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Colonic neoplasm

MedGen UID:
3165
•Concept ID:
C0009375
•
Neoplastic Process
Synonyms: Colonic Neoplasms; Neoplasm of the colon
SNOMED CT: Neoplasm of colon (126838000); Tumor of colon (126838000)
 
HPO: HP:0100273
Monarch Initiative: MONDO:0005401

Definition

A benign or malignant neoplasm that affects the colon. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colonic adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColonic neoplasm

Professional guidelines

PubMed

Results of a national survey on the use of stents for the treatment of colonic obstruction.
Alonso-Hernández N, Segura-Sampedro JJ, Soldevila Verdeguer CM, Ochogavía Seguí A, Olea Martinez-Mediero JM, Fernández Isart M, Gamundi Cuesta M, González-Argente XF
Cir Esp (Engl Ed) 2020 Nov;98(9):533-539. Epub 2020 Mar 24 doi: 10.1016/j.ciresp.2020.02.006. PMID: 32220416
Evolution of surgical microwave ablation for the treatment of colorectal cancer liver metastasis: review of the literature and a single centre experience.
Stättner S, Primavesi F, Yip VS, Jones RP, Öfner D, Malik HZ, Fenwick SW, Poston GJ
Surg Today 2015 Apr;45(4):407-15. Epub 2014 Mar 16 doi: 10.1007/s00595-014-0879-3. PMID: 24633931
Symptomatic colonic lipoma: differential diagnosis of large bowel tumors.
Bardají M, Roset F, Camps R, Sant F, Fernández-Layos MJ
Int J Colorectal Dis 1998;13(1):1-2. doi: 10.1007/s003840050122. PMID: 9548092

Recent clinical studies

Etiology

Optimal glycaemic control and the reduced risk of colorectal adenoma and cancer in patients with diabetes: a population-based cohort study.
Mao X, Cheung KS, Tan JT, Mak LY, Lee CH, Chiang CL, Cheng HM, Hui RW, Yuen MF, Leung WK, Seto WK
Gut 2024 Jul 11;73(8):1313-1320. doi: 10.1136/gutjnl-2023-331701. PMID: 38569845
Randomized controlled trial of EndoRings assisted colonoscopy versus standard colonoscopy.
Thayalasekaran S, Bhattacharyya R, Chedgy F, Basford P, Subramaniam S, Kandiah K, Thursby-Pelham F, Brown J, Alkandari A, Ellis R, Coda S, Goggin P, Amos M, Fogg C, Longcroft-Wheaton G, Bhandari P
Dig Endosc 2023 Mar;35(3):354-360. Epub 2022 Oct 27 doi: 10.1111/den.14432. PMID: 36085410
Endoscopic Stenting for Malignant Left-Sided Large-Bowel Obstruction in Patients with Colorectal Cancer: Evaluation according to Pathological Stage.
Oh Y, Yoon S, Lim SG, Oh SY
Dig Surg 2022;39(5-6):242-249. Epub 2022 Nov 21 doi: 10.1159/000528181. PMID: 36412630
Colon Carcinogenesis: The Interplay Between Diet and Gut Microbiota.
Loke YL, Chew MT, Ngeow YF, Lim WWD, Peh SC
Front Cell Infect Microbiol 2020;10:603086. Epub 2020 Dec 8 doi: 10.3389/fcimb.2020.603086. PMID: 33364203Free PMC Article
The risk of colonic adenomas and colonic cancer in obesity.
Laiyemo AO
Best Pract Res Clin Gastroenterol 2014 Aug;28(4):655-63. Epub 2014 Jul 10 doi: 10.1016/j.bpg.2014.07.007. PMID: 25194182Free PMC Article

Diagnosis

Optimal glycaemic control and the reduced risk of colorectal adenoma and cancer in patients with diabetes: a population-based cohort study.
Mao X, Cheung KS, Tan JT, Mak LY, Lee CH, Chiang CL, Cheng HM, Hui RW, Yuen MF, Leung WK, Seto WK
Gut 2024 Jul 11;73(8):1313-1320. doi: 10.1136/gutjnl-2023-331701. PMID: 38569845
Precision endoscopy in the era of climate change and sustainability.
Ueda T, Li JW, Ho SH, Singh R, Uedo N
J Gastroenterol Hepatol 2024 Jan;39(1):18-27. Epub 2023 Oct 26 doi: 10.1111/jgh.16383. PMID: 37881033
Factors contributing to time to diagnosis in symptomatic colorectal cancer: A scoping review.
Golding H, Webber CE, Groome PA
Eur J Cancer Care (Engl) 2021 May;30(3):e13397. Epub 2020 Dec 30 doi: 10.1111/ecc.13397. PMID: 33377574
Metabolic dysfunction and early-onset colorectal cancer - how macrophages build the bridge.
Scheurlen KM, Billeter AT, O'Brien SJ, Galandiuk S
Cancer Med 2020 Sep;9(18):6679-6693. Epub 2020 Jul 23 doi: 10.1002/cam4.3315. PMID: 33624450Free PMC Article
Appendicitis in the elderly.
Lee JF, Leow CK, Lau WY
Aust N Z J Surg 2000 Aug;70(8):593-6. doi: 10.1046/j.1440-1622.2000.01905.x. PMID: 10945554

