U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hepatobiliary disorder

MedGen UID:
82758
Concept ID:
C0267792
Disease or Syndrome
Synonym: Hepatobiliary disease
 
Monarch Initiative: MONDO:0002515

Definition

A non-neoplastic or neoplastic disorder that affects the liver, bile ducts, and gallbladder. Representative examples of non-neoplastic disorders include hepatitis, cirrhosis, cholangitis, and cholecystitis. Representative examples of neoplastic disorders include hepatocellular adenoma, hepatocellular carcinoma, and cholangiocarcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHepatobiliary disorder

Professional guidelines

PubMed

Hussain AB, Samuel R, Hegade VS, Jones DE, Reynolds NJ
Br J Dermatol 2019 Dec;181(6):1138-1145. Epub 2019 Jul 28 doi: 10.1111/bjd.17933. PMID: 30920648
Huesmann M, Huesmann T, Osada N, Phan NQ, Kremer AE, Ständer S
J Dtsch Dermatol Ges 2013 Feb;11(2):158-68. Epub 2012 Nov 29 doi: 10.1111/j.1610-0387.2012.08028.x. PMID: 23190476
Wiesner RH, Ludwig J, LaRusso NF, MacCarty RL
Semin Liver Dis 1985 Aug;5(3):241-53. doi: 10.1055/s-2008-1040621. PMID: 3901273

Recent clinical studies

Etiology

Cacabelos R, Naidoo V, Martínez-Iglesias O, Corzo L, Cacabelos N, Pego R, Carril JC
Methods Mol Biol 2022;2547:275-387. doi: 10.1007/978-1-0716-2573-6_13. PMID: 36068470
Nekaeva ES, Bolshakova AE, Malysheva ES, Galova EA, Makarova EV, Nekrasova TA, Polyakova IV, Bedretdinova ZS, Belikina DV, Lavrenyuk AA, Fomin IV
Sovrem Tekhnologii Med 2021;13(4):16-24. Epub 2021 Aug 28 doi: 10.17691/stm2021.13.4.02. PMID: 34603760Free PMC Article
Alvarenga LR, Sandy NS, Gomez GS, Hessel G, DE Tommaso AMA, Bellomo-Brandão MÂ
Arq Gastroenterol 2021 Apr-Jun;58(2):227-233. doi: 10.1590/S0004-2803.202100000-41. PMID: 34287532
Larusso NF
P R Health Sci J 1999 Mar;18(1):11-7. PMID: 10343981
Wiesner RH, Ludwig J, LaRusso NF, MacCarty RL
Semin Liver Dis 1985 Aug;5(3):241-53. doi: 10.1055/s-2008-1040621. PMID: 3901273

Diagnosis

Mahfouz M, Martin P, Carrion AF
Clin Liver Dis 2019 May;23(2):191-208. Epub 2019 Feb 26 doi: 10.1016/j.cld.2018.12.003. PMID: 30947871
Terziroli Beretta-Piccoli B, Vergani D, Mieli-Vergani G
J Autoimmun 2018 Dec;95:15-25. Epub 2018 Oct 23 doi: 10.1016/j.jaut.2018.10.008. PMID: 30366655
Gordon FD
Surg Clin North Am 2008 Dec;88(6):1385-407, x. doi: 10.1016/j.suc.2008.07.010. PMID: 18992601
Mack CL, Sokol RJ
Pediatr Res 2005 May;57(5 Pt 2):87R-94R. Epub 2005 Apr 6 doi: 10.1203/01.PDR.0000159569.57354.47. PMID: 15817506
Wiesner RH, Ludwig J, LaRusso NF, MacCarty RL
Semin Liver Dis 1985 Aug;5(3):241-53. doi: 10.1055/s-2008-1040621. PMID: 3901273

Therapy

Cacabelos R, Naidoo V, Martínez-Iglesias O, Corzo L, Cacabelos N, Pego R, Carril JC
Methods Mol Biol 2022;2547:275-387. doi: 10.1007/978-1-0716-2573-6_13. PMID: 36068470
Silva J, Brito BS, Silva INN, Nóbrega VG, da Silva MCSM, Gomes HDN, Fortes FM, Pimentel AM, Mota J, Almeida N, Surlo VC, Lyra A, Rocha R, Santana GO
Biomed Res Int 2019;2019:7604939. Epub 2019 Jan 31 doi: 10.1155/2019/7604939. PMID: 30834274Free PMC Article
Terziroli Beretta-Piccoli B, Vergani D, Mieli-Vergani G
J Autoimmun 2018 Dec;95:15-25. Epub 2018 Oct 23 doi: 10.1016/j.jaut.2018.10.008. PMID: 30366655
Leveille-Webster C
Semin Vet Med Surg Small Anim 1997 Feb;12(1):2-9. PMID: 9057484
Wiesner RH, Ludwig J, LaRusso NF, MacCarty RL
Semin Liver Dis 1985 Aug;5(3):241-53. doi: 10.1055/s-2008-1040621. PMID: 3901273

