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Cyst of the eyelid

MedGen UID:
57601
•Concept ID:
C0155218
•
Disease or Syndrome
Synonyms: Cyst of eyelid; Cyst of Eyelid; Cyst of the Eyelid; Eyelid bump; Eyelid Cyst; Eyelid mass; Lesion of the eyelid
SNOMED CT: Cyst of eyelid (46210008)
 
HPO: HP:0010604

Definition

Localized swelling of the eyelid due to blockage of the meibomian glands, usually caused by inflammation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCyst of the eyelid

Professional guidelines

PubMed

Sebaceous carcinoma: evidence-based clinical practice guidelines.
Owen JL, Kibbi N, Worley B, Kelm RC, Wang JV, Barker CA, Behshad R, Bichakjian CK, Bolotin D, Bordeaux JS, Bradshaw SH, Cartee TV, Chandra S, Cho NL, Choi JN, Council ML, Demirci H, Eisen DB, Esmaeli B, Golda N, Huang CC, Ibrahim SF, Jiang SB, Kim J, Kuzel TM, Lai SY, Lawrence N, Lee EH, Leitenberger JJ, Maher IA, Mann MW, Minkis K, Mittal BB, Nehal KS, Neuhaus IM, Ozog DM, Petersen B, Rotemberg V, Samant S, Samie FH, Servaes S, Shields CL, Shin TM, Sobanko JF, Somani AK, Stebbins WG, Thomas JR, Thomas VD, Tse DT, Waldman AH, Wong MK, Xu YG, Yu SS, Zeitouni NC, Ramsay T, Reynolds KA, Poon E, Alam M
Lancet Oncol 2019 Dec;20(12):e699-e714. doi: 10.1016/S1470-2045(19)30673-4. PMID: 31797796
Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critically Ill Patient.
Murray MJ, DeBlock H, Erstad B, Gray A, Jacobi J, Jordan C, McGee W, McManus C, Meade M, Nix S, Patterson A, Sands MK, Pino R, Tescher A, Arbour R, Rochwerg B, Murray CF, Mehta S
Crit Care Med 2016 Nov;44(11):2079-2103. doi: 10.1097/CCM.0000000000002027. PMID: 27755068
Differential Diagnosis of the Swollen Red Eyelid.
Carlisle RT, Digiovanni J
Am Fam Physician 2015 Jul 15;92(2):106-12. PMID: 26176369

Recent clinical studies

Etiology

Intramuscular Eyelid Myxoma.
Liu CK, Williamson JE 3rd, Milman T, Lally SE, Shields CL
Ophthalmic Plast Reconstr Surg 2022 Nov-Dec 01;38(6):e180-e183. Epub 2022 Jul 4 doi: 10.1097/IOP.0000000000002236. PMID: 35793663
Merkel cell carcinoma of the eyelid: A review.
North VS, Habib LA, Yoon MK
Surv Ophthalmol 2019 Sep-Oct;64(5):659-667. Epub 2019 Mar 11 doi: 10.1016/j.survophthal.2019.03.002. PMID: 30871952
Pathology of eyelid tumors.
Pe'er J
Indian J Ophthalmol 2016 Mar;64(3):177-90. doi: 10.4103/0301-4738.181752. PMID: 27146927Free PMC Article
Eyelid reconstruction.
Alghoul M, Pacella SJ, McClellan WT, Codner MA
Plast Reconstr Surg 2013 Aug;132(2):288e-302e. doi: 10.1097/PRS.0b013e3182958e6b. PMID: 23897357
Ptosis: causes, presentation, and management.
Finsterer J
Aesthetic Plast Surg 2003 May-Jun;27(3):193-204. Epub 2003 Aug 21 doi: 10.1007/s00266-003-0127-5. PMID: 12925861

Diagnosis

The lowly chalazion.
Kim ES, Afshin EE, Elahi E
Surv Ophthalmol 2023 Jul-Aug;68(4):784-793. Epub 2022 Nov 15 doi: 10.1016/j.survophthal.2022.11.002. PMID: 36395826
Collagenoma of the Eyelid.
Purgert RJ, Blandford AD, Schowalter MK, Piliang MP, Hwang CJ, Perry JD
Ophthalmic Plast Reconstr Surg 2019 Mar/Apr;35(2):e29-e30. doi: 10.1097/IOP.0000000000001298. PMID: 30624411Free PMC Article
Lymphoma of the eyelid.
Svendsen FH, Heegaard S
Surv Ophthalmol 2017 May-Jun;62(3):312-331. Epub 2016 Nov 26 doi: 10.1016/j.survophthal.2016.11.009. PMID: 27894880
Differential Diagnosis of the Swollen Red Eyelid.
Carlisle RT, Digiovanni J
Am Fam Physician 2015 Jul 15;92(2):106-12. PMID: 26176369
Caruncular dacryops.
Jakobiec FA, Roh M, Stagner AM, Yoon MK
Cornea 2015 Jan;34(1):107-9. doi: 10.1097/ICO.0000000000000287. PMID: 25357082

