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Pseudolymphoma

MedGen UID:
67450
•Concept ID:
C0221269
•
Neoplastic Process
Synonyms: Hyperplasia, Reactive Lymphoid; Hyperplasias, Reactive Lymphoid; Lymphocytoma; Lymphocytomas; Lymphoid Hyperplasia, Reactive; Lymphoid Hyperplasias, Reactive; Pseudolymphomas; Reactive Lymphoid Hyperplasia; Reactive Lymphoid Hyperplasias
SNOMED CT: Benign lymphoid hyperplasia (19750001); Pseudolymphoma (19750001); Reactive lymphoid hyperplasia (43961000)
 
Monarch Initiative: MONDO:0043959

Definition

A neoplastic process that resembles a malignant lymphoma, but has a benign course. [from NCI]

Professional guidelines

PubMed

Treatment of Cutaneous Pseudolymphoma: A Systematic Review.
Miguel D, Peckruhn M, Elsner P
Acta Derm Venereol 2018 Mar 13;98(3):310-317. doi: 10.2340/00015555-2841. PMID: 29136262
Drug-associated lymphoma and pseudolymphoma: recognition and management.
Albrecht J, Fine LA, Piette W
Dermatol Clin 2007 Apr;25(2):233-44, vii. doi: 10.1016/j.det.2007.01.008. PMID: 17430760
CD30+ lymphoproliferative disorders: histopathology, differential diagnosis, new variants, and simulators.
Kempf W
J Cutan Pathol 2006 Feb;33 Suppl 1:58-70. doi: 10.1111/j.0303-6987.2006.00548.x. PMID: 16412214

Recent clinical studies

Etiology

Cutaneous pseudolymphoma-A review on the spectrum and a proposal for a new classification.
Mitteldorf C, Kempf W
J Cutan Pathol 2020 Jan;47(1):76-97. Epub 2019 Jul 31 doi: 10.1111/cup.13532. PMID: 31237707
Overview of fever of unknown origin in adult and paediatric patients.
Attard L, Tadolini M, De Rose DU, Cattalini M
Clin Exp Rheumatol 2018 Jan-Feb;36 Suppl 110(1):10-24. Epub 2018 May 3 PMID: 29742054
Cutaneous Pseudolymphoma.
Mitteldorf C, Kempf W
Surg Pathol Clin 2017 Jun;10(2):455-476. Epub 2017 Mar 22 doi: 10.1016/j.path.2017.01.002. PMID: 28477891
Tattoos: dermatological complications.
Kazandjieva J, Tsankov N
Clin Dermatol 2007 Jul-Aug;25(4):375-82. doi: 10.1016/j.clindermatol.2007.05.012. PMID: 17697920
Cutaneous pseudolymphomas.
Ploysangam T, Breneman DL, Mutasim DF
J Am Acad Dermatol 1998 Jun;38(6 Pt 1):877-95; quiz 896-7. doi: 10.1016/s0190-9622(98)70154-9. PMID: 9631994

Diagnosis

Cutaneous pseudolymphoma-A review on the spectrum and a proposal for a new classification.
Mitteldorf C, Kempf W
J Cutan Pathol 2020 Jan;47(1):76-97. Epub 2019 Jul 31 doi: 10.1111/cup.13532. PMID: 31237707
Cutaneous Pseudolymphoma.
Mitteldorf C, Kempf W
Surg Pathol Clin 2017 Jun;10(2):455-476. Epub 2017 Mar 22 doi: 10.1016/j.path.2017.01.002. PMID: 28477891
Lymphocytic Interstitial Pneumonia.
Panchabhai TS, Farver C, Highland KB
Clin Chest Med 2016 Sep;37(3):463-74. Epub 2016 Jun 25 doi: 10.1016/j.ccm.2016.04.009. PMID: 27514593
Cutaneous Pseudolymphomas.
Romero-Pérez D, Blanes Martínez M, Encabo-Durán B
Actas Dermosifiliogr 2016 Oct;107(8):640-51. Epub 2016 Jun 8 doi: 10.1016/j.ad.2016.05.003. PMID: 27289134
Gastrointestinal lymphoma.
Skinner JM
Pathology 1985 Apr;17(2):193-203. doi: 10.3109/00313028509063755. PMID: 3900895

