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Abnormal dental enamel morphology

MedGen UID:
867426
•Concept ID:
C4021800
•
Anatomical Abnormality
Synonym: Abnormality of dental enamel
 
HPO: HP:0000682

Definition

An abnormality of the dental enamel. [from HPO]

Conditions with this feature

Tricho-oculo-dermo-vertebral syndrome
MedGen UID:
355714
•Concept ID:
C1866427
•
Disease or Syndrome
See: Condition Record
Tricho-oculo-dermo-vertebral syndrome

Professional guidelines

PubMed

Developmental defects of enamel and dentine: challenges for basic science research and clinical management.
Seow WK
Aust Dent J 2014 Jun;59 Suppl 1:143-54. Epub 2013 Oct 27 doi: 10.1111/adj.12104. PMID: 24164394
Developmental enamel defects in the primary dentition: aetiology and clinical management.
Salanitri S, Seow WK
Aust Dent J 2013 Jun;58(2):133-40; quiz 266. Epub 2013 May 5 doi: 10.1111/adj.12039. PMID: 23713631
Molar incisor hypomineralization: review and recommendations for clinical management.
William V, Messer LB, Burrow MF
Pediatr Dent 2006 May-Jun;28(3):224-32. PMID: 16805354

Recent clinical studies

Etiology

Developmental defects of enamel and dentine: challenges for basic science research and clinical management.
Seow WK
Aust Dent J 2014 Jun;59 Suppl 1:143-54. Epub 2013 Oct 27 doi: 10.1111/adj.12104. PMID: 24164394
Developmental enamel defects in the primary dentition: aetiology and clinical management.
Salanitri S, Seow WK
Aust Dent J 2013 Jun;58(2):133-40; quiz 266. Epub 2013 May 5 doi: 10.1111/adj.12039. PMID: 23713631
A literature review of dental erosion in children.
Taji S, Seow WK
Aust Dent J 2010 Dec;55(4):358-67; quiz 475. doi: 10.1111/j.1834-7819.2010.01255.x. PMID: 21133936
Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasia.
Barron MJ, McDonnell ST, Mackie I, Dixon MJ
Orphanet J Rare Dis 2008 Nov 20;3:31. doi: 10.1186/1750-1172-3-31. PMID: 19021896Free PMC Article
Amelogenesis imperfecta.
Crawford PJ, Aldred M, Bloch-Zupan A
Orphanet J Rare Dis 2007 Apr 4;2:17. doi: 10.1186/1750-1172-2-17. PMID: 17408482Free PMC Article

Diagnosis

Axenfeld-Rieger syndrome: more than meets the eye.
Reis LM, Maheshwari M, Capasso J, Atilla H, Dudakova L, Thompson S, Zitano L, Lay-Son G, Lowry RB, Black J, Lee J, Shue A, Kremlikova Pourova R, Vaneckova M, Skalicka P, Jedlickova J, Trkova M, Williams B, Richard G, Bachman K, Seeley AH, Costakos D, Glaser TM, Levin AV, Liskova P, Murray JC, Semina EV
J Med Genet 2023 Apr;60(4):368-379. Epub 2022 Jul 26 doi: 10.1136/jmg-2022-108646. PMID: 35882526Free PMC Article
Developmental defects of enamel and dentine: challenges for basic science research and clinical management.
Seow WK
Aust Dent J 2014 Jun;59 Suppl 1:143-54. Epub 2013 Oct 27 doi: 10.1111/adj.12104. PMID: 24164394
A literature review of dental erosion in children.
Taji S, Seow WK
Aust Dent J 2010 Dec;55(4):358-67; quiz 475. doi: 10.1111/j.1834-7819.2010.01255.x. PMID: 21133936
Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasia.
Barron MJ, McDonnell ST, Mackie I, Dixon MJ
Orphanet J Rare Dis 2008 Nov 20;3:31. doi: 10.1186/1750-1172-3-31. PMID: 19021896Free PMC Article
Amelogenesis imperfecta.
Crawford PJ, Aldred M, Bloch-Zupan A
Orphanet J Rare Dis 2007 Apr 4;2:17. doi: 10.1186/1750-1172-2-17. PMID: 17408482Free PMC Article

Therapy

Clinical evaluation of resin infiltration treatment masking effect on hypomineralised enamel surfaces.
Altan H, Yilmaz RE
BMC Oral Health 2023 Jul 3;23(1):444. doi: 10.1186/s12903-023-03140-6. PMID: 37400849Free PMC Article
The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis.
Lopes LB, Machado V, Mascarenhas P, Mendes JJ, Botelho J
Sci Rep 2021 Nov 17;11(1):22405. doi: 10.1038/s41598-021-01541-7. PMID: 34789780Free PMC Article
Gene-environment interaction in molar-incisor hypomineralization.
Bezamat M, Souza JF, Silva FMF, Corrêa EG, Fatturi AL, Brancher JA, Carvalho FM, Cavallari T, Bertolazo L, Machado-Souza C, Koruyucu M, Bayram M, Racic A, Harrison BM, Sweat YY, Letra A, Studen-Pavlovich D, Seymen F, Amendt B, Werneck RI, Costa MC, Modesto A, Vieira AR
PLoS One 2021;16(1):e0241898. Epub 2021 Jan 6 doi: 10.1371/journal.pone.0241898. PMID: 33406080Free PMC Article
JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis.
Fragoulis GE, McInnes IB, Siebert S
Rheumatology (Oxford) 2019 Feb 1;58(Suppl 1):i43-i54. doi: 10.1093/rheumatology/key276. PMID: 30806709Free PMC Article
A literature review of dental erosion in children.
Taji S, Seow WK
Aust Dent J 2010 Dec;55(4):358-67; quiz 475. doi: 10.1111/j.1834-7819.2010.01255.x. PMID: 21133936

