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Small intestinal diffuse large B-cell lymphoma

MedGen UID:
474155
•Concept ID:
C3272522
•
Neoplastic Process
Synonyms: diffuse large B-cell lymphoma of small intestine; Small Intestinal Diffuse Large B-Cell Lymphoma; small intestinal diffuse large B-cell lymphoma; small intestine diffuse large B-cell lymphoma
 
Monarch Initiative: MONDO:0006417

Definition

A diffuse large B-cell lymphoma that arises from the small intestine. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSmall intestinal diffuse large B-cell lymphoma

Professional guidelines

PubMed

Review of lymphoma in the duodenum: An update of diagnosis and management.
Iwamuro M, Tanaka T, Okada H
World J Gastroenterol 2023 Mar 28;29(12):1852-1862. doi: 10.3748/wjg.v29.i12.1852. PMID: 37032723Free PMC Article
Gastrointestinal lymphoma: recent advances in diagnosis and treatment.
Nakamura S, Matsumoto T
Digestion 2013;87(3):182-8. Epub 2013 Apr 27 doi: 10.1159/000350051. PMID: 23635497
Role of radiotherapy in the treatment of lymphomas of the gastrointestinal tract.
Aleman BM, Haas RL, van der Maazen RW
Best Pract Res Clin Gastroenterol 2010 Feb;24(1):27-34. doi: 10.1016/j.bpg.2009.12.002. PMID: 20206106

Recent clinical studies

Etiology

B Cell Lymphomas of the GI Tract.
Small S, Barnea Slonim L, Williams C, Karmali R
Curr Gastroenterol Rep 2021 May 8;23(7):9. doi: 10.1007/s11894-021-00811-8. PMID: 33963950
New developments in non-Hodgkin lymphoid malignancies.
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Peripheral T-cell lymphoma: spectrum of imaging findings with clinical and pathologic features.
Lee HJ, Im JG, Goo JM, Kim KW, Choi BI, Chang KH, Han JK, Han MH
Radiographics 2003 Jan-Feb;23(1):7-26; discussion 26-8. doi: 10.1148/rg.231025018. PMID: 12533636

Diagnosis

B Cell Lymphomas of the GI Tract.
Small S, Barnea Slonim L, Williams C, Karmali R
Curr Gastroenterol Rep 2021 May 8;23(7):9. doi: 10.1007/s11894-021-00811-8. PMID: 33963950
New developments in non-Hodgkin lymphoid malignancies.
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
The recognition and classification of lymphoproliferative disorders of the gut.
O'Malley DP, Goldstein NS, Banks PM
Hum Pathol 2014 May;45(5):899-916. Epub 2013 Dec 18 doi: 10.1016/j.humpath.2013.12.001. PMID: 24613566
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article

Therapy

Extensive small intestinal diffuse large B cell lymphoma.
Liu X, Lv T, Zhang X, Li J
Rev Esp Enferm Dig 2023 May;115(5):267. doi: 10.17235/reed.2022.9100/2022. PMID: 36043558
Clinicopathological characteristics of diffuse large B-cell lymphoma involving small and large intestines: an analysis of 126 patients.
Maeshima AM, Taniguchi H, Ito Y, Hatta S, Suzuki T, Yuda S, Makita S, Fukuhara S, Munakata W, Suzuki T, Maruyama D, Izutsu K
Int J Hematol 2019 Sep;110(3):340-346. Epub 2019 Jun 11 doi: 10.1007/s12185-019-02687-x. PMID: 31187439
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Role of radiotherapy in the treatment of lymphomas of the gastrointestinal tract.
Aleman BM, Haas RL, van der Maazen RW
Best Pract Res Clin Gastroenterol 2010 Feb;24(1):27-34. doi: 10.1016/j.bpg.2009.12.002. PMID: 20206106
Peripheral T-cell lymphoma: spectrum of imaging findings with clinical and pathologic features.
Lee HJ, Im JG, Goo JM, Kim KW, Choi BI, Chang KH, Han JK, Han MH
Radiographics 2003 Jan-Feb;23(1):7-26; discussion 26-8. doi: 10.1148/rg.231025018. PMID: 12533636

Prognosis

Clinicopathological characteristics of diffuse large B-cell lymphoma involving small and large intestines: an analysis of 126 patients.
Maeshima AM, Taniguchi H, Ito Y, Hatta S, Suzuki T, Yuda S, Makita S, Fukuhara S, Munakata W, Suzuki T, Maruyama D, Izutsu K
Int J Hematol 2019 Sep;110(3):340-346. Epub 2019 Jun 11 doi: 10.1007/s12185-019-02687-x. PMID: 31187439
Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Peripheral T-cell lymphoma: spectrum of imaging findings with clinical and pathologic features.
Lee HJ, Im JG, Goo JM, Kim KW, Choi BI, Chang KH, Han JK, Han MH
Radiographics 2003 Jan-Feb;23(1):7-26; discussion 26-8. doi: 10.1148/rg.231025018. PMID: 12533636
Pathology of intestinal lymphomas.
Foss HD, Stein H
Recent Results Cancer Res 2000;156:33-41. doi: 10.1007/978-3-642-57054-4_5. PMID: 10802861

Clinical prediction guides

Reappraisal of Primary Epstein-Barr Virus (EBV)-positive Diffuse Large B-Cell Lymphoma of the Gastrointestinal Tract: Comparative Analysis Among Immunosuppressed and Nonimmunosuppressed Stage I and II-IV Patients.
Miyagi S, Ishikawa E, Nakamura M, Shimada K, Yamamura T, Furukawa K, Tanaka T, Mabuchi S, Tsuyuki Y, Kohno K, Sakakibara A, Satou A, Kato S, Fujishiro M, Nakamura S
Am J Surg Pathol 2020 Sep;44(9):1173-1183. doi: 10.1097/PAS.0000000000001499. PMID: 32349049
Clinicopathological characteristics of diffuse large B-cell lymphoma involving small and large intestines: an analysis of 126 patients.
Maeshima AM, Taniguchi H, Ito Y, Hatta S, Suzuki T, Yuda S, Makita S, Fukuhara S, Munakata W, Suzuki T, Maruyama D, Izutsu K
Int J Hematol 2019 Sep;110(3):340-346. Epub 2019 Jun 11 doi: 10.1007/s12185-019-02687-x. PMID: 31187439
Composite lymphoma with diffuse large B-cell lymphoma and classical Hodgkin lymphoma components: A case report and review of the literature.
Goyal G, Nguyen AH, Kendric K, Caponetti GC
Pathol Res Pract 2016 Dec;212(12):1179-1190. Epub 2016 Nov 5 doi: 10.1016/j.prp.2016.11.002. PMID: 27887763
Prognostic value of chromosomal translocations in small-bowel diffuse large B-cell lymphoma.
Ikegami K, Nakamura S, Esaki M, Yanai S, Hirahashi M, Oda Y, Takeshita M, Matsumoto T, Kitazono T
Histopathology 2016 Jan;68(2):199-209. Epub 2015 Jun 18 doi: 10.1111/his.12731. PMID: 25953462
Pathology of intestinal lymphomas.
Foss HD, Stein H
Recent Results Cancer Res 2000;156:33-41. doi: 10.1007/978-3-642-57054-4_5. PMID: 10802861

Recent systematic reviews

Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Composite EBV negative peripheral T-cell lymphoma and diffuse large B-cell lymphoma involving the ileum: a case report and a systematic review of the literature.
Abou-Elella AA, Nifong TP
Leuk Lymphoma 2006 Oct;47(10):2208-17. doi: 10.1080/10428190600763348. PMID: 17071497

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