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Stromal hyperplasia

MedGen UID:: 83100
•Concept ID:: C0334002
•: Pathologic Function

Synonym:	Stromal Hyperplasia
SNOMED CT:	Stromal hyperplasia (75235002)

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVStromal hyperplasia

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Non-Neoplastic Disorder
      - Non-Neoplastic Disorder by Special Category
        Hyperplasia
        Stromal hyperplasia
        Pseudoangiomatous stromal hyperplasia

Professional guidelines

PubMed

Management of Gynecomastia and Male Benign Diseases.

Karamchandani MM, De La Cruz Ku G, Sokol BL, Chatterjee A, Homsy C
Surg Clin North Am 2022 Dec;102(6):989-1005. doi: 10.1016/j.suc.2022.06.003. PMID: 36335933

Differential Diagnosis of Benign Spindle Cell Lesions.

Magro G
Surg Pathol Clin 2018 Mar;11(1):91-121. Epub 2017 Dec 9 doi: 10.1016/j.path.2017.09.005. PMID: 29413661

Diagnosis and management of benign, atypical, and indeterminate breast lesions detected on core needle biopsy.

Neal L, Sandhu NP, Hieken TJ, Glazebrook KN, Mac Bride MB, Dilaveri CA, Wahner-Roedler DL, Ghosh K, Visscher DW
Mayo Clin Proc 2014 Apr;89(4):536-47. doi: 10.1016/j.mayocp.2014.02.004. PMID: 24684875

See all (12)

Recent clinical studies

Etiology

Pseudoangiomatous stromal hyperplasia: A clinical perspective and a brief review.

Patel G, Bipte S, Narurkar S
J Cancer Res Ther 2023 Oct 1;19(7):1714-1720. Epub 2023 Jan 3 doi: 10.4103/jcrt.jcrt_127_22. PMID: 38376269

Pseudoangiomatous stromal hyperplasia of the breast: Clinical evaluation.

Esmer AC, Tazeoglu D, Dag A
Breast Dis 2023;42(1):115-119. doi: 10.3233/BD-220070. PMID: 37066901

Keep CALME (childhood asymmetry labium majus enlargement) and follow up.

Sechi A, Patrizi A, Vara G, Golfieri R, Neri I
J Dtsch Dermatol Ges 2021 Sep;19(9):1276-1281. Epub 2021 Jun 23 doi: 10.1111/ddg.14528. PMID: 34164912

Pseudoangiomatous Stromal Hyperplasia of the Breast: Multimodality Review With Pathologic Correlation.

Raj SD, Sahani VG, Adrada BE, Scoggins ME, Albarracin CT, Woodtichartpreecha P, Posleman Monetto FE, Whitman GJ
Curr Probl Diagn Radiol 2017 Mar-Apr;46(2):130-135. Epub 2016 Feb 2 doi: 10.1067/j.cpradiol.2016.01.005. PMID: 26949063

Pseudoangiomatous stromal hyperplasia: an overview.

Virk RK, Khan A
Arch Pathol Lab Med 2010 Jul;134(7):1070-4. doi: 10.5858/2008-0686-RS.1. PMID: 20586640

See all (95)

Diagnosis

Pseudoangiomatous stromal hyperplasia of the breast: Clinical evaluation.

Esmer AC, Tazeoglu D, Dag A
Breast Dis 2023;42(1):115-119. doi: 10.3233/BD-220070. PMID: 37066901

Management of Stromal Lesions.

Yu J, Kansal K
Surg Clin North Am 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002. PMID: 36335922

Prostatic stromal proliferations: a review.

Bostwick DG, Egevad L
Pathology 2021 Jan;53(1):12-25. Epub 2020 Nov 13 doi: 10.1016/j.pathol.2020.09.017. PMID: 33190920

Myofibroblastic, fibroblastic and myoid lesions of the breast.

Krings G, McIntire P, Shin SJ
Semin Diagn Pathol 2017 Sep;34(5):427-437. Epub 2017 May 28 doi: 10.1053/j.semdp.2017.05.010. PMID: 28751104

Mesenchymal breast lesions.

Schickman R, Leibman AJ, Handa P, Kornmehl A, Abadi M
Clin Radiol 2015 Jun;70(6):567-75. Epub 2015 Jan 29 doi: 10.1016/j.crad.2014.12.015. PMID: 25638601

See all (179)

Therapy

A review of pediatric macromastia etiology and indications for reduction mammaplasty.

