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Cardiac Arrest/Arrhythmia Etiology Unknown

MedGen UID:
473910
Concept ID:
C3272277
Finding

Definition

An episode of cardiac arrest or arrhythmia where the etiology was unknown. (ACC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCardiac Arrest/Arrhythmia Etiology Unknown

Professional guidelines

PubMed

Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Wijeyeratne YD, Behr ER
Trends Cardiovasc Med 2017 Apr;27(3):207-213. Epub 2016 Aug 31 doi: 10.1016/j.tcm.2016.08.010. PMID: 27692676
Lampert R
Prog Cardiovasc Dis 2012 Mar-Apr;54(5):423-31. doi: 10.1016/j.pcad.2012.01.002. PMID: 22386293

Recent clinical studies

Etiology

Bai AD, Wilkinson A, Almufleh A, Rai M, Razak F, Verma AA, Srivastava S
JAMA Netw Open 2023 Oct 2;6(10):e2339893. doi: 10.1001/jamanetworkopen.2023.39893. PMID: 37883084Free PMC Article
Lampert R, Ackerman MJ, Marino BS, Burg M, Ainsworth B, Salberg L, Tome Esteban MT, Ho CY, Abraham R, Balaji S, Barth C, Berul CI, Bos M, Cannom D, Choudhury L, Concannon M, Cooper R, Czosek RJ, Dubin AM, Dziura J, Eidem B, Emery MS, Estes NAM, Etheridge SP, Geske JB, Gray B, Hall K, Harmon KG, James CA, Lal AK, Law IH, Li F, Link MS, McKenna WJ, Molossi S, Olshansky B, Ommen SR, Saarel EV, Saberi S, Simone L, Tomaselli G, Ware JS, Zipes DP, Day SM; LIVE Consortium
JAMA Cardiol 2023 Jun 1;8(6):595-605. doi: 10.1001/jamacardio.2023.1042. PMID: 37195701Free PMC Article
Dankiewicz J, Cronberg T, Lilja G, Jakobsen JC, Levin H, Ullén S, Rylander C, Wise MP, Oddo M, Cariou A, Bělohlávek J, Hovdenes J, Saxena M, Kirkegaard H, Young PJ, Pelosi P, Storm C, Taccone FS, Joannidis M, Callaway C, Eastwood GM, Morgan MPG, Nordberg P, Erlinge D, Nichol AD, Chew MS, Hollenberg J, Thomas M, Bewley J, Sweet K, Grejs AM, Christensen S, Haenggi M, Levis A, Lundin A, Düring J, Schmidbauer S, Keeble TR, Karamasis GV, Schrag C, Faessler E, Smid O, Otáhal M, Maggiorini M, Wendel Garcia PD, Jaubert P, Cole JM, Solar M, Borgquist O, Leithner C, Abed-Maillard S, Navarra L, Annborn M, Undén J, Brunetti I, Awad A, McGuigan P, Bjørkholt Olsen R, Cassina T, Vignon P, Langeland H, Lange T, Friberg H, Nielsen N; TTM2 Trial Investigators
N Engl J Med 2021 Jun 17;384(24):2283-2294. doi: 10.1056/NEJMoa2100591. PMID: 34133859
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Bhatia A, Sra J, Akhtar M
Curr Probl Cardiol 2012 Aug;37(8):317-62. doi: 10.1016/j.cpcardiol.2012.03.004. PMID: 22749026

Diagnosis

Bai AD, Wilkinson A, Almufleh A, Rai M, Razak F, Verma AA, Srivastava S
JAMA Netw Open 2023 Oct 2;6(10):e2339893. doi: 10.1001/jamanetworkopen.2023.39893. PMID: 37883084Free PMC Article
Bueno-Beti C, Lim CX, Protonotarios A, Szabo PL, Westaby J, Mazic M, Sheppard MN, Behr E, Hamza O, Kiss A, Podesser BK, Hengstschläger M, Weichhart T, Asimaki A
J Am Heart Assoc 2023 Oct 3;12(19):e030478. Epub 2023 Sep 26 doi: 10.1161/JAHA.123.030478. PMID: 37750561Free PMC Article
Lampert R, Ackerman MJ, Marino BS, Burg M, Ainsworth B, Salberg L, Tome Esteban MT, Ho CY, Abraham R, Balaji S, Barth C, Berul CI, Bos M, Cannom D, Choudhury L, Concannon M, Cooper R, Czosek RJ, Dubin AM, Dziura J, Eidem B, Emery MS, Estes NAM, Etheridge SP, Geske JB, Gray B, Hall K, Harmon KG, James CA, Lal AK, Law IH, Li F, Link MS, McKenna WJ, Molossi S, Olshansky B, Ommen SR, Saarel EV, Saberi S, Simone L, Tomaselli G, Ware JS, Zipes DP, Day SM; LIVE Consortium
JAMA Cardiol 2023 Jun 1;8(6):595-605. doi: 10.1001/jamacardio.2023.1042. PMID: 37195701Free PMC Article
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Bhatia A, Sra J, Akhtar M
Curr Probl Cardiol 2012 Aug;37(8):317-62. doi: 10.1016/j.cpcardiol.2012.03.004. PMID: 22749026

