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Arthropod-borne viral encephalitis, vector unknown

MedGen UID:
4933
•Concept ID:
C0014055
•
Disease or Syndrome
Synonyms: Arboviral Encephalitides; Arboviral Encephalitis; Arbovirus Encephalitides; Arbovirus Encephalitis; Arthropod Borne Encephalitis; Arthropod Borne Viral Encephalitis; Arthropod-Borne Encephalitides; Arthropod-Borne Encephalitis; Arthropod-Borne Viral Encephalitides; Arthropod-Borne Viral Encephalitis; Encephalitis, Arboviral; Encephalitis, Arbovirus; Encephalitis, Arthropod Borne; Encephalitis, Arthropod-Borne; Encephalitis, Arthropod-Borne Viral; Encephalitis, Epidemic; Epidemic Encephalitides; Epidemic Encephalitis; Viral Encephalitis, Arthropod Borne; Viral Encephalitis, Arthropod-Borne
SNOMED CT: Epidemic encephalitis (186498004); Arbovirus encephalitis (192687008); Arboviral encephalitis (192687008); Arthropod-borne viral encephalitis, vector unknown (285756005)

Definition

A term that may be used to describe encephalitis characterized by sleepiness, which is likely due to a viral cause. [from NCI]

Professional guidelines

PubMed

Dynamics of the emergence and establishment of a newly dominant genotype of Japanese encephalitis virus throughout Asia.
Schuh AJ, Ward MJ, Leigh Brown AJ, Barrett AD
J Virol 2014 Apr;88(8):4522-32. Epub 2014 Feb 5 doi: 10.1128/JVI.02686-13. PMID: 24501419Free PMC Article
Emergence of Japanese encephalitis virus genotype V in the Republic of Korea.
Takhampunya R, Kim HC, Tippayachai B, Kengluecha A, Klein TA, Lee WJ, Grieco J, Evans BP
Virol J 2011 Sep 23;8:449. doi: 10.1186/1743-422X-8-449. PMID: 21943222Free PMC Article

Recent clinical studies

Etiology

Cellular co-infections of West Nile virus and Usutu virus influence virus growth kinetics.
Körsten C, Reemtsma H, Ziegler U, Fischer S, Tews BA, Groschup MH, Silaghi C, Vasic A, Holicki CM
Virol J 2023 Oct 13;20(1):234. doi: 10.1186/s12985-023-02206-9. PMID: 37833787Free PMC Article
The knowns and unknowns of West Nile virus in Europe: what did we learn from the 2018 outbreak?
Camp JV, Nowotny N
Expert Rev Anti Infect Ther 2020 Feb;18(2):145-154. Epub 2020 Jan 14 doi: 10.1080/14787210.2020.1713751. PMID: 31914833
Exploring the Reservoir Hosts of Tick-Borne Encephalitis Virus.
Michelitsch A, Wernike K, Klaus C, Dobler G, Beer M
Viruses 2019 Jul 22;11(7) doi: 10.3390/v11070669. PMID: 31336624Free PMC Article
Ongoing and emerging arbovirus threats in Europe.
Barzon L
J Clin Virol 2018 Oct;107:38-47. Epub 2018 Aug 23 doi: 10.1016/j.jcv.2018.08.007. PMID: 30176404
Emerging and re-emerging infectious diseases.
Feldmann H, Czub M, Jones S, Dick D, Garbutt M, Grolla A, Artsob H
Med Microbiol Immunol 2002 Oct;191(2):63-74. Epub 2002 Sep 3 doi: 10.1007/s00430-002-0122-5. PMID: 12410344

