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Metastatic malignant neoplasm in the colon

MedGen UID:
83432
Concept ID:
C0346974
Neoplastic Process
Synonyms: Metastatic Malignant Neoplasm in the Colon; metastatic malignant neoplasm in the colon; Metastatic malignant neoplasm of colon; Metastatic malignant neoplasm to colon; Metastatic Malignant Neoplasm to the Colon; metastatic malignant neoplasm to the colon; Metastatic Neoplasm to the Colon; metastatic neoplasm to the colon; Metastatic Tumor to the Colon; metastatic tumor to the colon; metastatic tumour to the colon; Secondary malignant neoplasm of colon
SNOMED CT: Secondary malignant neoplasm of colon (94260004); Metastatic malignant neoplasm to colon (94260004); Metastatic malignant neoplasm of colon (94260004)
 
Monarch Initiative: MONDO:0041447

Definition

The spread of a malignant neoplasm to the colon. This may be from a primary large intestine malignant neoplasm, or from a malignant neoplasm at a distant site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic malignant neoplasm in the colon

Professional guidelines

PubMed

Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Morris VK, Kennedy EB, Baxter NN, Benson AB 3rd, Cercek A, Cho M, Ciombor KK, Cremolini C, Davis A, Deming DA, Fakih MG, Gholami S, Hong TS, Jaiyesimi I, Klute K, Lieu C, Sanoff H, Strickler JH, White S, Willis JA, Eng C
J Clin Oncol 2023 Jan 20;41(3):678-700. Epub 2022 Oct 17 doi: 10.1200/JCO.22.01690. PMID: 36252154Free PMC Article
Benson AB, Venook AP, Al-Hawary MM, Arain MA, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Farkas L, Garrido-Laguna I, Grem JL, Gunn A, Hecht JR, Hoffe S, Hubbard J, Hunt S, Johung KL, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Miller ED, Mulcahy MF, Nurkin S, Overman MJ, Parikh A, Patel H, Pedersen K, Saltz L, Schneider C, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Gregory KM, Gurski LA
J Natl Compr Canc Netw 2021 Mar 2;19(3):329-359. doi: 10.6004/jnccn.2021.0012. PMID: 33724754

Recent clinical studies

Etiology

Vera R, Salgado M, Safont MJ, Gallego J, González E, Élez E, Aranda E
Clin Transl Oncol 2021 Apr;23(4):827-839. Epub 2020 Aug 13 doi: 10.1007/s12094-020-02475-8. PMID: 32789773Free PMC Article
Repici A, Badalamenti M, Maselli R, Correale L, Radaelli F, Rondonotti E, Ferrara E, Spadaccini M, Alkandari A, Fugazza A, Anderloni A, Galtieri PA, Pellegatta G, Carrara S, Di Leo M, Craviotto V, Lamonaca L, Lorenzetti R, Andrealli A, Antonelli G, Wallace M, Sharma P, Rosch T, Hassan C
Gastroenterology 2020 Aug;159(2):512-520.e7. Epub 2020 May 1 doi: 10.1053/j.gastro.2020.04.062. PMID: 32371116
Kim EK, Song MJ, Jung Y, Lee WS, Jang HH
Cancer Genomics Proteomics 2019 Nov-Dec;16(6):583-592. doi: 10.21873/cgp.20161. PMID: 31659112Free PMC Article
Zeng H, Umar S, Rust B, Lazarova D, Bordonaro M
Int J Mol Sci 2019 Mar 11;20(5) doi: 10.3390/ijms20051214. PMID: 30862015Free PMC Article
Wang S, Miao Z, Yang Q, Wang Y, Zhang J
Can J Gastroenterol Hepatol 2018;2018:7628763. Epub 2018 Nov 7 doi: 10.1155/2018/7628763. PMID: 30533404Free PMC Article

