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Argyrophilic inclusion bodies

MedGen UID:
866675
•Concept ID:
C4021022
•
Finding
Synonyms: Agyrophilic inclusion bodies; Pick inclusion bodies
 
HPO: HP:0100317

Definition

Presence of abundant argyrophilic grains and coiled bodies on microscopic examination of brain tissue. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVArgyrophilic inclusion bodies

Professional guidelines

PubMed

Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration.
Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL 3rd, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, Yokoo H, Murayama S, Woulfe J, Munoz DG, Dickson DW, Ince PG, Trojanowski JQ, Mann DM; Consortium for Frontotemporal Lobar Degeneration
Acta Neuropathol 2007 Jul;114(1):5-22. Epub 2007 Jun 20 doi: 10.1007/s00401-007-0237-2. PMID: 17579875Free PMC Article
Stains for the differential diagnosis of degenerative dementias.
Munoz DG
Biotech Histochem 1999 Nov;74(6):311-20. doi: 10.3109/10520299909034668. PMID: 10768809
Preliminary NINDS neuropathologic criteria for Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy).
Hauw JJ, Daniel SE, Dickson D, Horoupian DS, Jellinger K, Lantos PL, McKee A, Tabaton M, Litvan I
Neurology 1994 Nov;44(11):2015-9. doi: 10.1212/wnl.44.11.2015. PMID: 7969952

Recent clinical studies

Prognosis

Oligodendroglial and neuronal inclusions in multiple system atrophy.
Costa C, Duyckaerts C
Curr Opin Neurol 1993 Dec;6(6):865-71. doi: 10.1097/00019052-199312000-00007. PMID: 8293161

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