U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ameloblastic Fibrosarcoma

MedGen UID:
83168
•Concept ID:
C0334573
•
Neoplastic Process
Synonyms: Ameloblastic fibrosarcoma; Ameloblastic sarcoma; Odontogenic fibrosarcoma
SNOMED CT: Ameloblastic fibrosarcoma (27092008); Ameloblastic sarcoma (27092008); Odontogenic fibrosarcoma (27092008)

Definition

A locally aggressive malignant neoplasm arising from odontogenic tissue. It occurs in the mandible and less often in the maxilla. It is characterized by the presence of a malignant connective tissue component and a benign epithelial component. The frequency of distal metastases is low. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmeloblastic Fibrosarcoma

Professional guidelines

PubMed

Differential diagnosis of pediatric tumors of the nasal cavity and paranasal sinuses: a 45-year multi-institutional review.
Holsinger FC, Hafemeister AC, Hicks MJ, Sulek M, Huh WW, Friedman EM
Ear Nose Throat J 2010 Nov;89(11):534-40. PMID: 21086277

Recent clinical studies

Etiology

Ameloblastic fibroma and ameloblastic fibrosarcoma: A systematic review.
Chrcanovic BR, Brennan PA, Rahimi S, Gomez RS
J Oral Pathol Med 2018 Apr;47(4):315-325. Epub 2017 Sep 2 doi: 10.1111/jop.12622. PMID: 28776760
Survival and Prognosis for Malignant Tumors of Odontogenic Origin.
Agarwal S, Mark J, Xie C, Ghulam E, Patil Y
Otolaryngol Head Neck Surg 2016 Jul;155(1):113-6. Epub 2016 Mar 29 doi: 10.1177/0194599816639540. PMID: 27026731
Ameloblastic fibrosarcoma: report of a case, study of immunophenotype, and comprehensive review of the literature.
Lai J, Blanas N, Higgins K, Klieb H
J Oral Maxillofac Surg 2012 Aug;70(8):2007-12. Epub 2011 Dec 16 doi: 10.1016/j.joms.2011.09.012. PMID: 22177804
Malignant transformation of ameloblastic fibroma to ameloblastic fibrosarcoma: case report and review of the literature.
Kobayashi K, Murakami R, Fujii T, Hirano A
J Craniomaxillofac Surg 2005 Oct;33(5):352-5. doi: 10.1016/j.jcms.2005.04.006. PMID: 16129612
Ameloblastic fibrosarcoma: report of a case. Immunohistochemical study and review of the literature.
Huguet P, Castellví J, Avila M, Alejo M, Autonell F, Basas C, Bescos MS
Med Oral 2001 May-Jul;6(3):173-9. PMID: 11500634

Diagnosis

The molecular basis of odontogenic cysts and tumours.
Gomes IP, Bastos VC, Guimarães LM, Gomes CC
J Oral Pathol Med 2023 Apr;52(4):351-356. Epub 2023 Jan 23 doi: 10.1111/jop.13401. PMID: 36629457
Ameloblastic fibroma and ameloblastic fibrosarcoma: A systematic review.
Chrcanovic BR, Brennan PA, Rahimi S, Gomez RS
J Oral Pathol Med 2018 Apr;47(4):315-325. Epub 2017 Sep 2 doi: 10.1111/jop.12622. PMID: 28776760
Ameloblastic Fibrosarcoma: A Case Report and Literature Review.
Servato JPS, Faria PR, Ribeiro CV, Cardoso SV, Faria PR, Dias FL, Eisenberg ALA, Loyola AM
Braz Dent J 2017 Mar-Apr;28(2):262-272. doi: 10.1590/0103-6440201701050. PMID: 28492759
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Ameloblastic fibrosarcoma.
Sözeri B, Ataman M, Ruacan S, Gedikoglu G
Int J Pediatr Otorhinolaryngol 1993 Jan;25(1-3):255-9. doi: 10.1016/0165-5876(93)90061-7. PMID: 8436474

