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Melanoma Arising from Blue Nevus

MedGen UID:
83150
Concept ID:
C0334447
Neoplastic Process
Synonyms: Blue nevus, malignant; Blue Nevus-Like Melanoma; Malignant blue nevus; Malignant Blue Nevus; Malignant blue nevus of skin; Malignant Blue Nevus of Skin; Malignant Blue Nevus of the Skin; Malignant Cutaneous Blue Nevus; Malignant melanoma in blue nevus; Malignant Skin Blue Nevus
SNOMED CT: Blue nevus, malignant (67159000); Malignant blue nevus (67159000); Malignant melanoma in blue nevus (307603002); Malignant blue nevus of skin (307603002)

Definition

A rare melanoma which develops in a pre-existing blue nevus. It occurs more frequently on the scalp, face, orbit, back, buttocks, extremities, hands, and feet. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMelanoma Arising from Blue Nevus

Recent clinical studies

Etiology

Thangaiah JJ, Westling BE, Roden AC, Giannini C, Tetzlaff M, Cho WC, Folpe AL
Ann Diagn Pathol 2022 Aug;59:151967. Epub 2022 May 6 doi: 10.1016/j.anndiagpath.2022.151967. PMID: 35567887
Caccavale S, Calabrese G, Mattiello E, Broganelli P, Ramondetta A, Pieretti G, Alfano R, Argenziano G
Dermatology 2021;237(3):473-478. Epub 2020 Oct 14 doi: 10.1159/000510221. PMID: 33053549
Chang LW, Kazlouskaya V, Kazi R, Davar D, Ferris RL, Ho J, Karunamurthy A, Jedrych JJ, Bunimovich YL
Am J Dermatopathol 2020 Nov;42(11):854-857. doi: 10.1097/DAD.0000000000001652. PMID: 32310862Free PMC Article
Costa S, Byrne M, Pissaloux D, Haddad V, Paindavoine S, Thomas L, Aubin F, Lesimple T, Grange F, Bonniaud B, Mortier L, Mateus C, Dreno B, Balme B, Vergier B, de la Fouchardiere A
Am J Surg Pathol 2016 Mar;40(3):368-77. doi: 10.1097/PAS.0000000000000568. PMID: 26645730
Patel LM, Lambert PJ, Gagna CE, Maghari A, Lambert WC
Clin Dermatol 2011 Sep-Oct;29(5):511-22. doi: 10.1016/j.clindermatol.2011.01.019. PMID: 21855727

Diagnosis

Ledić Drvar D, Radoš J, Manola I, Mataić A, Dotlić S, Krušlin B
Acta Dermatovenerol Croat 2023 Aug;31(1):40-42. PMID: 37843090
Shah K, Folpe AL, Miller M, Morgan JA, Raut CP, Doyle LA
Histopathology 2021 Jan;78(2):281-289. Epub 2020 Oct 16 doi: 10.1111/his.14219. PMID: 32698251
Oaxaca G, Billings SD, Ko JS
J Cutan Pathol 2020 Sep;47(9):815-823. Epub 2020 Jul 6 doi: 10.1111/cup.13721. PMID: 32330325
Borgenvik TL, Karlsvik TM, Ray S, Fawzy M, James N
ANZ J Surg 2017 May;87(5):345-349. Epub 2017 Mar 20 doi: 10.1111/ans.13946. PMID: 28318130
Barnhill RL, Mihm MC Jr
Semin Diagn Pathol 1993 Feb;10(1):47-75. PMID: 8506417

Therapy

Kaleem Z, Lind AC, Humphrey PA, Sueper RH, Swanson PE, Ritter JH, Wick MR
Mod Pathol 2000 Mar;13(3):217-22. doi: 10.1038/modpathol.3880040. PMID: 10757331

Prognosis

Shah K, Folpe AL, Miller M, Morgan JA, Raut CP, Doyle LA
Histopathology 2021 Jan;78(2):281-289. Epub 2020 Oct 16 doi: 10.1111/his.14219. PMID: 32698251
Chang LW, Kazlouskaya V, Kazi R, Davar D, Ferris RL, Ho J, Karunamurthy A, Jedrych JJ, Bunimovich YL
Am J Dermatopathol 2020 Nov;42(11):854-857. doi: 10.1097/DAD.0000000000001652. PMID: 32310862Free PMC Article
Griewank KG, Müller H, Jackett LA, Emberger M, Möller I, van de Nes JA, Zimmer L, Livingstone E, Wiesner T, Scholz SL, Cosgarea I, Sucker A, Schimming T, Hillen U, Schilling B, Paschen A, Reis H, Mentzel T, Kutzner H, Rütten A, Murali R, Scolyer RA, Schadendorf D
Mod Pathol 2017 Jul;30(7):928-939. Epub 2017 Apr 14 doi: 10.1038/modpathol.2017.23. PMID: 28409567Free PMC Article
Borgenvik TL, Karlsvik TM, Ray S, Fawzy M, James N
ANZ J Surg 2017 May;87(5):345-349. Epub 2017 Mar 20 doi: 10.1111/ans.13946. PMID: 28318130
Ribé A
J Cutan Pathol 2008 Nov;35 Suppl 2:24-7. doi: 10.1111/j.1600-0560.2008.01150.x. PMID: 18976416

Clinical prediction guides

Borgenvik TL, Karlsvik TM, Ray S, Fawzy M, James N
ANZ J Surg 2017 May;87(5):345-349. Epub 2017 Mar 20 doi: 10.1111/ans.13946. PMID: 28318130
Costa S, Byrne M, Pissaloux D, Haddad V, Paindavoine S, Thomas L, Aubin F, Lesimple T, Grange F, Bonniaud B, Mortier L, Mateus C, Dreno B, Balme B, Vergier B, de la Fouchardiere A
Am J Surg Pathol 2016 Mar;40(3):368-77. doi: 10.1097/PAS.0000000000000568. PMID: 26645730
Yilmaz I, Gamsizkan M, Kucukodaci Z, Berber U, Demirel D, Haholu A, Narli G
Indian J Pathol Microbiol 2015 Jul-Sep;58(3):279-84. doi: 10.4103/0377-4929.162831. PMID: 26275246
Patel LM, Lambert PJ, Gagna CE, Maghari A, Lambert WC
Clin Dermatol 2011 Sep-Oct;29(5):511-22. doi: 10.1016/j.clindermatol.2011.01.019. PMID: 21855727
Ribé A
J Cutan Pathol 2008 Nov;35 Suppl 2:24-7. doi: 10.1111/j.1600-0560.2008.01150.x. PMID: 18976416

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