U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Allergy to bee venom

MedGen UID:
742044
•Concept ID:
C1828283
•
Pathologic Function
Synonyms: Bee Sting Allergy; Bee Venom Allergy
SNOMED CT: Allergy to bee venom (424213003)

Definition

An allergic reaction triggered by being exposed to bee venom following a bee sting. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAllergy to bee venom

Professional guidelines

PubMed

A systematic review of the clinical effectiveness and cost-effectiveness of Pharmalgen® for the treatment of bee and wasp venom allergy.
Hockenhull J, Elremeli M, Cherry MG, Mahon J, Lai M, Darroch J, Oyee J, Boland A, Dickson R, Dundar Y, Boyle R
Health Technol Assess 2012;16(12):III-IV, 1-110. doi: 10.3310/hta16120. PMID: 22409877Free PMC Article

Recent clinical studies

Etiology

Venom allergen immunotherapy.
Golden DBK
Allergy Asthma Proc 2022 Jul 1;43(4):339-343. doi: 10.2500/aap.2022.43.210109. PMID: 35818146
Stinging insect allergy and venom immunotherapy.
Ochfeld EN, Greenberger PA
Allergy Asthma Proc 2019 Nov 1;40(6):372-375. doi: 10.2500/aap.2019.40.4250. PMID: 31690373
Immunotherapy and biologicals for the treatment of allergy to Hymenoptera stings.
Ridolo E, Pellicelli I, Kihlgren P, Nizi MC, Pucciarini F, Senna G, Incorvaia C
Expert Opin Biol Ther 2019 Sep;19(9):919-925. Epub 2019 Jun 21 doi: 10.1080/14712598.2019.1632286. PMID: 31190572
EAACI guidelines on allergen immunotherapy: Hymenoptera venom allergy.
Sturm GJ, Varga EM, Roberts G, Mosbech H, Bilò MB, Akdis CA, Antolín-Amérigo D, Cichocka-Jarosz E, Gawlik R, Jakob T, Kosnik M, Lange J, Mingomataj E, Mitsias DI, Ollert M, Oude Elberink JNG, Pfaar O, Pitsios C, Pravettoni V, Ruëff F, Sin BA, Agache I, Angier E, Arasi S, Calderón MA, Fernandez-Rivas M, Halken S, Jutel M, Lau S, Pajno GB, van Ree R, Ryan D, Spranger O, van Wijk RG, Dhami S, Zaman H, Sheikh A, Muraro A
Allergy 2018 Apr;73(4):744-764. Epub 2017 Dec 5 doi: 10.1111/all.13262. PMID: 28748641
Hymenoptera venom allergy.
Przybilla B, Ruëff F
J Dtsch Dermatol Ges 2010 Feb;8(2):114-27; quiz 128-30. Epub 2009 Sep 14 doi: 10.1111/j.1610-0387.2009.07125.x. PMID: 19751222

Diagnosis

A Review of Honeybee Venom Allergens and Allergenicity.
Burzyńska M, Piasecka-Kwiatkowska D
Int J Mol Sci 2021 Aug 4;22(16) doi: 10.3390/ijms22168371. PMID: 34445077Free PMC Article
Honeybee and wasp venom allergy: Sensitization and immunotherapy.
Adib-Tezer H, Bayerl C
J Dtsch Dermatol Ges 2018 Oct;16(10):1228-1247. doi: 10.1111/ddg.13670. PMID: 30300499
Immunology of Bee Venom.
Elieh Ali Komi D, Shafaghat F, Zwiener RD
Clin Rev Allergy Immunol 2018 Jun;54(3):386-396. doi: 10.1007/s12016-017-8597-4. PMID: 28105558
Allergy to honeybee … not only stings.
Cifuentes L
Curr Opin Allergy Clin Immunol 2015 Aug;15(4):364-8. doi: 10.1097/ACI.0000000000000191. PMID: 26110688
Hymenoptera venom allergy.
Przybilla B, Ruëff F
J Dtsch Dermatol Ges 2010 Feb;8(2):114-27; quiz 128-30. Epub 2009 Sep 14 doi: 10.1111/j.1610-0387.2009.07125.x. PMID: 19751222

Therapy

Venom allergen immunotherapy.
Golden DBK
Allergy Asthma Proc 2022 Jul 1;43(4):339-343. doi: 10.2500/aap.2022.43.210109. PMID: 35818146
A Review of Honeybee Venom Allergens and Allergenicity.
Burzyńska M, Piasecka-Kwiatkowska D
Int J Mol Sci 2021 Aug 4;22(16) doi: 10.3390/ijms22168371. PMID: 34445077Free PMC Article
Stinging insect allergy and venom immunotherapy.
Ochfeld EN, Greenberger PA
Allergy Asthma Proc 2019 Nov 1;40(6):372-375. doi: 10.2500/aap.2019.40.4250. PMID: 31690373
Immunotherapy and biologicals for the treatment of allergy to Hymenoptera stings.
Ridolo E, Pellicelli I, Kihlgren P, Nizi MC, Pucciarini F, Senna G, Incorvaia C
Expert Opin Biol Ther 2019 Sep;19(9):919-925. Epub 2019 Jun 21 doi: 10.1080/14712598.2019.1632286. PMID: 31190572
EAACI guidelines on allergen immunotherapy: Hymenoptera venom allergy.
Sturm GJ, Varga EM, Roberts G, Mosbech H, Bilò MB, Akdis CA, Antolín-Amérigo D, Cichocka-Jarosz E, Gawlik R, Jakob T, Kosnik M, Lange J, Mingomataj E, Mitsias DI, Ollert M, Oude Elberink JNG, Pfaar O, Pitsios C, Pravettoni V, Ruëff F, Sin BA, Agache I, Angier E, Arasi S, Calderón MA, Fernandez-Rivas M, Halken S, Jutel M, Lau S, Pajno GB, van Ree R, Ryan D, Spranger O, van Wijk RG, Dhami S, Zaman H, Sheikh A, Muraro A
Allergy 2018 Apr;73(4):744-764. Epub 2017 Dec 5 doi: 10.1111/all.13262. PMID: 28748641