Prognosis

Ameloblastic Fibro-Odontoma in an Adolescent: A Case Report and Review of Literature.
Peters SM, Bergen MS, Philipone EM, Yoon AJ
J Clin Pediatr Dent 2018;42(6):458-460. Epub 2018 Aug 7 doi: 10.17796/1053-4625-42.6.10. PMID: 30085878
Ameloblastic Fibrosarcoma: A Case Report and Literature Review.
Servato JPS, Faria PR, Ribeiro CV, Cardoso SV, Faria PR, Dias FL, Eisenberg ALA, Loyola AM
Braz Dent J 2017 Mar-Apr;28(2):262-272. doi: 10.1590/0103-6440201701050. PMID: 28492759
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Survival and Prognosis for Malignant Tumors of Odontogenic Origin.
Agarwal S, Mark J, Xie C, Ghulam E, Patil Y
Otolaryngol Head Neck Surg 2016 Jul;155(1):113-6. Epub 2016 Mar 29 doi: 10.1177/0194599816639540. PMID: 27026731
Malignant transformation of ameloblastic fibroma to ameloblastic fibrosarcoma: case report and review of the literature.
Kobayashi K, Murakami R, Fujii T, Hirano A
J Craniomaxillofac Surg 2005 Oct;33(5):352-5. doi: 10.1016/j.jcms.2005.04.006. PMID: 16129612

Clinical prediction guides

Comparison of fatty acid synthase and cyclooxygenase-2 immunoexpression in embryonal, benign, and malignant odontogenic tissues.
Sánchez-Romero C, Mosqueda-Taylor A, Delgado-Azañero W, Paes de Almedia O, Bologna-Molina R
Oral Surg Oral Med Oral Pathol Oral Radiol 2019 Apr;127(4):309-317. Epub 2018 Dec 31 doi: 10.1016/j.oooo.2018.12.020. PMID: 30692057
Odontogenic tumors: A 35-year retrospective study of 250 cases in an Indian (Maharashtra) teaching institute.
Ahire MS, Tupkari JV, Chettiankandy TJ, Thakur A, Agrawal RR
Indian J Cancer 2018 Jul-Sep;55(3):265-272. doi: 10.4103/ijc.IJC_145_18. PMID: 30693892
Ameloblastic Fibro-Odontoma in an Adolescent: A Case Report and Review of Literature.
Peters SM, Bergen MS, Philipone EM, Yoon AJ
J Clin Pediatr Dent 2018;42(6):458-460. Epub 2018 Aug 7 doi: 10.17796/1053-4625-42.6.10. PMID: 30085878
Ameloblastic fibrosarcoma of the mandible: report of two cases and review of the literature.
Bregni RC, Taylor AM, García AM
J Oral Pathol Med 2001 May;30(5):316-20. doi: 10.1034/j.1600-0714.2001.300510.x. PMID: 11334469
Ameloblastic fibrosarcoma.
Sözeri B, Ataman M, Ruacan S, Gedikoglu G
Int J Pediatr Otorhinolaryngol 1993 Jan;25(1-3):255-9. doi: 10.1016/0165-5876(93)90061-7. PMID: 8436474

Recent systematic reviews

Ameloblastic fibroma and ameloblastic fibrosarcoma: A systematic review.
Chrcanovic BR, Brennan PA, Rahimi S, Gomez RS
J Oral Pathol Med 2018 Apr;47(4):315-325. Epub 2017 Sep 2 doi: 10.1111/jop.12622. PMID: 28776760
Ameloblastic Fibrosarcoma: A Case Report and Literature Review.
Servato JPS, Faria PR, Ribeiro CV, Cardoso SV, Faria PR, Dias FL, Eisenberg ALA, Loyola AM
Braz Dent J 2017 Mar-Apr;28(2):262-272. doi: 10.1590/0103-6440201701050. PMID: 28492759

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...