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Adult Unfavorable Prognosis Hodgkin Lymphoma

MedGen UID:
859685
Concept ID:
C3900091
Neoplastic Process

Definition

A Hodgkin lymphoma with unfavorable prognosis that occurs during adulthood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult Unfavorable Prognosis Hodgkin Lymphoma

Professional guidelines

PubMed

Shustov A, Soma L
Cancer Treat Res 2019;176:127-144. doi: 10.1007/978-3-319-99716-2_6. PMID: 30596216
Böll B, Görgen H
Br J Haematol 2019 Jan;184(1):82-92. Epub 2018 Nov 8 doi: 10.1111/bjh.15652. PMID: 30407626
Diehl V, Thomas RK, Re D
Lancet Oncol 2004 Jan;5(1):19-26. doi: 10.1016/s1470-2045(03)01320-2. PMID: 14700605

Recent clinical studies

Etiology

Di Ciaccio PR, Polizzotto MN, Cwynarski K, Gerrie AS, Burton C, Bower M, Kuruvilla J, Montoto S, McKay P, Fox CP, Milliken S, Jiamsakul A, Osborne W, Collins GP, Manos K, Linton KM, Iyengar S, Kassam S, Limei MP, Kliman D, Wong Doo N, Watson AM, Fedele P, Yannakou CK, Hunt S, Ku M, Sehn LH, Smith A, Renshaw H, Maxwell A, Liu Q, Dhairyawan R, Ferguson G, Pickard K, Painter D, Thakrar N, Song KW, Hamad N
Blood 2024 Jan 11;143(2):152-165. doi: 10.1182/blood.2023021348. PMID: 37832030
Cazelles C, Belhadj K, Vellemans H, Camus V, Poullot E, Gaulard P, Veresezan L, Itti E, Becker S, Carvalho M, Dupuis J, Le Bras F, Lemonnier F, Roulin L, El Gnaoui T, Jardin F, Mounier N, Tilly H, Haioun C
Leuk Lymphoma 2021 Sep;62(9):2161-2168. Epub 2021 Mar 25 doi: 10.1080/10428194.2021.1901090. PMID: 33764240
Bröckelmann PJ, Goergen H, Keller U, Meissner J, Ordemann R, Halbsguth TV, Sasse S, Sökler M, Kerkhoff A, Mathas S, Hüttmann A, Bormann M, Zimmermann A, Mettler J, Fuchs M, von Tresckow B, Baues C, Rosenwald A, Klapper W, Kobe C, Borchmann P, Engert A
JAMA Oncol 2020 Jun 1;6(6):872-880. doi: 10.1001/jamaoncol.2020.0750. PMID: 32352505Free PMC Article
André MPE, Girinsky T, Federico M, Reman O, Fortpied C, Gotti M, Casasnovas O, Brice P, van der Maazen R, Re A, Edeline V, Fermé C, van Imhoff G, Merli F, Bouabdallah R, Sebban C, Specht L, Stamatoullas A, Delarue R, Fiaccadori V, Bellei M, Raveloarivahy T, Versari A, Hutchings M, Meignan M, Raemaekers J
J Clin Oncol 2017 Jun 1;35(16):1786-1794. Epub 2017 Mar 14 doi: 10.1200/JCO.2016.68.6394. PMID: 28291393
Moskowitz CH, Nademanee A, Masszi T, Agura E, Holowiecki J, Abidi MH, Chen AI, Stiff P, Gianni AM, Carella A, Osmanov D, Bachanova V, Sweetenham J, Sureda A, Huebner D, Sievers EL, Chi A, Larsen EK, Hunder NN, Walewski J; AETHERA Study Group
Lancet 2015 May 9;385(9980):1853-62. Epub 2015 Mar 19 doi: 10.1016/S0140-6736(15)60165-9. PMID: 25796459