Therapy

Randomized controlled trial of EndoRings assisted colonoscopy versus standard colonoscopy.
Thayalasekaran S, Bhattacharyya R, Chedgy F, Basford P, Subramaniam S, Kandiah K, Thursby-Pelham F, Brown J, Alkandari A, Ellis R, Coda S, Goggin P, Amos M, Fogg C, Longcroft-Wheaton G, Bhandari P
Dig Endosc 2023 Mar;35(3):354-360. Epub 2022 Oct 27 doi: 10.1111/den.14432. PMID: 36085410
Results of a national survey on the use of stents for the treatment of colonic obstruction.
Alonso-Hernández N, Segura-Sampedro JJ, Soldevila Verdeguer CM, Ochogavía Seguí A, Olea Martinez-Mediero JM, Fernández Isart M, Gamundi Cuesta M, González-Argente XF
Cir Esp (Engl Ed) 2020 Nov;98(9):533-539. Epub 2020 Mar 24 doi: 10.1016/j.ciresp.2020.02.006. PMID: 32220416
Results of colon cancer surgery in patients over 75 years old.
Pérez Domínguez L, Cáceres Alvarado N, Toscano Novella Á, Casal Núñez JE
ANZ J Surg 2018 Jan;88(1-2):E11-E15. Epub 2016 Aug 26 doi: 10.1111/ans.13666. PMID: 27566595
Rethinking Priorities: Cost of Complications After Elective Colectomy.
Zogg CK, Najjar P, Diaz AJ, Zogg DL, Tsai TC, Rose JA Jr, Scott JW, Gani F, Alshaikh H, Canner JK, Schneider EB, Goldberg JE, Haider AH
Ann Surg 2016 Aug;264(2):312-22. doi: 10.1097/SLA.0000000000001511. PMID: 26501705
Appendicitis in the elderly.
Lee JF, Leow CK, Lau WY
Aust N Z J Surg 2000 Aug;70(8):593-6. doi: 10.1046/j.1440-1622.2000.01905.x. PMID: 10945554

Prognosis

Endoscopic Stenting for Malignant Left-Sided Large-Bowel Obstruction in Patients with Colorectal Cancer: Evaluation according to Pathological Stage.
Oh Y, Yoon S, Lim SG, Oh SY
Dig Surg 2022;39(5-6):242-249. Epub 2022 Nov 21 doi: 10.1159/000528181. PMID: 36412630
Undifferentiated colonic neoplasm with SMARCA4 germline gene mutation and loss of SMARCA4 protein expression: a case report and literature review.
Duan H, Gao W, Wang L, Cao F, Teng L
Diagn Pathol 2021 Apr 9;16(1):30. doi: 10.1186/s13000-021-01091-6. PMID: 33836796Free PMC Article
Metabolic dysfunction and early-onset colorectal cancer - how macrophages build the bridge.
Scheurlen KM, Billeter AT, O'Brien SJ, Galandiuk S
Cancer Med 2020 Sep;9(18):6679-6693. Epub 2020 Jul 23 doi: 10.1002/cam4.3315. PMID: 33624450Free PMC Article
Results of colon cancer surgery in patients over 75 years old.
Pérez Domínguez L, Cáceres Alvarado N, Toscano Novella Á, Casal Núñez JE
ANZ J Surg 2018 Jan;88(1-2):E11-E15. Epub 2016 Aug 26 doi: 10.1111/ans.13666. PMID: 27566595
Systemic inflammatory markers as prognostic factors in stage IIA colorectal cancer.
Park BK, Park JW, Han EC, Ryoo SB, Han SW, Kim TY, Chie EK, Jeong SY, Park KJ
J Surg Oncol 2016 Aug;114(2):216-21. Epub 2016 May 24 doi: 10.1002/jso.24299. PMID: 27222402

Clinical prediction guides

Optimal glycaemic control and the reduced risk of colorectal adenoma and cancer in patients with diabetes: a population-based cohort study.
Mao X, Cheung KS, Tan JT, Mak LY, Lee CH, Chiang CL, Cheng HM, Hui RW, Yuen MF, Leung WK, Seto WK
Gut 2024 Jul 11;73(8):1313-1320. doi: 10.1136/gutjnl-2023-331701. PMID: 38569845
Endoscopic Stenting for Malignant Left-Sided Large-Bowel Obstruction in Patients with Colorectal Cancer: Evaluation according to Pathological Stage.
Oh Y, Yoon S, Lim SG, Oh SY
Dig Surg 2022;39(5-6):242-249. Epub 2022 Nov 21 doi: 10.1159/000528181. PMID: 36412630
Prediction of advanced colonic neoplasm in symptomatic patients: a scoring system to prioritize colonoscopy (COLONOFIT study).
Fernández-Bañares F, Clèries R, Boadas J, Ribes J, Oliva JC, Alsius A, Sanz X, Martínez-Bauer E, Galter S, Pujals M, Pujol M, Del Pozo P, Campo R
BMC Cancer 2019 Jul 25;19(1):734. doi: 10.1186/s12885-019-5926-4. PMID: 31345180Free PMC Article
Results of colon cancer surgery in patients over 75 years old.
Pérez Domínguez L, Cáceres Alvarado N, Toscano Novella Á, Casal Núñez JE
ANZ J Surg 2018 Jan;88(1-2):E11-E15. Epub 2016 Aug 26 doi: 10.1111/ans.13666. PMID: 27566595
Appendicitis in the elderly.
Lee JF, Leow CK, Lau WY
Aust N Z J Surg 2000 Aug;70(8):593-6. doi: 10.1046/j.1440-1622.2000.01905.x. PMID: 10945554

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