Diagnosis

Repici A, Badalamenti M, Maselli R, Correale L, Radaelli F, Rondonotti E, Ferrara E, Spadaccini M, Alkandari A, Fugazza A, Anderloni A, Galtieri PA, Pellegatta G, Carrara S, Di Leo M, Craviotto V, Lamonaca L, Lorenzetti R, Andrealli A, Antonelli G, Wallace M, Sharma P, Rosch T, Hassan C
Gastroenterology 2020 Aug;159(2):512-520.e7. Epub 2020 May 1 doi: 10.1053/j.gastro.2020.04.062. PMID: 32371116
Villalba M, Evans SR, Vidal-Vanaclocha F, Calvo A
Cell Tissue Res 2017 Oct;370(1):29-39. Epub 2017 May 30 doi: 10.1007/s00441-017-2633-9. PMID: 28560691
Tauriello DV, Calon A, Lonardo E, Batlle E
Mol Oncol 2017 Jan;11(1):97-119. Epub 2017 Jan 3 doi: 10.1002/1878-0261.12018. PMID: 28085225Free PMC Article
Aarons CB, Shanmugan S, Bleier JI
World J Gastroenterol 2014 Nov 21;20(43):16178-83. doi: 10.3748/wjg.v20.i43.16178. PMID: 25473171Free PMC Article
Riemann JF
Digestion 2013;87(3):139-40. Epub 2013 Mar 14 doi: 10.1159/000346848. PMID: 23548625

Therapy

Taraborrelli L, Şenbabaoğlu Y, Wang L, Lim J, Blake K, Kljavin N, Gierke S, Scherl A, Ziai J, McNamara E, Owyong M, Rao S, Calviello AK, Oreper D, Jhunjhunwala S, Argiles G, Bendell J, Kim TW, Ciardiello F, Wongchenko MJ, de Sauvage FJ, de Sousa E Melo F, Yan Y, West NR, Murthy A
Nat Commun 2023 Sep 23;14(1):5945. doi: 10.1038/s41467-023-41618-7. PMID: 37741832Free PMC Article
Dasari A, Sobrero A, Yao J, Yoshino T, Schelman W, Yang Z, Chien C, Kania M, Tabernero J, Eng C
Future Oncol 2021 Aug;17(24):3151-3162. Epub 2021 May 17 doi: 10.2217/fon-2021-0202. PMID: 33993740
Repici A, Badalamenti M, Maselli R, Correale L, Radaelli F, Rondonotti E, Ferrara E, Spadaccini M, Alkandari A, Fugazza A, Anderloni A, Galtieri PA, Pellegatta G, Carrara S, Di Leo M, Craviotto V, Lamonaca L, Lorenzetti R, Andrealli A, Antonelli G, Wallace M, Sharma P, Rosch T, Hassan C
Gastroenterology 2020 Aug;159(2):512-520.e7. Epub 2020 May 1 doi: 10.1053/j.gastro.2020.04.062. PMID: 32371116
Kim EK, Song MJ, Jung Y, Lee WS, Jang HH
Cancer Genomics Proteomics 2019 Nov-Dec;16(6):583-592. doi: 10.21873/cgp.20161. PMID: 31659112Free PMC Article
Giovannucci E
Gastroenterol Clin North Am 2002 Dec;31(4):925-43. doi: 10.1016/s0889-8553(02)00057-2. PMID: 12489270

Prognosis

Hemminki J, Försti A, Hemminki A, Hemminki K
Eur J Cancer 2022 Nov;175:77-85. Epub 2022 Sep 9 doi: 10.1016/j.ejca.2022.08.015. PMID: 36096040
Kim K, Kim YW, Shim H, Kim BR, Kwon HY
J BUON 2018 Dec;23(7):11-18. PMID: 30722106
Tauriello DV, Calon A, Lonardo E, Batlle E
Mol Oncol 2017 Jan;11(1):97-119. Epub 2017 Jan 3 doi: 10.1002/1878-0261.12018. PMID: 28085225Free PMC Article
Nobili S, Galletta A, Brugia M, Tassi R, Petreni P, Landini I, Mini E
Future Med Chem 2015 Aug;7(12):1491-501. Epub 2015 Aug 21 doi: 10.4155/fmc.15.85. PMID: 26293581
Sipos F, Muzes G
World J Gastroenterol 2011 Apr 7;17(13):1666-73. doi: 10.3748/wjg.v17.i13.1666. PMID: 21483625Free PMC Article

