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Localized Malignant Mesothelioma

MedGen UID:
75866
•Concept ID:
C0278751
•
Neoplastic Process

Definition

A malignant mesothelioma with the gross appearance of a circumscribed serosal lesion and the microscopic appearance of diffuse malignant mesothelioma, without evidence of diffuse spread. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocalized Malignant Mesothelioma

Professional guidelines

PubMed

Chinese expert consensus on the diagnosis and treatment of malignant pleural mesothelioma.
Wang Q, Xu C, Wang W, Zhang Y, Li Z, Song Z, Wang J, Yu J, Liu J, Zhang S, Cai X, Li W, Zhan P, Liu H, Lv T, Miao L, Min L, Li J, Liu B, Yuan J, Jiang Z, Lin G, Chen X, Pu X, Rao C, Lv D, Yu Z, Li X, Tang C, Zhou C, Zhang J, Guo H, Chu Q, Meng R, Liu X, Wu J, Hu X, Zhou J, Zhu Z, Chen X, Pan W, Pang F, Zhang W, Jian Q, Wang K, Wang L, Zhu Y, Yang G, Lin X, Cai J, Feng H, Wang L, Du Y, Yao W, Shi X, Niu X, Yuan D, Yao Y, Huang J, Wang X, Zhang Y, Sun P, Wang H, Ye M, Wang D, Wang Z, Hao Y, Wang Z, Wan B, Lv D, Yu J, Kang J, Zhang J, Zhang C, Wu L, Shi L, Ye L, Wang G, Wang Y, Gao F, Huang J, Wang G, Wei J, Huang L, Li B, Zhang Z, Li Z, Liu Y, Li Y, Liu Z, Yang N, Wu L, Wang Q, Huang W, Hong Z, Wang G, Qu F, Fang M, Fang Y, Zhu X, Du K, Ji J, Shen Y, Chen J, Zhang Y, Ma S, Lu Y, Song Y, Liu A, Zhong W, Fang W
Thorac Cancer 2023 Sep;14(26):2715-2731. Epub 2023 Jul 17 doi: 10.1111/1759-7714.15022. PMID: 37461124Free PMC Article
Guidelines for Pathologic Diagnosis of Malignant Mesothelioma 2017 Update of the Consensus Statement From the International Mesothelioma Interest Group.
Husain AN, Colby TV, Ordóñez NG, Allen TC, Attanoos RL, Beasley MB, Butnor KJ, Chirieac LR, Churg AM, Dacic S, Galateau-Sallé F, Gibbs A, Gown AM, Krausz T, Litzky LA, Marchevsky A, Nicholson AG, Roggli VL, Sharma AK, Travis WD, Walts AE, Wick MR
Arch Pathol Lab Med 2018 Jan;142(1):89-108. Epub 2017 Jul 7 doi: 10.5858/arpa.2017-0124-RA. PMID: 28686500
Multimodality management of malignant pleural mesothelioma: introduction.
Sugarbaker DJ
Semin Thorac Cardiovasc Surg 2009 Summer;21(2):95-6. doi: 10.1053/j.semtcvs.2009.07.005. PMID: 19822279

Recent clinical studies

Etiology

Solid papillary mesothelial tumor.
Churg A, Le Stang N, Dacic S, Pissaloux D, Begueret H, Dartigues P, Giusiano-Courcambeck S, Sequeiros R, Pairon JC, Tirode F, Galateau-Sallé F
Mod Pathol 2022 Jan;35(1):69-76. Epub 2021 Sep 3 doi: 10.1038/s41379-021-00899-3. PMID: 34480081
Cutaneous recurrence of malignant mesothelioma of the tunica vaginalis testis: a rare case report.
Priester P, Kopecký J, Prošvicová J, Petera J, Zoul Z, Slováček L
Onkologie 2012;35(1-2):46-8. Epub 2012 Jan 23 doi: 10.1159/000335884. PMID: 22310346
Primary malignant mesothelioma developed in liver.
Kim DS, Lee SG, Jun SY, Kim KW, Ha TY, Kim KK
Hepatogastroenterology 2008 May-Jun;55(84):1081-4. PMID: 18705333
Clinical behavior of solitary fibrous tumors of the pleura. An immunohistochemical study.
Brozzetti S, D'Andrea N, Limiti MR, Pisanelli MC, De Angelis R, Cavallaro A
Anticancer Res 2000 Nov-Dec;20(6C):4701-6. PMID: 11205204

