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Negative for Gastric Dysplasia

MedGen UID:
459627
Concept ID:
C2987401
Finding
Synonym: Negative for Gastric Intraepithelial Neoplasia

Definition

A morphologic finding indicating the absence of dysplastic changes in the gastric mucosal epithelium. It includes non-neoplastic inflammatory, reactive, or metaplastic pathologic processes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNegative for Gastric Dysplasia

Professional guidelines

PubMed

Waters KM, Salimian KJ, Voltaggio L, Montgomery EA
Am J Surg Pathol 2018 Dec;42(12):1723-1729. doi: 10.1097/PAS.0000000000001162. PMID: 30234520
Naini BV, Chak A, Ali MA, Odze RD
Best Pract Res Clin Gastroenterol 2015 Feb;29(1):77-96. Epub 2014 Nov 13 doi: 10.1016/j.bpg.2014.11.004. PMID: 25743458
Armstrong D, Marshall JK, Chiba N, Enns R, Fallone CA, Fass R, Hollingworth R, Hunt RH, Kahrilas PJ, Mayrand S, Moayyedi P, Paterson WG, Sadowski D, van Zanten SJ; Canadian Association of Gastroenterology GERD Consensus Group
Can J Gastroenterol 2005 Jan;19(1):15-35. doi: 10.1155/2005/836030. PMID: 15685294

Recent clinical studies

Etiology

Rugge M, Bricca L, Guzzinati S, Sacchi D, Pizzi M, Savarino E, Farinati F, Zorzi M, Fassan M, Dei Tos AP, Malfertheiner P, Genta RM, Graham DY
Gut 2023 Jan;72(1):30-38. Epub 2022 Jun 30 doi: 10.1136/gutjnl-2022-327827. PMID: 35772926
Piazuelo MB, Bravo LE, Mera RM, Camargo MC, Bravo JC, Delgado AG, Washington MK, Rosero A, Garcia LS, Realpe JL, Cifuentes SP, Morgan DR, Peek RM Jr, Correa P, Wilson KT
Gastroenterology 2021 Mar;160(4):1106-1117.e3. Epub 2020 Nov 18 doi: 10.1053/j.gastro.2020.11.017. PMID: 33220252Free PMC Article
Guo Y, Zhang Y, Gerhard M, Gao JJ, Mejias-Luque R, Zhang L, Vieth M, Ma JL, Bajbouj M, Suchanek S, Liu WD, Ulm K, Quante M, Li ZX, Zhou T, Schmid R, Classen M, Li WQ, You WC, Pan KF
Gut 2020 Sep;69(9):1598-1607. Epub 2019 Dec 19 doi: 10.1136/gutjnl-2019-319696. PMID: 31857433Free PMC Article
Venerito M, Vasapolli R, Malfertheiner P
Adv Exp Med Biol 2016;908:409-18. doi: 10.1007/978-3-319-41388-4_20. PMID: 27573783
Misdraji J, Lauwers GY
Semin Diagn Pathol 2002 Feb;19(1):20-30. PMID: 11936263

Diagnosis

Wong MT, Singhi AD, Larson BK, Huynh CAT, Balzer BL, Burch M, Dhall D, Gangi A, Gong J, Guindi M, Hendifar AE, Kim SA, de Peralta-Venturina M, Waters KM
Arch Pathol Lab Med 2022 May 1;147(5):559-567. doi: 10.5858/arpa.2021-0428-OA. PMID: 35976638
Piazuelo MB, Bravo LE, Mera RM, Camargo MC, Bravo JC, Delgado AG, Washington MK, Rosero A, Garcia LS, Realpe JL, Cifuentes SP, Morgan DR, Peek RM Jr, Correa P, Wilson KT
Gastroenterology 2021 Mar;160(4):1106-1117.e3. Epub 2020 Nov 18 doi: 10.1053/j.gastro.2020.11.017. PMID: 33220252Free PMC Article
Guo Y, Zhang Y, Gerhard M, Gao JJ, Mejias-Luque R, Zhang L, Vieth M, Ma JL, Bajbouj M, Suchanek S, Liu WD, Ulm K, Quante M, Li ZX, Zhou T, Schmid R, Classen M, Li WQ, You WC, Pan KF
Gut 2020 Sep;69(9):1598-1607. Epub 2019 Dec 19 doi: 10.1136/gutjnl-2019-319696. PMID: 31857433Free PMC Article
Mori Y, Kudo SE, Mohmed HEN, Misawa M, Ogata N, Itoh H, Oda M, Mori K
Dig Endosc 2019 Jul;31(4):378-388. Epub 2019 Feb 14 doi: 10.1111/den.13317. PMID: 30549317
Misdraji J, Lauwers GY
Semin Diagn Pathol 2002 Feb;19(1):20-30. PMID: 11936263