Prognosis

Nekaeva ES, Bolshakova AE, Malysheva ES, Galova EA, Makarova EV, Nekrasova TA, Polyakova IV, Bedretdinova ZS, Belikina DV, Lavrenyuk AA, Fomin IV
Sovrem Tekhnologii Med 2021;13(4):16-24. Epub 2021 Aug 28 doi: 10.17691/stm2021.13.4.02. PMID: 34603760Free PMC Article
Alvarenga LR, Sandy NS, Gomez GS, Hessel G, DE Tommaso AMA, Bellomo-Brandão MÂ
Arq Gastroenterol 2021 Apr-Jun;58(2):227-233. doi: 10.1590/S0004-2803.202100000-41. PMID: 34287532
Weismüller TJ, Trivedi PJ, Bergquist A, Imam M, Lenzen H, Ponsioen CY, Holm K, Gotthardt D, Färkkilä MA, Marschall HU, Thorburn D, Weersma RK, Fevery J, Mueller T, Chazouillères O, Schulze K, Lazaridis KN, Almer S, Pereira SP, Levy C, Mason A, Naess S, Bowlus CL, Floreani A, Halilbasic E, Yimam KK, Milkiewicz P, Beuers U, Huynh DK, Pares A, Manser CN, Dalekos GN, Eksteen B, Invernizzi P, Berg CP, Kirchner GI, Sarrazin C, Zimmer V, Fabris L, Braun F, Marzioni M, Juran BD, Said K, Rupp C, Jokelainen K, Benito de Valle M, Saffioti F, Cheung A, Trauner M, Schramm C, Chapman RW, Karlsen TH, Schrumpf E, Strassburg CP, Manns MP, Lindor KD, Hirschfield GM, Hansen BE, Boberg KM; International PSC Study Group
Gastroenterology 2017 Jun;152(8):1975-1984.e8. Epub 2017 Mar 6 doi: 10.1053/j.gastro.2017.02.038. PMID: 28274849Free PMC Article
Tabibian JH, Enders F, Imam MH, Kolar G, Lindor KD, Talwalkar JA
Ann Hepatol 2014 May-Jun;13(3):384-9. PMID: 24756015Free PMC Article
Mohammad Alizadeh AH, Afzali ES, Mousavi M, Moaddab Y, Zali MR
Hepatobiliary Pancreat Dis Int 2010 Aug;9(4):428-32. PMID: 20688609

Clinical prediction guides

Karakas HD, Kuloglu Z, Aydin F, Ozdemir S, Avar-Aydin PO, Tuna Kirsaclioglu C, Cakar N, Ozcakar ZB
J Clin Rheumatol 2023 Dec 1;29(8):375-380. Epub 2023 Sep 19 doi: 10.1097/RHU.0000000000002027. PMID: 37723615
Silva J, Brito BS, Silva INN, Nóbrega VG, da Silva MCSM, Gomes HDN, Fortes FM, Pimentel AM, Mota J, Almeida N, Surlo VC, Lyra A, Rocha R, Santana GO
Biomed Res Int 2019;2019:7604939. Epub 2019 Jan 31 doi: 10.1155/2019/7604939. PMID: 30834274Free PMC Article
Tabibian JH, Enders F, Imam MH, Kolar G, Lindor KD, Talwalkar JA
Ann Hepatol 2014 May-Jun;13(3):384-9. PMID: 24756015Free PMC Article
Mohammad Alizadeh AH, Afzali ES, Mousavi M, Moaddab Y, Zali MR
Hepatobiliary Pancreat Dis Int 2010 Aug;9(4):428-32. PMID: 20688609
Larusso NF
P R Health Sci J 1999 Mar;18(1):11-7. PMID: 10343981

Recent systematic reviews

Onoyama T, Takeda Y, Yamashita T, Hamamoto W, Sakamoto Y, Koda H, Kawata S, Matsumoto K, Isomoto H
World J Gastroenterol 2020 Jan 21;26(3):353-365. doi: 10.3748/wjg.v26.i3.353. PMID: 31988594Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...