Clinical prediction guides

Xu YX, Huang Y, Wang XJ, Ye DX, Chi P
Cancer Med 2022 Jun;11(12):2366-2376. Epub 2022 Apr 18 doi: 10.1002/cam4.4626. PMID: 35437894Free PMC Article
van Pelt GW, Kjær-Frifeldt S, van Krieken JHJM, Al Dieri R, Morreau H, Tollenaar RAEM, Sørensen FB, Mesker WE
Virchows Arch 2018 Oct;473(4):405-412. Epub 2018 Jul 20 doi: 10.1007/s00428-018-2408-z. PMID: 30030621Free PMC Article
Copija A, Waniczek D, Witkoś A, Walkiewicz K, Nowakowska-Zajdel E
Int J Mol Sci 2017 Jan 6;18(1) doi: 10.3390/ijms18010107. PMID: 28067827Free PMC Article
Miettinen M, McCue PA, Sarlomo-Rikala M, Rys J, Czapiewski P, Wazny K, Langfort R, Waloszczyk P, Biernat W, Lasota J, Wang Z
Am J Surg Pathol 2014 Jan;38(1):13-22. doi: 10.1097/PAS.0b013e3182a0218f. PMID: 24145643Free PMC Article
Naba A, Clauser KR, Hoersch S, Liu H, Carr SA, Hynes RO
Mol Cell Proteomics 2012 Apr;11(4):M111.014647. Epub 2011 Dec 9 doi: 10.1074/mcp.M111.014647. PMID: 22159717Free PMC Article

Recent systematic reviews

Morris VK, Kennedy EB, Baxter NN, Benson AB 3rd, Cercek A, Cho M, Ciombor KK, Cremolini C, Davis A, Deming DA, Fakih MG, Gholami S, Hong TS, Jaiyesimi I, Klute K, Lieu C, Sanoff H, Strickler JH, White S, Willis JA, Eng C
J Clin Oncol 2023 Jan 20;41(3):678-700. Epub 2022 Oct 17 doi: 10.1200/JCO.22.01690. PMID: 36252154Free PMC Article
Cuk P, Kjær MD, Mogensen CB, Nielsen MF, Pedersen AK, Ellebæk MB
Surg Endosc 2022 Jan;36(1):32-46. Epub 2021 Nov 1 doi: 10.1007/s00464-021-08782-7. PMID: 34724576Free PMC Article
Formica V, Sera F, Cremolini C, Riondino S, Morelli C, Arkenau HT, Roselli M
J Natl Cancer Inst 2022 Apr 11;114(4):517-527. doi: 10.1093/jnci/djab190. PMID: 34542636Free PMC Article
O'Sullivan DE, Sutherland RL, Town S, Chow K, Fan J, Forbes N, Heitman SJ, Hilsden RJ, Brenner DR
Clin Gastroenterol Hepatol 2022 Jun;20(6):1229-1240.e5. Epub 2021 Jan 29 doi: 10.1016/j.cgh.2021.01.037. PMID: 33524598
Hassan C, Spadaccini M, Iannone A, Maselli R, Jovani M, Chandrasekar VT, Antonelli G, Yu H, Areia M, Dinis-Ribeiro M, Bhandari P, Sharma P, Rex DK, Rösch T, Wallace M, Repici A
Gastrointest Endosc 2021 Jan;93(1):77-85.e6. Epub 2020 Jun 26 doi: 10.1016/j.gie.2020.06.059. PMID: 32598963

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