Diagnosis

Tick-borne encephalitis virus IgG antibody surveillance: vaccination- and infection-induced seroprevalences, south-western Germany, 2021.
Euringer K, Girl P, Kaier K, Peilstöcker J, Schmidt M, Müller-Steinhardt M, Rauscher B, Bressau E, Kern WV, Dobler G, Borde JP
Euro Surveill 2023 Mar;28(12) doi: 10.2807/1560-7917.ES.2023.28.12.2200408. PMID: 36951789Free PMC Article
Detection of tick-borne encephalitis virus in ear tissue and dried blood spots from naturally infected wild rodents.
Pascoe EL, de Vries A, Esser HJ, Koenraadt CJM, Sprong H
Parasit Vectors 2023 Mar 16;16(1):103. doi: 10.1186/s13071-023-05717-0. PMID: 36927723Free PMC Article
Exploring the Reservoir Hosts of Tick-Borne Encephalitis Virus.
Michelitsch A, Wernike K, Klaus C, Dobler G, Beer M
Viruses 2019 Jul 22;11(7) doi: 10.3390/v11070669. PMID: 31336624Free PMC Article
Acute Human Inkoo and Chatanga Virus Infections, Finland.
Putkuri N, Kantele A, Levanov L, Kivistö I, Brummer-Korvenkontio M, Vaheri A, Vapalahti O
Emerg Infect Dis 2016 May;22(5):810-7. doi: 10.3201/eid2205.151015. PMID: 27088268Free PMC Article
Tick-borne encephalitis: a disease neglected by travel medicine.
Haditsch M, Kunze U
Travel Med Infect Dis 2013 Sep-Oct;11(5):295-300. Epub 2013 Jul 31 doi: 10.1016/j.tmaid.2013.07.003. PMID: 23916617

Therapy

Tick-borne encephalitis: a disease neglected by travel medicine.
Haditsch M, Kunze U
Travel Med Infect Dis 2013 Sep-Oct;11(5):295-300. Epub 2013 Jul 31 doi: 10.1016/j.tmaid.2013.07.003. PMID: 23916617
A survey of US travelers to Asia to assess compliance with recommendations for the use of Japanese encephalitis vaccine.
Duffy MR, Reed C, Edelson PJ, Blumensaadt S, Crocker K, Griggs A, Biggerstaff BJ, Delorey MJ, Hayes EB, Fischer M
J Travel Med 2013 May-Jun;20(3):165-70. Epub 2013 Mar 8 doi: 10.1111/jtm.12020. PMID: 23577862Free PMC Article
Passive prophylaxis with permethrin-treated tents reduces mosquito bites among North American summer campers.
Boulware DR, Beisang AA 3rd
Wilderness Environ Med 2005 Spring;16(1):9-15. doi: 10.1580/1080-6032(2005)16[9:ppwptr]2.0.co;2. PMID: 15813141Free PMC Article

Prognosis

Tick-borne encephalitis virus IgG antibody surveillance: vaccination- and infection-induced seroprevalences, south-western Germany, 2021.
Euringer K, Girl P, Kaier K, Peilstöcker J, Schmidt M, Müller-Steinhardt M, Rauscher B, Bressau E, Kern WV, Dobler G, Borde JP
Euro Surveill 2023 Mar;28(12) doi: 10.2807/1560-7917.ES.2023.28.12.2200408. PMID: 36951789Free PMC Article
Revealing new tick-borne encephalitis virus foci by screening antibodies in sheep milk.
Wallenhammar A, Lindqvist R, Asghar N, Gunaltay S, Fredlund H, Davidsson Å, Andersson S, Överby AK, Johansson M
Parasit Vectors 2020 Apr 8;13(1):185. doi: 10.1186/s13071-020-04030-4. PMID: 32268924Free PMC Article
Acute Human Inkoo and Chatanga Virus Infections, Finland.
Putkuri N, Kantele A, Levanov L, Kivistö I, Brummer-Korvenkontio M, Vaheri A, Vapalahti O
Emerg Infect Dis 2016 May;22(5):810-7. doi: 10.3201/eid2205.151015. PMID: 27088268Free PMC Article
Tick-borne encephalitis virus in ticks detached from humans and follow-up of serological and clinical response.
Lindblom P, Wilhelmsson P, Fryland L, Sjöwall J, Haglund M, Matussek A, Ernerudh J, Vene S, Nyman D, Andreassen A, Forsberg P, Lindgren PE
Ticks Tick Borne Dis 2014 Feb;5(1):21-8. Epub 2013 Oct 25 doi: 10.1016/j.ttbdis.2013.07.009. PMID: 24275477
Differential salivary gland transcript expression profile in Ixodes scapularis nymphs upon feeding or flavivirus infection.
McNally KL, Mitzel DN, Anderson JM, Ribeiro JM, Valenzuela JG, Myers TG, Godinez A, Wolfinbarger JB, Best SM, Bloom ME
Ticks Tick Borne Dis 2012 Feb;3(1):18-26. Epub 2012 Jan 2 doi: 10.1016/j.ttbdis.2011.09.003. PMID: 22309855Free PMC Article