Therapy

Cutaneous pseudolymphoma-A review on the spectrum and a proposal for a new classification.
Mitteldorf C, Kempf W
J Cutan Pathol 2020 Jan;47(1):76-97. Epub 2019 Jul 31 doi: 10.1111/cup.13532. PMID: 31237707
HIV-Associated Psoriasis.
Queirós N, Torres T
Actas Dermosifiliogr (Engl Ed) 2018 May;109(4):303-311. Epub 2018 Feb 1 doi: 10.1016/j.ad.2017.09.014. PMID: 29361272
Lymphocytic Interstitial Pneumonia.
Panchabhai TS, Farver C, Highland KB
Clin Chest Med 2016 Sep;37(3):463-74. Epub 2016 Jun 25 doi: 10.1016/j.ccm.2016.04.009. PMID: 27514593
Cutaneous Pseudolymphomas.
Romero-Pérez D, Blanes Martínez M, Encabo-Durán B
Actas Dermosifiliogr 2016 Oct;107(8):640-51. Epub 2016 Jun 8 doi: 10.1016/j.ad.2016.05.003. PMID: 27289134
Tattoos: dermatological complications.
Kazandjieva J, Tsankov N
Clin Dermatol 2007 Jul-Aug;25(4):375-82. doi: 10.1016/j.clindermatol.2007.05.012. PMID: 17697920

Prognosis

Pseudolymphomatous Atypical Fibroxanthoma.
Garcia Castro R, Viñolas-Cuadros A, Moyano-Bueno D, Conde-Ferreiros A, Cardeñoso E, Santos-Briz A
Am J Dermatopathol 2020 Dec;42(12):972-976. doi: 10.1097/DAD.0000000000001761. PMID: 32769551
Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma.
Zhou X, Chen N, Xu H, Zhou X, Wang J, Fang X, Zhang Y, Li Y, Yang J, Wang X
J Hematol Oncol 2020 Jun 16;13(1):77. doi: 10.1186/s13045-020-00906-1. PMID: 32546241Free PMC Article
Dermoscopy of Lymphomas and Pseudolymphomas.
Bombonato C, Pampena R, Lallas A, Giovanni P, Longo C
Dermatol Clin 2018 Oct;36(4):377-388. Epub 2018 Aug 14 doi: 10.1016/j.det.2018.05.005. PMID: 30201147
Cutaneous Pseudolymphomas.
Romero-Pérez D, Blanes Martínez M, Encabo-Durán B
Actas Dermosifiliogr 2016 Oct;107(8):640-51. Epub 2016 Jun 8 doi: 10.1016/j.ad.2016.05.003. PMID: 27289134
Cutaneous lymphoid hyperplasias.
Gilliam AC, Wood GS
Semin Cutan Med Surg 2000 Jun;19(2):133-41. doi: 10.1016/s1085-5629(00)80011-5. PMID: 10892716

Clinical prediction guides

Cutaneous reactive B-cell lymphoid proliferations.
Khalil S, Donthi D, Gru AA
J Cutan Pathol 2022 Oct;49(10):898-916. Epub 2022 Aug 4 doi: 10.1111/cup.14264. PMID: 35656820
Pseudolymphomatous Atypical Fibroxanthoma.
Garcia Castro R, Viñolas-Cuadros A, Moyano-Bueno D, Conde-Ferreiros A, Cardeñoso E, Santos-Briz A
Am J Dermatopathol 2020 Dec;42(12):972-976. doi: 10.1097/DAD.0000000000001761. PMID: 32769551
Treatment of Cutaneous Pseudolymphoma: A Systematic Review.
Miguel D, Peckruhn M, Elsner P
Acta Derm Venereol 2018 Mar 13;98(3):310-317. doi: 10.2340/00015555-2841. PMID: 29136262
Cutaneous targets in drug-induced reactions.
Filotico R, Mastrandrea V
G Ital Dermatol Venereol 2014 Apr;149(2):227-35. PMID: 24819644
Cutaneous lymphoid hyperplasias.
Gilliam AC, Wood GS
Semin Cutan Med Surg 2000 Jun;19(2):133-41. doi: 10.1016/s1085-5629(00)80011-5. PMID: 10892716

Recent systematic reviews

Drug-induced cutaneous pseudolymphoma: A systematic review of the literature.
Etesami I, Kalantari Y, Tavakolpour S, Mahmoudi H, Daneshpazhooh M
Australas J Dermatol 2023 Feb;64(1):41-49. Epub 2022 Nov 4 doi: 10.1111/ajd.13951. PMID: 36331821
Clinical features, natural history and outcomes of pseudolymphoma of liver: A case-series and systematic review.
Jiang W, Wu D, Li Q, Liu CH, Zeng Q, Chen E, Lu C, Tang H
Asian J Surg 2023 Feb;46(2):841-849. Epub 2022 Sep 16 doi: 10.1016/j.asjsur.2022.08.113. PMID: 36123208
Treatment of Cutaneous Pseudolymphoma: A Systematic Review.
Miguel D, Peckruhn M, Elsner P
Acta Derm Venereol 2018 Mar 13;98(3):310-317. doi: 10.2340/00015555-2841. PMID: 29136262
Atypical presentations of cutaneous leishmaniasis: A systematic review.
Meireles CB, Maia LC, Soares GC, Teodoro IPP, Gadelha MDSV, da Silva CGL, de Lima MAP
Acta Trop 2017 Aug;172:240-254. Epub 2017 May 17 doi: 10.1016/j.actatropica.2017.05.022. PMID: 28526427

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