Kikuchi DS, Mustin DE, Ghanouni A, Walsh MD
J Plast Reconstr Aesthet Surg 2023 Feb;77:209-217. Epub 2022 Dec 19 doi: 10.1016/j.bjps.2022.12.003. PMID: 36587475

Management of Stromal Lesions.

Yu J, Kansal K
Surg Clin North Am 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002. PMID: 36335922

Breast hamartoma: reassessment of an under-recognised breast lesion.

Alran L, Chamming's F, Auriol-Leizagoyen S, Velasco V, Deleau F, Brouste V, Bonhomme B, Ben Rejeb H, Marty M, MacGrogan G
Histopathology 2022 Jan;80(2):304-313. Epub 2021 Sep 22 doi: 10.1111/his.14544. PMID: 34403159

Testosterone therapy and breast histopathological features in transgender individuals.

Baker GM, Guzman-Arocho YD, Bret-Mounet VC, Torous VF, Schnitt SJ, Tobias AM, Bartlett RA, Fein-Zachary VJ, Collins LC, Wulf GM, Heng YJ
Mod Pathol 2021 Jan;34(1):85-94. Epub 2020 Sep 16 doi: 10.1038/s41379-020-00675-9. PMID: 32939016 Free PMC Article

Hormonal pathology of the endometrium.

Deligdisch L
Mod Pathol 2000 Mar;13(3):285-94. doi: 10.1038/modpathol.3880050. PMID: 10757339

See all (36)

Prognosis

Pseudoangiomatous stromal hyperplasia: A clinical perspective and a brief review.

Patel G, Bipte S, Narurkar S
J Cancer Res Ther 2023 Oct 1;19(7):1714-1720. Epub 2023 Jan 3 doi: 10.4103/jcrt.jcrt_127_22. PMID: 38376269

Management of Stromal Lesions.

Yu J, Kansal K
Surg Clin North Am 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002. PMID: 36335922

Keep CALME (childhood asymmetry labium majus enlargement) and follow up.

Sechi A, Patrizi A, Vara G, Golfieri R, Neri I
J Dtsch Dermatol Ges 2021 Sep;19(9):1276-1281. Epub 2021 Jun 23 doi: 10.1111/ddg.14528. PMID: 34164912

Myofibroblastic, fibroblastic and myoid lesions of the breast.

Krings G, McIntire P, Shin SJ
Semin Diagn Pathol 2017 Sep;34(5):427-437. Epub 2017 May 28 doi: 10.1053/j.semdp.2017.05.010. PMID: 28751104

Pseudoangiomatous stromal hyperplasia: an overview.

Virk RK, Khan A
Arch Pathol Lab Med 2010 Jul;134(7):1070-4. doi: 10.5858/2008-0686-RS.1. PMID: 20586640

See all (45)

Clinical prediction guides

Pseudoangiomatous stromal hyperplasia: A clinical perspective and a brief review.

Patel G, Bipte S, Narurkar S
J Cancer Res Ther 2023 Oct 1;19(7):1714-1720. Epub 2023 Jan 3 doi: 10.4103/jcrt.jcrt_127_22. PMID: 38376269

Giant juvenile fibroadenomas with and without prominent pseudoangiomatous stromal hyperplasia (PASH)-like change: clinicopathological and molecular characteristics.

Jorns JM, Farooq A, Puzyrenko A, Jarzembowski J, Thike AA, Nasir NDM, Ng CCY, Liu W, Lee JY, Lim AH, Guan P, Teh BT, Tan PH
Histopathology 2023 Sep;83(3):357-365. Epub 2023 May 4 doi: 10.1111/his.14935. PMID: 37140543

Pseudoangiomatous stromal hyperplasia of the breast: Clinical evaluation.

Esmer AC, Tazeoglu D, Dag A
Breast Dis 2023;42(1):115-119. doi: 10.3233/BD-220070. PMID: 37066901

Management of Stromal Lesions.

Yu J, Kansal K
Surg Clin North Am 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002. PMID: 36335922

Myofibroblastic, fibroblastic and myoid lesions of the breast.

Krings G, McIntire P, Shin SJ
Semin Diagn Pathol 2017 Sep;34(5):427-437. Epub 2017 May 28 doi: 10.1053/j.semdp.2017.05.010. PMID: 28751104

See all (62)