U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Menometrorrhagia

MedGen UID:
534930
•Concept ID:
C0232943
•
Sign or Symptom
Synonyms: Intermenstrual heavy bleeding; Metromenorrhagia
SNOMED CT: Menometrorrhagia (314631008); Metromenorrhagia (314631008); Intermenstrual heavy bleeding (351814001)
 
HPO: HP:0400008

Definition

Prolonged/excessive menses and bleeding at irregular intervals. [from HPO]

Professional guidelines

PubMed

The treatment with Levonorgestrel Releasing Intrauterine System (LNG-IUS) in patients affected by menometrorrhagia, dysmenorrhea and adenomimyois: clinical and ultrasonographic reports.
Costanzi F, De Marco MP, Colombrino C, Ciancia M, Torcia F, Ruscito I, Bellati F, Frega A, Cozza G, Caserta D
Eur Rev Med Pharmacol Sci 2021 May;25(9):3432-3439. doi: 10.26355/eurrev_202105_25823. PMID: 34002816
The Rationale for Photobiomodulation Therapy of Vaginal Tissue for Treatment of Genitourinary Syndrome of Menopause: An Analysis of Its Mechanism of Action, and Current Clinical Outcomes.
Lanzafame RJ, de la Torre S, Leibaschoff GH
Photobiomodul Photomed Laser Surg 2019 Jul;37(7):395-407. Epub 2019 Jun 17 doi: 10.1089/photob.2019.4618. PMID: 31210575Free PMC Article
The management of iron deficiency in menometrorrhagia.
Palacios S
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1126-30. doi: 10.3109/09513590.2012.636916. PMID: 22182056

Recent clinical studies

Etiology

PALM-COEIN Nomenclature for Abnormal Uterine Bleeding.
Deneris A
J Midwifery Womens Health 2016 May;61(3):376-9. Epub 2016 Mar 11 doi: 10.1111/jmwh.12440. PMID: 26969858
Endocervical Atypical Polypoid Adenomyoma.
Protopapas A, Sotiropoulou M, Athanasiou S, Loutradis D
J Minim Invasive Gynecol 2016 Jan;23(1):130-2. Epub 2015 Aug 22 doi: 10.1016/j.jmig.2015.08.879. PMID: 26304721
Menometrorrhagia during the premenopause: an overview.
Donnez J
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1114-9. doi: 10.3109/09513590.2012.637341. PMID: 22182054
A systematic review: endometriosis presenting with ascites.
Gungor T, Kanat-Pektas M, Ozat M, Zayifoglu Karaca M
Arch Gynecol Obstet 2011 Mar;283(3):513-8. Epub 2010 Sep 7 doi: 10.1007/s00404-010-1664-1. PMID: 20821226
Intrauterine devices.
Burkman RT
Curr Opin Obstet Gynecol 1991 Aug;3(4):482-5. PMID: 1878504

Diagnosis

Abnormal uterine bleeding in adolescents.
Kabra R, Fisher M
Curr Probl Pediatr Adolesc Health Care 2022 May;52(5):101185. Epub 2022 May 4 doi: 10.1016/j.cppeds.2022.101185. PMID: 35525787
Pathology and Pathogenesis of Adenomyosis.
Antero MF, Ayhan A, Segars J, Shih IM
Semin Reprod Med 2020 May;38(2-03):108-118. Epub 2020 Oct 20 doi: 10.1055/s-0040-1718922. PMID: 33080632Free PMC Article
Menometrorrhagia during the premenopause: an overview.
Donnez J
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1114-9. doi: 10.3109/09513590.2012.637341. PMID: 22182054
Bernard-Soulier syndrome: an inherited platelet disorder.
Pham A, Wang J
Arch Pathol Lab Med 2007 Dec;131(12):1834-6. doi: 10.5858/2007-131-1834-BSAIPD. PMID: 18081445
Hysteroscopy and adenocarcinoma.
Mencaglia L
Obstet Gynecol Clin North Am 1995 Sep;22(3):573-9. PMID: 8524538

