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Stromal hyperplasia

MedGen UID:
83100
•Concept ID:
C0334002
•
Pathologic Function
Synonym: Stromal Hyperplasia
SNOMED CT: Stromal hyperplasia (75235002)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStromal hyperplasia

Professional guidelines

PubMed

Management of Gynecomastia and Male Benign Diseases.
Karamchandani MM, De La Cruz Ku G, Sokol BL, Chatterjee A, Homsy C
Surg Clin North Am 2022 Dec;102(6):989-1005. doi: 10.1016/j.suc.2022.06.003. PMID: 36335933
Differential Diagnosis of Benign Spindle Cell Lesions.
Magro G
Surg Pathol Clin 2018 Mar;11(1):91-121. Epub 2017 Dec 9 doi: 10.1016/j.path.2017.09.005. PMID: 29413661
Diagnosis and management of benign, atypical, and indeterminate breast lesions detected on core needle biopsy.
Neal L, Sandhu NP, Hieken TJ, Glazebrook KN, Mac Bride MB, Dilaveri CA, Wahner-Roedler DL, Ghosh K, Visscher DW
Mayo Clin Proc 2014 Apr;89(4):536-47. doi: 10.1016/j.mayocp.2014.02.004. PMID: 24684875

Recent clinical studies

Etiology

Pseudoangiomatous stromal hyperplasia of the breast: Clinical evaluation.
Esmer AC, Tazeoglu D, Dag A
Breast Dis 2023;42(1):115-119. doi: 10.3233/BD-220070. PMID: 37066901
Keep CALME (childhood asymmetry labium majus enlargement) and follow up.
Sechi A, Patrizi A, Vara G, Golfieri R, Neri I
J Dtsch Dermatol Ges 2021 Sep;19(9):1276-1281. Epub 2021 Jun 23 doi: 10.1111/ddg.14528. PMID: 34164912
Quantification of Leydig cells and stromal hyperplasia in the postmenopausal ovary of women with endometrial carcinoma.
Reijnen C, Küsters-Vandevelde HVN, Abbink K, Zusterzeel PLM, van Herwaarden AE, van der Laak JAWM, Massuger LFAG, Snijders MPLM, Pijnenborg JMA, Bulten J
Hum Pathol 2019 Mar;85:119-127. Epub 2018 Nov 11 doi: 10.1016/j.humpath.2018.10.022. PMID: 30428390
Pseudoangiomatous Stromal Hyperplasia of the Breast: Multimodality Review With Pathologic Correlation.
Raj SD, Sahani VG, Adrada BE, Scoggins ME, Albarracin CT, Woodtichartpreecha P, Posleman Monetto FE, Whitman GJ
Curr Probl Diagn Radiol 2017 Mar-Apr;46(2):130-135. Epub 2016 Feb 2 doi: 10.1067/j.cpradiol.2016.01.005. PMID: 26949063
Pseudoangiomatous stromal hyperplasia: an overview.
Virk RK, Khan A
Arch Pathol Lab Med 2010 Jul;134(7):1070-4. doi: 10.5858/2008-0686-RS.1. PMID: 20586640

Diagnosis

Management of Gynecomastia and Male Benign Diseases.
Karamchandani MM, De La Cruz Ku G, Sokol BL, Chatterjee A, Homsy C
Surg Clin North Am 2022 Dec;102(6):989-1005. doi: 10.1016/j.suc.2022.06.003. PMID: 36335933
Management of Stromal Lesions.
Yu J, Kansal K
Surg Clin North Am 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002. PMID: 36335922
Prostatic stromal proliferations: a review.
Bostwick DG, Egevad L
Pathology 2021 Jan;53(1):12-25. Epub 2020 Nov 13 doi: 10.1016/j.pathol.2020.09.017. PMID: 33190920
Mesenchymal breast lesions.
Schickman R, Leibman AJ, Handa P, Kornmehl A, Abadi M
Clin Radiol 2015 Jun;70(6):567-75. Epub 2015 Jan 29 doi: 10.1016/j.crad.2014.12.015. PMID: 25638601
Diagnosis and management of benign, atypical, and indeterminate breast lesions detected on core needle biopsy.
Neal L, Sandhu NP, Hieken TJ, Glazebrook KN, Mac Bride MB, Dilaveri CA, Wahner-Roedler DL, Ghosh K, Visscher DW
Mayo Clin Proc 2014 Apr;89(4):536-47. doi: 10.1016/j.mayocp.2014.02.004. PMID: 24684875