Therapy

Marcus MD, Link MS
Circulation 2024 Aug 6;150(6):488-503. Epub 2024 Aug 5 doi: 10.1161/CIRCULATIONAHA.123.065769. PMID: 39102482
Bai AD, Wilkinson A, Almufleh A, Rai M, Razak F, Verma AA, Srivastava S
JAMA Netw Open 2023 Oct 2;6(10):e2339893. doi: 10.1001/jamanetworkopen.2023.39893. PMID: 37883084Free PMC Article
Dankiewicz J, Cronberg T, Lilja G, Jakobsen JC, Levin H, Ullén S, Rylander C, Wise MP, Oddo M, Cariou A, Bělohlávek J, Hovdenes J, Saxena M, Kirkegaard H, Young PJ, Pelosi P, Storm C, Taccone FS, Joannidis M, Callaway C, Eastwood GM, Morgan MPG, Nordberg P, Erlinge D, Nichol AD, Chew MS, Hollenberg J, Thomas M, Bewley J, Sweet K, Grejs AM, Christensen S, Haenggi M, Levis A, Lundin A, Düring J, Schmidbauer S, Keeble TR, Karamasis GV, Schrag C, Faessler E, Smid O, Otáhal M, Maggiorini M, Wendel Garcia PD, Jaubert P, Cole JM, Solar M, Borgquist O, Leithner C, Abed-Maillard S, Navarra L, Annborn M, Undén J, Brunetti I, Awad A, McGuigan P, Bjørkholt Olsen R, Cassina T, Vignon P, Langeland H, Lange T, Friberg H, Nielsen N; TTM2 Trial Investigators
N Engl J Med 2021 Jun 17;384(24):2283-2294. doi: 10.1056/NEJMoa2100591. PMID: 34133859
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Napolitano C, Priori SG
Orphanet J Rare Dis 2006 Sep 14;1:35. doi: 10.1186/1750-1172-1-35. PMID: 16972995Free PMC Article

Prognosis

Mesnier J, Ternacle J, Cheema AN, Campelo-Parada F, Urena M, Veiga-Fernandez G, Nombela-Franco L, Munoz-Garcia AJ, Vilalta V, Regueiro A, Del Val D, Asmarats L, Del Trigo M, Serra V, Bonnet G, Jonveaux M, Rezaei E, Matta A, Himbert D, de la Torre Hernandez JM, Tirado-Conte G, Fernandez-Nofrerias E, Vidal P, Alfonso F, Gutierrez-Alonso L, Oteo JF, Belahnech Y, Mohammadi S, Philippon F, Modine T, Rodés-Cabau J
JACC Cardiovasc Interv 2023 Sep 25;16(18):2277-2290. doi: 10.1016/j.jcin.2023.07.015. PMID: 37758382
Sherpa MD, Sonkawade SD, Jonnala V, Pokharel S, Khazaeli M, Yatsynovich Y, Kalot MA, Weil BR, Canty JM Jr, Sharma UC
Cells 2023 Apr 23;12(9) doi: 10.3390/cells12091218. PMID: 37174619Free PMC Article
Rodríguez-Reyes H, Muñoz-Gutiérrez M, Salas-Pacheco JL
Arch Cardiol Mex 2020;90(2):183-189. doi: 10.24875/ACME.M20000114. PMID: 32897250
Rodríguez-Reyes H, Muñoz-Gutiérrez M, Salas-Pacheco JL
Arch Cardiol Mex 2020;90(2):200-206. doi: 10.24875/ACM.19000157. PMID: 32459200
Ryabkova VA, Shubik YV, Erman MV, Churilov LP, Kanduc D, Shoenfeld Y
Autoimmun Rev 2019 Apr;18(4):415-425. Epub 2019 Feb 14 doi: 10.1016/j.autrev.2018.12.005. PMID: 30772491

