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Ventricular septal aneurysm

MedGen UID:
576652
•Concept ID:
C0344954
•
Disease or Syndrome
Synonym: Ventricular septal dilatation
SNOMED CT: Ventricular septal aneurysm (253577002)
 
HPO: HP:0030957

Definition

A bowing (bulging to one side) of the interventricular septum of more than 15 mm on either side in adults and 5 mm in children during normal cardiac motion. [from HPO]

Professional guidelines

PubMed

Recent insights into pathophysiology and management of mechanical complications of myocardial infarction.
Fatehi Hassanabad A, Elbatarny M, Wong JVS, Kim A, Ali IS
Curr Opin Cardiol 2021 Sep 1;36(5):623-629. doi: 10.1097/HCO.0000000000000881. PMID: 34397468
Clinical utility of cardiovascular magnetic resonance in hypertrophic cardiomyopathy.
Maron MS
J Cardiovasc Magn Reson 2012 Feb 1;14(1):13. doi: 10.1186/1532-429X-14-13. PMID: 22296938Free PMC Article
Role of routine transthoracic echocardiography in evaluation and management of stroke.
Beattie JR, Cohen DJ, Manning WJ, Douglas PS
J Intern Med 1998 Apr;243(4):281-91. doi: 10.1046/j.1365-2796.1998.00300.x. PMID: 9627142

Recent clinical studies

Etiology

Group A streptococcus endocarditis in children: 2 cases and a review of the literature.
Ogura N, Tomari K, Takayama T, Tonegawa N, Okawa T, Matsuoka T, Nakayashiro M, Matsumora T
BMC Infect Dis 2019 Jan 31;19(1):102. doi: 10.1186/s12879-019-3736-6. PMID: 30704409Free PMC Article
A single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm.
Wang K, Wang X, Yu H, Liu X, Xing A, You Y
BMC Pregnancy Childbirth 2018 Jan 3;18(1):8. doi: 10.1186/s12884-017-1646-4. PMID: 29298686Free PMC Article
Transcatheter closure of perimembranous ventricular septal defects with the Amplatzer Vascular Plug-II.
Hua N, Aquino P, Owada CY
Cardiol Young 2016 Aug;26(6):1194-201. Epub 2015 Oct 26 doi: 10.1017/S1047951115002206. PMID: 26498904
Ventricular septal defect with secondary left ventricular-to-right atrial shunt is associated with a higher risk for infective endocarditis and a lower late chance of closure.
Wu MH, Wang JK, Lin MT, Wu ET, Lu FL, Chiu SN, Lue HC
Pediatrics 2006 Feb;117(2):e262-7. Epub 2006 Jan 17 doi: 10.1542/peds.2005-1255. PMID: 16418312
QRS axis in isolated perimembranous ventricular septal defect and influences of morphological factors on QRS axis.
Tutar HE, Atalay S, Türkay S, Imamoglu A
J Electrocardiol 2001 Jul;34(3):197-203. doi: 10.1054/jelc.2001.24763. PMID: 11455509

Diagnosis

Isolated Ventricular Septal Aneurysm: A Differential Diagnosis for a Right Sinus of Valsalva Aneurysm.
Assaf A, Berry R, Mantha Y, Zughaib M, Saba S
Am J Case Rep 2021 May 23;22:e930930. doi: 10.12659/AJCR.930930. PMID: 34023848Free PMC Article
Membranous septal aneurysm causing severe right ventricular outflow obstruction in an adult with trisomy 18.
Herron C, Forbes TJ, Kobayashi D
Cardiol Young 2021 Sep;31(9):1498-1499. Epub 2021 May 14 doi: 10.1017/S1047951121001931. PMID: 33985617
Management of Late-Presenting Congenital Combined Heart Defect - Bicuspid Aortic Valve and Ventricular Septal Aneurysm.
Groudeva VV, Atzev BG, Petkov DG
Am J Case Rep 2020 Mar 13;21:e919766. doi: 10.12659/AJCR.919766. PMID: 32165609Free PMC Article
Group A streptococcus endocarditis in children: 2 cases and a review of the literature.
Ogura N, Tomari K, Takayama T, Tonegawa N, Okawa T, Matsuoka T, Nakayashiro M, Matsumora T
BMC Infect Dis 2019 Jan 31;19(1):102. doi: 10.1186/s12879-019-3736-6. PMID: 30704409Free PMC Article
Congenital muscular ventricular septal aneurysm: report of four cases and review of the literature.
Nguyen TP, Srivastava S, Ko HH, Lai WW
Pediatr Cardiol 2008 Jan;29(1):40-4. Epub 2007 Sep 5 doi: 10.1007/s00246-007-9048-4. PMID: 17786376

