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Deficiency of vitamin D3

MedGen UID:
695925
•Concept ID:
C1272352
•
Disease or Syndrome
Synonyms: Deficiency of vitamin D>3<; Vitamin D3 Deficiency
SNOMED CT: Deficiency of vitamin D3 (386072000); Deficiency of vitamin D>3< (386072000)

Definition

Abnormally low concentration of vitamin D3 (cholecalciferol) in the blood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDeficiency of vitamin D3

Professional guidelines

PubMed

Prevalence and Treatment of Vitamin D Deficiency in Young Male Russian Soccer Players in Winter.
Bezuglov E, Tikhonova A, Zueva A, Khaitin V, Waśkiewicz Z, Gerasimuk D, Żebrowska A, Rosemann T, Nikolaidis P, Knechtle B
Nutrients 2019 Oct 8;11(10) doi: 10.3390/nu11102405. PMID: 31597404Free PMC Article

Recent clinical studies

Etiology

Level of vitamin 25 (OH) D and B group vitamins and functional efficiency among the chronically ill elderly in domiciliary care - a pilot study.
Kocka KH, Ślusarska BJ, Nowicki GJ, Bartoszek AB, Rudnicka-Drożak EA, Panasiuk L, Kocki T
Ann Agric Environ Med 2019 Sep 19;26(3):489-495. Epub 2019 Mar 18 doi: 10.26444/aaem/105801. PMID: 31559809
Lesional and circulating levels of interleukin-17 and 25-hydroxycholecalciferol in active acne vulgaris: Correlation to disease severity.
Abd-Elmaged WM, Nada EA, Hassan MH, Elsadek BEM, Abdelrahim EA, Ahmed NS, Toghan R, Ahmed HTI
J Cosmet Dermatol 2019 Apr;18(2):671-676. Epub 2018 Aug 2 doi: 10.1111/jocd.12715. PMID: 30070012
Are Shiftwork and Indoor Work Related to D3 Vitamin Deficiency? A Systematic Review of Current Evidences.
Coppeta L, Papa F, Magrini A
J Environ Public Health 2018;2018:8468742. Epub 2018 Sep 10 doi: 10.1155/2018/8468742. PMID: 30275842Free PMC Article

Diagnosis

A rare case of a giant cell tumour caused by vitamin D deficiency.
Neychev D, Pilichev B, Serteva D, Kanazirska P
Folia Med (Plovdiv) 2022 Aug 31;64(4):676-681. doi: 10.3897/folmed.64.e63623. PMID: 36045471
Lesional and circulating levels of interleukin-17 and 25-hydroxycholecalciferol in active acne vulgaris: Correlation to disease severity.
Abd-Elmaged WM, Nada EA, Hassan MH, Elsadek BEM, Abdelrahim EA, Ahmed NS, Toghan R, Ahmed HTI
J Cosmet Dermatol 2019 Apr;18(2):671-676. Epub 2018 Aug 2 doi: 10.1111/jocd.12715. PMID: 30070012

Therapy

A rare case of a giant cell tumour caused by vitamin D deficiency.
Neychev D, Pilichev B, Serteva D, Kanazirska P
Folia Med (Plovdiv) 2022 Aug 31;64(4):676-681. doi: 10.3897/folmed.64.e63623. PMID: 36045471
Vitamin D3 alleviates pulmonary fibrosis by regulating the MAPK pathway via targeting PSAT1 expression in vivo and in vitro.
Zhu W, Ding Q, Wang L, Xu G, Diao Y, Qu S, Chen S, Shi Y
Int Immunopharmacol 2021 Dec;101(Pt B):108212. Epub 2021 Oct 14 doi: 10.1016/j.intimp.2021.108212. PMID: 34656907
Photoprotection: facts and controversies.
Skotarczak K, Osmola-Mańkowska A, Lodyga M, Polańska A, Mazur M, Adamski Z
Eur Rev Med Pharmacol Sci 2015 Jan;19(1):98-112. PMID: 25635982
Severe deficiency of 25-hydroxyvitamin D₃ (25-OH-D₃) is associated with high disease activity of rheumatoid arthritis.
Haga HJ, Schmedes A, Naderi Y, Moreno AM, Peen E
Clin Rheumatol 2013 May;32(5):629-33. Epub 2013 Jan 15 doi: 10.1007/s10067-012-2154-6. PMID: 23318705

Prognosis

Are Shiftwork and Indoor Work Related to D3 Vitamin Deficiency? A Systematic Review of Current Evidences.
Coppeta L, Papa F, Magrini A
J Environ Public Health 2018;2018:8468742. Epub 2018 Sep 10 doi: 10.1155/2018/8468742. PMID: 30275842Free PMC Article

Clinical prediction guides

Level of vitamin 25 (OH) D and B group vitamins and functional efficiency among the chronically ill elderly in domiciliary care - a pilot study.
Kocka KH, Ślusarska BJ, Nowicki GJ, Bartoszek AB, Rudnicka-Drożak EA, Panasiuk L, Kocki T
Ann Agric Environ Med 2019 Sep 19;26(3):489-495. Epub 2019 Mar 18 doi: 10.26444/aaem/105801. PMID: 31559809
Severe deficiency of 25-hydroxyvitamin D₃ (25-OH-D₃) is associated with high disease activity of rheumatoid arthritis.
Haga HJ, Schmedes A, Naderi Y, Moreno AM, Peen E
Clin Rheumatol 2013 May;32(5):629-33. Epub 2013 Jan 15 doi: 10.1007/s10067-012-2154-6. PMID: 23318705

Recent systematic reviews

Are Shiftwork and Indoor Work Related to D3 Vitamin Deficiency? A Systematic Review of Current Evidences.
Coppeta L, Papa F, Magrini A
J Environ Public Health 2018;2018:8468742. Epub 2018 Sep 10 doi: 10.1155/2018/8468742. PMID: 30275842Free PMC Article

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