Disorder of excessive somnolence

MedGen UID:: 5699
•Concept ID:: C0020524
•: Mental or Behavioral Dysfunction

Synonyms:	Disorders of Excessive Somnolence; DOES (Disorders of Excessive Somnolence); DOESs (Disorders of Excessive Somnolence); Excessive Somnolence Disorder; Excessive Somnolence Disorders; Hypersomnolence Disorder; Hypersomnolence Disorders; Somnolence Disorder, Excessive
SNOMED CT:	Disorder of excessive somnolence (194439006)

Definition

Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320) [from MeSH]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVDisorder of excessive somnolence

Disease
- Disorder by Site
  - Disorder of nervous system
    - Disorders, Sleep Wake
      - Dyssomnia
        Sleep Disorders, Intrinsic
        Disorder of excessive somnolence
        Idiopathic hypersomnia
        Kleine-Levin syndrome
        Narcolepsy
        Cataplexy
        Cataplexy and narcolepsy
        Narcolepsy without cataplexy

Professional guidelines

PubMed

European guideline and expert statements on the management of narcolepsy in adults and children.

Bassetti CLA, Kallweit U, Vignatelli L, Plazzi G, Lecendreux M, Baldin E, Dolenc-Groselj L, Jennum P, Khatami R, Manconi M, Mayer G, Partinen M, Pollmächer T, Reading P, Santamaria J, Sonka K, Dauvilliers Y, Lammers GJ
J Sleep Res 2021 Dec;30(6):e13387. Epub 2021 Jun 25 doi: 10.1111/jsr.13387. PMID: 34173288

Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment.

Bassetti CLA, Adamantidis A, Burdakov D, Han F, Gay S, Kallweit U, Khatami R, Koning F, Kornum BR, Lammers GJ, Liblau RS, Luppi PH, Mayer G, Pollmächer T, Sakurai T, Sallusto F, Scammell TE, Tafti M, Dauvilliers Y
Nat Rev Neurol 2019 Sep;15(9):519-539. Epub 2019 Jul 19 doi: 10.1038/s41582-019-0226-9. PMID: 31324898

Narcolepsy: Diagnosis and management.

Golden EC, Lipford MC
Cleve Clin J Med 2018 Dec;85(12):959-969. doi: 10.3949/ccjm.85a.17086. PMID: 30526757

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