U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Atrophy

MedGen UID:
83084
Concept ID:
C0333641
Pathologic Function
Synonym: Atrophies
SNOMED CT: Atrophic (13331008); Atrophy (13331008)

Definition

Any weakening or degeneration, especially through lack of use. [from NCI]

Professional guidelines

PubMed

Bennett JL, Costello F, Chen JJ, Petzold A, Biousse V, Newman NJ, Galetta SL
Lancet Neurol 2023 Jan;22(1):89-100. Epub 2022 Sep 22 doi: 10.1016/S1474-4422(22)00187-9. PMID: 36155661
Shah SC, Piazuelo MB, Kuipers EJ, Li D
Gastroenterology 2021 Oct;161(4):1325-1332.e7. Epub 2021 Aug 26 doi: 10.1053/j.gastro.2021.06.078. PMID: 34454714Free PMC Article
Castelli G, Desai KM, Cantone RE
Am Fam Physician 2020 Dec 15;102(12):732-739. PMID: 33320513

Recent clinical studies

Etiology

Blair HA
CNS Drugs 2022 Sep;36(9):995-1005. Epub 2022 Aug 12 doi: 10.1007/s40263-022-00941-1. PMID: 35960489
Paik J
CNS Drugs 2022 Apr;36(4):401-410. Epub 2022 Mar 13 doi: 10.1007/s40263-022-00910-8. PMID: 35284988
Finkel RS, Mercuri E, Meyer OH, Simonds AK, Schroth MK, Graham RJ, Kirschner J, Iannaccone ST, Crawford TO, Woods S, Muntoni F, Wirth B, Montes J, Main M, Mazzone ES, Vitale M, Snyder B, Quijano-Roy S, Bertini E, Davis RH, Qian Y, Sejersen T; SMA Care group
Neuromuscul Disord 2018 Mar;28(3):197-207. Epub 2017 Nov 23 doi: 10.1016/j.nmd.2017.11.004. PMID: 29305137
Chiriboga CA
Expert Rev Neurother 2017 Oct;17(10):955-962. Epub 2017 Sep 8 doi: 10.1080/14737175.2017.1364159. PMID: 28884620
Arnold WD, Kassar D, Kissel JT
Muscle Nerve 2015 Feb;51(2):157-67. Epub 2014 Dec 16 doi: 10.1002/mus.24497. PMID: 25346245Free PMC Article

Diagnosis

Leńska-Mieciek M, Madetko-Alster N, Alster P, Królicki L, Fiszer U, Koziorowski D
Front Immunol 2023;14:1214677. Epub 2023 Jun 22 doi: 10.3389/fimmu.2023.1214677. PMID: 37426656Free PMC Article
Goh YY, Saunders E, Pavey S, Rushton E, Quinn N, Houlden H, Chelban V
Pract Neurol 2023 Jun;23(3):208-221. Epub 2023 Mar 16 doi: 10.1136/pn-2020-002797. PMID: 36927875Free PMC Article
Mercuri E, Sumner CJ, Muntoni F, Darras BT, Finkel RS
Nat Rev Dis Primers 2022 Aug 4;8(1):52. doi: 10.1038/s41572-022-00380-8. PMID: 35927425
Nicolau S, Waldrop MA, Connolly AM, Mendell JR
Semin Pediatr Neurol 2021 Apr;37:100878. Epub 2021 Feb 11 doi: 10.1016/j.spen.2021.100878. PMID: 33892848
Fanciulli A, Stankovic I, Krismer F, Seppi K, Levin J, Wenning GK
Int Rev Neurobiol 2019;149:137-192. Epub 2019 Nov 21 doi: 10.1016/bs.irn.2019.10.004. PMID: 31779811

Therapy

Day JW, Howell K, Place A, Long K, Rossello J, Kertesz N, Nomikos G
BMC Pediatr 2022 Nov 3;22(1):632. doi: 10.1186/s12887-022-03671-x. PMID: 36329412Free PMC Article
Ammar MJ, Hsu J, Chiang A, Ho AC, Regillo CD
Curr Opin Ophthalmol 2020 May;31(3):215-221. doi: 10.1097/ICU.0000000000000657. PMID: 32205470
Lipker LA, Persinger CR, Michalko BS, Durall CJ
J Sport Rehabil 2019 Nov 1;28(8):897-901. doi: 10.1123/jsr.2018-0062. PMID: 30300054
Monje A, Chan HL, Galindo-Moreno P, Elnayef B, Suarez-Lopez del Amo F, Wang F, Wang HL
J Periodontol 2015 Nov;86(11):1231-48. Epub 2015 Jul 16 doi: 10.1902/jop.2015.150263. PMID: 26177631
Brumann M, Baumbach SF, Mutschler W, Polzer H
Injury 2014 Nov;45(11):1782-90. Epub 2014 Jul 7 doi: 10.1016/j.injury.2014.06.022. PMID: 25059505

