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Malaria

MedGen UID:
7443
Concept ID:
C0024530
Disease or Syndrome
Synonyms: Fever, Marsh; Fever, Remittent; Infection, Plasmodium; Infections, Plasmodium; Marsh Fever; Paludism; Plasmodium Infection; Plasmodium Infections; Remittent Fever
SNOMED CT: Malaria (61462000); Paludism (61462000); Plasmodiosis (61462000); Disease due to Plasmodiidae (105649009); Disease caused by Plasmodiidae (105649009); Malarial fever (248437004)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0005136
Orphanet: ORPHA673

Definition

A life-threatening parasitic disease caused by <i>Plasmodium</i> (<i>P. </i>) parasites that are transmitted by <i>Anophles</i> mosquito bites to humans and is typically clinically characterized by attacks of fever, headache, chills and vomiting. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalaria
Follow this link to review classifications for Malaria in Orphanet.

Professional guidelines

PubMed

Daily JP, Minuti A, Khan N
JAMA 2022 Aug 2;328(5):460-471. doi: 10.1001/jama.2022.12366. PMID: 35916842
Barber BE, Grigg MJ, Cooper DJ, van Schalkwyk DA, William T, Rajahram GS, Anstey NM
Adv Parasitol 2021;113:45-76. Epub 2021 Sep 1 doi: 10.1016/bs.apar.2021.08.004. PMID: 34620385Free PMC Article
Plewes K, Leopold SJ, Kingston HWF, Dondorp AM
Infect Dis Clin North Am 2019 Mar;33(1):39-60. doi: 10.1016/j.idc.2018.10.002. PMID: 30712767

Recent clinical studies

Etiology

Stanisic DI, Good MF
BioDrugs 2023 Nov;37(6):737-756. Epub 2023 Sep 20 doi: 10.1007/s40259-023-00623-4. PMID: 37728713Free PMC Article
Björkman A, Benn CS, Aaby P, Schapira A
Lancet Infect Dis 2023 Aug;23(8):e318-e322. Epub 2023 Apr 20 doi: 10.1016/S1473-3099(23)00126-3. PMID: 37086747
Shahbodaghi SD, Rathjen NA
Am Fam Physician 2022 Sep;106(3):270-278. PMID: 36126008
Greenwood B, Zongo I, Dicko A, Chandramohan D, Snow RW, Ockenhouse C
Malar J 2022 Mar 9;21(1):77. doi: 10.1186/s12936-022-04098-6. PMID: 35264158Free PMC Article
Rajagopalan A, Ilboudo CM
Pediatr Rev 2019 Mar;40(3):151-153. Epub 2019 Mar 1 doi: 10.1542/pir.2017-0225. PMID: 30824502

Diagnosis

Walter K, John CC
JAMA 2022 Feb 8;327(6):597. doi: 10.1001/jama.2021.21468. PMID: 35133414
Lee YW, Choi JW, Shin EH
Comput Biol Med 2021 Feb;129:104151. Epub 2020 Nov 28 doi: 10.1016/j.compbiomed.2020.104151. PMID: 33290932
Gelbart D
JAAPA 2018 Jul;31(7):49-50. doi: 10.1097/01.JAA.0000533671.03321.f1. PMID: 29957608
Cohee LM, Laufer MK
Pediatr Clin North Am 2017 Aug;64(4):851-866. doi: 10.1016/j.pcl.2017.03.004. PMID: 28734514Free PMC Article
Greenwood BM, Bojang K, Whitty CJ, Targett GA
Lancet 2005 Apr 23-29;365(9469):1487-98. doi: 10.1016/S0140-6736(05)66420-3. PMID: 15850634

Therapy

Meo SA, Klonoff DC, Akram J
Eur Rev Med Pharmacol Sci 2020 Apr;24(8):4539-4547. doi: 10.26355/eurrev_202004_21038. PMID: 32373993
Beeson JG, Kurtovic L, Dobaño C, Opi DH, Chan JA, Feng G, Good MF, Reiling L, Boyle MJ
Sci Transl Med 2019 Jan 9;11(474) doi: 10.1126/scitranslmed.aau1458. PMID: 30626712
Laurens MB
Annu Rev Microbiol 2018 Sep 8;72:273-292. doi: 10.1146/annurev-micro-090817-062427. PMID: 30200856
Abba ML, Patil N, Leupold JH, Saeed MEM, Efferth T, Allgayer H
Cancer Lett 2018 Aug 10;429:11-18. Epub 2018 May 8 doi: 10.1016/j.canlet.2018.05.008. PMID: 29746932
Dramowski A, Frigati L, Rabie H, Cotton M
Infect Disord Drug Targets 2013 Aug;13(4):303-11. doi: 10.2174/1871526513666131129154446. PMID: 24304356