Clinical prediction guides

RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology.
He X, Ashbrook AW, Du Y, Wu J, Hoffmann HH, Zhang C, Xia L, Peng YC, Tumas KC, Singh BK, Qi CF, Myers TG, Long CA, Liu C, Wang R, Rice CM, Su XZ
Proc Natl Acad Sci U S A 2020 Aug 11;117(32):19465-19474. Epub 2020 Jul 24 doi: 10.1073/pnas.2006492117. PMID: 32709745Free PMC Article
Revealing new tick-borne encephalitis virus foci by screening antibodies in sheep milk.
Wallenhammar A, Lindqvist R, Asghar N, Gunaltay S, Fredlund H, Davidsson Å, Andersson S, Överby AK, Johansson M
Parasit Vectors 2020 Apr 8;13(1):185. doi: 10.1186/s13071-020-04030-4. PMID: 32268924Free PMC Article
The knowns and unknowns of West Nile virus in Europe: what did we learn from the 2018 outbreak?
Camp JV, Nowotny N
Expert Rev Anti Infect Ther 2020 Feb;18(2):145-154. Epub 2020 Jan 14 doi: 10.1080/14787210.2020.1713751. PMID: 31914833
Epidemiology of West Nile Virus in the Eastern Mediterranean region: A systematic review.
Eybpoosh S, Fazlalipour M, Baniasadi V, Pouriayevali MH, Sadeghi F, Ahmadi Vasmehjani A, Karbalaie Niya MH, Hewson R, Salehi-Vaziri M
PLoS Negl Trop Dis 2019 Jan;13(1):e0007081. Epub 2019 Jan 29 doi: 10.1371/journal.pntd.0007081. PMID: 30695031Free PMC Article
Tick-borne encephalitis virus in ticks detached from humans and follow-up of serological and clinical response.
Lindblom P, Wilhelmsson P, Fryland L, Sjöwall J, Haglund M, Matussek A, Ernerudh J, Vene S, Nyman D, Andreassen A, Forsberg P, Lindgren PE
Ticks Tick Borne Dis 2014 Feb;5(1):21-8. Epub 2013 Oct 25 doi: 10.1016/j.ttbdis.2013.07.009. PMID: 24275477

Recent systematic reviews

Arboviruses in Mammals in the Neotropics: A Systematic Review to Strengthen Epidemiological Monitoring Strategies and Conservation Medicine.
García-Romero C, Carrillo Bilbao GA, Navarro JC, Martin-Solano S, Saegerman C
Viruses 2023 Feb 1;15(2) doi: 10.3390/v15020417. PMID: 36851630Free PMC Article
Epidemiology of West Nile Virus in the Eastern Mediterranean region: A systematic review.
Eybpoosh S, Fazlalipour M, Baniasadi V, Pouriayevali MH, Sadeghi F, Ahmadi Vasmehjani A, Karbalaie Niya MH, Hewson R, Salehi-Vaziri M
PLoS Negl Trop Dis 2019 Jan;13(1):e0007081. Epub 2019 Jan 29 doi: 10.1371/journal.pntd.0007081. PMID: 30695031Free PMC Article

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