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Unresectable Gallbladder Carcinoma

MedGen UID:
75874
•Concept ID:
C0278807
•
Neoplastic Process
Synonyms: Gallbladder Cancer Unresectable; Gallbladder Carcinoma Unresectable; Unresectable Cancer of Gallbladder; Unresectable Cancer of the Gallbladder; Unresectable Gallbladder Cancer

Definition

A carcinoma that arises from the gallbladder and it is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Gallbladder Carcinoma

Professional guidelines

PubMed

Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Benson AB, D'Angelica MI, Abbott DE, Anaya DA, Anders R, Are C, Bachini M, Borad M, Brown D, Burgoyne A, Chahal P, Chang DT, Cloyd J, Covey AM, Glazer ES, Goyal L, Hawkins WG, Iyer R, Jacob R, Kelley RK, Kim R, Levine M, Palta M, Park JO, Raman S, Reddy S, Sahai V, Schefter T, Singh G, Stein S, Vauthey JN, Venook AP, Yopp A, McMillian NR, Hochstetler C, Darlow SD
J Natl Compr Canc Netw 2021 May 1;19(5):541-565. doi: 10.6004/jnccn.2021.0022. PMID: 34030131
Multimodality Management of Localized Biliary Cancer.
Ashai N, Prasad P, Rajdev L
Curr Treat Options Oncol 2019 May 29;20(7):58. doi: 10.1007/s11864-019-0655-0. PMID: 31144050
Current management of gallbladder carcinoma.
Zhu AX, Hong TS, Hezel AF, Kooby DA
Oncologist 2010;15(2):168-81. Epub 2010 Feb 10 doi: 10.1634/theoncologist.2009-0302. PMID: 20147507Free PMC Article

Recent clinical studies

Etiology

Is external palliative radiotherapy for gallbladder carcinoma effective?
Eleftheriadis N, Pistevou-Gombaki K, Plataniotis G, Sofroniadis I, Kouloulias V
Onkologie 2001 Dec;24(6):581-4. doi: 10.1159/000055147. PMID: 11799314
Palliative treatment with metallic stents for unresectable gallbladder carcinoma involving the portal vein and bile duct.
Tanaka Ji, Andoh H, Yoshioka M, Furuya T, Asanuma Y, Koyama K
J Hepatobiliary Pancreat Surg 2000;7(3):331-5. doi: 10.1007/s005340070058. PMID: 10982636

Diagnosis

Is external palliative radiotherapy for gallbladder carcinoma effective?
Eleftheriadis N, Pistevou-Gombaki K, Plataniotis G, Sofroniadis I, Kouloulias V
Onkologie 2001 Dec;24(6):581-4. doi: 10.1159/000055147. PMID: 11799314
Palliative treatment with metallic stents for unresectable gallbladder carcinoma involving the portal vein and bile duct.
Tanaka Ji, Andoh H, Yoshioka M, Furuya T, Asanuma Y, Koyama K
J Hepatobiliary Pancreat Surg 2000;7(3):331-5. doi: 10.1007/s005340070058. PMID: 10982636

Therapy

Is external palliative radiotherapy for gallbladder carcinoma effective?
Eleftheriadis N, Pistevou-Gombaki K, Plataniotis G, Sofroniadis I, Kouloulias V
Onkologie 2001 Dec;24(6):581-4. doi: 10.1159/000055147. PMID: 11799314
A phase II study of gemcitabine in gallbladder carcinoma.
Gallardo JO, Rubio B, Fodor M, Orlandi L, Yáñez M, Gamargo C, Ahumada M
Ann Oncol 2001 Oct;12(10):1403-6. doi: 10.1023/a:1012543223020. PMID: 11762811

Prognosis

Is external palliative radiotherapy for gallbladder carcinoma effective?
Eleftheriadis N, Pistevou-Gombaki K, Plataniotis G, Sofroniadis I, Kouloulias V
Onkologie 2001 Dec;24(6):581-4. doi: 10.1159/000055147. PMID: 11799314
Palliative treatment with metallic stents for unresectable gallbladder carcinoma involving the portal vein and bile duct.
Tanaka Ji, Andoh H, Yoshioka M, Furuya T, Asanuma Y, Koyama K
J Hepatobiliary Pancreat Surg 2000;7(3):331-5. doi: 10.1007/s005340070058. PMID: 10982636

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