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Localized Parathyroid Gland Carcinoma

MedGen UID:
82959
•Concept ID:
C0278680
•
Neoplastic Process
Synonyms: Localized Parathyroid Cancer; Localized Parathyroid Carcinoma

Definition

A parathyroid gland carcinoma that has not spread to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocalized Parathyroid Gland Carcinoma

Professional guidelines

PubMed

Editorial: Parathyroid atypical adenomas and carcinoma: An update on clinical management.
Gianotti L, Cetani F
Front Endocrinol (Lausanne) 2023;14:1163996. Epub 2023 Feb 24 doi: 10.3389/fendo.2023.1163996. PMID: 36909324Free PMC Article
Contemporary Evaluation and Management of Parathyroid Carcinoma.
Fingeret AL
JCO Oncol Pract 2021 Jan;17(1):17-21. Epub 2020 Feb 10 doi: 10.1200/JOP.19.00540. PMID: 32040373
Management of thyroid cancer: United Kingdom National Multidisciplinary Guidelines.
Mitchell AL, Gandhi A, Scott-Coombes D, Perros P
J Laryngol Otol 2016 May;130(S2):S150-S160. doi: 10.1017/S0022215116000578. PMID: 27841128Free PMC Article

Recent clinical studies

Etiology

Parathyroid fine-needle aspiration with parathyroid hormone washout as a preoperative localisation of parathyroid adenoma-A retrospective study.
Klein P, Alsleibi S, Cohen O, Ilany J, Hemi R, Barhod E, Vered I, Winder O, Avior G, Tripto-Shklonik L
Clin Endocrinol (Oxf) 2023 Sep;99(3):246-252. Epub 2023 Jun 7 doi: 10.1111/cen.14939. PMID: 37287384
Surgery for primary hyperparathyroidism.
das Neves MC, Santos RO, Ohe MN
Arch Endocrinol Metab 2022 Nov 11;66(5):678-688. doi: 10.20945/2359-3997000000557. PMID: 36382757Free PMC Article
Parathyroid carcinoma: update and guidelines for management.
Wei CH, Harari A
Curr Treat Options Oncol 2012 Mar;13(1):11-23. doi: 10.1007/s11864-011-0171-3. PMID: 22327883
Parathyroid carcinoma: etiology, diagnosis, and treatment.
Okamoto T, Iihara M, Obara T, Tsukada T
World J Surg 2009 Nov;33(11):2343-54. doi: 10.1007/s00268-009-9999-0. PMID: 19350316
Minimally invasive parathyroidectomy.
Sosa JA, Udelsman R
Surg Oncol 2003 Aug;12(2):125-34. doi: 10.1016/s0960-7404(03)00041-0. PMID: 12946483

Diagnosis

Parathyroid Imaging.
Lalonde MN, Correia RD, Syktiotis GP, Schaefer N, Matter M, Prior JO
Semin Nucl Med 2023 Jul;53(4):490-502. Epub 2023 Mar 14 doi: 10.1053/j.semnuclmed.2023.02.004. PMID: 36922339
Parathyroid Imaging.
Itani M, Middleton WD
Radiol Clin North Am 2020 Nov;58(6):1071-1083. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.006. PMID: 33040849
Parathyroid Carcinoma.
Cetani F, Pardi E, Marcocci C
Front Horm Res 2019;51:63-76. Epub 2018 Nov 19 doi: 10.1159/000491039. PMID: 30641523
Parathyroid carcinoma.
Givi B, Shah JP
Clin Oncol (R Coll Radiol) 2010 Aug;22(6):498-507. Epub 2010 May 26 doi: 10.1016/j.clon.2010.04.007. PMID: 20510594Free PMC Article
Parathyroid imaging.
Fakhran S, Branstetter BF 4th, Pryma DA
Neuroimaging Clin N Am 2008 Aug;18(3):537-49, ix. doi: 10.1016/j.nic.2008.03.006. PMID: 18656034

Therapy

Surgery for primary hyperparathyroidism.
das Neves MC, Santos RO, Ohe MN
Arch Endocrinol Metab 2022 Nov 11;66(5):678-688. doi: 10.20945/2359-3997000000557. PMID: 36382757Free PMC Article
Surgical Aspects of Primary Hyperparathyroidism.
Perrier N, Lang BH, Farias LCB, Poch LL, Sywak M, Almquist M, Vriens MR, Yeh MW, Shariq O, Duh QY, Yeh R, Vu T, LiVolsi V, Sitges-Serra A
J Bone Miner Res 2022 Nov;37(11):2373-2390. Epub 2022 Oct 17 doi: 10.1002/jbmr.4689. PMID: 36054175
Targeted therapy and drug resistance in thyroid cancer.
Zhang Y, Xing Z, Liu T, Tang M, Mi L, Zhu J, Wu W, Wei T
Eur J Med Chem 2022 Aug 5;238:114500. Epub 2022 May 29 doi: 10.1016/j.ejmech.2022.114500. PMID: 35675754
Primary hyperparathyroidism during pregnancy.
Dochez V, Ducarme G
Arch Gynecol Obstet 2015 Feb;291(2):259-63. Epub 2014 Nov 4 doi: 10.1007/s00404-014-3526-8. PMID: 25367603
Parathyroid carcinoma.
Kebebew E
Curr Treat Options Oncol 2001 Aug;2(4):347-54. doi: 10.1007/s11864-001-0028-2. PMID: 12057115

