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Hypersensitivity reaction mediated by immune complex

MedGen UID:
549647
•Concept ID:
C0301918
•
Disease or Syndrome
Synonyms: Gell and Coombs reaction type III; Hypersensitivity reaction type III; Type 3 Hypersensitivity Reaction; Type III Hypersensitivity; Type III Hypersensitivity Reaction; Type III reaction
SNOMED CT: Hypersensitivity reaction mediated by immune complex (83699005); Type III reaction (83699005); Gell and Coombs reaction type III (83699005); Hypersensitivity reaction type III (83699005)

Definition

A hypersensitivity reaction resulting from the deposition of antigen-antibody immune complexes in tissues, which trigger activation of the complement system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypersensitivity reaction mediated by immune complex

Professional guidelines

PubMed

Updated Review on Treatment of Atopic Dermatitis.
Armario-Hita JC, Galán-Gutiérrez M, Dodero-Anillo JM, Carrascosa JM, Ruiz-Villaverde R
J Investig Allergol Clin Immunol 2023 Jun;33(3):158-167. doi: 10.18176/jiaci.0906. PMID: 37318771
Atopic dermatitis: new insight into the etiology, pathogenesis, diagnosis and novel treatment strategies.
Mandlik DS, Mandlik SK
Immunopharmacol Immunotoxicol 2021 Apr;43(2):105-125. Epub 2021 Feb 28 doi: 10.1080/08923973.2021.1889583. PMID: 33645388
Understanding the key issues in the treatment of uncontrolled persistent asthma with type 2 inflammation.
Busse WW, Kraft M, Rabe KF, Deniz Y, Rowe PJ, Ruddy M, Castro M
Eur Respir J 2021 Aug;58(2) Epub 2021 Aug 5 doi: 10.1183/13993003.03393-2020. PMID: 33542055Free PMC Article

Recent clinical studies

Diagnosis

Severe serum sickness reaction to oral and intramuscular penicillin.
Clark BM, Kotti GH, Shah AD, Conger NG
Pharmacotherapy 2006 May;26(5):705-8. doi: 10.1592/phco.26.5.705. PMID: 16718943

Therapy

Severe serum sickness reaction to oral and intramuscular penicillin.
Clark BM, Kotti GH, Shah AD, Conger NG
Pharmacotherapy 2006 May;26(5):705-8. doi: 10.1592/phco.26.5.705. PMID: 16718943

Clinical prediction guides

Severe serum sickness reaction to oral and intramuscular penicillin.
Clark BM, Kotti GH, Shah AD, Conger NG
Pharmacotherapy 2006 May;26(5):705-8. doi: 10.1592/phco.26.5.705. PMID: 16718943

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