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Dot-and-blot retinal hemorrhage

MedGen UID:
633876
•Concept ID:
C0474358
•
Pathologic Function
Synonyms: Dot-and-blot retinal haemorrhage; Retinal blot hemorrhage; Retinal dot blot hemorrhage; Retinal dot hemorrhage; Round retinal heme
SNOMED CT: Retinal dot hemorrhage (247133006); Retinal dot blot hemorrhage (247133006); Retinal blot hemorrhage (247133006)
 
HPO: HP:0025242

Definition

Accumulation of blood located in the retina's inner nuclear and outer plexiform layers, and having a dot-like or blot-like shape. THe shape results from intraretinal compression, restricting the hemorrhages within a specific location. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDot-and-blot retinal hemorrhage

Recent clinical studies

Etiology

Retinopathy of prematurity screening and retinal hemorrhages - Our experience among Indian babies.
Hemalatha BC, Kalpana BN, Shilpa YD, Ravi B, Bhavana G, Meghana S, Basumatary J
Indian J Ophthalmol 2021 Aug;69(8):2147-2150. doi: 10.4103/ijo.IJO_3616_20. PMID: 34304198Free PMC Article
Optic Nerve Head Hemorrhages Associated With Posterior Vitreous Detachment.
Polkinghorne PJ
Asia Pac J Ophthalmol (Phila) 2018 Mar-Apr;7(2):119-122. Epub 2017 Oct 24 doi: 10.22608/APO.2017340. PMID: 29063741
Decompression retinopathy after glaucoma surgery in children.
Fadel AM, Bessa AS, Bayoumi NH, Gonnah Rel S
J AAPOS 2015 Jun;19(3):286-9. Epub 2015 Apr 18 doi: 10.1016/j.jaapos.2015.02.003. PMID: 25900770
Branch retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complications. An update of the literature.
Jaulim A, Ahmed B, Khanam T, Chatziralli IP
Retina 2013 May;33(5):901-10. doi: 10.1097/IAE.0b013e3182870c15. PMID: 23609064
Retinal vascular abnormalities in patients with cerebral amyloid angiopathy.
Lee A, Rudkin A, Agzarian M, Patel S, Lake S, Chen C
Cerebrovasc Dis 2009;28(6):618-22. Epub 2009 Oct 22 doi: 10.1159/000251173. PMID: 19851067

Diagnosis

Bilateral Retinal Vasculitis as Initial Presentation of Systemic Lupus Erythematosus with Secondary Antiphospholipid Syndrome.
Aldhefeery N, Alhadhood N, Alkadi A
Am J Case Rep 2023 Nov 28;24:e942085. doi: 10.12659/AJCR.942085. PMID: 38013402Free PMC Article
Bilateral papilledema associated with retinal hemorrhagic appearance as earliest sign of spinal cord tumor.
Giannuzzi F, Carlà MM, Boselli F, Caputo CG, Fossataro C, Gambini G, Caporossi T, Vico U, Rizzo S
Eur J Ophthalmol 2023 Sep;33(5):NP75-NP78. Epub 2022 Oct 9 doi: 10.1177/11206721221132414. PMID: 36214152
Retinopathy of prematurity screening and retinal hemorrhages - Our experience among Indian babies.
Hemalatha BC, Kalpana BN, Shilpa YD, Ravi B, Bhavana G, Meghana S, Basumatary J
Indian J Ophthalmol 2021 Aug;69(8):2147-2150. doi: 10.4103/ijo.IJO_3616_20. PMID: 34304198Free PMC Article
LEUKEMIC OPTIC NERVE INFILTRATION IN A PATIENT WITH ACUTE LYMPHOBLASTIC LEUKEMIA.
Nagpal MP, Mehrotra NS, Mehta RC, Shukla CK
Retin Cases Brief Rep 2016 Spring;10(2):127-30. doi: 10.1097/ICB.0000000000000187. PMID: 26267525
Branch retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complications. An update of the literature.
Jaulim A, Ahmed B, Khanam T, Chatziralli IP
Retina 2013 May;33(5):901-10. doi: 10.1097/IAE.0b013e3182870c15. PMID: 23609064

Therapy

Bilateral Retinal Vasculitis as Initial Presentation of Systemic Lupus Erythematosus with Secondary Antiphospholipid Syndrome.
Aldhefeery N, Alhadhood N, Alkadi A
Am J Case Rep 2023 Nov 28;24:e942085. doi: 10.12659/AJCR.942085. PMID: 38013402Free PMC Article
Asymptomatic peripheral retinal hemorrhages as a manifestation of interferon beta 1a retinopathy.
Bakri SJ, Swanson JW
Semin Ophthalmol 2015 Jan;30(1):56-7. Epub 2013 Aug 16 doi: 10.3109/08820538.2013.814693. PMID: 23952180
Decompression retinopathy after Ahmed glaucoma valve implantation in a patient with congenital aniridia and pseudophakia.
Yalvac IS, Kocaoglan H, Eksioglu U, Demir N, Duman S
J Cataract Refract Surg 2004 Jul;30(7):1582-5. doi: 10.1016/j.jcrs.2003.11.046. PMID: 15210243

Prognosis

Bilateral Retinal Vasculitis as Initial Presentation of Systemic Lupus Erythematosus with Secondary Antiphospholipid Syndrome.
Aldhefeery N, Alhadhood N, Alkadi A
Am J Case Rep 2023 Nov 28;24:e942085. doi: 10.12659/AJCR.942085. PMID: 38013402Free PMC Article
Retinal changes in COVID-19 hospitalized cases.
Lani-Louzada R, Ramos CDVF, Cordeiro RM, Sadun AA
PLoS One 2020;15(12):e0243346. Epub 2020 Dec 3 doi: 10.1371/journal.pone.0243346. PMID: 33270751Free PMC Article
Branch retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complications. An update of the literature.
Jaulim A, Ahmed B, Khanam T, Chatziralli IP
Retina 2013 May;33(5):901-10. doi: 10.1097/IAE.0b013e3182870c15. PMID: 23609064
Retinal vascular abnormalities in patients with cerebral amyloid angiopathy.
Lee A, Rudkin A, Agzarian M, Patel S, Lake S, Chen C
Cerebrovasc Dis 2009;28(6):618-22. Epub 2009 Oct 22 doi: 10.1159/000251173. PMID: 19851067
Decompression retinopathy after Ahmed glaucoma valve implantation in a patient with congenital aniridia and pseudophakia.
Yalvac IS, Kocaoglan H, Eksioglu U, Demir N, Duman S
J Cataract Refract Surg 2004 Jul;30(7):1582-5. doi: 10.1016/j.jcrs.2003.11.046. PMID: 15210243

Clinical prediction guides

Retinal changes in COVID-19 hospitalized cases.
Lani-Louzada R, Ramos CDVF, Cordeiro RM, Sadun AA
PLoS One 2020;15(12):e0243346. Epub 2020 Dec 3 doi: 10.1371/journal.pone.0243346. PMID: 33270751Free PMC Article
Branch retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complications. An update of the literature.
Jaulim A, Ahmed B, Khanam T, Chatziralli IP
Retina 2013 May;33(5):901-10. doi: 10.1097/IAE.0b013e3182870c15. PMID: 23609064
Decompression retinopathy after Ahmed glaucoma valve implantation in a patient with congenital aniridia and pseudophakia.
Yalvac IS, Kocaoglan H, Eksioglu U, Demir N, Duman S
J Cataract Refract Surg 2004 Jul;30(7):1582-5. doi: 10.1016/j.jcrs.2003.11.046. PMID: 15210243

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