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Biliary System Disorder

MedGen UID:
476757
•Concept ID:
C3275124
•
Disease or Syndrome
Synonyms: Biliary Disease; Biliary Disorder

Definition

A non-neoplastic or neoplastic disorder that affects the intrahepatic or extrahepatic bile ducts or the gallbladder. Representative examples of non-neoplastic disorders include cholangitis and cholecystitis. Representative examples of neoplastic disorders include extrahepatic bile duct adenoma, intrahepatic and extrahepatic cholangiocarcinoma, and gallbladder carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBiliary System Disorder

Professional guidelines

PubMed

Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos).
Yokoe M, Hata J, Takada T, Strasberg SM, Asbun HJ, Wakabayashi G, Kozaka K, Endo I, Deziel DJ, Miura F, Okamoto K, Hwang TL, Huang WS, Ker CG, Chen MF, Han HS, Yoon YS, Choi IS, Yoon DS, Noguchi Y, Shikata S, Ukai T, Higuchi R, Gabata T, Mori Y, Iwashita Y, Hibi T, Jagannath P, Jonas E, Liau KH, Dervenis C, Gouma DJ, Cherqui D, Belli G, Garden OJ, Giménez ME, de Santibañes E, Suzuki K, Umezawa A, Supe AN, Pitt HA, Singh H, Chan ACW, Lau WY, Teoh AYB, Honda G, Sugioka A, Asai K, Gomi H, Itoi T, Kiriyama S, Yoshida M, Mayumi T, Matsumura N, Tokumura H, Kitano S, Hirata K, Inui K, Sumiyama Y, Yamamoto M
J Hepatobiliary Pancreat Sci 2018 Jan;25(1):41-54. Epub 2018 Jan 9 doi: 10.1002/jhbp.515. PMID: 29032636
Pathogenesis, diagnosis, and management of cholangiocarcinoma.
Ilyas SI, Gores GJ
Gastroenterology 2013 Dec;145(6):1215-29. Epub 2013 Oct 15 doi: 10.1053/j.gastro.2013.10.013. PMID: 24140396Free PMC Article
IAP/APA evidence-based guidelines for the management of acute pancreatitis.
Working Group IAP/APA Acute Pancreatitis Guidelines
Pancreatology 2013 Jul-Aug;13(4 Suppl 2):e1-15. doi: 10.1016/j.pan.2013.07.063. PMID: 24054878

Recent clinical studies

Etiology

Cholangiocarcinoma.
Brindley PJ, Bachini M, Ilyas SI, Khan SA, Loukas A, Sirica AE, Teh BT, Wongkham S, Gores GJ
Nat Rev Dis Primers 2021 Sep 9;7(1):65. doi: 10.1038/s41572-021-00300-2. PMID: 34504109Free PMC Article
International consensus statements for endoscopic management of distal biliary stricture.
Nakai Y, Isayama H, Wang HP, Rerknimitr R, Khor C, Yasuda I, Kogure H, Moon JH, Lau J, Lakhtakia S, Ratanachu-Ek T, Seo DW, Lee DK, Makmun D, Dy F, Liao WC, Draganov PV, Almadi M, Irisawa A, Katanuma A, Kitano M, Ryozawa S, Fujisawa T, Wallace MB, Itoi T, Devereaux B
J Gastroenterol Hepatol 2020 Jun;35(6):967-979. Epub 2020 Jan 10 doi: 10.1111/jgh.14955. PMID: 31802537Free PMC Article
Acute cholangitis: Diagnosis and management.
Sokal A, Sauvanet A, Fantin B, de Lastours V
J Visc Surg 2019 Dec;156(6):515-525. Epub 2019 Jun 24 doi: 10.1016/j.jviscsurg.2019.05.007. PMID: 31248783
Pathophysiological consequences of obstructive jaundice and perioperative management.
Pavlidis ET, Pavlidis TE
Hepatobiliary Pancreat Dis Int 2018 Feb;17(1):17-21. Epub 2018 Jan 31 doi: 10.1016/j.hbpd.2018.01.008. PMID: 29428098
Gallstones.
Lammert F, Gurusamy K, Ko CW, Miquel JF, Méndez-Sánchez N, Portincasa P, van Erpecum KJ, van Laarhoven CJ, Wang DQ
Nat Rev Dis Primers 2016 Apr 28;2:16024. doi: 10.1038/nrdp.2016.24. PMID: 27121416