Prognosis

Erdos J, Wild C
Eur J Paediatr Neurol 2022 Jul;39:1-10. Epub 2022 Apr 30 doi: 10.1016/j.ejpn.2022.04.006. PMID: 35533607
Goligher EC, Dres M, Fan E, Rubenfeld GD, Scales DC, Herridge MS, Vorona S, Sklar MC, Rittayamai N, Lanys A, Murray A, Brace D, Urrea C, Reid WD, Tomlinson G, Slutsky AS, Kavanagh BP, Brochard LJ, Ferguson ND
Am J Respir Crit Care Med 2018 Jan 15;197(2):204-213. doi: 10.1164/rccm.201703-0536OC. PMID: 28930478
Verhaart IEC, Robertson A, Wilson IJ, Aartsma-Rus A, Cameron S, Jones CC, Cook SF, Lochmüller H
Orphanet J Rare Dis 2017 Jul 4;12(1):124. doi: 10.1186/s13023-017-0671-8. PMID: 28676062Free PMC Article
Hermans G, Van den Berghe G
Crit Care 2015 Aug 5;19(1):274. doi: 10.1186/s13054-015-0993-7. PMID: 26242743Free PMC Article
Malamut G, Cellier C
Expert Rev Gastroenterol Hepatol 2014 Mar;8(3):323-8. Epub 2014 Feb 6 doi: 10.1586/17474124.2014.887438. PMID: 24502536

Clinical prediction guides

Indiran V, Jagannathan K
Abdom Radiol (NY) 2017 Nov;42(11):2780. doi: 10.1007/s00261-017-1199-z. PMID: 28555264
Elli L, Branchi F, Sidhu R, Guandalini S, Assiri A, Rinawi F, Shamir R, Das P, Makharia GK
Expert Rev Gastroenterol Hepatol 2017 Feb;11(2):125-138. Epub 2016 Dec 29 doi: 10.1080/17474124.2017.1274231. PMID: 28000520
Kono S, Gotoda T, Yoshida S, Oda I, Kondo H, Gatta L, Naylor G, Dixon M, Moriyasu F, Axon A
World J Gastroenterol 2015 Dec 14;21(46):13113-23. doi: 10.3748/wjg.v21.i46.13113. PMID: 26673849Free PMC Article
Ohno-Matsui K, Kawasaki R, Jonas JB, Cheung CM, Saw SM, Verhoeven VJ, Klaver CC, Moriyama M, Shinohara K, Kawasaki Y, Yamazaki M, Meuer S, Ishibashi T, Yasuda M, Yamashita H, Sugano A, Wang JJ, Mitchell P, Wong TY; META-analysis for Pathologic Myopia (META-PM) Study Group
Am J Ophthalmol 2015 May;159(5):877-83.e7. Epub 2015 Jan 26 doi: 10.1016/j.ajo.2015.01.022. PMID: 25634530
Genta RM
Aliment Pharmacol Ther 1998 Feb;12 Suppl 1:17-23. doi: 10.1111/j.1365-2036.1998.00003.x. PMID: 9701001

Recent systematic reviews

Fazzini B, Märkl T, Costas C, Blobner M, Schaller SJ, Prowle J, Puthucheary Z, Wackerhage H
Crit Care 2023 Jan 3;27(1):2. doi: 10.1186/s13054-022-04253-0. PMID: 36597123Free PMC Article
Wenning GK, Stankovic I, Vignatelli L, Fanciulli A, Calandra-Buonaura G, Seppi K, Palma JA, Meissner WG, Krismer F, Berg D, Cortelli P, Freeman R, Halliday G, Höglinger G, Lang A, Ling H, Litvan I, Low P, Miki Y, Panicker J, Pellecchia MT, Quinn N, Sakakibara R, Stamelou M, Tolosa E, Tsuji S, Warner T, Poewe W, Kaufmann H
Mov Disord 2022 Jun;37(6):1131-1148. Epub 2022 Apr 21 doi: 10.1002/mds.29005. PMID: 35445419Free PMC Article
Kreider RB, Stout JR
Nutrients 2021 Jan 29;13(2) doi: 10.3390/nu13020447. PMID: 33572884Free PMC Article
Goubert D, Oosterwijck JV, Meeus M, Danneels L
Pain Physician 2016 Sep-Oct;19(7):E985-E1000. PMID: 27676689
Gheorghe A, Mahdi L, Musat O
Rom J Ophthalmol 2015 Apr-Jun;59(2):74-7. PMID: 26978865Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...