Therapy

Wong MT, Singhi AD, Larson BK, Huynh CAT, Balzer BL, Burch M, Dhall D, Gangi A, Gong J, Guindi M, Hendifar AE, Kim SA, de Peralta-Venturina M, Waters KM
Arch Pathol Lab Med 2022 May 1;147(5):559-567. doi: 10.5858/arpa.2021-0428-OA. PMID: 35976638
Piazuelo MB, Bravo LE, Mera RM, Camargo MC, Bravo JC, Delgado AG, Washington MK, Rosero A, Garcia LS, Realpe JL, Cifuentes SP, Morgan DR, Peek RM Jr, Correa P, Wilson KT
Gastroenterology 2021 Mar;160(4):1106-1117.e3. Epub 2020 Nov 18 doi: 10.1053/j.gastro.2020.11.017. PMID: 33220252Free PMC Article
Guo Y, Zhang Y, Gerhard M, Gao JJ, Mejias-Luque R, Zhang L, Vieth M, Ma JL, Bajbouj M, Suchanek S, Liu WD, Ulm K, Quante M, Li ZX, Zhou T, Schmid R, Classen M, Li WQ, You WC, Pan KF
Gut 2020 Sep;69(9):1598-1607. Epub 2019 Dec 19 doi: 10.1136/gutjnl-2019-319696. PMID: 31857433Free PMC Article
Venerito M, Vasapolli R, Malfertheiner P
Adv Exp Med Biol 2016;908:409-18. doi: 10.1007/978-3-319-41388-4_20. PMID: 27573783
Venerito M, Vasapolli R, Rokkas T, Malfertheiner P
Helicobacter 2015 Sep;20 Suppl 1:36-9. doi: 10.1111/hel.12255. PMID: 26372823

Prognosis

Rugge M, Bricca L, Guzzinati S, Sacchi D, Pizzi M, Savarino E, Farinati F, Zorzi M, Fassan M, Dei Tos AP, Malfertheiner P, Genta RM, Graham DY
Gut 2023 Jan;72(1):30-38. Epub 2022 Jun 30 doi: 10.1136/gutjnl-2022-327827. PMID: 35772926
Piazuelo MB, Bravo LE, Mera RM, Camargo MC, Bravo JC, Delgado AG, Washington MK, Rosero A, Garcia LS, Realpe JL, Cifuentes SP, Morgan DR, Peek RM Jr, Correa P, Wilson KT
Gastroenterology 2021 Mar;160(4):1106-1117.e3. Epub 2020 Nov 18 doi: 10.1053/j.gastro.2020.11.017. PMID: 33220252Free PMC Article
Kim JL, Kim SG, Lee A, Choi J, Chung H, Cho SJ
Surg Endosc 2021 Sep;35(9):5247-5255. Epub 2020 Sep 28 doi: 10.1007/s00464-020-08023-3. PMID: 32989550
Cho YS, Chung IK, Jung Y, Han SJ, Yang JK, Lee TH, Park SH, Kim SJ
Korean J Intern Med 2021 Sep;36(5):1074-1082. Epub 2020 Sep 9 doi: 10.3904/kjim.2018.285. PMID: 32898394Free PMC Article
Kumarasinghe MP, Bourke MJ, Brown I, Draganov PV, McLeod D, Streutker C, Raftopoulos S, Ushiku T, Lauwers GY
Mod Pathol 2020 Jun;33(6):986-1006. Epub 2020 Jan 6 doi: 10.1038/s41379-019-0443-1. PMID: 31907377

Clinical prediction guides

Rugge M, Bricca L, Guzzinati S, Sacchi D, Pizzi M, Savarino E, Farinati F, Zorzi M, Fassan M, Dei Tos AP, Malfertheiner P, Genta RM, Graham DY
Gut 2023 Jan;72(1):30-38. Epub 2022 Jun 30 doi: 10.1136/gutjnl-2022-327827. PMID: 35772926
Shi Z, Zhu C, Zhang Y, Wang Y, Hou W, Li X, Lu J, Guo X, Xu F, Jiang X, Wang Y, Liu J, Jin M
Gastric Cancer 2022 Jul;25(4):751-760. Epub 2022 Apr 8 doi: 10.1007/s10120-022-01294-w. PMID: 35394573
Piazuelo MB, Bravo LE, Mera RM, Camargo MC, Bravo JC, Delgado AG, Washington MK, Rosero A, Garcia LS, Realpe JL, Cifuentes SP, Morgan DR, Peek RM Jr, Correa P, Wilson KT
Gastroenterology 2021 Mar;160(4):1106-1117.e3. Epub 2020 Nov 18 doi: 10.1053/j.gastro.2020.11.017. PMID: 33220252Free PMC Article
Cho YS, Chung IK, Jung Y, Han SJ, Yang JK, Lee TH, Park SH, Kim SJ
Korean J Intern Med 2021 Sep;36(5):1074-1082. Epub 2020 Sep 9 doi: 10.3904/kjim.2018.285. PMID: 32898394Free PMC Article
Kumarasinghe MP, Bourke MJ, Brown I, Draganov PV, McLeod D, Streutker C, Raftopoulos S, Ushiku T, Lauwers GY
Mod Pathol 2020 Jun;33(6):986-1006. Epub 2020 Jan 6 doi: 10.1038/s41379-019-0443-1. PMID: 31907377

Recent systematic reviews

Huang Y, Yang Z, Yao Y, Liu G, Chen R
Tech Coloproctol 2023 Dec;27(12):1155-1167. Epub 2023 Jul 20 doi: 10.1007/s10151-023-02833-y. PMID: 37474693
Du YL, Duan RQ, Duan LP
BMC Gastroenterol 2021 Dec 7;21(1):459. doi: 10.1186/s12876-021-02036-5. PMID: 34876031Free PMC Article

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