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Enostosis

MedGen UID:
539306
•Concept ID:
C0265512
•
Disease or Syndrome
Synonym: Bone island
SNOMED CT: Enostosis (782164008); Bone island (782164008)

Definition

An osteoma that develops in the medullary cavity of the bone. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEnostosis

Recent clinical studies

Etiology

Dense bone islands in pediatric patients: a case series study.
Alfahad S, Alostad M, Dunkley S, Anand P, Harvey S, Monteiro J
Eur Arch Paediatr Dent 2021 Aug;22(4):751-757. Epub 2021 Jan 10 doi: 10.1007/s40368-020-00596-w. PMID: 33423206Free PMC Article
Bone Tumors: Benign Bone Tumors.
Lam Y
FP Essent 2020 Jun;493:11-21. PMID: 32573182
Primary bone tumors and pseudotumors of the lumbosacral spine.
Leone A, Costantini A, Guglielmi G, Settecasi C, Priolo F
Rays 2000 Jan-Mar;25(1):89-103. PMID: 10967637
From the archives of the AFIP. Primary tumors of the spine: radiologic pathologic correlation.
Murphey MD, Andrews CL, Flemming DJ, Temple HT, Smith WS, Smirniotopoulos JG
Radiographics 1996 Sep;16(5):1131-58. doi: 10.1148/radiographics.16.5.8888395. PMID: 8888395
Sclerosing bone dysplasias--a target-site approach.
Greenspan A
Skeletal Radiol 1991;20(8):561-83. doi: 10.1007/BF01106087. PMID: 1776023

Diagnosis

Osteoid Tumors of Bone.
Amini B, Valenzuela RF, Bird JE, Haygood TM
Semin Ultrasound CT MR 2021 Apr;42(2):134-149. Epub 2020 Aug 29 doi: 10.1053/j.sult.2020.08.020. PMID: 33814101
Bone Tumors: Benign Bone Tumors.
Lam Y
FP Essent 2020 Jun;493:11-21. PMID: 32573182
Primary tumors of the spine.
Orguc S, Arkun R
Semin Musculoskelet Radiol 2014 Jul;18(3):280-99. Epub 2014 Jun 4 doi: 10.1055/s-0034-1375570. PMID: 24896744
Primary tumors of the spine.
Flemming DJ, Murphey MD, Carmichael BB, Bernard SA
Semin Musculoskelet Radiol 2000;4(3):299-320. doi: 10.1055/s-2000-9340. PMID: 11371321
Osteoid-producing tumors of bone.
White LM, Kandel R
Semin Musculoskelet Radiol 2000;4(1):25-43. doi: 10.1055/s-2000-6853. PMID: 11061690

Therapy

Bone island and leprosy.
Carpintero P, García-Frasquet A, Tarradas E, Logroño C, Carrascal A, Carreto A
Skeletal Radiol 1998 Jun;27(6):330-33. doi: 10.1007/s002560050391. PMID: 9677650
A radiographic survey of periapical jawbone lesions.
Marmary Y, Kutiner G
Oral Surg Oral Med Oral Pathol 1986 Apr;61(4):405-8. doi: 10.1016/0030-4220(86)90427-5. PMID: 3458152

Prognosis

Accuracy of CT Attenuation Measurement for Differentiating Treated Osteoblastic Metastases From Enostoses.
Elangovan SM, Sebro R
AJR Am J Roentgenol 2018 Mar;210(3):615-620. Epub 2018 Jan 11 doi: 10.2214/AJR.17.18638. PMID: 29323547
Osteoid-producing tumors of bone.
White LM, Kandel R
Semin Musculoskelet Radiol 2000;4(1):25-43. doi: 10.1055/s-2000-6853. PMID: 11061690
Bone island: scintigraphic findings and their clinical application.
Greenspan A, Stadalnik RC
Can Assoc Radiol J 1995 Oct;46(5):368-79. PMID: 7552829
Intracortical and subperiosteal lesion of unknown etiology.
Jackson RP, Reckling FW
Clin Orthop Relat Res 1978 Jan-Feb;(130):260-2. PMID: 639398

Clinical prediction guides

Radiographic assessment of incidental bone lesions of the proximal humerus: a prevalence study.
Kara M, Bayram S, Kocazeybek E, Demirtaş G
Acta Radiol 2024 Oct;65(10):1246-1251. Epub 2024 Aug 30 doi: 10.1177/02841851241275058. PMID: 39211957
Bone islands incidentally detected on computed tomography: frequency of enostosis and differentiation from untreated osteoblastic metastases based on CT attenuation value.
Sala F, Dapoto A, Morzenti C, Firetto MC, Valle C, Tomasoni A, Sironi S
Br J Radiol 2019 Nov;92(1103):20190249. Epub 2019 Sep 9 doi: 10.1259/bjr.20190249. PMID: 31469323Free PMC Article
Bone island and leprosy.
Carpintero P, García-Frasquet A, Tarradas E, Logroño C, Carrascal A, Carreto A
Skeletal Radiol 1998 Jun;27(6):330-33. doi: 10.1007/s002560050391. PMID: 9677650
Bone island: scintigraphic findings and their clinical application.
Greenspan A, Stadalnik RC
Can Assoc Radiol J 1995 Oct;46(5):368-79. PMID: 7552829

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