Diagnosis

Di Ciaccio PR, Polizzotto MN, Cwynarski K, Gerrie AS, Burton C, Bower M, Kuruvilla J, Montoto S, McKay P, Fox CP, Milliken S, Jiamsakul A, Osborne W, Collins GP, Manos K, Linton KM, Iyengar S, Kassam S, Limei MP, Kliman D, Wong Doo N, Watson AM, Fedele P, Yannakou CK, Hunt S, Ku M, Sehn LH, Smith A, Renshaw H, Maxwell A, Liu Q, Dhairyawan R, Ferguson G, Pickard K, Painter D, Thakrar N, Song KW, Hamad N
Blood 2024 Jan 11;143(2):152-165. doi: 10.1182/blood.2023021348. PMID: 37832030
Borchmann P, Plütschow A, Kobe C, Greil R, Meissner J, Topp MS, Ostermann H, Dierlamm J, Mohm J, Thiemer J, Sökler M, Kerkhoff A, Ahlborn M, Halbsguth TV, Martin S, Keller U, Balabanov S, Pabst T, Vogelhuber M, Hüttmann A, Wilhelm M, Zijlstra JM, Moccia A, Kuhnert G, Bröckelmann PJ, von Tresckow B, Fuchs M, Klimm B, Rosenwald A, Eich H, Baues C, Marnitz S, Hallek M, Diehl V, Dietlein M, Engert A
Lancet Oncol 2021 Feb;22(2):223-234. doi: 10.1016/S1470-2045(20)30601-X. PMID: 33539742
Böll B, Görgen H
Br J Haematol 2019 Jan;184(1):82-92. Epub 2018 Nov 8 doi: 10.1111/bjh.15652. PMID: 30407626
Borchmann S, Engert A, Böll B
Curr Opin Oncol 2018 Sep;30(5):308-316. doi: 10.1097/CCO.0000000000000464. PMID: 29994901
Mottok A, Steidl C
Blood 2018 Apr 12;131(15):1654-1665. Epub 2018 Mar 2 doi: 10.1182/blood-2017-09-772632. PMID: 29500175

Therapy

Izutsu K, Makita S, Nosaka K, Yoshimitsu M, Utsunomiya A, Kusumoto S, Morishima S, Tsukasaki K, Kawamata T, Ono T, Rai S, Katsuya H, Ishikawa J, Yamada H, Kato K, Tachibana M, Kakurai Y, Adachi N, Tobinai K, Yonekura K, Ishitsuka K
Blood 2023 Mar 9;141(10):1159-1168. doi: 10.1182/blood.2022016862. PMID: 36150143Free PMC Article
Fornecker LM, Lazarovici J, Aurer I, Casasnovas RO, Gac AC, Bonnet C, Bouabdallah K, Feugier P, Specht L, Molina L, Touati M, Borel C, Stamatoullas A, Nicolas-Virelizier E, Pascal L, Lugtenburg P, Di Renzo N, Vander Borght T, Traverse-Glehen A, Dartigues P, Hutchings M, Versari A, Meignan M, Federico M, André M; LYSA-FIL-EORTC Intergroup
J Clin Oncol 2023 Jan 10;41(2):327-335. Epub 2022 Jul 22 doi: 10.1200/JCO.21.01281. PMID: 35867960
Bröckelmann PJ, Goergen H, Keller U, Meissner J, Ordemann R, Halbsguth TV, Sasse S, Sökler M, Kerkhoff A, Mathas S, Hüttmann A, Bormann M, Zimmermann A, Mettler J, Fuchs M, von Tresckow B, Baues C, Rosenwald A, Klapper W, Kobe C, Borchmann P, Engert A
JAMA Oncol 2020 Jun 1;6(6):872-880. doi: 10.1001/jamaoncol.2020.0750. PMID: 32352505Free PMC Article
André MPE, Girinsky T, Federico M, Reman O, Fortpied C, Gotti M, Casasnovas O, Brice P, van der Maazen R, Re A, Edeline V, Fermé C, van Imhoff G, Merli F, Bouabdallah R, Sebban C, Specht L, Stamatoullas A, Delarue R, Fiaccadori V, Bellei M, Raveloarivahy T, Versari A, Hutchings M, Meignan M, Raemaekers J
J Clin Oncol 2017 Jun 1;35(16):1786-1794. Epub 2017 Mar 14 doi: 10.1200/JCO.2016.68.6394. PMID: 28291393
Moskowitz CH, Nademanee A, Masszi T, Agura E, Holowiecki J, Abidi MH, Chen AI, Stiff P, Gianni AM, Carella A, Osmanov D, Bachanova V, Sweetenham J, Sureda A, Huebner D, Sievers EL, Chi A, Larsen EK, Hunder NN, Walewski J; AETHERA Study Group
Lancet 2015 May 9;385(9980):1853-62. Epub 2015 Mar 19 doi: 10.1016/S0140-6736(15)60165-9. PMID: 25796459