Therapy

Conjunctival Lymphoma.
McGrath LA, Ryan DA, Warrier SK, Coupland SE, Glasson WJ
Eye (Lond) 2023 Apr;37(5):837-848. Epub 2022 Jul 26 doi: 10.1038/s41433-022-02176-2. PMID: 35882984Free PMC Article
Common inflammatory and infectious conditions of the eyelid.
Gordon AA, Danek DJ, Phelps PO
Dis Mon 2020 Oct;66(10):101042. Epub 2020 Jul 1 doi: 10.1016/j.disamonth.2020.101042. PMID: 32622681
Pharmacotherapy and Immunotherapy of Conjunctival Tumors.
Midena E, Frizziero L, Parrozzani R
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):121-131. doi: 10.22608/APO.201751. PMID: 28399343
Upper eyelid reconstruction.
DiFrancesco LM, Codner MA, McCord CD
Plast Reconstr Surg 2004 Dec;114(7):98e-107e. doi: 10.1097/01.prs.0000142743.57711.48. PMID: 15577335
Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease.
Crist WM, Anderson JR, Meza JL, Fryer C, Raney RB, Ruymann FB, Breneman J, Qualman SJ, Wiener E, Wharam M, Lobe T, Webber B, Maurer HM, Donaldson SS
J Clin Oncol 2001 Jun 15;19(12):3091-102. doi: 10.1200/JCO.2001.19.12.3091. PMID: 11408506

Prognosis

Intramuscular Eyelid Myxoma.
Liu CK, Williamson JE 3rd, Milman T, Lally SE, Shields CL
Ophthalmic Plast Reconstr Surg 2022 Nov-Dec 01;38(6):e180-e183. Epub 2022 Jul 4 doi: 10.1097/IOP.0000000000002236. PMID: 35793663
What's New in Eyelid Tumors.
Silverman N, Shinder R
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):143-152. doi: 10.22608/APO.201701. PMID: 28399340
Lymphoma of the eyelid.
Svendsen FH, Heegaard S
Surv Ophthalmol 2017 May-Jun;62(3):312-331. Epub 2016 Nov 26 doi: 10.1016/j.survophthal.2016.11.009. PMID: 27894880
Eyelid reconstruction.
Alghoul M, Pacella SJ, McClellan WT, Codner MA
Plast Reconstr Surg 2013 Aug;132(2):288e-302e. doi: 10.1097/PRS.0b013e3182958e6b. PMID: 23897357
Sebaceous carcinoma.
Nelson BR, Hamlet KR, Gillard M, Railan D, Johnson TM
J Am Acad Dermatol 1995 Jul;33(1):1-15; quiz 16-8. doi: 10.1016/0190-9622(95)90001-2. PMID: 7601925

Clinical prediction guides

Conjunctival Lymphoma.
McGrath LA, Ryan DA, Warrier SK, Coupland SE, Glasson WJ
Eye (Lond) 2023 Apr;37(5):837-848. Epub 2022 Jul 26 doi: 10.1038/s41433-022-02176-2. PMID: 35882984Free PMC Article
Actinic Granuloma of the Conjunctiva: Case Series and Review of the Literature.
Magan T, Rapuano CJ, Ayres BD, Skeens HM, Goyal V, Heersink S, Meghpara BB, Syed ZA, Eagle RC Jr, Milman T
Am J Ophthalmol 2021 Sep;229:120-126. Epub 2021 Apr 22 doi: 10.1016/j.ajo.2021.04.006. PMID: 33895150
Cancers of the eye.
Maheshwari A, Finger PT
Cancer Metastasis Rev 2018 Dec;37(4):677-690. doi: 10.1007/s10555-018-9762-9. PMID: 30203109
Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin.
Martincorena I, Roshan A, Gerstung M, Ellis P, Van Loo P, McLaren S, Wedge DC, Fullam A, Alexandrov LB, Tubio JM, Stebbings L, Menzies A, Widaa S, Stratton MR, Jones PH, Campbell PJ
Science 2015 May 22;348(6237):880-6. doi: 10.1126/science.aaa6806. PMID: 25999502Free PMC Article
Nanofat grafting: basic research and clinical applications.
Tonnard P, Verpaele A, Peeters G, Hamdi M, Cornelissen M, Declercq H
Plast Reconstr Surg 2013 Oct;132(4):1017-1026. doi: 10.1097/PRS.0b013e31829fe1b0. PMID: 23783059

Recent systematic reviews

Holding back the tears: is there a role for marsupialisation?
Chiu SJ, Currie ZI, Tan JH
BMJ Open Ophthalmol 2022 Aug;7(1) doi: 10.1136/bmjophth-2022-000985. PMID: 36161857Free PMC Article
Sebaceous Carcinoma of the Eyelid: A Systematic Review and Meta-Analysis.
Desiato VM, Byun YJ, Nguyen SA, Thiers BH, Day TA
Dermatol Surg 2021 Jan 1;47(1):104-110. doi: 10.1097/DSS.0000000000002660. PMID: 33347004
A systematic review of ultrasound biomicroscopy use in pediatric ophthalmology.
Alexander JL, Wei L, Palmer J, Darras A, Levin MR, Berry JL, Ludeman E
Eye (Lond) 2021 Jan;35(1):265-276. Epub 2020 Sep 22 doi: 10.1038/s41433-020-01184-4. PMID: 32963311Free PMC Article
Pathophysiology, diagnosis, and management of glaucoma associated with Sturge-Weber syndrome.
Javaid U, Ali MH, Jamal S, Butt NH
Int Ophthalmol 2018 Feb;38(1):409-416. Epub 2017 Jan 7 doi: 10.1007/s10792-016-0412-3. PMID: 28064423
Divided nevus of the eyelid: review of embryology, pathology and treatment.
Desai SC, Walen S, Holds JB, Branham G
Am J Otolaryngol 2013 May-Jun;34(3):223-9. Epub 2013 Feb 4 doi: 10.1016/j.amjoto.2013.01.004. PMID: 23380310

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