Diagnosis

Solid papillary mesothelial tumor.
Churg A, Le Stang N, Dacic S, Pissaloux D, Begueret H, Dartigues P, Giusiano-Courcambeck S, Sequeiros R, Pairon JC, Tirode F, Galateau-Sallé F
Mod Pathol 2022 Jan;35(1):69-76. Epub 2021 Sep 3 doi: 10.1038/s41379-021-00899-3. PMID: 34480081
Localized malignant mesothelioma, an unusual and poorly characterized neoplasm of serosal origin: best current evidence from the literature and the International Mesothelioma Panel.
Marchevsky AM, Khoor A, Walts AE, Nicholson AG, Zhang YZ, Roggli V, Carney J, Roden AC, Tazelaar HD, Larsen BT, LeStang N, Chirieac LR, Klebe S, Tsao MS, De Perrot M, Pierre A, Hwang DM, Hung YP, Mino-Kenudson M, Travis W, Sauter J, Beasley MB, Galateau-Sallé F
Mod Pathol 2020 Feb;33(2):281-296. Epub 2019 Sep 4 doi: 10.1038/s41379-019-0352-3. PMID: 31485011Free PMC Article
Revisiting localized malignant mesothelioma.
Mann S, Khawar S, Moran C, Kalhor N
Ann Diagn Pathol 2019 Apr;39:74-77. Epub 2019 Feb 19 doi: 10.1016/j.anndiagpath.2019.02.014. PMID: 30798074
Localized malignant mesothelioma.
Allen TC, Cagle PT, Churg AM, Colby TV, Gibbs AR, Hammar SP, Corson JM, Grimes MM, Ordonez NG, Roggli V, Travis WD, Wick MR
Am J Surg Pathol 2005 Jul;29(7):866-73. doi: 10.1097/01.pas.0000165529.78945.dc. PMID: 15958850
Localized pleural malignant mesothelioma.
Erkiliç S, Sari I, Tunçözgür B
Pathol Int 2001 Oct;51(10):812-5. doi: 10.1046/j.1440-1827.2001.01279.x. PMID: 11881736

Therapy

Clinical and pathological observation of conversion therapy for malignant peritoneal mesothelioma: a case report and literature review.
Deng M, Zhang X, Xu C, Luo R, Chen L, Zhou Y, Hou Y
Pathol Oncol Res 2023;29:1611577. Epub 2024 Jan 8 doi: 10.3389/pore.2023.1611577. PMID: 38273860Free PMC Article
A Case of Mediastinal Localized Malignant Pleural Mesothelioma Successfully Treated by Chemotherapy and Conversion Surgery.
Maki Y, Kiriyama Y, Ueno T, Suehisa H, Shigematsu H, Saeki K, Harada D, Kozuki T, Teramoto N, Yamashita M
Acta Med Okayama 2022 Jun;76(3):343-347. doi: 10.18926/AMO/63746. PMID: 35790367
Revisiting localized malignant mesothelioma.
Mann S, Khawar S, Moran C, Kalhor N
Ann Diagn Pathol 2019 Apr;39:74-77. Epub 2019 Feb 19 doi: 10.1016/j.anndiagpath.2019.02.014. PMID: 30798074
Patterns of failure following surgical resection for malignant pleural mesothelioma.
Jänne PA, Baldini EH
Thorac Surg Clin 2004 Nov;14(4):567-73. doi: 10.1016/j.thorsurg.2004.06.006. PMID: 15559064
Localized malignant mesothelioma. A clinicopathologic and flow cytometric study.
Crotty TB, Myers JL, Katzenstein AL, Tazelaar HD, Swensen SJ, Churg A
Am J Surg Pathol 1994 Apr;18(4):357-63. PMID: 7511353