Therapy

A review of pediatric macromastia etiology and indications for reduction mammaplasty.
Kikuchi DS, Mustin DE, Ghanouni A, Walsh MD
J Plast Reconstr Aesthet Surg 2023 Feb;77:209-217. Epub 2022 Dec 19 doi: 10.1016/j.bjps.2022.12.003. PMID: 36587475
Management of Stromal Lesions.
Yu J, Kansal K
Surg Clin North Am 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002. PMID: 36335922
Pseudoangiomatous stromal hyperplasia of the breast.
AbdullGaffar B
Arch Pathol Lab Med 2009 Aug;133(8):1335-8. doi: 10.5858/133.8.1335. PMID: 19653734
Hormonal pathology of the endometrium.
Deligdisch L
Mod Pathol 2000 Mar;13(3):285-94. doi: 10.1038/modpathol.3880050. PMID: 10757339
Effects of hormone therapy on the endometrium.
Deligdisch L
Mod Pathol 1993 Jan;6(1):94-106. PMID: 8426860

Prognosis

Management of Stromal Lesions.
Yu J, Kansal K
Surg Clin North Am 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002. PMID: 36335922
Keep CALME (childhood asymmetry labium majus enlargement) and follow up.
Sechi A, Patrizi A, Vara G, Golfieri R, Neri I
J Dtsch Dermatol Ges 2021 Sep;19(9):1276-1281. Epub 2021 Jun 23 doi: 10.1111/ddg.14528. PMID: 34164912
Unilateral gynecomastia and pseudoangiomatous stromal hyperplasia in neurofibromatosis: case report and review of the literature.
Kimura S, Tanimoto A, Shimajiri S, Sasaguri T, Yamada S, Wang KY, Guo X, Sasaguri Y
Pathol Res Pract 2012 May 15;208(5):318-22. Epub 2012 Apr 19 doi: 10.1016/j.prp.2012.03.003. PMID: 22520406
Pseudoangiomatous stromal hyperplasia: an overview.
Virk RK, Khan A
Arch Pathol Lab Med 2010 Jul;134(7):1070-4. doi: 10.5858/2008-0686-RS.1. PMID: 20586640
Pseudoangiomatous stromal hyperplasia of the breast.
AbdullGaffar B
Arch Pathol Lab Med 2009 Aug;133(8):1335-8. doi: 10.5858/133.8.1335. PMID: 19653734

Clinical prediction guides

Pseudoangiomatous stromal hyperplasia of the breast: Clinical evaluation.
Esmer AC, Tazeoglu D, Dag A
Breast Dis 2023;42(1):115-119. doi: 10.3233/BD-220070. PMID: 37066901
Management of Stromal Lesions.
Yu J, Kansal K
Surg Clin North Am 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002. PMID: 36335922
Upstaging of Fibroepithelial Lesions: A Single-Institution Experience.
Mohan SC, Tseng J, Marumoto A, Angarita S, Dadmanesh F, Amersi F, Giuliano A, Chung A
Ann Surg Oncol 2022 Apr;29(4):2193-2199. Epub 2021 Oct 20 doi: 10.1245/s10434-021-10931-0. PMID: 34671884
Quantification of Leydig cells and stromal hyperplasia in the postmenopausal ovary of women with endometrial carcinoma.
Reijnen C, Küsters-Vandevelde HVN, Abbink K, Zusterzeel PLM, van Herwaarden AE, van der Laak JAWM, Massuger LFAG, Snijders MPLM, Pijnenborg JMA, Bulten J
Hum Pathol 2019 Mar;85:119-127. Epub 2018 Nov 11 doi: 10.1016/j.humpath.2018.10.022. PMID: 30428390
Myofibroblastic, fibroblastic and myoid lesions of the breast.
Krings G, McIntire P, Shin SJ
Semin Diagn Pathol 2017 Sep;34(5):427-437. Epub 2017 May 28 doi: 10.1053/j.semdp.2017.05.010. PMID: 28751104

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