U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Necrotizing sialometaplasia

MedGen UID:
48659
Concept ID:
C0037033
Disease or Syndrome
Synonyms: Necrotizing Sialometaplasia; Necrotizing Sialometaplasias; Sialometaplasia, Necrotizing; Sialometaplasias, Necrotizing
SNOMED CT: Necrotizing sialometaplasia (109769000)
 
Monarch Initiative: MONDO:0006864

Definition

A benign, inflammatory, variably ulcerated, occasionally bilateral, self-healing lesion of the minor salivary glands that is often confused clinically and histologically with carcinoma. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNecrotizing sialometaplasia

Professional guidelines

PubMed

Dadfarnia T, Mohammed BS, Eltorky MA
Ann Diagn Pathol 2012 Jun;16(3):171-6. Epub 2011 Dec 24 doi: 10.1016/j.anndiagpath.2011.08.011. PMID: 22197541

Recent clinical studies

Etiology

Braxton DR, Nickleach DC, Liu Y, Farris AB 3rd
Virchows Arch 2014 Aug;465(2):135-43. Epub 2014 May 27 doi: 10.1007/s00428-014-1590-x. PMID: 24863247Free PMC Article
Gilowski Ł, Wiench R, Polakiewicz-Gilowska A, Dwornicka K
Am J Otolaryngol 2014 May-Jun;35(3):400-1. Epub 2014 Mar 11 doi: 10.1016/j.amjoto.2014.03.001. PMID: 24667056
Suresh L, Aguirre A
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 Sep;104(3):385-90. Epub 2006 Dec 4 doi: 10.1016/j.tripleo.2006.08.012. PMID: 17142073
Arduino PG, Carrozzo M, Pentenero M, Bertolusso G, Gandolfo S
Minerva Stomatol 2006 May;55(5):249-70. PMID: 16688102
Penner CR, Thompson LD
Ear Nose Throat J 2003 Jul;82(7):493-4. PMID: 12955830

Diagnosis

Lott Limbach A, Chute DJ
Head Neck Pathol 2023 Mar;17(1):119-131. Epub 2023 Mar 16 doi: 10.1007/s12105-023-01534-0. PMID: 36928740Free PMC Article
Philipone EM, Peters SM
Oral Maxillofac Surg Clin North Am 2023 May;35(2):219-226. Epub 2023 Feb 15 doi: 10.1016/j.coms.2022.10.001. PMID: 36805903
Medeiros MRS, Barros CCDS, Miguel MCDC, da Silveira ÉJD, de Oliveira PT
Stomatologija 2022;24(2):56-60. PMID: 37140239
Ledesma-Montes C, Garcés-Ortíz M, Salcido-García JF, Hernández-Flores F
Quintessence Int 2015 Jan;46(1):67-72. doi: 10.3290/j.qi.a32633. PMID: 25191669
Carlson DL
Arch Pathol Lab Med 2009 May;133(5):692-8. doi: 10.5858/133.5.692. PMID: 19415943

Therapy

Abdalla-Aslan R, Frid H, Totri A, Akrish S, Merhav G, Rachmiel A
Quintessence Int 2020;51(6):496-501. doi: 10.3290/j.qi.a44146. PMID: 32080687
Janner SF, Suter VG, Altermatt HJ, Reichart PA, Bornstein MM
Quintessence Int 2014 May;45(5):431-7. doi: 10.3290/j.qi.a31543. PMID: 24634907
Arduino PG, Carrozzo M, Pentenero M, Bertolusso G, Gandolfo S
Minerva Stomatol 2006 May;55(5):249-70. PMID: 16688102
Keogh PV, O'Regan E, Toner M, Flint S
Br Dent J 2004 Jan 24;196(2):79-81. doi: 10.1038/sj.bdj.4810892. PMID: 14739958
Nilsen R, Bernhoft CH, Gilhuus-Moe O
Int J Oral Surg 1978 Dec;7(6):580-4. doi: 10.1016/s0300-9785(78)80077-5. PMID: 103857

Prognosis

Gadkaree SK, Fuller JC, Sadow PM, Deschler DG, Richmon JD
Ear Nose Throat J 2019 Oct-Nov;98(9):NP138-NP141. Epub 2019 Apr 9 doi: 10.1177/0145561319840826. PMID: 30966809Free PMC Article
Stodulski D, Majewska H, Skálová A, Mikaszewski B, Biernat W, Stankiewicz C
Eur Arch Otorhinolaryngol 2016 Nov;273(11):3937-3942. Epub 2016 Apr 21 doi: 10.1007/s00405-016-4048-8. PMID: 27101824Free PMC Article
Ledesma-Montes C, Garcés-Ortíz M, Salcido-García JF, Hernández-Flores F
Quintessence Int 2015 Jan;46(1):67-72. doi: 10.3290/j.qi.a32633. PMID: 25191669
Capelli M, Caputo V, Saginario V, Susicky A, Castellani C, Jankovic C, Berardi A, La Guardia M, Berardi C
Minerva Stomatol 2010 Jul-Aug;59(7-8):437-43. PMID: 20842082
Penner CR, Thompson LD
Ear Nose Throat J 2003 Jul;82(7):493-4. PMID: 12955830

Clinical prediction guides

Néri JDSV, Silva VPD, Ramalho LMP, De Castro LP, Santos JND
Dermatol Online J 2020 Dec 15;26(12) PMID: 33423426
Stodulski D, Majewska H, Skálová A, Mikaszewski B, Biernat W, Stankiewicz C
Eur Arch Otorhinolaryngol 2016 Nov;273(11):3937-3942. Epub 2016 Apr 21 doi: 10.1007/s00405-016-4048-8. PMID: 27101824Free PMC Article
Allon I, Kaplan I, Allon DM, Vered H, Shlomi B, Hirshberg A
Oral Dis 2014 Jul;20(5):440-5. Epub 2013 Jul 10 doi: 10.1111/odi.12149. PMID: 23837804
Suresh L, Aguirre A
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 Sep;104(3):385-90. Epub 2006 Dec 4 doi: 10.1016/j.tripleo.2006.08.012. PMID: 17142073
Fowler CB, Brannon RB
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000 May;89(5):600-9. doi: 10.1067/moe.2000.105943. PMID: 10807718

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...