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Non-neoplastic nevus

MedGen UID:
78119
•Concept ID:
C0265027
•
Disease or Syndrome
Synonyms: Non-Neoplastic Nevus; non-neoplastic nevus
SNOMED CT: Non-neoplastic nevus (195381005)
 
Monarch Initiative: MONDO:0022749

Definition

A abnormal, congenital formation or mark on the skin or neighboring mucosa that does not show neoplastic growth. [from NCI]

Recent clinical studies

Etiology

Skin Lesions in Children: Evaluation of Clinicopathological Findings.
Calim-Gurbuz B, Pehlivanoglu B, Soylemez-Akkurt T, Erdem O, Ahmedov A
Turk Patoloji Derg 2023;39(3):192-198. doi: 10.5146/tjpath.2023.01599. PMID: 36779578Free PMC Article
Contiguous squamous proliferations in syringocystadenoma papilliferum: A retrospective study of 14 cases.
Aggarwal D, Chatterjee D, Keshavamurthy V, Chhikara K, Saikia UN, Radotra BD, De D, Singh MP
Indian J Dermatol Venereol Leprol 2023 Jan-Mar;89(2):266-273. doi: 10.25259/IJDVL_845_20. PMID: 34623039
Nuclear morphometric analysis in tissue as an objective tool with potential use to improve melanoma staging.
Nunes TWN, Filippi-Chiela EC, Callegari-Jacques SM, da Silva VD, Sansonowicz T, Lenz G, Roehe AV
Melanoma Res 2019 Oct;29(5):474-482. doi: 10.1097/CMR.0000000000000594. PMID: 30839356
Melanocytic nevi and non-neoplastic hyperpigmentations.
Clemente C
Pathologica 2017 Jun;109(2):67-96. PMID: 28748967
Lessons from the skin--cutaneous features of familial cancer.
Winship IM, Dudding TE
Lancet Oncol 2008 May;9(5):462-72. doi: 10.1016/S1470-2045(08)70126-8. PMID: 18452857

Diagnosis

Skin Lesions in Children: Evaluation of Clinicopathological Findings.
Calim-Gurbuz B, Pehlivanoglu B, Soylemez-Akkurt T, Erdem O, Ahmedov A
Turk Patoloji Derg 2023;39(3):192-198. doi: 10.5146/tjpath.2023.01599. PMID: 36779578Free PMC Article
A UHPLC-Mass Spectrometry View of Human Melanocytic Cells Uncovers Potential Lipid Biomarkers of Melanoma.
Perez-Valle A, Abad-García B, Fresnedo O, Barreda-Gómez G, Aspichueta P, Asumendi A, Astigarraga E, Fernández JA, Boyano MD, Ochoa B
Int J Mol Sci 2021 Nov 8;22(21) doi: 10.3390/ijms222112061. PMID: 34769491Free PMC Article
Melanocytic nevi and non-neoplastic hyperpigmentations.
Clemente C
Pathologica 2017 Jun;109(2):67-96. PMID: 28748967
Benign Tumors and Tumor-like Lesions of the Vulva.
Heller DS
Clin Obstet Gynecol 2015 Sep;58(3):526-35. doi: 10.1097/GRF.0000000000000133. PMID: 26125957
SOX10 expression in malignant melanoma, carcinoma, and normal tissues.
Mohamed A, Gonzalez RS, Lawson D, Wang J, Cohen C
Appl Immunohistochem Mol Morphol 2013 Dec;21(6):506-10. doi: 10.1097/PAI.0b013e318279bc0a. PMID: 23197006

Therapy

Photodynamic therapy for dermatologic conditions in the pediatric population: a literature review.
Kumar N, Warren CB
Photodermatol Photoimmunol Photomed 2017 May;33(3):125-134. Epub 2017 Mar 17 doi: 10.1111/phpp.12296. PMID: 28130791
Independent diagnostic value of fluorescein angiography in the evaluation of intraocular tumors.
Meyer K, Augsburger JJ
Graefes Arch Clin Exp Ophthalmol 1999 Jun;237(6):489-94. doi: 10.1007/s004170050267. PMID: 10379610

Prognosis

A UHPLC-Mass Spectrometry View of Human Melanocytic Cells Uncovers Potential Lipid Biomarkers of Melanoma.
Perez-Valle A, Abad-García B, Fresnedo O, Barreda-Gómez G, Aspichueta P, Asumendi A, Astigarraga E, Fernández JA, Boyano MD, Ochoa B
Int J Mol Sci 2021 Nov 8;22(21) doi: 10.3390/ijms222112061. PMID: 34769491Free PMC Article
Nuclear morphometric analysis in tissue as an objective tool with potential use to improve melanoma staging.
Nunes TWN, Filippi-Chiela EC, Callegari-Jacques SM, da Silva VD, Sansonowicz T, Lenz G, Roehe AV
Melanoma Res 2019 Oct;29(5):474-482. doi: 10.1097/CMR.0000000000000594. PMID: 30839356
Melanocytic nevi and non-neoplastic hyperpigmentations.
Clemente C
Pathologica 2017 Jun;109(2):67-96. PMID: 28748967
SOX10 expression in malignant melanoma, carcinoma, and normal tissues.
Mohamed A, Gonzalez RS, Lawson D, Wang J, Cohen C
Appl Immunohistochem Mol Morphol 2013 Dec;21(6):506-10. doi: 10.1097/PAI.0b013e318279bc0a. PMID: 23197006
Independent diagnostic value of fluorescein angiography in the evaluation of intraocular tumors.
Meyer K, Augsburger JJ
Graefes Arch Clin Exp Ophthalmol 1999 Jun;237(6):489-94. doi: 10.1007/s004170050267. PMID: 10379610

Clinical prediction guides

Nuclear morphometric analysis in tissue as an objective tool with potential use to improve melanoma staging.
Nunes TWN, Filippi-Chiela EC, Callegari-Jacques SM, da Silva VD, Sansonowicz T, Lenz G, Roehe AV
Melanoma Res 2019 Oct;29(5):474-482. doi: 10.1097/CMR.0000000000000594. PMID: 30839356
SOX10 expression in malignant melanoma, carcinoma, and normal tissues.
Mohamed A, Gonzalez RS, Lawson D, Wang J, Cohen C
Appl Immunohistochem Mol Morphol 2013 Dec;21(6):506-10. doi: 10.1097/PAI.0b013e318279bc0a. PMID: 23197006
Clusterin expression in primary and metastatic melanoma.
Busam KJ, Kucukgol D, Eastlake-Wade S, Frosina D, Delgado R, Jungbluth AA
J Cutan Pathol 2006 Sep;33(9):619-23. doi: 10.1111/j.1600-0560.2006.00481.x. PMID: 16965336
Independent diagnostic value of fluorescein angiography in the evaluation of intraocular tumors.
Meyer K, Augsburger JJ
Graefes Arch Clin Exp Ophthalmol 1999 Jun;237(6):489-94. doi: 10.1007/s004170050267. PMID: 10379610
Detection of proopiomelanocortin-derived antigens in normal and pathologic human skin.
Slominski A, Wortsman J, Mazurkiewicz JE, Matsuoka L, Dietrich J, Lawrence K, Gorbani A, Paus R
J Lab Clin Med 1993 Dec;122(6):658-66. PMID: 8245685

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