U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Eyelid retraction

MedGen UID:
536147
Concept ID:
C0234665
Finding
Synonyms: Abnormal retraction of eyelid; Lid Retraction; Lid retraction; Retraction of eyelid
SNOMED CT: Lid retraction (14520009); Abnormal retraction of eyelid (43854003); Retraction of eyelid (14520009)
 
HPO: HP:0500043

Definition

With the eyes in primary position, the sclera is visible above the superior corneal limbus. [from HPO]

Conditions with this feature

Levator-medial rectus synkinesis
MedGen UID:
320592
Concept ID:
C1835403
Disease or Syndrome
Oculomotor-levator synkinesis (OCLEVS) is characterized by abnormal eyelid elevation or retraction during ipsilateral adduction. The disorder most likely results from aberrant innervation of extraocular muscles by the oculomotor nerve (cranial nerve III). Normally, the levator muscle is served by the superior branch of CN3 and the medial rectus muscle is served by the inferior branch of CN3. The clinical features suggest synkinesis between the medial rectus and levator muscle branches. The disorder can be classified as a congenital cranial dysinnervation disorder (CCDD) and also shows features of congenital fibrosis of the extraocular muscles (CFEOM; see 135700) (summary by Pang et al., 1986 and Khan et al., 2004) See also oculomotor-abducens synkinesis (OCABSN; 619215), caused by mutation in the ACKR3 gene (610376) on chromosome 2q37.

Professional guidelines

PubMed

Yu CY, Ford RL, Wester ST, Shriver EM
Indian J Ophthalmol 2022 Jul;70(7):2335-2345. doi: 10.4103/ijo.IJO_3217_21. PMID: 35791115Free PMC Article
Singh R, Davoudi S, Ness S
Graefes Arch Clin Exp Ophthalmol 2022 Aug;260(8):2399-2416. Epub 2022 Mar 12 doi: 10.1007/s00417-022-05607-8. PMID: 35278125Free PMC Article
Park E, Lewis K, Alghoul MS
Aesthet Surg J 2017 Jul 1;37(7):743-754. doi: 10.1093/asj/sjx003. PMID: 28333254

Recent clinical studies

Etiology

Wong MB, Maamari RN, Couch SM
Orbit 2022 Aug;41(4):452-456. Epub 2021 May 25 doi: 10.1080/01676830.2021.1931352. PMID: 34030599
Steinsapir KD, Steinsapir S
Facial Plast Surg Clin North Am 2021 May;29(2):291-300. Epub 2021 Apr 24 doi: 10.1016/j.fsc.2021.01.006. PMID: 33906761
Olayanju JA, Griepentrog GJ, Mohney BG
J AAPOS 2019 Aug;23(4):213.e1-213.e4. Epub 2019 Jun 20 doi: 10.1016/j.jaapos.2019.03.004. PMID: 31229605Free PMC Article
Homer N, Fay A
Otolaryngol Clin North Am 2018 Dec;51(6):1107-1118. Epub 2018 Aug 28 doi: 10.1016/j.otc.2018.07.007. PMID: 30170698
Kotlus B, Schwarcz RM
Clin Plast Surg 2015 Jan;42(1):73-7. Epub 2014 Oct 11 doi: 10.1016/j.cps.2014.09.006. PMID: 25440743

Diagnosis

Dutton JJ
Ophthalmic Plast Reconstr Surg 2018 Jul/Aug;34(4S Suppl 1):S7-S12. doi: 10.1097/IOP.0000000000001122. PMID: 29870437
Chambers CB, Moe KS
Facial Plast Surg Clin North Am 2017 Feb;25(1):25-36. doi: 10.1016/j.fsc.2016.08.007. PMID: 27888891
Cruz AA, Ribeiro SF, Garcia DM, Akaishi PM, Pinto CT
Surv Ophthalmol 2013 Jan-Feb;58(1):63-76. doi: 10.1016/j.survophthal.2012.02.007. PMID: 23217588
Alexandrakis G, Saunders RA
Ophthalmol Clin North Am 2001 Sep;14(3):407-17. doi: 10.1016/s0896-1549(05)70238-8. PMID: 11705140
Yeatts RP
Med Clin North Am 1995 Jan;79(1):195-209. doi: 10.1016/s0025-7125(16)30092-x. PMID: 7808092

