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Malaria

MedGen UID:
7443
Concept ID:
C0024530
Disease or Syndrome
Synonyms: Fever, Marsh; Fever, Remittent; Infection, Plasmodium; Infections, Plasmodium; Marsh Fever; Paludism; Plasmodium Infection; Plasmodium Infections; Remittent Fever
SNOMED CT: Malaria (61462000); Paludism (61462000); Plasmodiosis (61462000); Disease due to Plasmodiidae (105649009); Disease caused by Plasmodiidae (105649009); Malarial fever (248437004)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0005136
Orphanet: ORPHA673

Definition

A life-threatening parasitic disease caused by <i>Plasmodium</i> (<i>P. </i>) parasites that are transmitted by <i>Anophles</i> mosquito bites to humans and is typically clinically characterized by attacks of fever, headache, chills and vomiting. [from ORDO]

Professional guidelines

PubMed

Daily JP, Minuti A, Khan N
JAMA 2022 Aug 2;328(5):460-471. doi: 10.1001/jama.2022.12366. PMID: 35916842
Barber BE, Grigg MJ, Cooper DJ, van Schalkwyk DA, William T, Rajahram GS, Anstey NM
Adv Parasitol 2021;113:45-76. Epub 2021 Sep 1 doi: 10.1016/bs.apar.2021.08.004. PMID: 34620385Free PMC Article
Plewes K, Leopold SJ, Kingston HWF, Dondorp AM
Infect Dis Clin North Am 2019 Mar;33(1):39-60. doi: 10.1016/j.idc.2018.10.002. PMID: 30712767

Recent clinical studies

Etiology

Mohan K, Kumar M, Omar BJ
Curr Pediatr Rev 2023;19(3):242-252. doi: 10.2174/1573396318666220401110835. PMID: 35366778
Shahbodaghi SD, Rathjen NA
Am Fam Physician 2022 Sep;106(3):270-278. PMID: 36126008
Greenwood B, Zongo I, Dicko A, Chandramohan D, Snow RW, Ockenhouse C
Malar J 2022 Mar 9;21(1):77. doi: 10.1186/s12936-022-04098-6. PMID: 35264158Free PMC Article
Basu S, Sahi PK
Indian J Pediatr 2017 Jul;84(7):521-528. Epub 2017 Mar 30 doi: 10.1007/s12098-017-2332-2. PMID: 28357581
Suh KN, Kain KC, Keystone JS
CMAJ 2004 May 25;170(11):1693-702. doi: 10.1503/cmaj.1030418. PMID: 15159369Free PMC Article

Diagnosis

Song X, Wei W, Cheng W, Zhu H, Wang W, Dong H, Li J
Front Cell Infect Microbiol 2022;12:939532. Epub 2022 Jul 25 doi: 10.3389/fcimb.2022.939532. PMID: 35959375Free PMC Article
Walter K, John CC
JAMA 2022 Feb 8;327(6):597. doi: 10.1001/jama.2021.21468. PMID: 35133414
Varo R, Balanza N, Mayor A, Bassat Q
Expert Rev Anti Infect Ther 2021 Jan;19(1):79-92. Epub 2020 Aug 30 doi: 10.1080/14787210.2020.1807940. PMID: 32772759
Barros Pinto MP, Marques G
Infection 2020 Feb;48(1):143-146. Epub 2019 Nov 4 doi: 10.1007/s15010-019-01371-w. PMID: 31686322
Cohee LM, Laufer MK
Pediatr Clin North Am 2017 Aug;64(4):851-866. doi: 10.1016/j.pcl.2017.03.004. PMID: 28734514Free PMC Article

Therapy

Meo SA, Klonoff DC, Akram J
Eur Rev Med Pharmacol Sci 2020 Apr;24(8):4539-4547. doi: 10.26355/eurrev_202004_21038. PMID: 32373993
Haston JC, Hwang J, Tan KR
MMWR Morb Mortal Wkly Rep 2019 Nov 22;68(46):1062-1068. doi: 10.15585/mmwr.mm6846a4. PMID: 31751320Free PMC Article
Beeson JG, Kurtovic L, Dobaño C, Opi DH, Chan JA, Feng G, Good MF, Reiling L, Boyle MJ
Sci Transl Med 2019 Jan 9;11(474) doi: 10.1126/scitranslmed.aau1458. PMID: 30626712
Laurens MB
Annu Rev Microbiol 2018 Sep 8;72:273-292. doi: 10.1146/annurev-micro-090817-062427. PMID: 30200856
Dramowski A, Frigati L, Rabie H, Cotton M
Infect Disord Drug Targets 2013 Aug;13(4):303-11. doi: 10.2174/1871526513666131129154446. PMID: 24304356

