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Benign neoplasm of tongue

MedGen UID:
57573
•Concept ID:
C0153933
•
Neoplastic Process
Synonyms: Benign Neoplasm of the Tongue; benign neoplasm of the tongue; Benign Neoplasm of Tongue; benign neoplasm of tongue; Benign Tongue Neoplasm; benign tongue neoplasm; Benign Tongue Tumor; benign tongue tumor; benign tongue tumour; Benign Tumor of the Tongue; benign tumor of the tongue; Benign tumor of tongue; Benign Tumor of Tongue; benign tumor of tongue; benign tumour of the tongue; benign tumour of tongue; tongue benign neoplasm; Tongue Neoplasm, Benign; tongue neoplasm, benign
SNOMED CT: Benign tumor of tongue (92443005); Benign neoplasm of tongue (92443005)
 
Monarch Initiative: MONDO:0021476

Definition

A neoplasm that arises from the tongue and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of tongue

Professional guidelines

PubMed

Pathogenesis and Treatment of Pancreatic Cancer Related Pain.
Lohse I, Brothers SP
Anticancer Res 2020 Apr;40(4):1789-1796. doi: 10.21873/anticanres.14133. PMID: 32234867Free PMC Article
Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management.
Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A
J Formos Med Assoc 2018 Sep;117(9):756-765. Epub 2018 Feb 19 doi: 10.1016/j.jfma.2018.01.021. PMID: 29472048
Diagnosis and Treatment of Pituitary Adenomas: A Review.
Molitch ME
JAMA 2017 Feb 7;317(5):516-524. doi: 10.1001/jama.2016.19699. PMID: 28170483

Recent clinical studies

Etiology

Ultrasound-assisted resection of oral tongue cancer.
Nilsson O, Knutsson J, Landström FJ, Magnuson A, von Beckerath M
Acta Otolaryngol 2022 Sep-Dec;142(9-12):743-748. Epub 2022 Dec 20 doi: 10.1080/00016489.2022.2153916. PMID: 36537851
Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis.
Matsuo K, Akiba J, Kusukawa J, Yano H
Am J Physiol Cell Physiol 2022 Dec 1;323(6):C1611-C1623. Epub 2022 Oct 17 doi: 10.1152/ajpcell.00098.2022. PMID: 36252129
Node Out, About It? Consideration of Adjuvant Treatment of Oral Tongue Cancer.
Hara JHL, Juloori A
Int J Radiat Oncol Biol Phys 2022 Mar 15;112(4):849. doi: 10.1016/j.ijrobp.2020.09.037. PMID: 35190052
Expression and significance of laminin receptor in squamous cell carcinoma of the tongue.
Matsuo K, Akiba J, Ogasawara S, Kondo R, Naito Y, Kusano H, Sanada S, Kakuma T, Kusukawa J, Yano H
J Oral Pathol Med 2022 Mar;51(3):263-271. Epub 2021 Oct 11 doi: 10.1111/jop.13247. PMID: 34581463
Tongue flap revisited.
Deshmukh A, Kannan S, Thakkar P, Chaukar D, Yadav P, D'Cruz A
J Cancer Res Ther 2013 Apr-Jun;9(2):215-8. doi: 10.4103/0973-1482.113354. PMID: 23771361

Diagnosis

Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis.
Matsuo K, Akiba J, Kusukawa J, Yano H
Am J Physiol Cell Physiol 2022 Dec 1;323(6):C1611-C1623. Epub 2022 Oct 17 doi: 10.1152/ajpcell.00098.2022. PMID: 36252129
Leukoplakia of the tongue.
Ohta K, Yoshimura H
Cleve Clin J Med 2020 Mar;87(3):133-134. doi: 10.3949/ccjm.87a.19087. PMID: 32127435
Transoral Robotic Surgery and the Unknown Primary.
Ofo E, Spiers H, Kim D, Duvvuri U
ORL J Otorhinolaryngol Relat Spec 2018;80(3-4):148-155. Epub 2018 Nov 12 doi: 10.1159/000490596. PMID: 30419564
Angiomyxolipoma of Tongue.
Bajpai M, Chandolia B, Arora M
J Coll Physicians Surg Pak 2017 Apr;27(4):252-253. PMID: 28492157
Angiokeratoma of Tongue.
Bakshi SS
J Pediatr Hematol Oncol 2017 Jul;39(5):407. doi: 10.1097/MPH.0000000000000748. PMID: 28060116