Therapy

A case presentation of acquired membranous ventricular septum aneurysm as a rare delayed complication of ventricular septal defect repair surgery: 10-year follow-up.
Liu Z, Liang T, Jia S, Zhang W, Feng Y, Huang H
BMC Cardiovasc Disord 2023 Jul 12;23(1):346. doi: 10.1186/s12872-023-03361-1. PMID: 37438743Free PMC Article
Early Localized Ventricular Septal Aneurysm Formation in Acute Eosinophilic Myocarditis.
Fujimoto N, Sato T, Moriwaki K, Sugiura E, Nakamori S, Imanaka-Yoshida K, Ito M, Dohi K
Circ J 2019 Nov 25;83(12):2567. Epub 2019 Jul 23 doi: 10.1253/circj.CJ-19-0451. PMID: 31341138
Group A streptococcus endocarditis in children: 2 cases and a review of the literature.
Ogura N, Tomari K, Takayama T, Tonegawa N, Okawa T, Matsuoka T, Nakayashiro M, Matsumora T
BMC Infect Dis 2019 Jan 31;19(1):102. doi: 10.1186/s12879-019-3736-6. PMID: 30704409Free PMC Article
Transcatheter closure of perimembranous ventricular septal defects with the Amplatzer Vascular Plug-II.
Hua N, Aquino P, Owada CY
Cardiol Young 2016 Aug;26(6):1194-201. Epub 2015 Oct 26 doi: 10.1017/S1047951115002206. PMID: 26498904

Prognosis

Isolated Ventricular Septal Aneurysm: A Differential Diagnosis for a Right Sinus of Valsalva Aneurysm.
Assaf A, Berry R, Mantha Y, Zughaib M, Saba S
Am J Case Rep 2021 May 23;22:e930930. doi: 10.12659/AJCR.930930. PMID: 34023848Free PMC Article
Group A streptococcus endocarditis in children: 2 cases and a review of the literature.
Ogura N, Tomari K, Takayama T, Tonegawa N, Okawa T, Matsuoka T, Nakayashiro M, Matsumora T
BMC Infect Dis 2019 Jan 31;19(1):102. doi: 10.1186/s12879-019-3736-6. PMID: 30704409Free PMC Article
Two Cases of Prenatally Diagnosed Membranous and Muscular Ventricular Septal Aneurysms.
Ivanitskaya O, Andreeva E, Odegova N
J Ultrasound Med 2018 Apr;37(4):1039-1042. Epub 2017 Sep 29 doi: 10.1002/jum.14440. PMID: 28960425
Transcatheter closure of perimembranous ventricular septal defects with the Amplatzer Vascular Plug-II.
Hua N, Aquino P, Owada CY
Cardiol Young 2016 Aug;26(6):1194-201. Epub 2015 Oct 26 doi: 10.1017/S1047951115002206. PMID: 26498904
Importance of (perimembranous) ventricular septal aneurysm in the natural history of isolated perimembranous ventricular septal defect.
Ramaciotti C, Keren A, Silverman NH
Am J Cardiol 1986 Feb 1;57(4):268-72. doi: 10.1016/0002-9149(86)90903-3. PMID: 3946216

Clinical prediction guides

A case presentation of acquired membranous ventricular septum aneurysm as a rare delayed complication of ventricular septal defect repair surgery: 10-year follow-up.
Liu Z, Liang T, Jia S, Zhang W, Feng Y, Huang H
BMC Cardiovasc Disord 2023 Jul 12;23(1):346. doi: 10.1186/s12872-023-03361-1. PMID: 37438743Free PMC Article
Perventricular closure of perimembranous ventricular septal defects using the concentric occluder device.
Wang S, Zhuang Z, Zhang H, Zhen J, Lu Y, Liu J, Xu Z
Pediatr Cardiol 2014 Apr;35(4):580-6. Epub 2013 Nov 7 doi: 10.1007/s00246-013-0823-0. PMID: 24196912
Membranous ventricular septal aneurysm diagnosed by means of cardiac computed tomography.
Afaneh AB, Wymer DC, Kraft S, Winchester DE
Tex Heart Inst J 2012;39(3):450-1. PMID: 22719170Free PMC Article
Ventricular septal defect with secondary left ventricular-to-right atrial shunt is associated with a higher risk for infective endocarditis and a lower late chance of closure.
Wu MH, Wang JK, Lin MT, Wu ET, Lu FL, Chiu SN, Lue HC
Pediatrics 2006 Feb;117(2):e262-7. Epub 2006 Jan 17 doi: 10.1542/peds.2005-1255. PMID: 16418312
Echocardiographic recognition of ventricular septal aneurysm--a case report.
Sahn DJ, Kirkpatrick SE, Friedman WF
J Clin Ultrasound 1975 Dec;3(4):297-9. doi: 10.1002/jcu.1870030413. PMID: 829536

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