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Metastatic Adult Soft Tissue Sarcoma

MedGen UID:
78857
•Concept ID:
C0278664
•
Neoplastic Process

Definition

A sarcoma that arises from the soft tissues during adulthood and has spread from the original site of growth to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Adult Soft Tissue Sarcoma

Professional guidelines

PubMed

Dose-intensive chemotherapy with growth factor or autologous bone marrow/stem cell transplant support in first-line treatment of advanced or metastatic adult soft tissue sarcoma: a systematic review.
Verma S, Younus J, Stys-Norman D, Haynes AE, Blackstein M; Sarcoma Disease Site Group of Cancer Care Ontario's Program in Evidence-based Care
Cancer 2008 Mar 15;112(6):1197-205. doi: 10.1002/cncr.23302. PMID: 18224666
Systemic treatment options for patients with refractory adult-type sarcoma beyond anthracyclines.
Hartmann JT
Anticancer Drugs 2007 Mar;18(3):245-54. doi: 10.1097/CAD.0b013e3280124e41. PMID: 17264755

Recent clinical studies

Etiology

Dose-intensive chemotherapy with growth factor or autologous bone marrow/stem cell transplant support in first-line treatment of advanced or metastatic adult soft tissue sarcoma: a systematic review.
Verma S, Younus J, Stys-Norman D, Haynes AE, Blackstein M; Sarcoma Disease Site Group of Cancer Care Ontario's Program in Evidence-based Care
Cancer 2008 Mar 15;112(6):1197-205. doi: 10.1002/cncr.23302. PMID: 18224666

Diagnosis

Systemic treatment options for patients with refractory adult-type sarcoma beyond anthracyclines.
Hartmann JT
Anticancer Drugs 2007 Mar;18(3):245-54. doi: 10.1097/CAD.0b013e3280124e41. PMID: 17264755
Recent developments in salvage chemotherapy for patients with metastatic soft tissue sarcoma.
Hartmann JT, Patel S
Drugs 2005;65(2):167-78. doi: 10.2165/00003495-200565020-00002. PMID: 15631540

Therapy

Dose-intensive chemotherapy with growth factor or autologous bone marrow/stem cell transplant support in first-line treatment of advanced or metastatic adult soft tissue sarcoma: a systematic review.
Verma S, Younus J, Stys-Norman D, Haynes AE, Blackstein M; Sarcoma Disease Site Group of Cancer Care Ontario's Program in Evidence-based Care
Cancer 2008 Mar 15;112(6):1197-205. doi: 10.1002/cncr.23302. PMID: 18224666
Systemic treatment options for patients with refractory adult-type sarcoma beyond anthracyclines.
Hartmann JT
Anticancer Drugs 2007 Mar;18(3):245-54. doi: 10.1097/CAD.0b013e3280124e41. PMID: 17264755
Recent developments in salvage chemotherapy for patients with metastatic soft tissue sarcoma.
Hartmann JT, Patel S
Drugs 2005;65(2):167-78. doi: 10.2165/00003495-200565020-00002. PMID: 15631540
Combination of 5-fluorouracil, adriamycin, ifosfamide and cisplatin in metastatic adult soft tissue sarcoma: results of a phase II study.
Jäger E, Klein O, Wächter B, Bernhard H, Dippold W, Meyer zum Büschenfelde KH, Knuth A
Oncology 1996 Jan-Feb;53(1):58-63. doi: 10.1159/000227536. PMID: 8570133

Clinical prediction guides

Dose-intensive chemotherapy with growth factor or autologous bone marrow/stem cell transplant support in first-line treatment of advanced or metastatic adult soft tissue sarcoma: a systematic review.
Verma S, Younus J, Stys-Norman D, Haynes AE, Blackstein M; Sarcoma Disease Site Group of Cancer Care Ontario's Program in Evidence-based Care
Cancer 2008 Mar 15;112(6):1197-205. doi: 10.1002/cncr.23302. PMID: 18224666
Combination of 5-fluorouracil, adriamycin, ifosfamide and cisplatin in metastatic adult soft tissue sarcoma: results of a phase II study.
Jäger E, Klein O, Wächter B, Bernhard H, Dippold W, Meyer zum Büschenfelde KH, Knuth A
Oncology 1996 Jan-Feb;53(1):58-63. doi: 10.1159/000227536. PMID: 8570133

Recent systematic reviews

Dose-intensive chemotherapy with growth factor or autologous bone marrow/stem cell transplant support in first-line treatment of advanced or metastatic adult soft tissue sarcoma: a systematic review.
Verma S, Younus J, Stys-Norman D, Haynes AE, Blackstein M; Sarcoma Disease Site Group of Cancer Care Ontario's Program in Evidence-based Care
Cancer 2008 Mar 15;112(6):1197-205. doi: 10.1002/cncr.23302. PMID: 18224666

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