Prognosis

Cohen JM, Okumu F, Moonen B
Sci Transl Med 2022 Jun 29;14(651):eabn3256. doi: 10.1126/scitranslmed.abn3256. PMID: 35767649
Premaratne R, Wickremasinghe R, Ranaweera D, Gunasekera WMKTAW, Hevawitharana M, Pieris L, Fernando D, Mendis K
Malar J 2019 Jul 29;18(1):256. doi: 10.1186/s12936-019-2886-8. PMID: 31358007Free PMC Article
Shi T, McAllister DA, O'Brien KL, Simoes EAF, Madhi SA, Gessner BD, Polack FP, Balsells E, Acacio S, Aguayo C, Alassani I, Ali A, Antonio M, Awasthi S, Awori JO, Azziz-Baumgartner E, Baggett HC, Baillie VL, Balmaseda A, Barahona A, Basnet S, Bassat Q, Basualdo W, Bigogo G, Bont L, Breiman RF, Brooks WA, Broor S, Bruce N, Bruden D, Buchy P, Campbell S, Carosone-Link P, Chadha M, Chipeta J, Chou M, Clara W, Cohen C, de Cuellar E, Dang DA, Dash-Yandag B, Deloria-Knoll M, Dherani M, Eap T, Ebruke BE, Echavarria M, de Freitas Lázaro Emediato CC, Fasce RA, Feikin DR, Feng L, Gentile A, Gordon A, Goswami D, Goyet S, Groome M, Halasa N, Hirve S, Homaira N, Howie SRC, Jara J, Jroundi I, Kartasasmita CB, Khuri-Bulos N, Kotloff KL, Krishnan A, Libster R, Lopez O, Lucero MG, Lucion F, Lupisan SP, Marcone DN, McCracken JP, Mejia M, Moisi JC, Montgomery JM, Moore DP, Moraleda C, Moyes J, Munywoki P, Mutyara K, Nicol MP, Nokes DJ, Nymadawa P, da Costa Oliveira MT, Oshitani H, Pandey N, Paranhos-Baccalà G, Phillips LN, Picot VS, Rahman M, Rakoto-Andrianarivelo M, Rasmussen ZA, Rath BA, Robinson A, Romero C, Russomando G, Salimi V, Sawatwong P, Scheltema N, Schweiger B, Scott JAG, Seidenberg P, Shen K, Singleton R, Sotomayor V, Strand TA, Sutanto A, Sylla M, Tapia MD, Thamthitiwat S, Thomas ED, Tokarz R, Turner C, Venter M, Waicharoen S, Wang J, Watthanaworawit W, Yoshida LM, Yu H, Zar HJ, Campbell H, Nair H; RSV Global Epidemiology Network
Lancet 2017 Sep 2;390(10098):946-958. Epub 2017 Jul 7 doi: 10.1016/S0140-6736(17)30938-8. PMID: 28689664Free PMC Article
RTS,S Clinical Trials Partnership
Lancet 2015 Jul 4;386(9988):31-45. Epub 2015 Apr 23 doi: 10.1016/S0140-6736(15)60721-8. PMID: 25913272Free PMC Article
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Barker-Collo S, Bartels DH, Bell ML, Benjamin EJ, Bennett D, Bhalla K, Bikbov B, Bin Abdulhak A, Birbeck G, Blyth F, Bolliger I, Boufous S, Bucello C, Burch M, Burney P, Carapetis J, Chen H, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahodwala N, De Leo D, Degenhardt L, Delossantos A, Denenberg J, Des Jarlais DC, Dharmaratne SD, Dorsey ER, Driscoll T, Duber H, Ebel B, Erwin PJ, Espindola P, Ezzati M, Feigin V, Flaxman AD, Forouzanfar MH, Fowkes FG, Franklin R, Fransen M, Freeman MK, Gabriel SE, Gakidou E, Gaspari F, Gillum RF, Gonzalez-Medina D, Halasa YA, Haring D, Harrison JE, Havmoeller R, Hay RJ, Hoen B, Hotez PJ, Hoy D, Jacobsen KH, James SL, Jasrasaria R, Jayaraman S, Johns N, Karthikeyan G, Kassebaum N, Keren A, Khoo JP, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Lipnick M, Lipshultz SE, Ohno SL, Mabweijano J, MacIntyre MF, Mallinger L, March L, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGrath J, Mensah GA, Merriman TR, Michaud C, Miller M, Miller TR, Mock C, Mocumbi AO, Mokdad AA, Moran A, Mulholland K, Nair MN, Naldi L, Narayan KM, Nasseri K, Norman P, O'Donnell M, Omer SB, Ortblad K, Osborne R, Ozgediz D, Pahari B, Pandian JD, Rivero AP, Padilla RP, Perez-Ruiz F, Perico N, Phillips D, Pierce K, Pope CA 3rd, Porrini E, Pourmalek F, Raju M, Ranganathan D, Rehm JT, Rein DB, Remuzzi G, Rivara FP, Roberts T, De León FR, Rosenfeld LC, Rushton L, Sacco RL, Salomon JA, Sampson U, Sanman E, Schwebel DC, Segui-Gomez M, Shepard DS, Singh D, Singleton J, Sliwa K, Smith E, Steer A, Taylor JA, Thomas B, Tleyjeh IM, Towbin JA, Truelsen T, Undurraga EA, Venketasubramanian N, Vijayakumar L, Vos T, Wagner GR, Wang M, Wang W, Watt K, Weinstock MA, Weintraub R, Wilkinson JD, Woolf AD, Wulf S, Yeh PH, Yip P, Zabetian A, Zheng ZJ, Lopez AD, Murray CJ, AlMazroa MA, Memish ZA
Lancet 2012 Dec 15;380(9859):2095-128. doi: 10.1016/S0140-6736(12)61728-0. PMID: 23245604

