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Anal Hidradenoma Papilliferum

MedGen UID:
474606
•Concept ID:
C3272973
•
Neoplastic Process
Synonym: Anal Papillary Hidradenoma

Definition

A benign neoplasm arising from the perianal sweat glands. It presents as a cystic nodular lesion and is characterized by the presence of cystic and papillary structures. The papillary structures contain connective tissue and are covered by two layers of epithelium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnal Hidradenoma Papilliferum

Recent clinical studies

Etiology

Syringocystadenoma Papilliferum of the Anogenital Area and Buttocks: A Report of 16 Cases, Including Human Papillomavirus Analysis and HRAS and BRAF V600 Mutation Studies.
Konstantinova AM, Kyrpychova L, Nemcova J, Sedivcova M, Bisceglia M, Kutzner H, Zamecnik M, Sehnalkova E, Pavlovsky M, Zateckova K, Shvernik S, Spurkova Z, Michal M, Kerl K, Kazakov DV
Am J Dermatopathol 2019 Apr;41(4):281-285. doi: 10.1097/DAD.0000000000001285. PMID: 30398985
Vulvar hidradenoma papilliferum (HP) is located on the sites of mammary-like anogenital glands (MLAGs): Analysis of the photographs of 52 tumors.
El-Khoury J, Renald MH, Plantier F, Avril MF, Moyal-Barracco M
J Am Acad Dermatol 2016 Aug;75(2):380-4. Epub 2016 Mar 2 doi: 10.1016/j.jaad.2016.01.034. PMID: 26944596

Diagnosis

Vulvar hidradenoma papilliferum (HP) is located on the sites of mammary-like anogenital glands (MLAGs): Analysis of the photographs of 52 tumors.
El-Khoury J, Renald MH, Plantier F, Avril MF, Moyal-Barracco M
J Am Acad Dermatol 2016 Aug;75(2):380-4. Epub 2016 Mar 2 doi: 10.1016/j.jaad.2016.01.034. PMID: 26944596
Hidradenoma Papilliferum: A Clinicopathologic Study of 264 Tumors From 261 Patients, With Emphasis on Mammary-Type Alterations.
Konstantinova AM, Michal M, Kacerovska D, Spagnolo DV, Stewart CJ, Kutzner H, Zelger B, Plaza JA, Denisjuk N, Hejda V, Shelekhova K, Bisceglia M, Danis D, Zamecnik M, Kerl K, Guenova E, Kazakov DV
Am J Dermatopathol 2016 Aug;38(8):598-607. doi: 10.1097/DAD.0000000000000495. PMID: 26863059
Anal phyllodes tumor in a male patient: a unique case presentation and literature review.
Ho SP, Tseng HH, King TM, Chow PC
Diagn Pathol 2013 Mar 26;8:49. doi: 10.1186/1746-1596-8-49. PMID: 23531415Free PMC Article
Large ulcerated perianal hidradenoma papilliferum in a young female.
Handa Y, Yamanaka N, Inagaki H, Tomita Y
Dermatol Surg 2003 Jul;29(7):790-2. doi: 10.1046/j.1524-4725.2003.29201.x. PMID: 12828711

Prognosis

Hidradenoma Papilliferum: A Clinicopathologic Study of 264 Tumors From 261 Patients, With Emphasis on Mammary-Type Alterations.
Konstantinova AM, Michal M, Kacerovska D, Spagnolo DV, Stewart CJ, Kutzner H, Zelger B, Plaza JA, Denisjuk N, Hejda V, Shelekhova K, Bisceglia M, Danis D, Zamecnik M, Kerl K, Guenova E, Kazakov DV
Am J Dermatopathol 2016 Aug;38(8):598-607. doi: 10.1097/DAD.0000000000000495. PMID: 26863059
Anal phyllodes tumor in a male patient: a unique case presentation and literature review.
Ho SP, Tseng HH, King TM, Chow PC
Diagn Pathol 2013 Mar 26;8:49. doi: 10.1186/1746-1596-8-49. PMID: 23531415Free PMC Article

Clinical prediction guides

Hidradenoma Papilliferum: A Clinicopathologic Study of 264 Tumors From 261 Patients, With Emphasis on Mammary-Type Alterations.
Konstantinova AM, Michal M, Kacerovska D, Spagnolo DV, Stewart CJ, Kutzner H, Zelger B, Plaza JA, Denisjuk N, Hejda V, Shelekhova K, Bisceglia M, Danis D, Zamecnik M, Kerl K, Guenova E, Kazakov DV
Am J Dermatopathol 2016 Aug;38(8):598-607. doi: 10.1097/DAD.0000000000000495. PMID: 26863059
Anal phyllodes tumor in a male patient: a unique case presentation and literature review.
Ho SP, Tseng HH, King TM, Chow PC
Diagn Pathol 2013 Mar 26;8:49. doi: 10.1186/1746-1596-8-49. PMID: 23531415Free PMC Article
Large ulcerated perianal hidradenoma papilliferum in a young female.
Handa Y, Yamanaka N, Inagaki H, Tomita Y
Dermatol Surg 2003 Jul;29(7):790-2. doi: 10.1046/j.1524-4725.2003.29201.x. PMID: 12828711

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