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Alcoholic cirrhosis

MedGen UID:
6125
•Concept ID:
C0023891
•
Disease or Syndrome
Synonyms: Alcoholic Cirrhosis; Alcoholic Hepatic Cirrhosis; Alcoholic Liver Cirrhosis; Hepatic Cirrhosis, Alcoholic; Liver Cirrhosis, Alcoholic
SNOMED CT: Alcoholic cirrhosis (420054005); Alcoholic liver cirrhosis (420054005); Alcoholic cirrhosis of liver (420054005)

Definition

A disorder of the liver characterized by the presence of fibrotic scar tissue instead of healthy liver tissue. This condition is attributed to excessive consumption of alcoholic beverages. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAlcoholic cirrhosis

Professional guidelines

PubMed

Diagnosis and Therapeutic Management of Liver Fibrosis by MicroRNA.
Tadokoro T, Morishita A, Masaki T
Int J Mol Sci 2021 Jul 29;22(15) doi: 10.3390/ijms22158139. PMID: 34360904Free PMC Article
Silymarin as Supportive Treatment in Liver Diseases: A Narrative Review.
Gillessen A, Schmidt HH
Adv Ther 2020 Apr;37(4):1279-1301. Epub 2020 Feb 17 doi: 10.1007/s12325-020-01251-y. PMID: 32065376Free PMC Article
ACG Clinical Guideline: Alcoholic Liver Disease.
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH
Am J Gastroenterol 2018 Feb;113(2):175-194. Epub 2018 Jan 16 doi: 10.1038/ajg.2017.469. PMID: 29336434Free PMC Article

Recent clinical studies

Etiology

Epidemiology of Alcohol Consumption and Societal Burden of Alcoholism and Alcoholic Liver Disease.
Axley PD, Richardson CT, Singal AK
Clin Liver Dis 2019 Feb;23(1):39-50. doi: 10.1016/j.cld.2018.09.011. PMID: 30454831
Liver transplantation and alcoholic liver disease: History, controversies, and considerations.
Marroni CA, Fleck AM Jr, Fernandes SA, Galant LH, Mucenic M, de Mattos Meine MH, Mariante-Neto G, Brandão ABM
World J Gastroenterol 2018 Jul 14;24(26):2785-2805. doi: 10.3748/wjg.v24.i26.2785. PMID: 30018475Free PMC Article
Liver transplantation for alcoholic hepatitis: A systematic review with meta-analysis.
Marot A, Dubois M, Trépo E, Moreno C, Deltenre P
PLoS One 2018;13(1):e0190823. Epub 2018 Jan 11 doi: 10.1371/journal.pone.0190823. PMID: 29324766Free PMC Article
Alcoholic cirrhosis and hepatocellular carcinoma.
Stickel F
Adv Exp Med Biol 2015;815:113-30. doi: 10.1007/978-3-319-09614-8_7. PMID: 25427904
Understanding and treating patients with alcoholic cirrhosis: an update.
Addolorato G, Russell M, Albano E, Haber PS, Wands JR, Leggio L
Alcohol Clin Exp Res 2009 Jul;33(7):1136-44. Epub 2009 Apr 21 doi: 10.1111/j.1530-0277.2009.00956.x. PMID: 19389182

Diagnosis

Advances in Nanoliposomes for the Diagnosis and Treatment of Liver Cancer.
Li Y, Zhang R, Xu Z, Wang Z
Int J Nanomedicine 2022;17:909-925. Epub 2022 Feb 26 doi: 10.2147/IJN.S349426. PMID: 35250267Free PMC Article
Hepatocellular carcinoma in the setting of alcohol-related liver disease.
Ganne-Carrié N, Nahon P
J Hepatol 2019 Feb;70(2):284-293. doi: 10.1016/j.jhep.2018.10.008. PMID: 30658729
Liver transplantation for alcoholic hepatitis: A systematic review with meta-analysis.
Marot A, Dubois M, Trépo E, Moreno C, Deltenre P
PLoS One 2018;13(1):e0190823. Epub 2018 Jan 11 doi: 10.1371/journal.pone.0190823. PMID: 29324766Free PMC Article
Jaundice.
Myers MB
Nurse Pract 1981 Mar-Apr;6(2):8-12, 27. doi: 10.1097/00006205-198106020-00003. PMID: 7207902
Alcoholic cirrhosis.
Burnett DA, Sorrell MF
Clin Gastroenterol 1981 May;10(2):443-55. PMID: 7018752

Therapy

Nutritional Support for Alcoholic Liver Disease.
Tadokoro T, Morishita A, Himoto T, Masaki T
Nutrients 2023 Mar 10;15(6) doi: 10.3390/nu15061360. PMID: 36986091Free PMC Article
The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt : A Randomized Controlled Trial.
Bureau C, Thabut D, Jezequel C, Archambeaud I, D'Alteroche L, Dharancy S, Borentain P, Oberti F, Plessier A, De Ledinghen V, Ganne-Carrié N, Carbonell N, Rousseau V, Sommet A, Péron JM, Vinel JP
Ann Intern Med 2021 May;174(5):633-640. Epub 2021 Feb 2 doi: 10.7326/M20-0202. PMID: 33524293
Alcohol and the liver.
Reuben A
Curr Opin Gastroenterol 2007 May;23(3):283-91. doi: 10.1097/MOG.0b013e3280f27582. PMID: 17414844
Colchicine for alcoholic and non-alcoholic liver fibrosis and cirrhosis.
Rambaldi A, Gluud C
Cochrane Database Syst Rev 2001;(3):CD002148. doi: 10.1002/14651858.CD002148. PMID: 11687017
Alcoholic liver disease.
Pimstone NR, French SW
Med Clin North Am 1984 Jan;68(1):39-56. doi: 10.1016/s0025-7125(16)31240-8. PMID: 6361417

