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Non-Ossifying Fibroma

MedGen UID:
569529
Concept ID:
C0334067
Neoplastic Process
Synonyms: Fibrous cortical defect of bone; Metaphyseal fibrous defect; Non-ossifying fibroma
SNOMED CT: Metaphyseal fibrous defect (80415005); Non-ossifying fibroma (80415005); Fibrous cortical defect of bone (80415005)

Definition

A tumor histologically indistinguishable from, but larger than, benign fibrous histiocytoma of bone. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNon-Ossifying Fibroma

Professional guidelines

PubMed

Andreacchio A, Alberghina F, Testa G, Canavese F
Eur J Orthop Surg Traumatol 2018 Feb;28(2):291-297. Epub 2017 Aug 17 doi: 10.1007/s00590-017-2028-3. PMID: 28819829
Baschang A, von Laer L
Eur J Pediatr Surg 1991 Aug;1(4):207-9. doi: 10.1055/s-2008-1042489. PMID: 1931839

Recent clinical studies

Etiology

Emori M, Tsuchie H, Teramoto A, Shimizu J, Mizushima E, Murahashi Y, Nagasawa H, Miyakoshi N, Yamashita T
BMC Musculoskelet Disord 2022 Apr 22;23(1):378. doi: 10.1186/s12891-022-05330-9. PMID: 35459158Free PMC Article
Hartmann W, Harder D, Baumhoer D
Surg Pathol Clin 2021 Dec;14(4):695-706. Epub 2021 Oct 7 doi: 10.1016/j.path.2021.06.010. PMID: 34742488
Jamshidi K, Motaghi P, Bagherifard A, Eigi M, Al-Baseesee HH, Mirzaei A
J Orthop Sci 2021 Jul;26(4):655-659. Epub 2020 Aug 17 doi: 10.1016/j.jos.2020.06.010. PMID: 32819790
Herget GW, Mauer D, Krauß T, El Tayeh A, Uhl M, Südkamp NP, Hauschild O
BMC Musculoskelet Disord 2016 Apr 5;17:147. doi: 10.1186/s12891-016-1004-0. PMID: 27044378Free PMC Article
Choi Y, Kwak JM, Chung SH, Jung GH, Kim JD
Clin Orthop Surg 2014 Mar;6(1):72-9. Epub 2014 Feb 14 doi: 10.4055/cios.2014.6.1.72. PMID: 24605192Free PMC Article

Diagnosis

Cleven AHG, Schreuder WH, Groen E, de Lange J, Briaire-de Bruijn IH, Bovée JVMG
Virchows Arch 2022 Oct;481(4):671-675. Epub 2022 May 25 doi: 10.1007/s00428-022-03341-4. PMID: 35612673Free PMC Article
Hartmann W, Harder D, Baumhoer D
Surg Pathol Clin 2021 Dec;14(4):695-706. Epub 2021 Oct 7 doi: 10.1016/j.path.2021.06.010. PMID: 34742488
Eyesan SU, Katchy AU, Idowu OO, Adesina SA, Ayandele BO, Ano-Edward U
Niger Postgrad Med J 2018 Apr-Jun;25(2):126-129. doi: 10.4103/npmj.npmj_60_18. PMID: 30027926
Bowers LM, Cohen DM, Bhattacharyya I, Pettigrew JC Jr, Stavropoulos MF
Head Neck Pathol 2013 Jun;7(2):203-10. Epub 2012 Sep 25 doi: 10.1007/s12105-012-0399-7. PMID: 23008139Free PMC Article
Mankin HJ, Trahan CA, Fondren G, Mankin CJ
Chir Organi Mov 2009 May;93(1):1-7. Epub 2009 Apr 29 doi: 10.1007/s12306-009-0016-4. PMID: 19711155

Therapy

Tariq MU, Umer M, Khan Z, Saeed J, Siddiqui MA, Din NU
Ann Diagn Pathol 2020 Apr;45:151479. Epub 2020 Feb 14 doi: 10.1016/j.anndiagpath.2020.151479. PMID: 32088577
Andreacchio A, Alberghina F, Testa G, Canavese F
Eur J Orthop Surg Traumatol 2018 Feb;28(2):291-297. Epub 2017 Aug 17 doi: 10.1007/s00590-017-2028-3. PMID: 28819829
Ceroni D, Dayer R, De Coulon G, Kaelin A
Musculoskelet Surg 2011 Aug;95(2):107-14. Epub 2011 Mar 16 doi: 10.1007/s12306-011-0115-x. PMID: 21409501
Sanatkumar S, Rajagopalan N, Mallikarjunaswamy B, Srinivasalu S, Sudhir NP, Usha K
J Orthop Surg (Hong Kong) 2005 Apr;13(1):83-7. doi: 10.1177/230949900501300116. PMID: 15872408

Prognosis

Ventura L, Petrella E, Piciucchi S, Cilli E, Luiselli D, Feeney RNM, Traversari M
Virchows Arch 2021 Dec;479(6):1255-1261. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03192-5. PMID: 34462806Free PMC Article
Chaib B, Malhotra K, Khoo M, Saifuddin A
Br J Radiol 2021 Sep 1;94(1125):20201341. Epub 2021 Jul 28 doi: 10.1259/bjr.20201341. PMID: 34319796Free PMC Article
Herget GW, Mauer D, Krauß T, El Tayeh A, Uhl M, Südkamp NP, Hauschild O
BMC Musculoskelet Disord 2016 Apr 5;17:147. doi: 10.1186/s12891-016-1004-0. PMID: 27044378Free PMC Article
Yanagisawa M, Kakizaki H, Okada K, Torigoe T, Kusumi T
Ups J Med Sci 2013 Mar;118(1):23-8. Epub 2012 Oct 4 doi: 10.3109/03009734.2012.724731. PMID: 23033898Free PMC Article
Chrcanovic BR, Albanese AL, Freire-Maia B, Nunes FC, Souza PE, Gomez RS
Oral Maxillofac Surg 2011 Dec;15(4):233-7. Epub 2010 Jul 28 doi: 10.1007/s10006-010-0244-7. PMID: 20665061

Clinical prediction guides

Cleven AHG, Schreuder WH, Groen E, de Lange J, Briaire-de Bruijn IH, Bovée JVMG
Virchows Arch 2022 Oct;481(4):671-675. Epub 2022 May 25 doi: 10.1007/s00428-022-03341-4. PMID: 35612673Free PMC Article
Ventura L, Petrella E, Piciucchi S, Cilli E, Luiselli D, Feeney RNM, Traversari M
Virchows Arch 2021 Dec;479(6):1255-1261. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03192-5. PMID: 34462806Free PMC Article
Baněčková M, Agaimy A
Ann Diagn Pathol 2020 Jun;46:151510. Epub 2020 Apr 2 doi: 10.1016/j.anndiagpath.2020.151510. PMID: 32252013
Eyesan SU, Katchy AU, Idowu OO, Adesina SA, Ayandele BO, Ano-Edward U
Niger Postgrad Med J 2018 Apr-Jun;25(2):126-129. doi: 10.4103/npmj.npmj_60_18. PMID: 30027926
Lysenko N, Sharmazanova Y, Voronzhev I, Sorochan A, Kolomiychenko Y
Georgian Med News 2017 Jan;(262):4-14. PMID: 28252420

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