Clinical prediction guides

Bai AD, Wilkinson A, Almufleh A, Rai M, Razak F, Verma AA, Srivastava S
JAMA Netw Open 2023 Oct 2;6(10):e2339893. doi: 10.1001/jamanetworkopen.2023.39893. PMID: 37883084Free PMC Article
Lampert R, Ackerman MJ, Marino BS, Burg M, Ainsworth B, Salberg L, Tome Esteban MT, Ho CY, Abraham R, Balaji S, Barth C, Berul CI, Bos M, Cannom D, Choudhury L, Concannon M, Cooper R, Czosek RJ, Dubin AM, Dziura J, Eidem B, Emery MS, Estes NAM, Etheridge SP, Geske JB, Gray B, Hall K, Harmon KG, James CA, Lal AK, Law IH, Li F, Link MS, McKenna WJ, Molossi S, Olshansky B, Ommen SR, Saarel EV, Saberi S, Simone L, Tomaselli G, Ware JS, Zipes DP, Day SM; LIVE Consortium
JAMA Cardiol 2023 Jun 1;8(6):595-605. doi: 10.1001/jamacardio.2023.1042. PMID: 37195701Free PMC Article
Dankiewicz J, Cronberg T, Lilja G, Jakobsen JC, Levin H, Ullén S, Rylander C, Wise MP, Oddo M, Cariou A, Bělohlávek J, Hovdenes J, Saxena M, Kirkegaard H, Young PJ, Pelosi P, Storm C, Taccone FS, Joannidis M, Callaway C, Eastwood GM, Morgan MPG, Nordberg P, Erlinge D, Nichol AD, Chew MS, Hollenberg J, Thomas M, Bewley J, Sweet K, Grejs AM, Christensen S, Haenggi M, Levis A, Lundin A, Düring J, Schmidbauer S, Keeble TR, Karamasis GV, Schrag C, Faessler E, Smid O, Otáhal M, Maggiorini M, Wendel Garcia PD, Jaubert P, Cole JM, Solar M, Borgquist O, Leithner C, Abed-Maillard S, Navarra L, Annborn M, Undén J, Brunetti I, Awad A, McGuigan P, Bjørkholt Olsen R, Cassina T, Vignon P, Langeland H, Lange T, Friberg H, Nielsen N; TTM2 Trial Investigators
N Engl J Med 2021 Jun 17;384(24):2283-2294. doi: 10.1056/NEJMoa2100591. PMID: 34133859
Ryabkova VA, Shubik YV, Erman MV, Churilov LP, Kanduc D, Shoenfeld Y
Autoimmun Rev 2019 Apr;18(4):415-425. Epub 2019 Feb 14 doi: 10.1016/j.autrev.2018.12.005. PMID: 30772491
Wijeyeratne YD, Behr ER
Trends Cardiovasc Med 2017 Apr;27(3):207-213. Epub 2016 Aug 31 doi: 10.1016/j.tcm.2016.08.010. PMID: 27692676

Recent systematic reviews

Lawley CM, Tester M, Sanatani S, Prendiville T, Beach CM, Vinocur JM, Horie M, Uhm JS, Khongphatthanayothin A, Ayers MD, Starling L, Yoshida Y, Shah MJ, Skinner JR, Turner C
Heart Rhythm 2022 Nov;19(11):1826-1833. Epub 2022 Oct 11 doi: 10.1016/j.hrthm.2022.08.003. PMID: 37850595
Fernando SM, Di Santo P, Sadeghirad B, Lascarrou JB, Rochwerg B, Mathew R, Sekhon MS, Munshi L, Fan E, Brodie D, Rowan KM, Hough CL, McLeod SL, Vaillancourt C, Cheskes S, Ferguson ND, Scales DC, Sandroni C, Nolan JP, Hibbert B
Intensive Care Med 2021 Oct;47(10):1078-1088. Epub 2021 Aug 13 doi: 10.1007/s00134-021-06505-z. PMID: 34389870
Chahal CAA, Salloum MN, Alahdab F, Gottwald JA, Tester DJ, Anwer LA, So EL, Murad MH, St Louis EK, Ackerman MJ, Somers VK
J Am Heart Assoc 2020 Jan 7;9(1):e012264. Epub 2019 Dec 21 doi: 10.1161/JAHA.119.012264. PMID: 31865891Free PMC Article
Ha AH, Ham I, Nair GM, Connolly SJ, Dorian P, Morillo CA, Healey JS
Heart Rhythm 2012 Dec;9(12):2068-74. Epub 2012 Sep 1 doi: 10.1016/j.hrthm.2012.08.032. PMID: 23108056

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