846357. PMID: 35498426Free PMC Article
The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
Chang S, Yim S, Park H
Exp Mol Med 2019 Jun 20;51(6):1-17. doi: 10.1038/s12276-019-0230-6. PMID: 31221981Free PMC Article

Recent systematic reviews

Primary esophageal non-Hodgkin's lymphoma: demographics, clinical characteristics, histopathologic types, and survival in 179 patients from the SEER program and systematic review of the literature.
Quiroga-Centeno AC, Bautista-Parada IR, Tapias LF, Gómez-Ochoa SA
Esophagus 2021 Oct;18(4):734-742. Epub 2021 Apr 20 doi: 10.1007/s10388-021-00842-0. PMID: 33880688
Prognostic role of secreted protein acidic and rich in cysteine in patients with solid tumors.
Ma Y, Chen H, Ma H, Yao Z, Hu J, Ma J, Zhang X, Chen G, Liu Y
Saudi Med J 2019 Aug;40(8):755-765. doi: 10.15537/smj.2019.8.24379. PMID: 31423511Free PMC Article
Body fatness at a young age and risks of eight types of cancer: systematic review and meta-analysis of observational studies.
Hidayat K, Du X, Shi BM
Obes Rev 2018 Oct;19(10):1385-1394. Epub 2018 Jul 25 doi: 10.1111/obr.12705. PMID: 30047231
Esophagogastric cancer after bariatric surgery: systematic review of the literature.
Scozzari G, Trapani R, Toppino M, Morino M
Surg Obes Relat Dis 2013 Jan-Feb;9(1):133-42. Epub 2012 Oct 12 doi: 10.1016/j.soard.2012.10.002. PMID: 23265766

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