Prognosis

Cohen JM, Okumu F, Moonen B
Sci Transl Med 2022 Jun 29;14(651):eabn3256. doi: 10.1126/scitranslmed.abn3256. PMID: 35767649
Shi T, McAllister DA, O'Brien KL, Simoes EAF, Madhi SA, Gessner BD, Polack FP, Balsells E, Acacio S, Aguayo C, Alassani I, Ali A, Antonio M, Awasthi S, Awori JO, Azziz-Baumgartner E, Baggett HC, Baillie VL, Balmaseda A, Barahona A, Basnet S, Bassat Q, Basualdo W, Bigogo G, Bont L, Breiman RF, Brooks WA, Broor S, Bruce N, Bruden D, Buchy P, Campbell S, Carosone-Link P, Chadha M, Chipeta J, Chou M, Clara W, Cohen C, de Cuellar E, Dang DA, Dash-Yandag B, Deloria-Knoll M, Dherani M, Eap T, Ebruke BE, Echavarria M, de Freitas Lázaro Emediato CC, Fasce RA, Feikin DR, Feng L, Gentile A, Gordon A, Goswami D, Goyet S, Groome M, Halasa N, Hirve S, Homaira N, Howie SRC, Jara J, Jroundi I, Kartasasmita CB, Khuri-Bulos N, Kotloff KL, Krishnan A, Libster R, Lopez O, Lucero MG, Lucion F, Lupisan SP, Marcone DN, McCracken JP, Mejia M, Moisi JC, Montgomery JM, Moore DP, Moraleda C, Moyes J, Munywoki P, Mutyara K, Nicol MP, Nokes DJ, Nymadawa P, da Costa Oliveira MT, Oshitani H, Pandey N, Paranhos-Baccalà G, Phillips LN, Picot VS, Rahman M, Rakoto-Andrianarivelo M, Rasmussen ZA, Rath BA, Robinson A, Romero C, Russomando G, Salimi V, Sawatwong P, Scheltema N, Schweiger B, Scott JAG, Seidenberg P, Shen K, Singleton R, Sotomayor V, Strand TA, Sutanto A, Sylla M, Tapia MD, Thamthitiwat S, Thomas ED, Tokarz R, Turner C, Venter M, Waicharoen S, Wang J, Watthanaworawit W, Yoshida LM, Yu H, Zar HJ, Campbell H, Nair H; RSV Global Epidemiology Network
Lancet 2017 Sep 2;390(10098):946-958. Epub 2017 Jul 7 doi: 10.1016/S0140-6736(17)30938-8. PMID: 28689664Free PMC Article
Fasanmade OA, Dagogo-Jack S
Ann Glob Health 2015 Nov-Dec;81(6):821-9. doi: 10.1016/j.aogh.2015.12.012. PMID: 27108149
RTS,S Clinical Trials Partnership
Lancet 2015 Jul 4;386(9988):31-45. Epub 2015 Apr 23 doi: 10.1016/S0140-6736(15)60721-8. PMID: 25913272Free PMC Article
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Barker-Collo S, Bartels DH, Bell ML, Benjamin EJ, Bennett D, Bhalla K, Bikbov B, Bin Abdulhak A, Birbeck G, Blyth F, Bolliger I, Boufous S, Bucello C, Burch M, Burney P, Carapetis J, Chen H, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahodwala N, De Leo D, Degenhardt L, Delossantos A, Denenberg J, Des Jarlais DC, Dharmaratne SD, Dorsey ER, Driscoll T, Duber H, Ebel B, Erwin PJ, Espindola P, Ezzati M, Feigin V, Flaxman AD, Forouzanfar MH, Fowkes FG, Franklin R, Fransen M, Freeman MK, Gabriel SE, Gakidou E, Gaspari F, Gillum RF, Gonzalez-Medina D, Halasa YA, Haring D, Harrison JE, Havmoeller R, Hay RJ, Hoen B, Hotez PJ, Hoy D, Jacobsen KH, James SL, Jasrasaria R, Jayaraman S, Johns N, Karthikeyan G, Kassebaum N, Keren A, Khoo JP, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Lipnick M, Lipshultz SE, Ohno SL, Mabweijano J, MacIntyre MF, Mallinger L, March L, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGrath J, Mensah GA, Merriman TR, Michaud C, Miller M, Miller TR, Mock C, Mocumbi AO, Mokdad AA, Moran A, Mulholland K, Nair MN, Naldi L, Narayan KM, Nasseri K, Norman P, O'Donnell M, Omer SB, Ortblad K, Osborne R, Ozgediz D, Pahari B, Pandian JD, Rivero AP, Padilla RP, Perez-Ruiz F, Perico N, Phillips D, Pierce K, Pope CA 3rd, Porrini E, Pourmalek F, Raju M, Ranganathan D, Rehm JT, Rein DB, Remuzzi G, Rivara FP, Roberts T, De León FR, Rosenfeld LC, Rushton L, Sacco RL, Salomon JA, Sampson U, Sanman E, Schwebel DC, Segui-Gomez M, Shepard DS, Singh D, Singleton J, Sliwa K, Smith E, Steer A, Taylor JA, Thomas B, Tleyjeh IM, Towbin JA, Truelsen T, Undurraga EA, Venketasubramanian N, Vijayakumar L, Vos T, Wagner GR, Wang M, Wang W, Watt K, Weinstock MA, Weintraub R, Wilkinson JD, Woolf AD, Wulf S, Yeh PH, Yip P, Zabetian A, Zheng ZJ, Lopez AD, Murray CJ, AlMazroa MA, Memish ZA
Lancet 2012 Dec 15;380(9859):2095-128. doi: 10.1016/S0140-6736(12)61728-0. PMID: 23245604Free PMC Article