Prognosis

Solid papillary mesothelial tumor.
Churg A, Le Stang N, Dacic S, Pissaloux D, Begueret H, Dartigues P, Giusiano-Courcambeck S, Sequeiros R, Pairon JC, Tirode F, Galateau-Sallé F
Mod Pathol 2022 Jan;35(1):69-76. Epub 2021 Sep 3 doi: 10.1038/s41379-021-00899-3. PMID: 34480081
Localized malignant mesothelioma, an unusual and poorly characterized neoplasm of serosal origin: best current evidence from the literature and the International Mesothelioma Panel.
Marchevsky AM, Khoor A, Walts AE, Nicholson AG, Zhang YZ, Roggli V, Carney J, Roden AC, Tazelaar HD, Larsen BT, LeStang N, Chirieac LR, Klebe S, Tsao MS, De Perrot M, Pierre A, Hwang DM, Hung YP, Mino-Kenudson M, Travis W, Sauter J, Beasley MB, Galateau-Sallé F
Mod Pathol 2020 Feb;33(2):281-296. Epub 2019 Sep 4 doi: 10.1038/s41379-019-0352-3. PMID: 31485011Free PMC Article
Revisiting localized malignant mesothelioma.
Mann S, Khawar S, Moran C, Kalhor N
Ann Diagn Pathol 2019 Apr;39:74-77. Epub 2019 Feb 19 doi: 10.1016/j.anndiagpath.2019.02.014. PMID: 30798074
What is the survival after surgery for localized malignant pleural mesothelioma?
Gelvez-Zapata SM, Gaffney D, Scarci M, Coonar AS
Interact Cardiovasc Thorac Surg 2013 Apr;16(4):533-7. Epub 2013 Jan 17 doi: 10.1093/icvts/ivs542. PMID: 23328002Free PMC Article
Localized malignant mesothelioma.
Allen TC, Cagle PT, Churg AM, Colby TV, Gibbs AR, Hammar SP, Corson JM, Grimes MM, Ordonez NG, Roggli V, Travis WD, Wick MR
Am J Surg Pathol 2005 Jul;29(7):866-73. doi: 10.1097/01.pas.0000165529.78945.dc. PMID: 15958850

Clinical prediction guides

Clinical and pathological observation of conversion therapy for malignant peritoneal mesothelioma: a case report and literature review.
Deng M, Zhang X, Xu C, Luo R, Chen L, Zhou Y, Hou Y
Pathol Oncol Res 2023;29:1611577. Epub 2024 Jan 8 doi: 10.3389/pore.2023.1611577. PMID: 38273860Free PMC Article
A Case of Mediastinal Localized Malignant Pleural Mesothelioma Successfully Treated by Chemotherapy and Conversion Surgery.
Maki Y, Kiriyama Y, Ueno T, Suehisa H, Shigematsu H, Saeki K, Harada D, Kozuki T, Teramoto N, Yamashita M
Acta Med Okayama 2022 Jun;76(3):343-347. doi: 10.18926/AMO/63746. PMID: 35790367
Localized malignant mesothelioma, an unusual and poorly characterized neoplasm of serosal origin: best current evidence from the literature and the International Mesothelioma Panel.
Marchevsky AM, Khoor A, Walts AE, Nicholson AG, Zhang YZ, Roggli V, Carney J, Roden AC, Tazelaar HD, Larsen BT, LeStang N, Chirieac LR, Klebe S, Tsao MS, De Perrot M, Pierre A, Hwang DM, Hung YP, Mino-Kenudson M, Travis W, Sauter J, Beasley MB, Galateau-Sallé F
Mod Pathol 2020 Feb;33(2):281-296. Epub 2019 Sep 4 doi: 10.1038/s41379-019-0352-3. PMID: 31485011Free PMC Article
Patterns of failure following surgical resection for malignant pleural mesothelioma.
Jänne PA, Baldini EH
Thorac Surg Clin 2004 Nov;14(4):567-73. doi: 10.1016/j.thorsurg.2004.06.006. PMID: 15559064
Localized malignant mesothelioma. A clinicopathologic and flow cytometric study.
Crotty TB, Myers JL, Katzenstein AL, Tazelaar HD, Swensen SJ, Churg A
Am J Surg Pathol 1994 Apr;18(4):357-63. PMID: 7511353

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