Therapy

Human papillomavirus vaccine efficacy against invasive, HPV-positive cancers: population-based follow-up of a cluster-randomised trial.
Lehtinen M, Lagheden C, Luostarinen T, Eriksson T, Apter D, Bly A, Gray P, Harjula K, Heikkilä K, Hokkanen M, Karttunen H, Kuortti M, Nieminen P, Nummela M, Paavonen J, Palmroth J, Petäjä T, Pukkala E, Soderlund-Strand A, Veivo U, Dillner J
BMJ Open 2021 Dec 30;11(12):e050669. doi: 10.1136/bmjopen-2021-050669. PMID: 35149535Free PMC Article
Do Gut Microbes Taste?
Leung R, Covasa M
Nutrients 2021 Jul 27;13(8) doi: 10.3390/nu13082581. PMID: 34444741Free PMC Article
Tongue microbiome of smokeless tobacco users.
Halboub E, Al-Ak'hali MS, Alamir AH, Homeida HE, Baraniya D, Chen T, Al-Hebshi NN
BMC Microbiol 2020 Jul 8;20(1):201. doi: 10.1186/s12866-020-01883-8. PMID: 32640977Free PMC Article
Radiotherapy versus transoral robotic surgery and neck dissection for oropharyngeal squamous cell carcinoma (ORATOR): an open-label, phase 2, randomised trial.
Nichols AC, Theurer J, Prisman E, Read N, Berthelet E, Tran E, Fung K, de Almeida JR, Bayley A, Goldstein DP, Hier M, Sultanem K, Richardson K, Mlynarek A, Krishnan S, Le H, Yoo J, MacNeil SD, Winquist E, Hammond JA, Venkatesan V, Kuruvilla S, Warner A, Mitchell S, Chen J, Corsten M, Johnson-Obaseki S, Eapen L, Odell M, Parker C, Wehrli B, Kwan K, Palma DA
Lancet Oncol 2019 Oct;20(10):1349-1359. Epub 2019 Aug 12 doi: 10.1016/S1470-2045(19)30410-3. PMID: 31416685
MRI in differentiation of benign and malignant tongue tumors.
Liu X, Cheng D, Wang W
Front Biosci (Landmark Ed) 2015 Jan 1;20(4):614-20. doi: 10.2741/4326. PMID: 25553468

Prognosis

Oral amyloidosis: an update.
Pontes FS, Ferreira GB, Fonseca FP, Ribeiro TF, Caldeira PC, Tavares TS, Bentes AP, Lopes MA, Silva TA, Lemos JG, Pontes HA
Med Oral Patol Oral Cir Bucal 2023 Jul 1;28(4):e341-e346. doi: 10.4317/medoral.25761. PMID: 37330968Free PMC Article
Ultrasound-assisted resection of oral tongue cancer.
Nilsson O, Knutsson J, Landström FJ, Magnuson A, von Beckerath M
Acta Otolaryngol 2022 Sep-Dec;142(9-12):743-748. Epub 2022 Dec 20 doi: 10.1080/00016489.2022.2153916. PMID: 36537851
Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis.
Matsuo K, Akiba J, Kusukawa J, Yano H
Am J Physiol Cell Physiol 2022 Dec 1;323(6):C1611-C1623. Epub 2022 Oct 17 doi: 10.1152/ajpcell.00098.2022. PMID: 36252129
Imaging Features of isolated hypoglossal nerve palsy.
Guarnizo A, Glikstein R, Torres C
J Neuroradiol 2020 Mar;47(2):136-150. Epub 2019 Apr 26 doi: 10.1016/j.neurad.2019.04.006. PMID: 31034896
Perineural Invasion and Perineural Tumor Spread in Head and Neck Cancer.
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546