Clinical prediction guides

Dinnes J, Deeks JJ, Berhane S, Taylor M, Adriano A, Davenport C, Dittrich S, Emperador D, Takwoingi Y, Cunningham J, Beese S, Domen J, Dretzke J, Ferrante di Ruffano L, Harris IM, Price MJ, Taylor-Phillips S, Hooft L, Leeflang MM, McInnes MD, Spijker R, Van den Bruel A; Cochrane COVID-19 Diagnostic Test Accuracy Group
Cochrane Database Syst Rev 2021 Mar 24;3(3):CD013705. doi: 10.1002/14651858.CD013705.pub2. PMID: 33760236Free PMC Article
De Moraes CM, Wanjiku C, Stanczyk NM, Pulido H, Sims JW, Betz HS, Read AF, Torto B, Mescher MC
Proc Natl Acad Sci U S A 2018 May 29;115(22):5780-5785. Epub 2018 May 14 doi: 10.1073/pnas.1801512115. PMID: 29760095Free PMC Article
Taylor SM, Molyneux ME, Simel DL, Meshnick SR, Juliano JJ
JAMA 2010 Nov 10;304(18):2048-56. Epub 2010 Nov 5 doi: 10.1001/jama.2010.1578. PMID: 21057136
Bell D, Perkins MD
Trans R Soc Trop Med Hyg 2008 Nov;102(11):1064-6. Epub 2008 Jun 30 doi: 10.1016/j.trstmh.2008.05.007. PMID: 18586290
O'Meara WP, Hall BF, McKenzie FE
Malar J 2007 Mar 26;6:36. doi: 10.1186/1475-2875-6-36. PMID: 17386083Free PMC Article

Recent systematic reviews

Newby G, Cotter C, Roh ME, Harvard K, Bennett A, Hwang J, Chitnis N, Fine S, Stresman G, Chen I, Gosling R, Hsiang MS
Malar J 2023 Sep 3;22(1):254. doi: 10.1186/s12936-023-04670-8. PMID: 37661286Free PMC Article
Chu CS, Hwang J
Expert Opin Drug Saf 2021 Mar;20(3):349-362. Epub 2021 Jan 4 doi: 10.1080/14740338.2021.1859476. PMID: 33306921Free PMC Article
Cohee LM, Opondo C, Clarke SE, Halliday KE, Cano J, Shipper AG, Barger-Kamate B, Djimde A, Diarra S, Dokras A, Kamya MR, Lutumba P, Ly AB, Nankabirwa JI, Njagi JK, Maiga H, Maiteki-Sebuguzi C, Matangila J, Okello G, Rohner F, Roschnik N, Rouhani S, Sissoko MS, Staedke SG, Thera MA, Turner EL, Van Geertruyden JP, Zimmerman MB, Jukes MCH, Brooker SJ, Allen E, Laufer MK, Chico RM
Lancet Glob Health 2020 Dec;8(12):e1499-e1511. Epub 2020 Oct 22 doi: 10.1016/S2214-109X(20)30325-9. PMID: 33222799Free PMC Article
Ippolito MM, Denny JE, Langelier C, Sears CL, Schmidt NW
Clin Infect Dis 2018 Nov 28;67(12):1831-1839. doi: 10.1093/cid/ciy374. PMID: 29701835Free PMC Article
Sheehy SH, Angus BJ
BMJ Clin Evid 2011 Mar 7;2011 PMID: 21375787Free PMC Article

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