U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Menometrorrhagia

MedGen UID:
534930
•Concept ID:
C0232943
•
Sign or Symptom
Synonyms: Intermenstrual heavy bleeding; Metromenorrhagia
SNOMED CT: Menometrorrhagia (314631008); Metromenorrhagia (314631008); Intermenstrual heavy bleeding (351814001)
 
HPO: HP:0400008

Definition

Prolonged/excessive menses and bleeding at irregular intervals. [from HPO]

Professional guidelines

PubMed

The Rationale for Photobiomodulation Therapy of Vaginal Tissue for Treatment of Genitourinary Syndrome of Menopause: An Analysis of Its Mechanism of Action, and Current Clinical Outcomes.
Lanzafame RJ, de la Torre S, Leibaschoff GH
Photobiomodul Photomed Laser Surg 2019 Jul;37(7):395-407. Epub 2019 Jun 17 doi: 10.1089/photob.2019.4618. PMID: 31210575Free PMC Article
Place of ulipristal acetate in the management of uterine fibroids: Preoperative treatment or sequential treatment?
Pourcelot AG, Capmas P, Fernandez H
J Gynecol Obstet Hum Reprod 2017 Mar;46(3):249-254. Epub 2017 Feb 3 doi: 10.1016/j.jogoh.2017.02.001. PMID: 28403922
The management of iron deficiency in menometrorrhagia.
Palacios S
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1126-30. doi: 10.3109/09513590.2012.636916. PMID: 22182056

Recent clinical studies

Therapy

The treatment with Levonorgestrel Releasing Intrauterine System (LNG-IUS) in patients affected by menometrorrhagia, dysmenorrhea and adenomimyois: clinical and ultrasonographic reports.
Costanzi F, De Marco MP, Colombrino C, Ciancia M, Torcia F, Ruscito I, Bellati F, Frega A, Cozza G, Caserta D
Eur Rev Med Pharmacol Sci 2021 May;25(9):3432-3439. doi: 10.26355/eurrev_202105_25823. PMID: 34002816
The management of iron deficiency in menometrorrhagia.
Palacios S
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1126-30. doi: 10.3109/09513590.2012.636916. PMID: 22182056
Current and future medical treatments for menometrorrhagia during the premenopause.
Bouchard P
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1120-5. doi: 10.3109/09513590.2012.638754. PMID: 22182055
GnRH-agonists in fertility preservation.
Blumenfeld Z
Curr Opin Endocrinol Diabetes Obes 2008 Dec;15(6):523-8. doi: 10.1097/MED.0b013e32831a46e9. PMID: 18971681
Clinical decision making regarding leiomyomata: what we need in the next millenium.
Haney AF
Environ Health Perspect 2000 Oct;108 Suppl 5:835-9. doi: 10.1289/ehp.00108s5835. PMID: 11035991

Prognosis

Mesonephric-Like Adenocarcinomas a Rare Tumor: The Importance of Diagnosis.
Restaino S, Pellecchia G, Tulisso A, Paglietti C, Orsaria M, Andreetta C, Poletto E, Arcieri M, Martina MD, Biasioli A, Mariuzzi L, Driul L, Scambia G, Vizzielli G
Int J Environ Res Public Health 2022 Nov 4;19(21) doi: 10.3390/ijerph192114451. PMID: 36361332Free PMC Article
Thyroid Function Screening in Children and Adolescents With Mood and Anxiety Disorders.
Luft MJ, Aldrich SL, Poweleit E, Prows CA, Martin LJ, DelBello MP, Keeshin BR, Ramsey LB, Strawn JR
J Clin Psychiatry 2019 Aug 6;80(5) doi: 10.4088/JCP.18m12626. PMID: 31390496
Endocervical Atypical Polypoid Adenomyoma.
Protopapas A, Sotiropoulou M, Athanasiou S, Loutradis D
J Minim Invasive Gynecol 2016 Jan;23(1):130-2. Epub 2015 Aug 22 doi: 10.1016/j.jmig.2015.08.879. PMID: 26304721
Risk factors for adenomyosis, leiomyoma and concurrent adenomyosis and leiomyoma.
Güzel Aİ, Akselim B, Erkılınç S, Kokanalı K, Tokmak A, Dolmuş B, Doğanay M
J Obstet Gynaecol Res 2015 Jun;41(6):932-7. Epub 2015 Feb 6 doi: 10.1111/jog.12635. PMID: 25656315
Uterine leiomyoma causing menometrorrhagia with a concomitant mature teratoma in a 15-year-old child: a case report and review of the literature.
Naiditch JA, Milad MP, Rowell EE
J Pediatr Surg 2011 Oct;46(10):E33-6. doi: 10.1016/j.jpedsurg.2011.06.031. PMID: 22008360

Clinical prediction guides

Histological assessment of endometrial polyps resected by hysteroscopy.
Tekin S, Ocal A, Sisman E, Bilginer C, Cetin A
Eur Rev Med Pharmacol Sci 2024 Apr;28(8):3241-3250. doi: 10.26355/eurrev_202404_36052. PMID: 38708482
The treatment with Levonorgestrel Releasing Intrauterine System (LNG-IUS) in patients affected by menometrorrhagia, dysmenorrhea and adenomimyois: clinical and ultrasonographic reports.
Costanzi F, De Marco MP, Colombrino C, Ciancia M, Torcia F, Ruscito I, Bellati F, Frega A, Cozza G, Caserta D
Eur Rev Med Pharmacol Sci 2021 May;25(9):3432-3439. doi: 10.26355/eurrev_202105_25823. PMID: 34002816
Thyroid Function Screening in Children and Adolescents With Mood and Anxiety Disorders.
Luft MJ, Aldrich SL, Poweleit E, Prows CA, Martin LJ, DelBello MP, Keeshin BR, Ramsey LB, Strawn JR
J Clin Psychiatry 2019 Aug 6;80(5) doi: 10.4088/JCP.18m12626. PMID: 31390496
Place of ulipristal acetate in the management of uterine fibroids: Preoperative treatment or sequential treatment?
Pourcelot AG, Capmas P, Fernandez H
J Gynecol Obstet Hum Reprod 2017 Mar;46(3):249-254. Epub 2017 Feb 3 doi: 10.1016/j.jogoh.2017.02.001. PMID: 28403922
Current and future medical treatments for menometrorrhagia during the premenopause.
Bouchard P
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1120-5. doi: 10.3109/09513590.2012.638754. PMID: 22182055

Recent systematic reviews

The efficacy and safety of JAK inhibitors in patients with adult-onset still's disease: A meta-analysis and systematic review.
Liao J, Tang Q, Xie X, Zhou B, Li F, Li S
Int Immunopharmacol 2024 Aug 20;137:112451. Epub 2024 Jun 12 doi: 10.1016/j.intimp.2024.112451. PMID: 38870881
A systematic review: endometriosis presenting with ascites.
Gungor T, Kanat-Pektas M, Ozat M, Zayifoglu Karaca M
Arch Gynecol Obstet 2011 Mar;283(3):513-8. Epub 2010 Sep 7 doi: 10.1007/s00404-010-1664-1. PMID: 20821226

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...