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Malignant histiocytic disorder

MedGen UID:: 5567
•Concept ID:: C0019613
•: Neoplastic Process

Synonyms:	Disorder, Malignant Histiocytic; Disorders, Malignant Histiocytic; Histiocytic Disorder, Malignant; Histiocytic Disorders, Malignant; Malignant Histiocytic Disorder; Malignant Histiocytic Disorders
SNOMED CT:	Malignant histiocytic disorder (127070008)

Definition

Distinctive neoplastic disorders of histiocytes. Included are malignant neoplasms of MACROPHAGES and DENDRITIC CELLS. [from MeSH]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMalignant histiocytic disorder

Abnormal immune system morphology
- Abnormal cellular immune system morphology
  - Abnormal leukocyte morphology
    - Abnormal myeloid leukocyte morphology
      - Abnormal macrophage morphology
        Histiocytosis
        Malignant histiocytic disorder
        Follicular dendritic cell sarcoma
        Conventional Follicular Dendritic Cell Sarcoma
        EBV-Positive Inflammatory Follicular Dendritic Cell Sarcoma
        EBV-Positive Inflammatory Follicular Dendritic Cell/Fibroblastic Reticular Cell Tumor of the Digestive System
        Head and Neck Follicular Dendritic Cell Sarcoma
        Thyroid Gland Follicular Dendritic Cell Sarcoma
        Histiocytic sarcoma
        Central Nervous System Histiocytic Sarcoma
        Interdigitating dendritic cell sarcoma
        Langerhans cell sarcoma

Professional guidelines

PubMed

Histiocytic neoplasms: a brief review and differential diagnosis.

Yamada R, Komohara Y
J Clin Exp Hematop 2024;64(3):156-165. doi: 10.3960/jslrt.24031. PMID: 39343608 Free PMC Article

Treatment of Langerhans Cell Histiocytosis and Histiocytic Disorders: A Focus on MAPK Pathway Inhibitors.

Geerlinks AV, Abla O
Paediatr Drugs 2023 Jul;25(4):399-409. Epub 2023 May 19 doi: 10.1007/s40272-023-00569-8. PMID: 37204611

Pathogenesis, diagnosis, and management of Kikuchi-Fujimoto disease.

Deaver D, Horna P, Cualing H, Sokol L
Cancer Control 2014 Oct;21(4):313-21. doi: 10.1177/107327481402100407. PMID: 25310212

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