Clinical prediction guides

Dinnes J, Deeks JJ, Berhane S, Taylor M, Adriano A, Davenport C, Dittrich S, Emperador D, Takwoingi Y, Cunningham J, Beese S, Domen J, Dretzke J, Ferrante di Ruffano L, Harris IM, Price MJ, Taylor-Phillips S, Hooft L, Leeflang MM, McInnes MD, Spijker R, Van den Bruel A; Cochrane COVID-19 Diagnostic Test Accuracy Group
Cochrane Database Syst Rev 2021 Mar 24;3(3):CD013705. doi: 10.1002/14651858.CD013705.pub2. PMID: 33760236Free PMC Article
Njim T, Tanyitiku BS
BMJ Open 2019 Nov 26;9(11):e030793. doi: 10.1136/bmjopen-2019-030793. PMID: 31772089Free PMC Article
De Moraes CM, Wanjiku C, Stanczyk NM, Pulido H, Sims JW, Betz HS, Read AF, Torto B, Mescher MC
Proc Natl Acad Sci U S A 2018 May 29;115(22):5780-5785. Epub 2018 May 14 doi: 10.1073/pnas.1801512115. PMID: 29760095Free PMC Article
Wilson ML
Arch Pathol Lab Med 2013 Jun;137(6):805-11. doi: 10.5858/arpa.2011-0602-RA. PMID: 23721276
O'Meara WP, Hall BF, McKenzie FE
Malar J 2007 Mar 26;6:36. doi: 10.1186/1475-2875-6-36. PMID: 17386083Free PMC Article

Recent systematic reviews

Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, Moraleda C, Rogers L, Daniels K, Green P
Cochrane Database Syst Rev 2022 Feb 1;2(2022) doi: 10.1002/14651858.CD014217. PMID: 36321557Free PMC Article
Cohee LM, Opondo C, Clarke SE, Halliday KE, Cano J, Shipper AG, Barger-Kamate B, Djimde A, Diarra S, Dokras A, Kamya MR, Lutumba P, Ly AB, Nankabirwa JI, Njagi JK, Maiga H, Maiteki-Sebuguzi C, Matangila J, Okello G, Rohner F, Roschnik N, Rouhani S, Sissoko MS, Staedke SG, Thera MA, Turner EL, Van Geertruyden JP, Zimmerman MB, Jukes MCH, Brooker SJ, Allen E, Laufer MK, Chico RM
Lancet Glob Health 2020 Dec;8(12):e1499-e1511. Epub 2020 Oct 22 doi: 10.1016/S2214-109X(20)30325-9. PMID: 33222799Free PMC Article
Shretta R, Avanceña AL, Hatefi A
Malar J 2016 Dec 12;15(1):593. doi: 10.1186/s12936-016-1635-5. PMID: 27955665Free PMC Article
Taylor SM, Parobek CM, Fairhurst RM
Lancet Infect Dis 2012 Jun;12(6):457-68. Epub 2012 Mar 23 doi: 10.1016/S1473-3099(12)70055-5. PMID: 22445352Free PMC Article
Sheehy SH, Angus BJ
BMJ Clin Evid 2011 Mar 7;2011 PMID: 21375787Free PMC Article

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