Diagnosis

International consensus statements for endoscopic management of distal biliary stricture.
Nakai Y, Isayama H, Wang HP, Rerknimitr R, Khor C, Yasuda I, Kogure H, Moon JH, Lau J, Lakhtakia S, Ratanachu-Ek T, Seo DW, Lee DK, Makmun D, Dy F, Liao WC, Draganov PV, Almadi M, Irisawa A, Katanuma A, Kitano M, Ryozawa S, Fujisawa T, Wallace MB, Itoi T, Devereaux B
J Gastroenterol Hepatol 2020 Jun;35(6):967-979. Epub 2020 Jan 10 doi: 10.1111/jgh.14955. PMID: 31802537Free PMC Article
Acute cholangitis: Diagnosis and management.
Sokal A, Sauvanet A, Fantin B, de Lastours V
J Visc Surg 2019 Dec;156(6):515-525. Epub 2019 Jun 24 doi: 10.1016/j.jviscsurg.2019.05.007. PMID: 31248783
Hepatobiliary and pancreatic ascariasis.
Khuroo MS, Rather AA, Khuroo NS, Khuroo MS
World J Gastroenterol 2016 Sep 7;22(33):7507-17. doi: 10.3748/wjg.v22.i33.7507. PMID: 27672273Free PMC Article
Gallstones.
Lammert F, Gurusamy K, Ko CW, Miquel JF, Méndez-Sánchez N, Portincasa P, van Erpecum KJ, van Laarhoven CJ, Wang DQ
Nat Rev Dis Primers 2016 Apr 28;2:16024. doi: 10.1038/nrdp.2016.24. PMID: 27121416
Nanoparticle-liver interactions: Cellular uptake and hepatobiliary elimination.
Zhang YN, Poon W, Tavares AJ, McGilvray ID, Chan WCW
J Control Release 2016 Oct 28;240:332-348. Epub 2016 Jan 13 doi: 10.1016/j.jconrel.2016.01.020. PMID: 26774224

Therapy

Integrating cytotoxic, targeted and immune therapies for cholangiocarcinoma.
Merters J, Lamarca A
J Hepatol 2023 Mar;78(3):652-657. Epub 2022 Nov 15 doi: 10.1016/j.jhep.2022.11.005. PMID: 36400328
Gallbladder Dyskinesia.
Presti ME, Elwing JE, Sayuk GS
South Med J 2022 Nov;115(11):838-841. doi: 10.14423/SMJ.0000000000001466. PMID: 36318951
The Landmark Series: Hilar Cholangiocarcinoma.
Soares KC, Jarnagin WR
Ann Surg Oncol 2021 Aug;28(8):4158-4170. Epub 2021 Apr 7 doi: 10.1245/s10434-021-09871-6. PMID: 33829358Free PMC Article
Acute cholangitis: Diagnosis and management.
Sokal A, Sauvanet A, Fantin B, de Lastours V
J Visc Surg 2019 Dec;156(6):515-525. Epub 2019 Jun 24 doi: 10.1016/j.jviscsurg.2019.05.007. PMID: 31248783
Pathophysiological consequences of obstructive jaundice and perioperative management.
Pavlidis ET, Pavlidis TE
Hepatobiliary Pancreat Dis Int 2018 Feb;17(1):17-21. Epub 2018 Jan 31 doi: 10.1016/j.hbpd.2018.01.008. PMID: 29428098