Prognosis

Deciduous Teeth Hypomineralisation and Perinatal Risk Factors.
Yupanqui K, Bussaneli DG, de Farias AL, Restrepo M, Santos-Pinto L
Monogr Oral Sci 2024;32:147-156. Epub 2024 Jul 1 doi: 10.1159/000538884. PMID: 39321774
Mandibular metastases in neuroblastoma: Outcomes and dental sequelae.
Singh A, Modak S, Solano AK, Kushner BH, Wolden S, Huryn J, Estilo CL
Pediatr Blood Cancer 2021 Apr;68(4):e28918. Epub 2021 Jan 28 doi: 10.1002/pbc.28918. PMID: 33507629Free PMC Article
DDX58 and Classic Singleton-Merten Syndrome.
Ferreira CR, Crow YJ, Gahl WA, Gardner PJ, Goldbach-Mansky R, Hur S, de Jesús AA, Nehrebecky M, Park JW, Briggs TA
J Clin Immunol 2019 Jan;39(1):75-80. Epub 2018 Dec 20 doi: 10.1007/s10875-018-0572-1. PMID: 30574673Free PMC Article
"Pitted" lesions in dermatology.
Adya KA, Inamadar AC, Palit A
Int J Dermatol 2017 Jan;56(1):3-17. Epub 2016 Sep 9 doi: 10.1111/ijd.13358. PMID: 27613605
Molar Incisor Hypomineralization.
Rao MH, Aluru SC, Jayam C, Bandlapalli A, Patel N
J Contemp Dent Pract 2016 Jul 1;17(7):609-13. PMID: 27595731

Clinical prediction guides

Developmental Defects of Enamel.
Martins DDS, Ionta FQ, Pompermaier Garlet G, Lima RR, Neves AA, Rios D, Lussi A
Monogr Oral Sci 2024;32:10-34. Epub 2024 Jul 1 doi: 10.1159/000538850. PMID: 39321764
Orofacial Anomalies in Kindler Epidermolysis Bullosa.
Krämer S, Hillebrecht AL, Wang Y, Badea MA, Barrios JI, Danescu S, Fuentes I, Kartal D, Klausegger A, Ponce de León E, Schilke R, Yordanova I, Bloch-Zupan A, Has C
JAMA Dermatol 2024 May 1;160(5):544-549. doi: 10.1001/jamadermatol.2024.0065. PMID: 38506824Free PMC Article
The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis.
Lopes LB, Machado V, Mascarenhas P, Mendes JJ, Botelho J
Sci Rep 2021 Nov 17;11(1):22405. doi: 10.1038/s41598-021-01541-7. PMID: 34789780Free PMC Article
CRAC channels in dental enamel cells.
Eckstein M, Lacruz RS
Cell Calcium 2018 Nov;75:14-20. Epub 2018 Aug 9 doi: 10.1016/j.ceca.2018.07.012. PMID: 30114531Free PMC Article
Amelogenesis imperfecta.
Crawford PJ, Aldred M, Bloch-Zupan A
Orphanet J Rare Dis 2007 Apr 4;2:17. doi: 10.1186/1750-1172-2-17. PMID: 17408482Free PMC Article

Recent systematic reviews

Dental caries and developmental defects of enamel in cerebral palsy: A meta-analysis.
de Oliveira TN, Drumond VZ, de Arruda JAA, Pani SC, Vargas-Ferreira F, Eustachio RR, Mesquita RA, Abreu LG
Oral Dis 2024 Sep;30(6):3828-3837. Epub 2024 Apr 16 doi: 10.1111/odi.14957. PMID: 38623066
The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis.
Lopes LB, Machado V, Mascarenhas P, Mendes JJ, Botelho J
Sci Rep 2021 Nov 17;11(1):22405. doi: 10.1038/s41598-021-01541-7. PMID: 34789780Free PMC Article
Risk Factors for Early Childhood Caries: A Systematic Review and Meta-Analysis of Case Control and Cohort Studies.
Kirthiga M, Murugan M, Saikia A, Kirubakaran R
Pediatr Dent 2019 Mar 15;41(2):95-112. PMID: 30992106Free PMC Article
Structural, mechanical and chemical evaluation of molar-incisor hypomineralization-affected enamel: A systematic review.
Elhennawy K, Manton DJ, Crombie F, Zaslansky P, Radlanski RJ, Jost-Brinkmann PG, Schwendicke F
Arch Oral Biol 2017 Nov;83:272-281. Epub 2017 Aug 19 doi: 10.1016/j.archoralbio.2017.08.008. PMID: 28843745
Association between developmental defects of enamel and dental caries: A systematic review and meta-analysis.
Vargas-Ferreira F, Salas MM, Nascimento GG, Tarquinio SB, Faggion CM Jr, Peres MA, Thomson WM, Demarco FF
J Dent 2015 Jun;43(6):619-28. Epub 2015 Apr 8 doi: 10.1016/j.jdent.2015.03.011. PMID: 25862273

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