Clinical prediction guides

Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis.
Matsuo K, Akiba J, Kusukawa J, Yano H
Am J Physiol Cell Physiol 2022 Dec 1;323(6):C1611-C1623. Epub 2022 Oct 17 doi: 10.1152/ajpcell.00098.2022. PMID: 36252129
Cribriform adenocarcinoma of the tongue and minor salivary glands: a systematic review of an uncommon clinicopathological entity.
De Luca P, Tassone D, de Campora L, Simone M, Marra P, Colacurcio V, Scarpa A, Costarelli L, Camaioni A
Eur Arch Otorhinolaryngol 2022 Jun;279(6):2719-2725. Epub 2021 Oct 23 doi: 10.1007/s00405-021-07140-6. PMID: 34687340
Tongue-coating microbiome as a cancer predictor: A scoping review.
Ali Mohammed MM, Al Kawas S, Al-Qadhi G
Arch Oral Biol 2021 Dec;132:105271. Epub 2021 Sep 27 doi: 10.1016/j.archoralbio.2021.105271. PMID: 34610507
Chondroma of the Tongue.
Dimitrijevic MV, Sopta J, Ivisevic TB, Dudvarski Z
J Craniofac Surg 2019 Jun;30(4):e315-e317. doi: 10.1097/SCS.0000000000005230. PMID: 30845089
Nodal metastases: predictive factors.
Kowalski LP, Medina JE
Otolaryngol Clin North Am 1998 Aug;31(4):621-37. doi: 10.1016/s0030-6665(05)70076-1. PMID: 9687325

Recent systematic reviews

Oral amyloidosis: an update.
Pontes FS, Ferreira GB, Fonseca FP, Ribeiro TF, Caldeira PC, Tavares TS, Bentes AP, Lopes MA, Silva TA, Lemos JG, Pontes HA
Med Oral Patol Oral Cir Bucal 2023 Jul 1;28(4):e341-e346. doi: 10.4317/medoral.25761. PMID: 37330968Free PMC Article
Oral and Maxillofacial Neuroendocrine Carcinoma: A Systematic Review.
Schuch LF, Schmidt TR, de Oliveira Zigmundo G, Kirschnick LB, Silveira FM, Martins MAT, Carlos R, Dos Santos JN, Fonseca FP, Vargas PA, Wagner VP, Martins MD
Head Neck Pathol 2022 Jun;16(2):525-537. Epub 2021 Dec 6 doi: 10.1007/s12105-021-01398-2. PMID: 34870796Free PMC Article
Swallowing exercises for head and neck cancer patients: A systematic review and meta-analysis of randomized control trials.
Banda KJ, Chu H, Kao CC, Voss J, Chiu HL, Chang PC, Chen R, Chou KR
Int J Nurs Stud 2021 Feb;114:103827. Epub 2020 Nov 11 doi: 10.1016/j.ijnurstu.2020.103827. PMID: 33352439
Human papillomavirus infection and oral squamous cell carcinoma - a systematic review.
Melo BAC, Vilar LG, Oliveira NR, Lima PO, Pinheiro MB, Domingueti CP, Pereira MC
Braz J Otorhinolaryngol 2021 May-Jun;87(3):346-352. Epub 2020 Nov 29 doi: 10.1016/j.bjorl.2020.10.017. PMID: 33339760Free PMC Article
Age and risk of recurrence in oral tongue squamous cell carcinoma: Systematic review.
Lenze NR, Farquhar DR, Dorismond C, Sheth S, Zevallos JP, Blumberg J, Lumley C, Patel S, Hackman T, Weissler MC, Yarbrough WG, Olshan AF, Zanation AM
Head Neck 2020 Dec;42(12):3755-3768. Epub 2020 Sep 11 doi: 10.1002/hed.26464. PMID: 32914472

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