Prognosis

Venom allergen immunotherapy.
Golden DBK
Allergy Asthma Proc 2022 Jul 1;43(4):339-343. doi: 10.2500/aap.2022.43.210109. PMID: 35818146
Stinging insect allergy and venom immunotherapy.
Ochfeld EN, Greenberger PA
Allergy Asthma Proc 2019 Nov 1;40(6):372-375. doi: 10.2500/aap.2019.40.4250. PMID: 31690373
Immunotherapy and biologicals for the treatment of allergy to Hymenoptera stings.
Ridolo E, Pellicelli I, Kihlgren P, Nizi MC, Pucciarini F, Senna G, Incorvaia C
Expert Opin Biol Ther 2019 Sep;19(9):919-925. Epub 2019 Jun 21 doi: 10.1080/14712598.2019.1632286. PMID: 31190572
Molecular diagnosis and immunotherapy.
Sastre J, Sastre-Ibañez M
Curr Opin Allergy Clin Immunol 2016 Dec;16(6):565-570. doi: 10.1097/ACI.0000000000000318. PMID: 27685663
Hymenoptera venom allergy.
Przybilla B, Ruëff F
J Dtsch Dermatol Ges 2010 Feb;8(2):114-27; quiz 128-30. Epub 2009 Sep 14 doi: 10.1111/j.1610-0387.2009.07125.x. PMID: 19751222

Clinical prediction guides

Venom Anaphylaxis: Decision Points for a More Aggressive Workup.
Bonadonna P, Korosec P, Nalin F, Golden DBK
J Allergy Clin Immunol Pract 2023 Jul;11(7):2024-2031. Epub 2023 Apr 28 doi: 10.1016/j.jaip.2023.04.016. PMID: 37119981
Venom allergen immunotherapy.
Golden DBK
Allergy Asthma Proc 2022 Jul 1;43(4):339-343. doi: 10.2500/aap.2022.43.210109. PMID: 35818146
Hymenoptera Venom Allergy: How Does Venom Immunotherapy Prevent Anaphylaxis From Bee and Wasp Stings?
Sahiner UM, Durham SR
Front Immunol 2019;10:1959. Epub 2019 Aug 21 doi: 10.3389/fimmu.2019.01959. PMID: 31497015Free PMC Article
Molecular diagnosis and immunotherapy.
Sastre J, Sastre-Ibañez M
Curr Opin Allergy Clin Immunol 2016 Dec;16(6):565-570. doi: 10.1097/ACI.0000000000000318. PMID: 27685663
Hymenoptera venom allergy.
Przybilla B, Ruëff F
J Dtsch Dermatol Ges 2010 Feb;8(2):114-27; quiz 128-30. Epub 2009 Sep 14 doi: 10.1111/j.1610-0387.2009.07125.x. PMID: 19751222

Recent systematic reviews

Incidence Rate of Bee Venom Acupuncture Related Anaphylaxis: A Systematic Review.
Ko SH, Oh HM, Kwon DY, Yang JE, Kim BJ, Ha HJ, Lim EJ, Oh MS, Son CG, Lee EJ
Toxins (Basel) 2022 Mar 26;14(4) doi: 10.3390/toxins14040238. PMID: 35448847Free PMC Article
Risk associated with bee venom therapy: a systematic review and meta-analysis.
Park JH, Yim BK, Lee JH, Lee S, Kim TH
PLoS One 2015;10(5):e0126971. Epub 2015 May 21 doi: 10.1371/journal.pone.0126971. PMID: 25996493Free PMC Article
A systematic review of the clinical effectiveness and cost-effectiveness of Pharmalgen® for the treatment of bee and wasp venom allergy.
Hockenhull J, Elremeli M, Cherry MG, Mahon J, Lai M, Darroch J, Oyee J, Boland A, Dickson R, Dundar Y, Boyle R
Health Technol Assess 2012;16(12):III-IV, 1-110. doi: 10.3310/hta16120. PMID: 22409877Free PMC Article
Safety of hymenoptera venom immunotherapy: a systematic review.
Incorvaia C, Frati F, Dell'Albani I, Robino A, Cattaneo E, Mauro M, David M, Qualizza R, Pastorello E
Expert Opin Pharmacother 2011 Nov;12(16):2527-32. Epub 2011 Sep 2 doi: 10.1517/14656566.2011.616494. PMID: 21883032
Specific immunotherapy using Hymenoptera venom: systematic review.
Watanabe AS, Fonseca LA, Galvão CE, Kalil J, Castro FF
Sao Paulo Med J 2010 Jan;128(1):30-7. doi: 10.1590/s1516-31802010000100007. PMID: 20512278Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...