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Thyroid Gland Medullary Carcinoma with Amyloid Stroma

MedGen UID:
83136
•Concept ID:
C0334379
•
Neoplastic Process
Synonyms: C Cell Adenocarcinoma with Amyloid Stroma; C Cell Carcinoma with Amyloid Stroma; Medullary Adenocarcinoma with Amyloid Stroma; Medullary Carcinoma with Amyloid Stroma; Medullary carcinoma with amyloid stroma; Medullary Thyroid Gland Carcinoma with Amyloid Stroma; Parafollicular Cell Adenocarcinoma with Amyloid Stroma; Parafollicular Cell Carcinoma with Amyloid Stroma
SNOMED CT: Medullary carcinoma with amyloid stroma (128916007)

Definition

A medullary thyroid gland carcinoma characterized by the presence of amyloid stroma. The majority of medullary carcinomas of the thyroid gland are associated with amyloid deposits. The latter are highlighted with Congo red staining method. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThyroid Gland Medullary Carcinoma with Amyloid Stroma

Recent clinical studies

Etiology

Identification, characterization and classification of endocrine tumours.
Wilander E, Grimelius L
Zentralbl Pathol 1993 Jun;139(2):95-100. PMID: 7690247

Diagnosis

Diagnosis and pathologic characteristics of medullary thyroid carcinoma-review of current guidelines.
Thomas CM, Asa SL, Ezzat S, Sawka AM, Goldstein D
Curr Oncol 2019 Oct;26(5):338-344. Epub 2019 Oct 1 doi: 10.3747/co.26.5539. PMID: 31708652Free PMC Article
Encapsulated cystic papillary variant of medullary carcinoma of thyroid gland.
Ozkara SK, Gürbüz Y, Müezzinoğlu B, Yumbal Z
Endocr Pathol 2002 Summer;13(2):167-71. doi: 10.1385/ep:13:2:167. PMID: 12165666
Identification, characterization and classification of endocrine tumours.
Wilander E, Grimelius L
Zentralbl Pathol 1993 Jun;139(2):95-100. PMID: 7690247
Medullary carcinoma of the thyroid.
Fierstein J, Sessions DG, Thawley SE
Laryngoscope 1976 Oct;86(10):1594-601. doi: 10.1288/00005537-197610000-00015. PMID: 966925
Medullary carcinoma of the thyroid.
Williams CR, Brewer DB
Br J Surg 1969 Jun;56(6):437-43. doi: 10.1002/bjs.1800560610. PMID: 5785544

Prognosis

Medullary carcinoma of the thyroid.
Fierstein J, Sessions DG, Thawley SE
Laryngoscope 1976 Oct;86(10):1594-601. doi: 10.1288/00005537-197610000-00015. PMID: 966925
Medullary carcinoma of the thyroid.
Williams CR, Brewer DB
Br J Surg 1969 Jun;56(6):437-43. doi: 10.1002/bjs.1800560610. PMID: 5785544

Clinical prediction guides

Encapsulated cystic papillary variant of medullary carcinoma of thyroid gland.
Ozkara SK, Gürbüz Y, Müezzinoğlu B, Yumbal Z
Endocr Pathol 2002 Summer;13(2):167-71. doi: 10.1385/ep:13:2:167. PMID: 12165666

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