Prognosis

Izutsu K, Makita S, Nosaka K, Yoshimitsu M, Utsunomiya A, Kusumoto S, Morishima S, Tsukasaki K, Kawamata T, Ono T, Rai S, Katsuya H, Ishikawa J, Yamada H, Kato K, Tachibana M, Kakurai Y, Adachi N, Tobinai K, Yonekura K, Ishitsuka K
Blood 2023 Mar 9;141(10):1159-1168. doi: 10.1182/blood.2022016862. PMID: 36150143Free PMC Article
Fornecker LM, Lazarovici J, Aurer I, Casasnovas RO, Gac AC, Bonnet C, Bouabdallah K, Feugier P, Specht L, Molina L, Touati M, Borel C, Stamatoullas A, Nicolas-Virelizier E, Pascal L, Lugtenburg P, Di Renzo N, Vander Borght T, Traverse-Glehen A, Dartigues P, Hutchings M, Versari A, Meignan M, Federico M, André M; LYSA-FIL-EORTC Intergroup
J Clin Oncol 2023 Jan 10;41(2):327-335. Epub 2022 Jul 22 doi: 10.1200/JCO.21.01281. PMID: 35867960
Cazelles C, Belhadj K, Vellemans H, Camus V, Poullot E, Gaulard P, Veresezan L, Itti E, Becker S, Carvalho M, Dupuis J, Le Bras F, Lemonnier F, Roulin L, El Gnaoui T, Jardin F, Mounier N, Tilly H, Haioun C
Leuk Lymphoma 2021 Sep;62(9):2161-2168. Epub 2021 Mar 25 doi: 10.1080/10428194.2021.1901090. PMID: 33764240
André MPE, Girinsky T, Federico M, Reman O, Fortpied C, Gotti M, Casasnovas O, Brice P, van der Maazen R, Re A, Edeline V, Fermé C, van Imhoff G, Merli F, Bouabdallah R, Sebban C, Specht L, Stamatoullas A, Delarue R, Fiaccadori V, Bellei M, Raveloarivahy T, Versari A, Hutchings M, Meignan M, Raemaekers J
J Clin Oncol 2017 Jun 1;35(16):1786-1794. Epub 2017 Mar 14 doi: 10.1200/JCO.2016.68.6394. PMID: 28291393
Palanca-Wessels MC, Czuczman M, Salles G, Assouline S, Sehn LH, Flinn I, Patel MR, Sangha R, Hagenbeek A, Advani R, Tilly H, Casasnovas O, Press OW, Yalamanchili S, Kahn R, Dere RC, Lu D, Jones S, Jones C, Chu YW, Morschhauser F
Lancet Oncol 2015 Jun;16(6):704-15. Epub 2015 Apr 27 doi: 10.1016/S1470-2045(15)70128-2. PMID: 25925619

Clinical prediction guides

Fornecker LM, Lazarovici J, Aurer I, Casasnovas RO, Gac AC, Bonnet C, Bouabdallah K, Feugier P, Specht L, Molina L, Touati M, Borel C, Stamatoullas A, Nicolas-Virelizier E, Pascal L, Lugtenburg P, Di Renzo N, Vander Borght T, Traverse-Glehen A, Dartigues P, Hutchings M, Versari A, Meignan M, Federico M, André M; LYSA-FIL-EORTC Intergroup
J Clin Oncol 2023 Jan 10;41(2):327-335. Epub 2022 Jul 22 doi: 10.1200/JCO.21.01281. PMID: 35867960
Cazelles C, Belhadj K, Vellemans H, Camus V, Poullot E, Gaulard P, Veresezan L, Itti E, Becker S, Carvalho M, Dupuis J, Le Bras F, Lemonnier F, Roulin L, El Gnaoui T, Jardin F, Mounier N, Tilly H, Haioun C
Leuk Lymphoma 2021 Sep;62(9):2161-2168. Epub 2021 Mar 25 doi: 10.1080/10428194.2021.1901090. PMID: 33764240
Mazzaro C, Mauro E, Ermacora A, Doretto P, Fumagalli S, Tonizzo M, Toffolutti F, Gattei V
Minerva Med 2021 Apr;112(2):175-187. Epub 2020 Nov 16 doi: 10.23736/S0026-4806.20.07120-7. PMID: 33198444
Shustov A, Soma L
Cancer Treat Res 2019;176:127-144. doi: 10.1007/978-3-319-99716-2_6. PMID: 30596216
Palanca-Wessels MC, Czuczman M, Salles G, Assouline S, Sehn LH, Flinn I, Patel MR, Sangha R, Hagenbeek A, Advani R, Tilly H, Casasnovas O, Press OW, Yalamanchili S, Kahn R, Dere RC, Lu D, Jones S, Jones C, Chu YW, Morschhauser F
Lancet Oncol 2015 Jun;16(6):704-15. Epub 2015 Apr 27 doi: 10.1016/S1470-2045(15)70128-2. PMID: 25925619

Recent systematic reviews

Sickinger MT, von Tresckow B, Kobe C, Engert A, Borchmann P, Skoetz N
Cochrane Database Syst Rev 2015 Jan 9;1(1):CD010533. doi: 10.1002/14651858.CD010533.pub2. PMID: 25572491Free PMC Article
Terasawa T, Lau J, Bardet S, Couturier O, Hotta T, Hutchings M, Nihashi T, Nagai H
J Clin Oncol 2009 Apr 10;27(11):1906-14. Epub 2009 Mar 9 doi: 10.1200/JCO.2008.16.0861. PMID: 19273713

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