Prognosis

Parathyroid carcinoma: molecular therapeutic targets.
Marini F, Giusti F, Palmini G, Aurilia C, Donati S, Brandi ML
Endocrine 2023 Sep;81(3):409-418. Epub 2023 May 9 doi: 10.1007/s12020-023-03376-w. PMID: 37160841
Parathyroid Imaging.
Itani M, Middleton WD
Radiol Clin North Am 2020 Nov;58(6):1071-1083. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.006. PMID: 33040849
Parathyroid cancer: An update.
Rodrigo JP, Hernandez-Prera JC, Randolph GW, Zafereo ME, Hartl DM, Silver CE, Suárez C, Owen RP, Bradford CR, Mäkitie AA, Shaha AR, Bishop JA, Rinaldo A, Ferlito A
Cancer Treat Rev 2020 Jun;86:102012. Epub 2020 Mar 19 doi: 10.1016/j.ctrv.2020.102012. PMID: 32247225
Parathyroid carcinoma.
Givi B, Shah JP
Clin Oncol (R Coll Radiol) 2010 Aug;22(6):498-507. Epub 2010 May 26 doi: 10.1016/j.clon.2010.04.007. PMID: 20510594Free PMC Article
Parathyroid carcinoma.
Kebebew E
Curr Treat Options Oncol 2001 Aug;2(4):347-54. doi: 10.1007/s11864-001-0028-2. PMID: 12057115

Clinical prediction guides

Clinical predictors of ectopic parathyroid adenomas: experience with 421 confirmed parathyroid adenoma localizations.
Durmuş ET, Atmaca A, Kefeli M, Çolak R, Durmuş B, Polat C
J Endocrinol Invest 2023 Jun;46(6):1197-1203. Epub 2022 Dec 12 doi: 10.1007/s40618-022-01986-1. PMID: 36510103
Surgical Aspects of Primary Hyperparathyroidism.
Perrier N, Lang BH, Farias LCB, Poch LL, Sywak M, Almquist M, Vriens MR, Yeh MW, Shariq O, Duh QY, Yeh R, Vu T, LiVolsi V, Sitges-Serra A
J Bone Miner Res 2022 Nov;37(11):2373-2390. Epub 2022 Oct 17 doi: 10.1002/jbmr.4689. PMID: 36054175
Update on parathyroid carcinoma.
Cetani F, Pardi E, Marcocci C
J Endocrinol Invest 2016 Jun;39(6):595-606. Epub 2016 Mar 21 doi: 10.1007/s40618-016-0447-3. PMID: 27001435
Parathyroid Carcinoma: Diagnosis and Clinical Implications.
Duan K, Mete Ö
Turk Patoloji Derg 2015;31 Suppl 1:80-97. doi: 10.5146/tjpath.2015.01316. PMID: 26177319
Sestamibi parathyroid imaging.
McBiles M, Lambert AT, Cote MG, Kim SY
Semin Nucl Med 1995 Jul;25(3):221-34. doi: 10.1016/s0001-2998(95)80012-3. PMID: 7570042

Recent systematic reviews

Parathyroid Cystic Adenoma: A Systematic Review and Meta-Analysis.
Daoud A, Ronen O
Endocr Pract 2023 Jan;29(1):2-10. Epub 2022 Nov 10 doi: 10.1016/j.eprac.2022.11.004. PMID: 36370985
Hürthle Cell Carcinoma of the Thyroid Gland: Systematic Review and Meta-analysis.
Coca-Pelaz A, Rodrigo JP, Shah JP, Sanabria A, Al Ghuzlan A, Silver CE, Shaha AR, Angelos P, Hartl DM, Mäkitie AA, Olsen KD, Owen RP, Randolph GW, Simó R, Tufano RP, Kowalski LP, Zafereo ME, Rinaldo A, Ferlito A
Adv Ther 2021 Oct;38(10):5144-5164. Epub 2021 Aug 22 doi: 10.1007/s12325-021-01876-7. PMID: 34423400
Parathyroid cancer: A systematic review of diagnostic biomarkers.
Davies MP, John Evans TW, Tahir F, Balasubramanian SP
Surgeon 2021 Dec;19(6):e536-e548. Epub 2021 Feb 26 doi: 10.1016/j.surge.2021.01.011. PMID: 33642204
Diagnostic performance of computed tomography for parathyroid adenoma localization; a systematic review and meta-analysis.
Kluijfhout WP, Pasternak JD, Beninato T, Drake FT, Gosnell JE, Shen WT, Duh QY, Allen IE, Vriens MR, de Keizer B, Hope TA, Suh I
Eur J Radiol 2017 Mar;88:117-128. Epub 2017 Jan 5 doi: 10.1016/j.ejrad.2017.01.004. PMID: 28189196
Parathyroid imaging: how good is it and how should it be done?
Kettle AG, O'Doherty MJ
Semin Nucl Med 2006 Jul;36(3):206-11. doi: 10.1053/j.semnuclmed.2006.03.003. PMID: 16762611

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