Prognosis

Imaging of benign biliary pathologies.
Sundaram KM, Morgan MA, Itani M, Thompson W
Abdom Radiol (NY) 2023 Jan;48(1):106-126. Epub 2022 Feb 24 doi: 10.1007/s00261-022-03440-5. PMID: 35201397
Acute cholangitis: Diagnosis and management.
Sokal A, Sauvanet A, Fantin B, de Lastours V
J Visc Surg 2019 Dec;156(6):515-525. Epub 2019 Jun 24 doi: 10.1016/j.jviscsurg.2019.05.007. PMID: 31248783
Global trends in mortality from intrahepatic and extrahepatic cholangiocarcinoma.
Bertuccio P, Malvezzi M, Carioli G, Hashim D, Boffetta P, El-Serag HB, La Vecchia C, Negri E
J Hepatol 2019 Jul;71(1):104-114. Epub 2019 Mar 23 doi: 10.1016/j.jhep.2019.03.013. PMID: 30910538
Benign biliary diseases.
Bali MA, Pezzullo M, Pace E, Morone M
Eur J Radiol 2017 Aug;93:217-228. Epub 2017 May 27 doi: 10.1016/j.ejrad.2017.05.035. PMID: 28668418
Surgical management of biliary tract cancers.
Fairweather M, Balachandran VP, D'Angelica MI
Chin Clin Oncol 2016 Oct;5(5):63. doi: 10.21037/cco.2016.10.03. PMID: 27829277

Clinical prediction guides

IgG4-related autoimmune liver disease.
Capurso G, Pedica F, Palumbo D, Della-Torre E
Minerva Gastroenterol (Torino) 2023 Mar;69(1):23-49. Epub 2020 Dec 3 doi: 10.23736/S2724-5895.20.02794-4. PMID: 33267565
Pediatric biliary disorders: Multimodality imaging evaluation with clinicopathologic correlation.
Aboughalia H, Kim HH, Dick AAS, Pacheco MC, Cilley RE, Iyer RS
Clin Imaging 2021 Jul;75:34-45. Epub 2021 Jan 21 doi: 10.1016/j.clinimag.2021.01.006. PMID: 33493735
Acute cholangitis: Diagnosis and management.
Sokal A, Sauvanet A, Fantin B, de Lastours V
J Visc Surg 2019 Dec;156(6):515-525. Epub 2019 Jun 24 doi: 10.1016/j.jviscsurg.2019.05.007. PMID: 31248783
Biliary interventions using single-operator cholangioscopy.
Navaneethan U, Moon JH, Itoi T
Dig Endosc 2019 Sep;31(5):517-526. Epub 2019 Mar 21 doi: 10.1111/den.13361. PMID: 30689238
Percutaneous Transhepatic Cholangioscopy.
Ahmed S, Schlachter TR, Hong K
Tech Vasc Interv Radiol 2015 Dec;18(4):201-9. Epub 2015 Jul 15 doi: 10.1053/j.tvir.2015.07.003. PMID: 26615160

Recent systematic reviews

Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD).
Storebø OJ, Storm MRO, Pereira Ribeiro J, Skoog M, Groth C, Callesen HE, Schaug JP, Darling Rasmussen P, Huus CL, Zwi M, Kirubakaran R, Simonsen E, Gluud C
Cochrane Database Syst Rev 2023 Mar 27;3(3):CD009885. doi: 10.1002/14651858.CD009885.pub3. PMID: 36971690Free PMC Article
Management of symptomatic cholelithiasis: a systematic review.
Shenoy R, Kirkland P, Hadaya JE, Tranfield MW, DeVirgilio M, Russell MM, Maggard-Gibbons M
Syst Rev 2022 Dec 12;11(1):267. doi: 10.1186/s13643-022-02135-8. PMID: 36510302Free PMC Article
Extrapelvic Endometriosis: A Systematic Review.
Andres MP, Arcoverde FVL, Souza CCC, Fernandes LFC, Abrão MS, Kho RM
J Minim Invasive Gynecol 2020 Feb;27(2):373-389. Epub 2019 Oct 13 doi: 10.1016/j.jmig.2019.10.004. PMID: 31618674
Long-Term Impact of Iatrogenic Bile Duct Injury.
Schreuder AM, Busch OR, Besselink MG, Ignatavicius P, Gulbinas A, Barauskas G, Gouma DJ, van Gulik TM
Dig Surg 2020;37(1):10-21. Epub 2019 Jan 17 doi: 10.1159/000496432. PMID: 30654363Free PMC Article
Acute cholecystitis.
Halpin V
BMJ Clin Evid 2014 Aug 20;2014 PMID: 25144428Free PMC Article

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