Prognosis

Nutritional Support for Alcoholic Liver Disease.
Tadokoro T, Morishita A, Himoto T, Masaki T
Nutrients 2023 Mar 10;15(6) doi: 10.3390/nu15061360. PMID: 36986091Free PMC Article
Hepatocellular carcinoma in the setting of alcohol-related liver disease.
Ganne-Carrié N, Nahon P
J Hepatol 2019 Feb;70(2):284-293. doi: 10.1016/j.jhep.2018.10.008. PMID: 30658729
Management of patients with liver diseases on the waiting list for transplantation: a major impact to the success of liver transplantation.
Samuel D, Coilly A
BMC Med 2018 Aug 1;16(1):113. doi: 10.1186/s12916-018-1110-y. PMID: 30064414Free PMC Article
Liver transplantation and alcoholic liver disease: History, controversies, and considerations.
Marroni CA, Fleck AM Jr, Fernandes SA, Galant LH, Mucenic M, de Mattos Meine MH, Mariante-Neto G, Brandão ABM
World J Gastroenterol 2018 Jul 14;24(26):2785-2805. doi: 10.3748/wjg.v24.i26.2785. PMID: 30018475Free PMC Article
Alcoholic cirrhosis.
Burnett DA, Sorrell MF
Clin Gastroenterol 1981 May;10(2):443-55. PMID: 7018752

Clinical prediction guides

Association Between Alcoholic Cirrhosis and Hemorrhagic Stroke: A Nationwide Population-based Study.
Lin SY, Lin CL, Chen WS, Lin CC, Lin CH, Hsu WH, Hsu CY, Kao CH
Alcohol Alcohol 2019 May 1;54(3):302-309. doi: 10.1093/alcalc/agz025. PMID: 30957143
Liver Transplantation in France.
Durand F, Antoine C, Soubrane O
Liver Transpl 2019 May;25(5):763-770. Epub 2019 Apr 1 doi: 10.1002/lt.25419. PMID: 30697904
Management of patients with liver diseases on the waiting list for transplantation: a major impact to the success of liver transplantation.
Samuel D, Coilly A
BMC Med 2018 Aug 1;16(1):113. doi: 10.1186/s12916-018-1110-y. PMID: 30064414Free PMC Article
Epidemiology and Natural History of Alcoholic Liver Disease.
Masarone M, Rosato V, Dallio M, Abenavoli L, Federico A, Loguercio C, Persico M
Rev Recent Clin Trials 2016;11(3):167-74. doi: 10.2174/1574887111666160810101202. PMID: 27515957
Alcohol and the liver.
Reuben A
Curr Opin Gastroenterol 2006 May;22(3):263-71. doi: 10.1097/01.mog.0000218963.93806.d3. PMID: 16550041

Recent systematic reviews

Non-Alcoholic Cirrhosis and Heart Rate Variability: A Systematic Mini-Review.
Amaral JATD, Salatini R, Arab C, Abreu LC, Valenti VE, Monteiro CBM, Tannuri U, Tannuri ACA
Medicina (Kaunas) 2020 Mar 5;56(3) doi: 10.3390/medicina56030116. PMID: 32151106Free PMC Article
Silymarin as Supportive Treatment in Liver Diseases: A Narrative Review.
Gillessen A, Schmidt HH
Adv Ther 2020 Apr;37(4):1279-1301. Epub 2020 Feb 17 doi: 10.1007/s12325-020-01251-y. PMID: 32065376Free PMC Article
Liver transplantation for alcoholic hepatitis: A systematic review with meta-analysis.
Marot A, Dubois M, Trépo E, Moreno C, Deltenre P
PLoS One 2018;13(1):e0190823. Epub 2018 Jan 11 doi: 10.1371/journal.pone.0190823. PMID: 29324766Free PMC Article
Ultrasonography for diagnosis of alcoholic cirrhosis in people with alcoholic liver disease.
Pavlov CS, Casazza G, Semenistaia M, Nikolova D, Tsochatzis E, Liusina E, Ivashkin VT, Gluud C
Cochrane Database Syst Rev 2016 Mar 2;3(3):CD011602. doi: 10.1002/14651858.CD011602.pub2. PMID: 26934429Free PMC Article
Systematic review with meta-analysis: coffee consumption and the risk of cirrhosis.
Kennedy OJ, Roderick P, Buchanan R, Fallowfield JA, Hayes PC, Parkes J
Aliment Pharmacol Ther 2016 Mar;43(5):562-74. Epub 2016 Jan 25 doi: 10.1111/apt.13523. PMID: 26806124

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