Therapy

The treatment with Levonorgestrel Releasing Intrauterine System (LNG-IUS) in patients affected by menometrorrhagia, dysmenorrhea and adenomimyois: clinical and ultrasonographic reports.
Costanzi F, De Marco MP, Colombrino C, Ciancia M, Torcia F, Ruscito I, Bellati F, Frega A, Cozza G, Caserta D
Eur Rev Med Pharmacol Sci 2021 May;25(9):3432-3439. doi: 10.26355/eurrev_202105_25823. PMID: 34002816
The management of iron deficiency in menometrorrhagia.
Palacios S
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1126-30. doi: 10.3109/09513590.2012.636916. PMID: 22182056
Current and future medical treatments for menometrorrhagia during the premenopause.
Bouchard P
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1120-5. doi: 10.3109/09513590.2012.638754. PMID: 22182055
GnRH-agonists in fertility preservation.
Blumenfeld Z
Curr Opin Endocrinol Diabetes Obes 2008 Dec;15(6):523-8. doi: 10.1097/MED.0b013e32831a46e9. PMID: 18971681
Menometrorrhagia and tachyarrhythmia after using oral and topical ginseng.
Kabalak AA, Soyal OB, Urfalioglu A, Saracoglu F, Gogus N
J Womens Health (Larchmt) 2004 Sep;13(7):830-3. doi: 10.1089/jwh.2004.13.830. PMID: 15385077

Prognosis

Mesonephric-Like Adenocarcinomas a Rare Tumor: The Importance of Diagnosis.
Restaino S, Pellecchia G, Tulisso A, Paglietti C, Orsaria M, Andreetta C, Poletto E, Arcieri M, Martina MD, Biasioli A, Mariuzzi L, Driul L, Scambia G, Vizzielli G
Int J Environ Res Public Health 2022 Nov 4;19(21) doi: 10.3390/ijerph192114451. PMID: 36361332Free PMC Article
Oncocytic adrenocortical neoplasm with undetermined malignant potential and autonomous cortisol secretion.
San Juan MD, Lagamayo D, Carnate J, Joven MH
BMJ Case Rep 2022 Apr 20;15(4) doi: 10.1136/bcr-2021-248525. PMID: 35444021Free PMC Article
Critical iron deficiency anemia with record low hemoglobin: a case report.
Chai AL, Huang OY, Rakočević R, Chung P
J Med Case Rep 2021 Sep 13;15(1):472. doi: 10.1186/s13256-021-03024-9. PMID: 34517883Free PMC Article
Thyroid Function Screening in Children and Adolescents With Mood and Anxiety Disorders.
Luft MJ, Aldrich SL, Poweleit E, Prows CA, Martin LJ, DelBello MP, Keeshin BR, Ramsey LB, Strawn JR
J Clin Psychiatry 2019 Aug 6;80(5) doi: 10.4088/JCP.18m12626. PMID: 31390496
Endocervical Atypical Polypoid Adenomyoma.
Protopapas A, Sotiropoulou M, Athanasiou S, Loutradis D
J Minim Invasive Gynecol 2016 Jan;23(1):130-2. Epub 2015 Aug 22 doi: 10.1016/j.jmig.2015.08.879. PMID: 26304721

Clinical prediction guides

The treatment with Levonorgestrel Releasing Intrauterine System (LNG-IUS) in patients affected by menometrorrhagia, dysmenorrhea and adenomimyois: clinical and ultrasonographic reports.
Costanzi F, De Marco MP, Colombrino C, Ciancia M, Torcia F, Ruscito I, Bellati F, Frega A, Cozza G, Caserta D
Eur Rev Med Pharmacol Sci 2021 May;25(9):3432-3439. doi: 10.26355/eurrev_202105_25823. PMID: 34002816
Thyroid Function Screening in Children and Adolescents With Mood and Anxiety Disorders.
Luft MJ, Aldrich SL, Poweleit E, Prows CA, Martin LJ, DelBello MP, Keeshin BR, Ramsey LB, Strawn JR
J Clin Psychiatry 2019 Aug 6;80(5) doi: 10.4088/JCP.18m12626. PMID: 31390496
Place of ulipristal acetate in the management of uterine fibroids: Preoperative treatment or sequential treatment?
Pourcelot AG, Capmas P, Fernandez H
J Gynecol Obstet Hum Reprod 2017 Mar;46(3):249-254. Epub 2017 Feb 3 doi: 10.1016/j.jogoh.2017.02.001. PMID: 28403922
Clinical and paraclinical study regarding the macro- and microscopic diagnosis of various anatomo-clinical forms of operated uterine fibromyoma.
Vaniova Klimentova D, Brăila AD, Simionescu C, Ilie I, Brăila MB
Rom J Morphol Embryol 2012;53(2):369-73. PMID: 22732808
Current and future medical treatments for menometrorrhagia during the premenopause.
Bouchard P
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1120-5. doi: 10.3109/09513590.2012.638754. PMID: 22182055

Recent systematic reviews

A systematic review: endometriosis presenting with ascites.
Gungor T, Kanat-Pektas M, Ozat M, Zayifoglu Karaca M
Arch Gynecol Obstet 2011 Mar;283(3):513-8. Epub 2010 Sep 7 doi: 10.1007/s00404-010-1664-1. PMID: 20821226

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...