Therapy

Patel A, Wang Y, Massry GG
Facial Plast Surg Clin North Am 2019 Nov;27(4):425-434. Epub 2019 Aug 30 doi: 10.1016/j.fsc.2019.07.014. PMID: 31587762
Berens AM, Akkina SR, Patel SA
Curr Opin Otolaryngol Head Neck Surg 2017 Aug;25(4):258-264. doi: 10.1097/MOO.0000000000000375. PMID: 28509671
Chambers CB, Moe KS
Facial Plast Surg Clin North Am 2017 Feb;25(1):25-36. doi: 10.1016/j.fsc.2016.08.007. PMID: 27888891
Ribeiro SF, Shekhovtsova M, Duarte AF, Velasco Cruz AA
Ophthalmic Plast Reconstr Surg 2016 May-Jun;32(3):161-9. doi: 10.1097/IOP.0000000000000613. PMID: 26784547
Scott IU, Siatkowski MR
Semin Ophthalmol 1999 Jun;14(2):52-61. doi: 10.3109/08820539909056064. PMID: 10758212

Prognosis

Ueland HO, Neset MT, Methlie P, Ueland GÅ, Pakdel F, Rødahl E
Ophthalmic Plast Reconstr Surg 2023 Dec 1;39(6S):S19-S28. Epub 2023 Dec 4 doi: 10.1097/IOP.0000000000002466. PMID: 38054982Free PMC Article
Olejarz M, Szczepanek-Parulska E, Ostałowska-Klockiewicz A, Antosik P, Sawicka-Gutaj N, Helak-Łapaj C, Stopa M, Ruchala M
Front Endocrinol (Lausanne) 2023;14:1083321. Epub 2023 Mar 1 doi: 10.3389/fendo.2023.1083321. PMID: 36936165Free PMC Article
Wang Y, Holds JB, Douglas RS, Massry GG
Facial Plast Surg Clin North Am 2021 May;29(2):275-289. Epub 2021 Apr 24 doi: 10.1016/j.fsc.2021.01.005. PMID: 33906760
Olayanju JA, Griepentrog GJ, Mohney BG
J AAPOS 2019 Aug;23(4):213.e1-213.e4. Epub 2019 Jun 20 doi: 10.1016/j.jaapos.2019.03.004. PMID: 31229605Free PMC Article
Kim KH, Baek JS, Lee S, Lee JH, Choi HS, Kim SJ, Jang JW
Korean J Ophthalmol 2017 Aug;31(4):290-298. Epub 2017 Jul 4 doi: 10.3341/kjo.2016.0059. PMID: 28682021Free PMC Article

Clinical prediction guides

Olejarz M, Szczepanek-Parulska E, Ostałowska-Klockiewicz A, Antosik P, Sawicka-Gutaj N, Helak-Łapaj C, Stopa M, Ruchala M
Front Endocrinol (Lausanne) 2023;14:1083321. Epub 2023 Mar 1 doi: 10.3389/fendo.2023.1083321. PMID: 36936165Free PMC Article
Coban I, Derin O, Sirinturk S, Pinar Y, Govsa F
Aesthetic Plast Surg 2023 Jun;47(3):1059-1066. Epub 2023 Mar 6 doi: 10.1007/s00266-023-03297-z. PMID: 36877228
Wasser LM, Roditi E, Weiss AR, Weill Y, Koslowsky M, Zadok D, Hanhart J, Magal I
Graefes Arch Clin Exp Ophthalmol 2022 Jun;260(6):2023-2028. Epub 2022 Jan 7 doi: 10.1007/s00417-021-05422-7. PMID: 34994840
Ionescu IC, van Trotsenburg PAS, Paridaens D, Tanck M, Mooij CF, Cagienard E, Kalmann R, Pakdel F, van der Meeren S, Saeed P
Acta Ophthalmol 2022 Sep;100(6):e1340-e1348. Epub 2021 Dec 23 doi: 10.1111/aos.15084. PMID: 34951116
Ozzello DJ, Dallalzadeh LO, Liu CY
Orbit 2022 Oct;41(5):539-546. Epub 2021 Jun 1 doi: 10.1080/01676830.2021.1933081. PMID: 34060414

Recent systematic reviews

Rafizadeh SM, Mirghorbani M, Tavakoli M, Haydar AA
Semin Ophthalmol 2024 Jan;39(1):40-59. Epub 2023 Dec 27 doi: 10.1080/08820538.2023.2273850. PMID: 37904540
McGrath LA, Hardy TG, McNab AA
Graefes Arch Clin Exp Ophthalmol 2020 Sep;258(9):1999-2006. Epub 2020 Apr 6 doi: 10.1007/s00417-020-04660-5. PMID: 32253504
Park E, Lewis K, Alghoul MS
Aesthet Surg J 2017 Jul 1;37(7):743-754. doi: 10.1093/asj/sjx003. PMID: 28333254
Bradley EA, Gower EW, Bradley DJ, Meyer DR, Cahill KV, Custer PL, Holck DE, Woog JJ
Ophthalmology 2008 Feb;115(2):398-409. doi: 10.1016/j.ophtha.2007.10.028. PMID: 18082885

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...